Publications

FlyMAD: rapid thermogenetic control of neuronal activity in freely walking Drosophila.

Microtubules and neurodevelopmental disease: the movers and the makers.

Epigenetic control of immunity.

Central amygdala PKC-δ(+) neurons mediate the influence of multiple anorexigenic signals.

ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.

RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.

Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells.

Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids.

A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.

TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons.

Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.

Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy.

Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.

Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.

Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.

Genome-wide quantitative enhancer activity maps identified by STARR-seq.

Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain.

Identification of transcription factor binding sites from ChIP-seq data at high resolution.

Multiple mechanisms contribute to centriole separation in C. elegans.

Discriminating external and internal causes for heading changes in freely flying Drosophila.

Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates.

Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.

Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain.

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells.

Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD).

Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.

Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.

The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.

CLP1 links tRNA metabolism to progressive motor-neuron loss.

Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.

Interlaboratory studies and initiatives developing standards for proteomics.

Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.

Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes.

Parallel neural pathways mediate CO2 avoidance responses in Drosophila.

Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.

A directional tuning map of Drosophila elementary motion detectors.

A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors.

Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation.

CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis.

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.

Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics.

Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.

Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics.

Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment.

Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho-site localization.

Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light.

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.

Protein-mediated transformation of lipid vesicles into tubular networks.

Regulatory Genomics - Decoding Drosophila Regulatory Sequences.

Wapl is an essential regulator of chromatin structure and chromosome segregation.

High resolution anatomical mapping confirms the absence of a magnetic sense system in the rostral upper beak of pigeons.

Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.

Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans.

Circadian and circalunar clock interactions in a marine annelid.

Discrete neocortical dynamics predict behavioral categorization of sounds.

FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal.

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.

Centrosomes can initiate a polarity axis from any position within one-cell C. elegans embryos.

Methods in cell biology: analysis of cell polarity in C. elegans embryos.

Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities.

The Arabidopsis HEI10 is a new ZMM protein related to Zip3.

Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.

Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment.

A pipeline for the generation of shRNA transgenic mice.

Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3.

Induced heterodimerization and purification of two target proteins by a synthetic coiled-coil tag.

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis.

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.

Dopamine neurons modulate pheromone responses in Drosophila courtship learning.

Analysis of protein mixtures from whole-cell extracts by single-run nanoLC-MS/MS using ultralong gradients.

The blueprint of the type-3 injectisome.

Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain.

HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature.

Auditory circuit in the Drosophila brain.

Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing.

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ.

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.

Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison.

Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies.

A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss.

Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds.

The many functions of cohesin--different rings to rule them all?

Sister chromatid cohesion.

SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments.

Diversity and roles of (t)RNA ligases.

The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis.

CENP-T proteins are conserved centromere receptors of the Ndc80 complex.

Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.

The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior.

Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons.

APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

Cancer stem cell definitions and terminology: the devil is in the details.

Seventy-five genetic loci influencing the human red blood cell.

Reshaping the optical dimension in optogenetics.

Essential role of EBF1 in the generation and function of distinct mature B cell types.

Actin branching in the initiation and maintenance of lamellipodia.

The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions.

Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin.

WNTing embryonic stem cells.

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.

Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding.

Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation.

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis.

GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis.

General statistical modeling of data from protein relative expression isobaric tags.

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

HTRA proteases: regulated proteolysis in protein quality control.

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.

The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells.

Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse.

Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

Using MATLAB to Achieve Nanoscale Optical Sectioning in the Vicinity of Metamaterial Substrates by Simulating Emitter-Substrate Interactions

Functional identification of optimized RNAi triggers using a massively parallel sensor assay.

Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails.

Vibrational excitons in ionophores: experimental probes for quantum coherence-assisted ion transport and selectivity in ion channels

Regulation of GATA-3 expression during CD4 lineage differentiation.

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome.

CTCF-binding elements mediate control of V(D)J recombination.

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.

Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster.

A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.

Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir.

High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species.

Systematic phosphorylation analysis of human mitotic protein complexes.

Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins.

Neural-specific elongation of 3' UTRs during Drosophila development.

Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.

Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex.

An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs.

Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin.

Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.

Comment on 'Jobs for the boys'.

Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications.

Quality control in LC-MS/MS.

Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides.

Epigenetic regulation of learning and memory by Drosophila EHMT/G9a.

A blueprint for kinetochores - new insights into the molecular mechanics of cell division.

A high-resolution map of human evolutionary constraint using 29 mammals.

Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo.

Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation.

Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues.

The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells.

Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component.

Pax5: a master regulator of B cell development and leukemogenesis.

Protein quality control in the bacterial periplasm.

Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.

A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells.

Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development.

Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell.

HSPC117 is the essential subunit of a human tRNA splicing ligase complex.

Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age.

Immersion freezing of biological specimens: rationale, principles, and instrumentation.

Membrane lipidome of an epithelial cell line.

Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.

Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects.

Three-dimensional model of Salmonella's needle complex at subnanometer resolution.

EMCD real space maps of Magnetospirillum magnetotacticum.

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

Universal and confident phosphorylation site localization using phosphoRS.

Substrate-induced remodeling of the active site regulates human HTRA1 activity.

Neuronal control of Drosophila courtship song.

An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.

X inactivation and disease.

Peptide orientation affects selectivity in ion-exchange chromatography.

Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.

CD14 is a coreceptor of Toll-like receptors 7 and 9.

Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.

Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.

Tuba8 is expressed at low levels in the developing mouse and human brain.

Sexual dimorphism in the fly brain.

A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission.

Navigating intermediate targets: the nervous system midline.

Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.

Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films

Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks

Fast near-field imaging of spectrally broad sources using layered metallic structures

Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.

Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4.

The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system.

Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae.

Conversion of a regulatory into a degradative protease.

PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.

Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies.

The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans.

Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase.

Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases.

Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis.

The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus.

Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway.

MIPs are ancestral ligands for the sex peptide receptor.

HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.

The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex.

Polycomb complexes act redundantly to repress genomic repeats and genes.

Probing the phosphoproteome of HeLa cells using nanocast metal oxide microspheres for phosphopeptide enrichment.

MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena.

Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.

From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach.

NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.

STAT5 in B cell development and leukemia.

Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.

Type III secretion systems shape up as they ship out.

Tracing antigen signatures in the human IgE repertoire.

Annexin A1 attenuates EMT and metastatic potential in breast cancer.

A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes.

QIKS--Quantitative identification of kinase substrates.

Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction.

The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.

Photounbinding of calmodulin from a family of CaM binding peptides.

Sororin mediates sister chromatid cohesion by antagonizing Wapl.

An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila.

A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.

Peptide labeling with isobaric tags yields higher identification rates using iTRAQ 4-plex compared to TMT 6-plex and iTRAQ 8-plex on LTQ Orbitrap.

Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.

Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).

The actin cytoskeleton in whole mount preparations and sections.

Sex peptide receptor and neuronal TOR/S6K signaling modulate nutrient balancing in Drosophila.

Casein kinase 1 is required for efficient removal of Rec8 during meiosis I.

High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I.

Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4.

Molecular transformers in the cell: lessons learned from the DegP protease-chaperone.

Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos.

Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.

Systematic genetic analysis of muscle morphogenesis and function in Drosophila.

Topology and organization of the Salmonella typhimurium type III secretion needle complex components.

Distinct protein domains and expression patterns confer divergent axon guidance functions for Drosophila Robo receptors.

Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.

Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.

Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway.

Electron tomography reveals unbranched networks of actin filaments in lamellipodia.

Mcl-1 is essential for germinal center formation and B cell memory.

Organization and coordinated assembly of the type III secretion export apparatus.

Sixteen New Cases Contributing to the Characterization of Patients with Distal 22q11.2 Microduplications.

