Browse the latest publications and preprints from the IMP. Here we list the most recent publications with IMP scientists as first- or corresponding authors in chronological order.
2022
The Sperm Protein Spaca6 is Essential for Fertilization in Zebrafish.
Corresponding preprint Front Cell Dev Biol. 9:8069822021
A self-generated Toddler gradient guides mesodermal cell migration
bioRxiv . 2021.12.16.472981Targeting CD56 with an antibody-drug conjugate in Merkel cell carcinoma.
Br J Dermatol.AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature. 599(7885):491-496The cellular and signaling dynamics of salamander limb regeneration.
Curr Opin Cell Biol. 73:117-123Cohesin mediates DNA loop extrusion by a "swing and clamp" mechanism.
Cell. 184(21):5448-5464.e22Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia.
Cancer Discov. 11(11):2868-2883A molecular network of conserved factors keeps ribosomes dormant in the egg
bioRxiv . 2021.11.03.467131Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing
bioRxiv . 2021.11.03.467109miR-1 sustains muscle physiology by controlling V-ATPase complex assembly.
Sci Adv. 7(42):eabh1434Positional Memory in Vertebrate Regeneration: A Century's Insights from the Salamander Limb.
Cold Spring Harb Perspect Biol.The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization.
Corresponding preprint Proc Natl Acad Sci U S A. 118(39)McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Corresponding preprint Elife. 10HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat Chem Biol.The Fertilization Enigma: How Sperm and Egg Fuse.
Annu Rev Cell Dev Biol.Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
Nature Cancer . 2:693–708Genome folding through loop extrusion by SMC complexes.
Nat Rev Mol Cell Biol. 22(7):445-464Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation.
Sci Immunol. 6(61)Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition.
PLoS Genet. 17(2):e1009390Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration.
Elife. 10E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP
bioRxiv. 2021.05.10.443411Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics.
medRxiv. 2021.01.19.21250079