Cohesin mediates DNA loop extrusion by a "swing and clamp" mechanism.Cell. 184(21):5448-5464.e22
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.Nature. 599(7885):491-496
Scroll and browse the latest publications from the IMP. The most recent papers and pre-prints with IMP scientists as first- or corresponding authors.See all
The sperm protein Spaca6 is essential for fertilization in zebrafishbioRxiv . 2021.11.19.469324
A molecular network of conserved factors keeps ribosomes dormant in the eggbioRxiv . 2021.11.03.467131
Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timingbioRxiv . 2021.11.03.467109
The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization.Proc Natl Acad Sci U S A. 118(39)
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.Nat Chem Biol.
The Fertilization Enigma: How Sperm and Egg Fuse.Annu Rev Cell Dev Biol.
Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanomaNature Cancer . 2:693–708
Genome folding through loop extrusion by SMC complexes.Nat Rev Mol Cell Biol. 22(7):445-464