Cellular organization of the neural circuit that drives Drosophila courtship behavior.

Developmental gene regulation in the era of genomics.

Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.

Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence.

SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells.

Breast cancer stem cells: eradication by differentiation therapy?

Charting the molecular network of the drug target Bcr-Abl.

Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.

BrainGazer--visual queries for neurobiology research.

Automated monitoring to reduce electron microscope downtime.

Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing

An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes.

Turning meiosis into mitosis.

Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.

Reprogramming of Xist against the pluripotent state in fusion hybrids.

The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor.

Defining a superlens operating regime for imaging fluorescent molecules.

RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1.

McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR.

TNFalpha shedding and epidermal inflammation are controlled by Jun proteins.

Central control of fever and female body temperature by RANKL/RANK.

Transcriptional networks controlling skeletal development.

Sensory neurons in the Drosophila genital tract regulate female reproductive behavior.

Peptidic small molecule activators of the stress sensor DegS.

Selectivity profiling of DegP substrates and inhibitors.

Beyond photobleaching, laser illumination unbinds fluorescent proteins.

Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.

Stoichiometry determination of the MP1-p14 complex using a novel and cost-efficient method to produce an equimolar mixture of standard peptides.

A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast.

High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all.

Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I.

ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression.

HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.

X chromosome inactivation sparked by non-coding RNAs.

Optimizing the performance of tin dioxide microspheres for phosphopeptide enrichment.

Comparative genomics of gene regulation-conservation and divergence of cis-regulatory information.

Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli.

Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome.

Preventing carryover of peptides and proteins in nano LC-MS separations.

An innovative method to study target protein-drug interactions by mass spectrometry.

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.

Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.

ANNIE: integrated de novo protein sequence annotation.

With Happyhour, everyone's under the table.

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.

Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.

Cohesin acetylation: from antiestablishment to establishment.

Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity.

Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin.

The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.

Learning the transcriptional regulatory code.

Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis.

Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge.

The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells.

How cohesin and CTCF cooperate in regulating gene expression.

Oct4 to count 2.

Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p.

Moving AHEAD with an international human epigenome project.

A guide to accurate measurement of diffusion using fluorescence correlation techniques with blinking quantum dot nanoparticle labels.

Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.

Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system.

Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia.

Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation.

High-resolution, high-throughput SNP mapping in Drosophila melanogaster.

Developmental plasticity of lymphocytes.

Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to the production of diploid pollen grains.

The Drosophila pheromone cVA activates a sexually dimorphic neural circuit.

Wired for sex: the neurobiology of Drosophila mating decisions.

Podoplanin is a novel fos target gene in skin carcinogenesis.

Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.

Role of Growth factors in Bone development and differentiation.

Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.

When flies and mice develop cancer. Meeting on development and cancer.

B young again.

Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2.

Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation.

The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion.

Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.

Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis.

Targeting c-Jun and JunB proteins as potential anticancer cell therapy.

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells.

The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.

Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.

Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation.

Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.

GraFix: sample preparation for single-particle electron cryomicroscopy.

JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion.

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

The Suv39h-HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells.

EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer.

The different functions of Stat5 and chromatin alteration through Stat5 proteins.

Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins.

Structural basis for the regulated protease and chaperone function of DegP.

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.

SHOC1, an XPF endonuclease-related protein, is essential for the formation of class I meiotic crossovers.

Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation.

Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control.

DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena.

Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.

PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.

Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons.

Checkpoint control: the journey continues.

The cohesin complex and its roles in chromosome biology.

Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.

Arabidopsis SMG7 protein is required for exit from meiosis.

Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases.

Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis.

Enhanced detection and identification of multiply phosphorylated peptides using TiO2 enrichment in combination with MALDI TOF/TOF MS.

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.

Transcript versus transcription?

Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation.

Unravelling the structure of the lamellipodium.

Ca2+/Calmodulin-dependent kinase II signaling causes skeletal overgrowth and premature chondrocyte maturation.

Polo and Aurora kinases: lessons derived from chemical biology.

The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions.

Twenty years of cell-cycle conferences in Roscoff.

Antagonistic control of cell fates by JNK and p38-MAPK signaling.

Developmentally informed research on the effectiveness of clinical trials: a primer for assessing how developmental issues may influence treatment responses among adolescents with alcohol use problems.

Architecture and flexibility of the yeast Ndc80 kinetochore complex.

Cohesin mediates transcriptional insulation by CCCTC-binding factor.

14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation.

c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene.

A receptor that mediates the post-mating switch in Drosophila reproductive behaviour.

Identification of the human homolog of the imprinted mouse Air non-coding RNA.

Neuroscience: hidden female talent.

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease.

The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.

The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch.

ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin.

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.

Differential regulation of Foxo3a target genes in erythropoiesis.

Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.

In vitro differentiation of murine embryonic stem cells toward a renal lineage.

Identification of new targets using expression profiling.

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.

Pax5: the guardian of B cell identity and function.

Ran and Rac in mouse eggs: cortical polarity and spindle positioning.

Acto-myosin reorganization and PAR polarity in C. elegans.

Neurobiology of behaviour.

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.

Simultaneous generation of fra-2 conditional and fra-2 knock-out mice.

PSD-95 is required for activity-driven synapse stabilization.

The ring between ring fingers (RBR) protein family.

Posttranslational modifications and subcellular localization signals: indicators of sequence regions without inherent 3D structure?

Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.

PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression.

Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.

Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.

The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity.

Tandem affinity purification of functional TAP-tagged proteins from human cells.

The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation.

The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer.

Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias.

MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.

Skeletal development--Wnts are in control.

Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.

Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase.

Dscam diversity is essential for neuronal wiring and self-recognition.

Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling.

p53 is regulated by the lysine demethylase LSD1.

p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway.

p38alpha: a suppressor of cell proliferation and tumorigenesis.

Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing.

A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database.

Function of the Drosophila CPEB protein Orb2 in long-term courtship memory.

Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.

Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.

A single class of olfactory neurons mediates behavioural responses to a Drosophila sex pheromone.

Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells.

The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes.

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.

Life beyond cleavage: the case of Ago2 and hematopoiesis.

Towards complete sets of farnesylated and geranylgeranylated proteins.

Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis.

DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.

LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit.

The complete removal of cohesin from chromosome arms depends on separase.

pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model.

Xist and the order of silencing.

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

JunB is a gatekeeper for B-lymphoid leukemia.

A chemical proteomics approach to phosphatidylinositol 3-kinase signaling in macrophages.

A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination.

The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis.

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.

Cell biology: the checkpoint brake relieved.

Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle.

c-Myc is required for transformation of FDC-P1 cells by EGFRvIII.

Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.

Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5.

Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes.

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.

The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila.

Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high-resolution mass spectrometry, and computational modeling.

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.

Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus.

BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.

Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions.

Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes.

A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene.

Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.

Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action.

Molecular biology. How and when the genome sticks together.

RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Xist function: bridging chromatin and stem cells.

X inactivation Xplained.

NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.

The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches.

Epigenetics

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.

Protein prenylation: an (almost) comprehensive overview on discovery history, enzymology and significance in physiology and disease.

Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.

Wiring stability of the adult Drosophila olfactory circuit after lesion.

Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.

The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division.

The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.

Netrins guide Drosophila commissural axons at short range.

Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization.

Histone modification patterns associated with the human X chromosome.

How APC/C orders destruction.

Epigenetic control of lymphopoiesis.

A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced.

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

Regulation of commissural axon pathfinding by slit and its Robo receptors.

Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR.

Biomolecular Mechanisms with Computational Biology

The polycomb group protein EZH2 is required for mammalian circadian clock function.

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.

Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.

Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication.

A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes.

