BacPROTACs mediate targeted protein degradation in bacteria.Corresponding preprint Cell. 185(13):2338-2353.e18
DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers.Nat Genet. 54(5):613-624
Scroll and browse the latest publications from the IMP. The most recent papers and pre-prints with IMP scientists as first- or corresponding authors.See all
Enhancers display constrained sequence flexibility and context-specific modulation of motif function.Genome Res.
EVI1 drives leukemogenesis through aberrant ERG activation.Blood. 141(5):453-466
Systematic identification and characterization of repressive domains in Drosophila transcription factors.EMBO J. 42(3):e112100
The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells.Front Immunol. 13:859598
Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell-like Program Conserved in HPV-Positive Cancers.Cancer Discov. 13(1):70-84
Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM.Structure. 31(1):4-19
SCON-a Short Conditional intrON for conditional knockout with one-step zygote injection.Exp Mol Med.
Artificial Insemination in Axolotl.Methods Mol Biol. 2562:417-423
Baculovirus Production and Infection in Axolotls.Methods Mol Biol. 2562:369-387