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Research Groups

Research at the IMP is driven by scientific curiosity. Research questions are chosen by each principal investigator and the entire institute works towards supporting the labs’ search for answers. Below, you can find a short summary of the most burning questions that fuel our passion for science and our dedication to research.

Francisco Balzarotti

How can light-based methods provide maximal information on biological processes?

Balzarotti Lab

Meinrad Busslinger

How do transcription factors control the development of B cells and plasma cells?

Busslinger Lab

Tim Clausen

How does the structure of chaperones and proteases that control protein quality relate to their function, and how could this be used to tackle disease and antibiotic resistance?

Clausen Lab

Moritz Gaidt

How does the innate immune system recognize pathogens and induce inflammation?

Gaidt Lab

David Haselbach

How are molecular machines designed to fulfil their productive function? How is the failure of such machines prevented?

Haselbach Lab

Wulf Haubensak

What is the neural basis of emotions and how do genes and drugs control them?

Haubensak Lab

Anna Obenauf

What are the molecular mechanisms behind cancer? How can we exploit the vulnerabilities of cancer cells to find opportunities for new therapies?

Obenauf Lab

Andrea Pauli

What are the molecular mechanisms that drive fertilisation and embryonic development?

Pauli Lab

Rushad Pavri

How do B cells control targeted mutation in the antibody genes to generate a vast repertoire of high-affinity antibodies?

Pavri Lab

Jan-Michael Peters

How can one cell divide into two identical daughter cells in a way that ensures the genome is precisely copied and partitioned?

Peters Lab

Clemens Plaschka

How is mRNA processing regulated, and how do these mechanisms work in atomic detail?

Plaschka Lab

Alexander Stark

How is gene regulation and therefore the development of our bodies encoded in our DNA sequence?

Stark Lab

Elly Tanaka

What gives a stem cell its ability to regenerate into a whole limb, and why is that ability lost in mammals?

Tanaka Lab

Joris van der Veeken

What are the mechanisms that direct T cell differentiation and function?

van der Veeken Lab

Johannes Zuber

Why are cancer cells immortal, what genes do they depend on, and how can we exploit cancer-specific vulnerabilities for cancer therapy?

Zuber Lab

Adjunct Investigators

Adjunct investigators are principal investigators who have moved with their labs from the IMP, but maintain and affiliated status for a certain period of time to support the transition.

David Keays

How do animals sense the earth’s magnetic field? and what genes are required to build a human brain?

Keays Lab

Alipasha Vaziri

How can imaging technologies for the brain-wide recording and manipulation of neural activity be developed to understand how brain structure leads to function?

Vaziri Lab 

Manuel Zimmer

How do neural circuits in the brain compute information to produce behaviour?

Zimmer Lab