The role of human HtrA1 in arthritic disease.

High-throughput knockout screen in fission yeast.

Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.

Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.

Bone and Cartilage.

A Wnt canon orchestrating osteoblastogenesis.

Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1.

Multiple roles of mesenchymal beta-catenin during murine limb patterning.

Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.

Repression of p53 activity by Smyd2-mediated methylation.

Mitotic activation of the kinase Aurora-A requires its binding partner Bora.

Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex.

Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin.

Autocrine PDGFR signaling promotes mammary cancer metastasis.

The epigenetic magic of histone lysine methylation.

Regulation of cancer cell migration and bone metastasis by RANKL.

STAT1 acts as a tumor promoter for leukemia development.

Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex.

The role of histone modifications in epigenetic transitions during normal and perturbed development.

Wapl controls the dynamic association of cohesin with chromatin.

Shared neural circuitry for female and male sexual behaviours in Drosophila.

A central role for central tolerance.

Checkpoint activation: don't get mad too much.

Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.

HPLC techniques for proteomics analysis--a short overview of latest developments.

Phosphoproteomics strategies for the functional analysis of signal transduction.

Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise.

DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity.

Post-transcriptional regulation of microRNA expression.

The anaphase promoting complex/cyclosome: a machine designed to destroy.

Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.

T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17.

Electron Microscopy of Extracted Cytoskeletons: Negative Staining, Cryoelectron Microscopy and Correlation with Light Microscopy.

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation.

Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation.

Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases.

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.

Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis.

Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27.

Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.

Role of canonical Wnt-signalling in joint formation.

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis.

Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes.

c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity.

Application of different fragmentation techniques for the analysis of phosphopeptides using a hybrid linear ion trap-FTICR mass spectrometer.

The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.

fruitless regulates aggression and dominance in Drosophila.

ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells.

Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes.

Cohesin and DNA damage repair.

Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.

Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons.

Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.

Sexual behaviour: do a few dead neurons make the difference?

Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors.

AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene.

Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse.

Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells.

Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.

Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte.

The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway.

Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.

Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire.

Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.

Oncogene-induced senescence as an initial barrier in lymphoma development.

Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth.

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling.

Essential role of RSK2 in c-Fos-dependent osteosarcoma development.

Expansion and differentiation of immature mouse and human hematopoietic progenitors.

The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability.

Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.

DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells.

Bioinformatics: Mystery, Astrology or Service Technology. Preface for "Discovering Biomolecular Mechanisms with Computational Biology"

Prediction of the Protein Function: Two Basic Concepts and One Practical Recipe. Chapter 3 in

Discovering Biomolecular Mechanisms with Computational Biology.

Sequence complexity of proteins and its significance in annotation.

Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis.

Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.

The molecular clock mediates leptin-regulated bone formation.

Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor.

The molecular requirements for cytokinesis.

Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.

Implications of the serine protease HtrA1 in amyloid precursor protein processing.

Cell size control: new evidence for a general mechanism.

Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.

SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.

Molecular machines for protein degradation.

Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis.

Molecular processes during fat cell development revealed by gene expression profiling and functional annotation.

A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions.

Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.

CD44 is a determinant of inflammatory bone loss.

Identification of cell cycle-dependent phosphorylation sites on the anaphase-promoting complex/cyclosome by mass spectrometry.

Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome.

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.

Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin.

Molecular requirements for epithelial-mesenchymal transition during tumor progression.

A topological interaction between cohesin rings and a circular minichromosome.

Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.

Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex.

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing.

Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.

The 1.3 A crystal structure of the flavoprotein YqjM reveals a novel class of Old Yellow Enzymes.

Selection and behavior of CD4+ CD25+ T cells in vivo: lessons from T cell receptor transgenic models.

JNK1 is not essential for TNF-mediated joint disease.

EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells.

The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates.

Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors.

TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen.

The profile of repeat-associated histone lysine methylation states in the mouse epigenome.

Tumor cell invasiveness correlates with changes in integrin expression and localization.

Refinement and prediction of protein prenylation motifs.

Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells.

Fos and jun proteins are specifically expressed during differentiation of human keratinocytes.

Stat5 tetramer formation is associated with leukemogenesis.

How do so few control so many?

How might cohesin hold sister chromatids together?

The structure and function of SMC and kleisin complexes.

Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.

Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family.

PhyloDome--visualization of taxonomic distributions of domains occurring in eukaryote protein sequence sets.

Species specific membrane anchoring of nyctalopin, a small leucine-rich repeat protein.

Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow.

Cyclin degradation: don't mes(s) with meiosis.

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.

Distinct functions of junD in cardiac hypertrophy and heart failure.

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.

I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss.

BCR/ABL promotes dendritic cell-mediated natural killer cell activation.

TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent.

Fos/AP-1 proteins in bone and the immune system.

Introduction: dissection and simplification of chromosome segregation.

Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.

The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint.

Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes.

Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus.

FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1.

Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells.

Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.

Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates.

Tissue-specific expression of cre recombinase from the Pax8 locus.

A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

Transcriptional control of early B cell development.

Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells.

Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates.

TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter.

Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle.

Evidence for a size-sensing mechanism in animal cells.

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila.

The Fos-related antigen Fra-1 is an activator of bone matrix formation.

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.

Proteolysis as a regulatory mechanism.

Prediction of sequence signals for lipid post-translational modifications: insights from case studies.

A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Structural and functional impairment of an Old Yellow Enzyme homologue upon affinity tag incorporation.

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene.

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

Regulation of sister chromatid cohesion between chromosome arms.

Cleavage furrow positioning.

Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation.

Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.

Structure and stability of cohesin's Smc1-kleisin interaction.

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.

The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions.

Hypoxic induction of Ctgf is directly mediated by Hif-1.

[Setting the stage for mitosis: kinase regulation of prophase].

Distinct functions of condensin I and II in mitotic chromosome assembly.

Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

Epithelial-mesenchymal transition: NF-kappaB takes center stage.

Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.

Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.

Targeted gene knockout reveals a role in meiotic recombination for ZHP-3, a Zip3-related protein in Caenorhabditis elegans.

Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling.

The AP1 transcription factor Fra2 is required for efficient cartilage development.

Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.

Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion during yeast meiosis.

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects.

Polyomavirus tumorantigens have a profound effect on gene expression in mouse fibroblasts.

A chromosomal memory triggered by Xist regulates histone methylation in X inactivation.

A crack in histone lysine methylation.

Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice.

Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes.

Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3.

Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome.

Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes.

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

S. pombe meiotic linear elements contain proteins related to synaptonemal complex components.

Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells.

The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation.

Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.

Myristoylation of viral and bacterial proteins.

MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins.

JunD regulates lymphocyte proliferation and T helper cell cytokine expression.

Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation.

Cell cycle regulation of central spindle assembly.

Automated, on-line two-dimensional nano liquid chromatography tandem mass spectrometry for rapid analysis of complex protein digests.

Changing places. Interview by Graham Tebb.

From a single double helix to paired double helices and back.

Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins.

SUMO conjugation in plants.

Linking transcriptional mediators via the GACKIX domain super family.

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.

Generation and characterization of methyl-lysine histone antibodies.

Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II.

Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II.

The AP-1 transcription factor c-Jun is required for efficient axonal regeneration.

Is chromatin remodeling required to build sister-chromatid cohesion?

Normal mineralization and nanostructure of sclerotic bone in mice overexpressing Fra-1.

Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation.

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation.

Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.

The indexing potential of histone lysine methylation.

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.

Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.

Roles of polo-like kinase 1 in the assembly of functional mitotic spindles.

Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.

IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.

Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth.

Sheet preparations expose the dermal nerve plexus of human skin and render the dermal nerve end organ accessible to extensive analysis.

