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See AllBacPROTACs mediate targeted protein degradation in bacteria.
Corresponding preprint Cell. 185(13):2338-2353.e18DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers.
Nat Genet. 54(5):613-624Latest publicatons
Scroll and browse the latest publications from the IMP. The most recent papers and pre-prints with IMP scientists as first- or corresponding authors.
See allDevelopmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers.
Mol Cell. 82(19):3598-3612.e7Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development.
Front Immunol. 13:979606A self-generated Toddler gradient guides mesodermal cell migration.
Sci Adv. 8(37):eadd2488DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations.
Science. 377(6612):eabj5502Single-cell analyses of axolotl telencephalon organization, neurogenesis, and regeneration.
Science. 377(6610):eabp9262Distinct features in fish Bouncer proteins determine sperm-egg compatibility
bioRxiv . 506233Structural basis of mRNA maturation: Time to put it together.
Curr Opin Struct Biol. 75:102431Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
J Exp Med. 219(9)Mechanism-based combination therapies for metastatic cancer.
Sci Transl Med. 14(655):eadd0887The specialist in regeneration-the Axolotl-a suitable model to study bone healing?
NPJ Regen Med. 7(1):35Top Events
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- Jeffrey Cheah Biomedical Centre
- Stein Aerts
- VIB Center for Brain and Disease Research