Muscle regeneration and myogenic differentiation defects in mice lacking TIS7.

The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity.

APC/C and SCF: controlling each other and the cell cycle.

APC activators caught by their tails?

Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase.

MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.

Inhibitory effect of TIS7 on Sp1-C/EBPalpha transcription factor module activity.

GermOnline, a cross-species community knowledgebase on germ cell differentiation.

Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.

Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.

Heat shock protein 70 (Hsp70) subtype expression in neuroendocrine tissue and identification of a neuroendocrine tumour-specific Hsp70 truncation.

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.

Wnt signalling regulates myogenic differentiation in the developing avian wing.

ATP hydrolysis is required for cohesin's association with chromosomes.

Impaired intervertebral disc formation in the absence of Jun.

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.

Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1.

Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19.

Maintenance of stable heterochromatin domains by dynamic HP1 binding.

Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I.

The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells.

Centrosome separation and central spindle assembly act in redundant pathways that regulate microtubule density and trigger cleavage furrow formation.

Development. Wiring the brain with insulin.

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53.

AP-1: a double-edged sword in tumorigenesis.

Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins.

Glycosylphosphatidylinositol lipid anchoring of plant proteins. Sensitive prediction from sequence- and genome-wide studies for Arabidopsis and rice.

Prediction of Post-translational modifications from amino acid sequence: Problems, pitfalls, methodological hints.

Prediction of lipid posttranslational modifications and localization signals from protein sequences: big-Pi, NMT and PTS1.

Measuring Generality of Knowledge-Based Potential Extracted from Protein Structure Sets.

Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development.

Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.

Rhabdomyosarcoma development in mice lacking Trp53 and Fos: tumor suppression by the Fos protooncogene.

Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression.

Formation of facultative heterochromatin in the absence of HP1.

Cytokinesis: progress on all fronts.

Molecular shredders: how proteasomes fulfill their role.

Chromosomal cohesin forms a ring.

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

Building and breaking bridges between sister chromatids.

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling.

Wnts in limb bud development.

Fine tuning of kinetochore function by phosphorylation.

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.

Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors.

Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells.

Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase.

Expression profiling of epithelial plasticity in tumor progression.

Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state.

Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling.

Mitotic entry: tipping the balance.

Mitotic regulation of the human anaphase-promoting complex by phosphorylation.

Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs.

An epigenetic road map for histone lysine methylation.

Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling.

Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.

Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels.

The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains.

Protein prenyltransferases.

Protein prenyltransferases: anchor size, pseudogenes and parasites.

N-ras mutation in a canine lymphoma: short communication.

K-ras mutations in canine pancreatic cancers.

K-ras protooncogene mutations in feline pancreatic adenocarcinomas.

N-ras mutations in canine malignant melanomas.

The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.

Cytokinesis: a logical GAP.

An improved method for tracking and reducing the void volume in nano HPLC-MS with micro trapping columns.

Motif refinement of the peroxisomal targeting signal 1 and evaluation of taxon-specific differences.

Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence.

The STIR-domain superfamily in signal transduction, development and immunity.

Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.

Emi1 proteolysis: how SCF(beta-Trcp1) helps to activate the anaphase-promoting complex.

Un ménage à quatre: the molecular biology of chromosome segregation in meiosis.

Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.

Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade.

The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex.

CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1.

Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.

Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun.

Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.

Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells.

Granulocyte-macrophage colony-stimulating factor-based melanoma cell vaccines immunize syngeneic and allogeneic recipients via host dendritic cells.

Flamingo regulates R8 axon-axon and axon-target interactions in the Drosophila visual system.

Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart.

Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.

Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction.

JunB inhibits proliferation and transformation in B-lymphoid cells.

The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1.

Thymic selection revisited: how essential is it?

Signalling in osteoclasts and the role of Fos/AP1 proteins.

Reannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenoviruses.

JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun.

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.

Induction of short interspersed nuclear repeat-containing transcripts in epithelial cells upon infection with a chicken adenovirus.

Quantitative measurement of cell migration using time-lapse videomicroscopy and non-linear system analysis.

Xist RNA associates with chromatin and causes gene silencing.

RNAs templating chromatin structure for dosage compensation in animals.

Identification of a subunit of a novel Kleisin-beta/SMC complex as a potential substrate of protein phosphatase 2A.

c-Jun regulates eyelid closure and skin tumor development through EGFR signaling.

Promoter specificity and biological activity of tethered AP-1 dimers.

Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver.

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila.

Nephric lineage specification by Pax2 and Pax8.

Cadherins and the tumour progression: is it all in a switch?

On filtering false positive transmembrane protein predictions.

JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms.

Molecular mechanisms of axon guidance.

Netrins.

Axon guidance: growth cones make an unexpected turn.

Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts.

FGF signaling regulates expression of Tbx2, Erm, Pea3, and Pax3 in the early nasal region.

Overexpression of vascular endothelial growth factor-A165 enhances tumor angiogenesis but not metastasis during beta-cell carcinogenesis.

Cytokinesis: regulated by destruction.

Inhibition of proliferation and expression of T1 and cyclin D1 genes by thyroid hormone in mammary epithelial cells.

Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.

The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo.

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis.

Molecular architecture of SMC proteins and the yeast cohesin complex.

Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.

Rac function and regulation during Drosophila development.

Recent advances in cancer research: mouse models of tumorigenesis.

Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis.

Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.

Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway.

Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling.

Molecular biology. An RNA-guided pathway for the epigenome.

The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis.

A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo.

Reaching a genetic and molecular understanding of skeletal development.

Comm sorts robo to control axon guidance at the Drosophila midline.

Raf-1 antagonizes erythroid differentiation by restraining caspase activation.

Epigenetics: SUPERMAN dresses up.

The many faces of histone lysine methylation.

Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.

Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus.

Mammalian septins nomenclature.

Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component.

N-terminal N-myristoylation of proteins: prediction of substrate proteins from amino acid sequence.

N-terminal N-myristoylation of proteins: refinement of the sequence motif and its taxon-specific differences.

Canine N-ras oncogene-mutation in a case of malignant melanoma in the brain.

Feline tumour suppressor gene p53 - Mutation in a case of bronchial gland carcinoma

N-ras mutation in a feline lymphoma. Low frequency of N-ras mutations in a series of feline, canine and bovine lymphomas.

Tumour suppressor gene p53 mutation in a case of haemangiosarcoma of a dog.

GTP binding induces filament assembly of a recombinant septin.

Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.

Reversion of B cell commitment upon loss of Pax5 expression.

Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity.

Segregating sister genomes: the molecular biology of chromosome separation.

Rac GTPases control axon growth, guidance and branching.

A CH domain-containing N terminus in NuMA?

JunB can substitute for Jun in mouse development and cell proliferation.

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

Anaphase-promoting complex.

The anaphase-promoting complex: proteolysis in mitosis and beyond.

The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers.

Osteoclasts are essential for TNF-alpha-mediated joint destruction.

Transcriptional control of B-cell development.

Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene.

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.

MLL-ENL cooperates with SCF to transform primary avian multipotent cells.

Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.

High troughput mass-spectrometry for proteomics analysis.

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation.

The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.

Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.

RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta.

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections.

Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila.

Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.

TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells.

Conspiracy to disarm APC in interphase.

Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis.

Functions of AP1 (Fos/Jun) in bone development.

Regulation of human separase by securin binding and autocleavage.

Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis.

Amino-terminal phosphorylation of c-Jun regulates apoptosis in the retinal ganglion cells by optic nerve transection.

Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast.

Expression of members of the Fgf family and their receptors during midfacial development.

Ubiquitylation in plants: a post-genomic look at a post-translational modification.

Nuclear receptors in hematopoietic development: cooperation with growth factor receptors in regulation of proliferation and differentiation.

Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT).

Genetic mapping with SNP markers in Drosophila.

Keratinocyte-specific onset of serine protease BSSP expression in experimental carcinogenesis.

Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division.

Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough.

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.

Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.

Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium.

Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF.

Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice.

Rho GTPases in growth cone guidance.

Developmental neuroscience. Moving on.

Making connections. Meeting: axon guidance and neural plasticity.

Establishment of normal, terminally differentiating mouse erythroid progenitors: molecular characterization by cDNA arrays.

Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes.

The Brix domain protein family -- a key to the ribosomal biogenesis pathway?

The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.

Three-dimensional structure of the anaphase-promoting complex.

Microtubule-independent motility and nuclear targeting of adenoviruses with fluorescently labeled genomes.

Animal cell cytokinesis.

AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun.

Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.

E-cadherin

G1-Cdk activity is required for both proliferation and viability of cytokine-dependent myeloid and erythroid cells.

The role of PAX5 (BSAP) in early and late B-cell development.

Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.

Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila.

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells.

Securin is required for chromosomal stability in human cells.

Re-SET-ting heterochromatin by histone methyltransferases.

Translating the histone code.

Protective role of Raf-1 in Salmonella-induced macrophage apoptosis.

AP-1 in mouse development and tumorigenesis.

Short- and long-range repulsion by the Drosophila Unc5 netrin receptor.

The Drosophila nervous system as a model for asymmetric cell division.

Asymmetric cell division during animal development.

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

FGF signaling is necessary for the specification of the odontogenic mesenchyme.

Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.

Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting.

Lack of sequence variation in sporadic bovine leucosis in regions of tumour suppressor genes p53 and p16.

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene.

Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system.

Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis.

A prize for proliferation.

Splitting the chromosome: cutting the ties that bind sister chromatids.

Exciting future planned for birthplace of genetics.

Rb targets histone H3 methylation and HP1 to promoters.

Can molecular mechanisms of biological processes be extracted from expression profiles? Case study: endothelial contribution to tumor-induced angiogenesis.

Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis.

The polycomb-group gene Ezh2 is required for early mouse development.

DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression.

A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction.

Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage.

Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex.

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.

DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.

Translation control: bridging the gap between genomics and proteomics?

A screen for genes required for meiosis and spore formation based on whole-genome expression.

Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability.

Mammary gland development and lactation are controlled by different glucocorticoid receptor activities.

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex.

c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation.

Protein localization during asymmetric cell division.

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system.

Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans.

Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells.

E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity.

Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.

Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes.

A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.

Defining CAR as a cellular receptor for the avian adenovirus CELO using a genetic analysis of the two viral fibre proteins.

The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.

Expression of collagenase-3 (MMP-13) in c-fos-induced osteosarcomas and chondrosarcomas is restricted to a subset of cells of the osteo-/chondrogenic lineage.

Perturbation of the tight junction permeability barrier by occludin loop peptides activates beta-catenin/TCF/LEF-mediated transcription.

Cell cycle: Waiters serving the Destruction machinery.

Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis.

AP-1--Introductory remarks.

Genetic control of skeletal development.

Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex.

Taxonomy workbench.

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment.

Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.

Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8.

Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres.

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation.

Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association.

Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.

Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus.

Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin.

Lineage commitment in lymphopoiesis.

Molecular mechanisms of tumor angiogenesis and tumor progression.

Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.

Recent advances in research on multistage tumorigenesis.

Fibroblast growth factors are required for efficient tumor angiogenesis.

Genetics. Reverse gear for Drosophila.

Characterisation of the rubber elongation factor from ammoniated latex by electrophoresis and mass spectrometry.

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family.

Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity.

Automated annotation of GPI anchor sites: case study C. elegans.

Fra-1 replaces c-Fos-dependent functions in mice.

The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components.

Erythroid cell development and leukemic transformation: interplay between signal transduction, cell cycle control and oncogenes.

Cullins and cell cycle control.

Activation of heat-shock response by an adenovirus is essential for virus replication.

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.

Altered subcellular distribution of cadherin-5 in endothelial cells caused by the serum of pre-eclamptic patients.

Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.

Transgenic activation of Ras in neurons promotes hypertrophy and protects from lesion-induced degeneration.

The puzzle of size control in organisms.

Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells.

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis.

Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1.

Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis.

Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation.

Epithelial polarity: the ins and outs of the fly epidermis.

c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents.

Mitotic regulation of the APC activator proteins CDC20 and CDH1.

Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE.

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells.

Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation.

Presence of p53 mutations in feline neoplasms.

Comparative studies in the promoter and exon 1 regions of tumour suppressor p53 in several mammalian species: absence of mutations in a panel of spontaneous domestic animal tumours.

Activation of the beta globin locus by transcription factors and chromatin modifiers.

Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.

Isolation of translationally controlled mRNAs by differential screening.

Regulation of ferritin mRNA translation in primary erythroblasts: exogenous c-Kit plus EpoR signaling mimics v-ErbA oncoprotein activity.

Splitting the chromosome: cutting the ties that bind sister chromatids.

Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.

Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila.

Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.

A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry.

Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth.

Pds5 cooperates with cohesin in maintaining sister chromatid cohesion.

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression.

Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.

TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest.

Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.

Crossing the midline: roles and regulation of Robo receptors.

Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS.

Regulation of chromatin structure by site-specific histone H3 methyltransferases.

A syndrome involving intrauterine growth retardation, microcephaly, cerebellar hypoplasia, B lymphocyte deficiency, and progressive pancytopenia.

Fidelity and infidelity in commitment to B-lymphocyte lineage development.

Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast.

A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila.

Placental vascularisation requires the AP-1 component fra1.

brakeless is required for lamina targeting of R1-R6 axons in the Drosophila visual system.

The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest.

The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.

Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.

Characterization of vertebrate cohesin complexes and their regulation in prophase.

Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.

Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation.

Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.

Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i.

Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.

Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway.

Protein kinase C alpha controls erythropoietin receptor signaling.

Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase.

JunD protects cells from p53-dependent senescence and apoptosis.

Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.

Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage.

Variations of p53 in cultured fibroblasts of patients with lung cancer who have a presumed genetic predisposition.

The glucocorticoid receptor is required for stress erythropoiesis.

A putative role for c-Fos in the pathophysiology of Paget's disease.

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation.

Transient transfection of mammary epithelial cells with a PEI/DNA/adenovirus system.

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.

The IGF/IGF-1 receptor signaling pathway as a potential target for cancer therapy.

An insulin-like growth factor-mediated, phosphatidylinositol 3' kinase-independent survival signaling pathway in beta tumor cells.

The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.

Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.

Receptor-mediated gene delivery strategies.

twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development.

Role of the ATFa/JNK2 complex in Jun activation.

Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.

Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.

The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins.

Functions of c-Jun in liver and heart development.

Getting informed in bioinformatics

Prediction of potential GPI-modification sites in proprotein sequences.

Hydrophobic regions on protein surfaces.

Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets.

Endocytic organelles: Methods for preparation.

Loss of epithelial polarity is accompanied by differential association of proteins with intracellular membranes.

Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells.

TGF-beta cooperates with TGF-alpha to induce the self-renewal of normal erythrocytic progenitors: evidence for an autocrine mechanism.

Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons.

Chromosome segregation: Samurai separation of Siamese sisters.

ASH1 mRNA localization in yeast involves multiple secondary structural elements and Ash1 protein translation.

Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex.

An unexpected role for p53 in augmenting SV40 large T antigen-mediated tumorigenesis.

The use of in vitro expanded erythroid cells in a model system for the isolation of fetal cells from maternal blood.

Depletion of syntaxins in the early Caenorhabditis elegans embryo reveals a role for membrane fusion events in cytokinesis.

[Loss of junB expression causes a myeloproliferative syndrome resembling chronic myeloid leukemia].

GRC5 and NMD3 function in translational control of gene expression and interact genetically.

A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.

Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization.

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines.

T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density.

The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.

Molecular calculations on the conformation of the HIV-1 reverse transcriptase inhibitor 1-[(2-Hydroxyethoxy)methyl]-6-[phenylthio]-thymine [HEPT].

Conformational study of the HIV-1 reverse transcriptase inhibitor 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).

Characterization of CELO virus proteins that modulate the pRb/E2F pathway.

Self-renewal, maturation, and differentiation of the rat myelomonocytic hematopoietic stem cell.

Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.

Function of Fos proteins in bone cell differentiation.

Mutational analysis of the avian adenovirus CELO, which provides a basis for gene delivery vectors.

Impaired ferritin mRNA translation in primary erythroid progenitors: shift to iron-dependent regulation by the v-ErbA oncoprotein.

Post-transcriptional control via iron-responsive elements: the impact of aberrations in hereditary disease.

Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.

Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene.

Separating sister chromatids.

The IMP and European molecular biology: moving the centre eastwards. Institute of Molecular Pathology.

Finishing the cell cycle.

Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5.

The molecular basis of B-cell lineage commitment.

Independent regulation of the two Pax5 alleles during B-cell development.

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton.

Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines.

Subcellular fractionation, electromigration analysis and mapping of organelles.

FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts.

Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

Subunits and substrates of the anaphase-promoting complex.

Differentiation, dedifferentiation, and redifferentiation of B-lineage lymphocytes: roles of the surrogate light chain and the Pax5 gene.

Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors.

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.

JunB is essential for mammalian placentation.

Control of cell cycle progression by c-Jun is p53 dependent.

Pax2/5 and Pax6 subdivide the early neural tube into three domains.

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.

Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma.

Identification of cohesin association sites at centromeres and along chromosome arms.

Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.

Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1.

Fibroblast growth factors in tumor progression and angiogenesis.

The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro.

Genetically modified mice as tolls for cancer research.

A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor.

Whose end is destruction: cell division and the anaphase-promoting complex.

The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors.

recessive spotting: a linked locus that interacts with W/Kit but is not allelic.

Chemically defined, cell-free cancer vaccines: use of tumor antigen-derived peptides or polyepitope proteins for vaccination.

Role of the transcription factor BSAP [Pax-5] in B-cell development.

The implications of angiogenesis on tumor invasiveness.

Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.

An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast.

Transfection complexes generated with adenovirus and polyethylenimine-condensed DNA.

Transformation of hematopoietic cells by the Ski oncoprotein involves repression of retinoic acid receptor signaling.

Three-dimensional organotypic growth of epithelial cells in reconstituted extracellular matrix.

Cell multiplication - editorial overview.

Preparation and purification of post-golgi vesicles from perforated Madin-Darby Canine Kidney Cells.

SET domain proteins modulate chromatin domains in eu- and heterochromatin.

Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family.

Impairment of survival factor function potentiates chemotherapy-induced apoptosis in tumor cells.

A multithreaded Java framework for solving linear elliptic partial differential equations in 3D.

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis.

Novel p53 tumour suppressor mutations in cases of spindle cell sarcoma, pleomorphic sarcoma and fibrosarcoma in cats.

Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma.

Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation.

Neisseria gonorrhoeae porin modulates phagosome maturation.

Model scenarios for evolution of the eukaryotic cell cycle.

Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments.

TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis.

The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.

Embryonic overexpression of the c-Fos protooncogene. A murine stem cell chimera applicable to the study of fibrodysplasia ossificans progressiva in humans.

Assignment of the gene encoding the core promoter element binding protein (COPEB) to human chromosome 10p15 by somatic hybrid analysis and fluorescence in situ hybridization.

Molecular cloning and expression analysis of five novel genes in chromosome 1p36.

A causal role for E-cadherin in the transition from adenoma to carcinoma.

SCF and APC: the Yin and Yang of cell cycle regulated proteolysis.

Cell cycle control by ubiquitin-dependent proteolysis.

Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.

The tumor-suppressor function of E-cadherin.

The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae.

A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor.

Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases.

Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.

Cohesion between sister chromatids must be established during DNA replication.

Translational fidelity: error-prone versus hyper-accurate ribosomes.

The transactivation domain AF-2 but not the DNA-binding domain of the estrogen receptor is required to inhibit differentiation of avian erythroid progenitors.

Regulation of the cyclin B degradation system by an inhibitor of mitotic proteolysis.

Oncogene function in normal development and disease.

Mammalian granulocyte-macrophage colony-stimulating factor receptor expressed in primary avian hematopoietic progenitors: lineage-specific regulation of proliferation and differentiation.

Identification of a cullin homology region in a subunit of the anaphase-promoting complex.

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex.

Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase.

Delivery of bacterial artificial chromosomes into mammalian cells with psoralen-inactivated adenovirus carrier.

Polyethylenimine (PEI) is a simple, inexpensive and effective reagent for condensing and linking plasmid DNA to adenovirus for gene delivery.

Analysis of the requirement for beta 2-microglobulin for expression and formation of human CD1 antigens.

Mechanism of transformation by v-ErbA: substitution for steroid hormone receptor function in self renewal induction.

Cell Biologists sort things out: Analysis and purification of intracellular organelles by flow cytometry.

Fluorescence activated sorting of endocytic organelles.

Isolation and amino acid sequence analysis reveal an ancient evolutionary origin of the cleavage stage (CS) histones of the sea urchin.

Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis.

Transloading of tumor antigen-derived peptides into antigen-presenting cells.

Identification of a novel antiapoptotic protein, GAM-1, encoded by the CELO adenovirus.

ICE-proteases mediate HTLV-I Tax-induced apoptotic T-cell death.

The role of fibroblast growth factors in tumor progression and angiogenesis.

Novel forms of acidic fibroblast growth factor-1 are constitutively exported by beta tumor cell lines independent from conventional secretion and apoptosis.

In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer.

Intracellular delivery of lipopolysaccharide during DNA transfection activates a lipid A-dependent cell death response that can be prevented by polymyxin B.

The characterization of novel Pax genes of the sea urchin and Drosophila reveal an ancient evolutionary origin of the Pax2/5/8 subfamily.

Regulation of human epsilon germline transcription: role of B-cell-specific activator protein.

A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos.

Subcellular fractionation of polarized epithelial cells and identification of organelle-specific proteins by two-dimensional gel electrophoresis.

Structure and erythroid cell-restricted expression of a chicken cDNA encoding a novel zinc finger protein of the Cys + His class.

The mechanism and control of cytokinesis.

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo.

Cell multiplication.

The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase.

Extension of chromatin accessibility by nuclear matrix attachment regions.

APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle.

Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.

Mechanisms of asymmetric cell division during animal development.

Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.

Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.

A rapid, quantitative and inexpensive method for detecting apoptosis by flow cytometry in transiently transfected cells.

Plasminogen-dependent and -independent proteolytic activity of murine endothelioma cells with targeted inactivation of fibrinolytic genes.

Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.

The five cleavage-stage (CS) histones of the sea urchin are encoded by a maternally expressed family of replacement histone genes: functional equivalence of the CS H1 and frog H1M (B4) proteins.

Canine tumour suppressor gene p53--mutation in a case of adenoma of circumanal glands.

Long-range interactions at the HO promoter.

Gene transfer mediated by influenza virus peptides: the role of peptide sequences.

Cohesins: chromosomal proteins that prevent premature separation of sister chromatids.

Dynamics of cell cycle regulators: artifact-free analysis by recultivation of cells synchronized by centrifugal elutriation.

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis.

The cytoskeleton in mRNA localization and cell differentiation.

Permeabilization of mammalian cells to proteins: poliovirus 2A(pro) as a probe to analyze entry of proteins into cells.

Essential functions of Pax-5 (BSAP) in pro-B cell development.

Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

Preparative two-dimensional gel electrophoresis of membrane proteins.

Endothelial cells transformed by polyomavirus middle-T oncogene: A model for hemangiomas and other vascular tumors.

Is the yeast anaphase promoting complex needed to prevent re-replication during G2 and M phases?

Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation.

Regulation of ES cell differentiation by functional and conformational modulation of p53.

Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system.

Cell-free tumor antigen peptide-based cancer vaccines.

Generation of effective cancer vaccines genetically engineered to secrete cytokines using adenovirus-enhanced transferrinfection (AVET).

Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis).

Cloning and functional characterization of the ornithokinin receptor. Recognition of the major kinin receptor antagonist, HOE140, as a full agonist.

Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.

Two-dimensional gel electrophoresis analysis of endovacuolar organelles.

Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene.

Stabilization of gene delivery systems by freeze-drying.

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs.

Two-dimensional mapping of the endogenous proteins of the rat hepatocyte Golgi complex cleared of proteins in transit.

The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human epsilon germline promoter.

Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.

Stem cell factor stimulates chicken osteoclast activity in vitro.

Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7.

In search of differentially expressed genes and proteins.

Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection.

PARP is important for genomic stability but dispensable in apoptosis.

The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors.

Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation.

CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo.

STAT5 involvement in the differentiation response of primary chicken myeloid progenitor cells to chicken myelomonocytic growth factor.

[Receptor mediated gene transfer in squamous epithelial carcinoma of the head-neck area].

Imprinted expression of the Igf2r gene depends on an intronic CpG island.

Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis.

Topogenesis of a nucleolar protein: determination of molecular segments directing nucleolar association.

Avian stem cell factor (SCF): production and characterization of the recombinant His-tagged SCF of chicken and its neutralizing antibody.

Avian erythropoiesis and erythroleukemia: towards understanding the role of the biomolecules involved.

Self renewal and differentiation in primary avian hematopoietic cells: an alternative to mammalian in vitro models?

The genetic revolution 1950-1996: An introduction

Gene therapy.

Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells.

Regulation and function of transcription factor GATA-1 during red blood cell differentiation.

Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma.

Cellular responses to adenovirus entry.

The complete DNA sequence and genomic organization of the avian adenovirus CELO.

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast.

Receptor-mediated gene delivery.

High primer concentration improves PCR amplification from random pools.

C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.

Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts.

Cloning and characterization of CpG islands of the human chromosome 1p36 region.

The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions.

Regulation of bone cell differentiation and bone remodelling by the c-Fos/AP-1 transcription factor.

Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models.

Development of a rapid means of estimating the haemoglobin F content of candidate fetal cells isolated from maternal blood using HPLC.

Endosomal fractions from viral K-ras-transformed MDCK cells reveal transformation specific changes on two-dimensional gel maps.

Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.

Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2.

EGT2 gene transcription is induced predominantly by Swi5 in early G1.

p72: a human nuclear DEAD box protein highly related to p68.

The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).

Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.

Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems.

Cell cycle regulation and erythroid differentiation.

Control of S phase

Viewpoint: putting the cell cycle in order.

A homage to Giardia.

At the heart of the budding yeast cell cycle.

Retinoblastoma protein. Another role rolls in.

Multiple roles for DNA methylation in gametic imprinting.

Hybrid proteins between Pseudomonas aeruginosa exotoxin A and poliovirus 2Apro cleave p220 in HeLa cells.

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.

Antiangiogenic therapy of transgenic mice impairs de novo tumor growth.

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast.

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

Normal brainstem auditory evoked potentials in Pax5-deficient mice despite morphologic alterations in the auditory midbrain region.

Transloading of tumor cells with foreign major histocompatibility complex class I peptide ligand: a novel general strategy for the generation of potent cancer vaccines.

The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.

The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters.

Tumor cells expressing a recall antigen are powerful cancer vaccines.

Adenovirus-enhanced receptor-mediated transferrinfection for the generation of tumor vaccines.

Depletion of naive T cells of the peripheral lymph nodes abrogates systemic antitumor protection conferred by IL-2 secreting cancer vaccines.

Cell cycle control of DNA replication in Saccharomyces cerevisiae.

Transgenic animals.

The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6.

Analysis of location and integrity of the human PITSLRE (p58CDC2L1) genes in neuroblastoma cell genomes. evidence against involvement in tumorigenesis.

Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus.

Adenovirus enhanced receptor mediated transferrinfection (AVET) applied to the generation of tumor vaccines.

Receptor-mediated gene delivery with synthetic virus-like particles.

Report of the second international workshop on human chromosome 1 mapping 1995.

TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast.

Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae.

Glycerol enhancement of ligand-polylysine/DNA transfection.

On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse.

Gametic imprinting in mammals.

Determination and regional assignment of grouped sets of microclones in chromosome 1pter-p35.

Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron.

In vitro growth of factor-dependent multipotential hematopoietic cells is induced by the nuclear oncoprotein v-Ski.

Transformation of erythroid progenitors by viral and cellular tyrosine kinases.

Avian hematopoietic cell culture: in vitro model systems to study oncogenic transformation of hematopoietic cells.

Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER.

v-rel protects transformed chicken bone marrow cells from apoptosis: A study with the conditional v-rel estrogen receptor fusion oncoprotein v-rel ER.

Cell proliferation and cell cycle progression are not impaired in fibroblasts and ES cells lacking c-Fos.

Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex.

The role of BSAP (Pax-5) in B-cell development.

Immediate effects of reversible HTLV-1 tax function: T-cell activation and apoptosis.

The entry mechanism of adenovirus and some solutions to the toxicity problems associated with adenovirus-augmented, receptor-mediated gene delivery.

Adenovirus-augmented, receptor-mediated gene delivery and some solutions to the common toxicity problems.

The adenovirus protease is required for virus entry into host cells.

Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.

DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.

Induction of the mitogen-activated p70 S6 kinase by adenovirus E1A.

Cell differentiation.

Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.

Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control.

Expression of the helix-loop-helix gene Id3 during murine embryonic development.

Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes.

Fos and bone cell development: lessons from a nuclear oncogene.

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.

Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast.

Cyclin-dependent kinase site-regulated signal-dependent nuclear localization of the SW15 yeast transcription factor in mammalian cells.

A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells.

Deregulated expression of PAX5 in medulloblastoma.

Thyroid hormone regulates stromelysin expression, protease secretion and the morphogenetic potential of normal polarized mammary epithelial cells.

Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination.

Tumor vaccines: effects and fate of IL-2 transfected murine melanoma cells in vivo.

Cell cycle-regulated transcription of the CLB2 gene is dependent on Mcm1 and a ternary complex factor.

Activation of HIV transcription by human foamy virus in transgenic mice.

Sequence of an exon of tumour suppressor p53 gene--a comparative study in domestic animals: mutation in a feline solid mammary carcinoma.

Mutations in tumour suppressor gene p53 in two feline fibrosarcomas.

Direct microdissection and microcloning of a translocation breakpoint region, t(1;11)(q42.2;q21), associated with schizophrenia.

Evolution of the cell cycle.

Characteristics of imprinted genes.

Activation of p70 S6 kinase and erk-encoded mitogen-activated protein kinases is resistant to high cyclic nucleotide levels in Swiss 3T3 fibroblasts.

Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors.

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

A versatile quick-prep of genomic DNA from gram-positive bacteria.

Spi-1 and mutant p53 regulate different aspects of the proliferation and differentiation control of primary erythroid progenitors.

Low affinity binding of interleukin-1 beta and intracellular signaling via NF-kappa B identify Fit-1 as a distant member of the interleukin-1 receptor family.

Cancer vaccines: the interleukin 2 dosage effect.

Fos is an essential component of the mammalian UV response.

Strain-dependent epithelial defects in mice lacking the EGF receptor.

Conservation of a maternal-specific methylation signal at the human IGF2R locus.

The gene coding for the B cell surface protein CD19 is localized on human chromosome 16p11.

Primary, self-renewing erythroid progenitors develop through activation of both tyrosine kinase and steroid hormone receptors.

Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection.

The PAX5 gene: a linkage and mutation analysis in candidate human primary immunodeficiencies.

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.

c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos.

Genomic imprinting: the parental connection.

Elicitation of a systemic and protective anti-melanoma immune response by an IL-2-based vaccine. Assessment of critical cellular and molecular parameters.

Rhinovirus-mediated endosomal release of transfection complexes.

Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.

Imprinting: a gamete's point of view.

Receptor-mediated gene delivery employing lectin-binding specificity.

An improved pair potential to recognize native protein folds.

Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.

Insights into erythroid differentiation obtained from studies on avian erythroblastosis virus.

Structure and expression of the chicken retinoblastoma gene.

Identification of AP-1-regulated genes.

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells.

NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.

Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus.

Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid.

Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells.

Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression.

Report and abstracts of the First International Workshop on Human Chromosome 1 Mapping 1994. Bethesda, Maryland, March 25-27, 1994.

Introduction: oncogenes and differentiation.

Characterization of a region-specific library of microclones in the vicinity of the Bcg and splotch loci on mouse chromosome 1.

High-level expression of various apolipoprotein(a) isoforms by "transferrinfection": the role of kringle IV sequences in the extracellular association with low-density lipoprotein.

Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling.

Thymocyte apoptosis induced by elevated endogenous corticosterone levels.

Two-dimensional gel mapping of small GTPases reveals transformation-specific changes during oncogenesis.

The H1A histone variant is an in vivo repressor of oocyte-type 5S gene transcription in Xenopus laevis embryos.

Expression of three- and four-repeat tau isoforms in mouse liver.

Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.

Oncogenic properties of the middle T antigens of polyomaviruses.

Cell cycle regulated transcription in yeast.

Electroporation of cosmid DNA into bacterial cells.

Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.

Embryonic germ cell lines and their derivation from mouse primordial germ cells.

Generation of alphoid DNA probes for fluorescence in situ hybridization (FISH) using the polymerase chain reaction.

Large-scale isolation of human 1p36-specific P1 clones and their use for fluorescence in situ hybridization.

FISH of Alu-PCR-amplified YAC clones and applications in tumor cytogenetics.

The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line epsilon transcription.

Generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells.

Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase.

An Egg-ocentric view of the cell cycle.

A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes.

Impressions of imprints.

Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment.

The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.

Oncogenes and epithelial cell transformation.

Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes.

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae.

Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro.

Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP.

Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities.

An intragenic TaqI RFLP at the PAX5 locus.

SSCP/SacI polymorphism in the PAX5 gene.

Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis.

Embryonic stem cell as a tool for analyzing mammalian hematopoietic development and disease.

Oncogenes in the study of endothelial cell growth and differentiation.

Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.

The analysis of disease-specific chromosomal rearrangements with microcloned DNA markers.

In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.

Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery: a new approach for immunotherapy of cancer.

Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes.

pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe.

Human foamy virus proteins accumulate in neurons and induce multinucleated giant cells in the brain of transgenic mice.

Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins.

Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.

Methylation and imprinting: from host defense to gene regulation?

A hormone-inducible v-rel estrogen receptor fusion as a means to transform early hematopoietic progenitor cells and to study their differentiation pathway.

A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.

Identification of a gene encoding a novel zinc finger protein in Saccharomyces cerevisiae.

Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.

Non-viral approaches to gene therapy.

Receptor-mediated transport of DNA into eukaryotic cells.

Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.

Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation.

DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro.

Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes.

Titin antibodies in myasthenia gravis: identification of a major immunogenic region of titin.

Osteoblasts are target cells for transformation in c-fos transgenic mice.

c-Fos oncogene expression in cartilage and bone tissues of transgenic and chimaeric mice.

Self-renewal and differentiation of normal avian erythroid progenitor cells: regulatory roles of the TGF alpha/c-ErbB and SCF/c-kit receptors.

c-jun is essential for normal mouse development and hepatogenesis.

Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 17.

A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase.

Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.

Kettin, a large modular protein in the Z-disc of insect muscles.

Transformation of chicken bone marrow cells by the v-ski oncogene.

Mutational analysis of the role of the carboxy-terminal region of the v-erbB protein in erythroid cell transformation.

Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway.

Yeast origin recognition complex is involved in DNA replication and transcriptional silencing.

Transcription factors important for starting the cell cycle in yeast.

Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12.

Regulating the HO endonuclease in yeast.

Control of the yeast cell cycle by the Cdc28 protein kinase.

Cell cycle. Dams and sluices.

Identification of pol-related gene products of human foamy virus.

The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization.

A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).

The estrogen receptor cooperates with the TGF alpha receptor (c-erbB) in regulation of chicken erythroid progenitor self-renewal.

CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.

Switching genes on at the START of the yeast cell cycle.

Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9.

Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.

SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast.

Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src.

Rescue of W-associated mast cell defects in W/Wv bone marrow cells by ectopic expression of normal and mutant epidermal growth factor receptors.

Exploring the pathogenic potential of polyoma middle T, c-fos and human foamy virus in transgenic mice.

Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors.

Tumour preventing genes in neuroblastoma.

Towards physical linkage map of the human chromosome 1p36 region.

Direct transcriptional stimulation of the ornithine decarboxylase gene by Fos in PC12 cells but not in fibroblasts.

Somatic gene therapy for cancer: the utility of transferrinfection in generating 'tumor vaccines'.

v-erbA.

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.

Expression of human foamy virus is differentially regulated during development in transgenic mice.

Human foamy virus: an underestimated neuropathogen?

Dominant and recessive molecular changes in neuroblastomas.

Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae.

Preparation, restriction and hybridization analysis of mammalian genomic DNA for pulsed-field gel electrophoresis.

Independent modulation of differentiation and proliferation in erythroid progenitors.

Molecular modeling on garuganin-I.

Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.

A chimaeric mouse model for autosomal-dominant polycystic kidney disease.

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

Identification of Fos target genes by the use of selective induction systems.

Angiogenic activity of the K-fgf/hst oncogene in neural transplants.

High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.

Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway.

High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes.

A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast.

Evolutionary conserved multiprotein complexes interact with the 3' untranslated region of histone transcripts.

Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.

cis and trans regulation of tissue-specific transcription.

Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.

Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.

Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.

The leukaemia oncogene v-erbA: a dominant negative version of ligand dependent transcription factors that regulates red cell differentiation?

Avian erythroblastosis: a model system to study oncogene co-operation in leukemia.

Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.

Dexamethasone selectively regulates the activity of enzymatic markers of cerebral endothelial cell lines.

Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene.

Characterization of early and late endocytic compartments of the transferrin cycle. Transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome.

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP.

The v-ski oncogene cooperates with the v-sea oncogene in erythroid transformation by blocking erythroid differentiation.

Histone H4 mRNA levels are down-regulated by 3' RNA processing during terminal differentiation of myoblasts.

SWI6 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae.

Mutations in the rel-homology domain alter the biochemical properties of v-rel and render it transformation defective in chicken embryo fibroblasts.