Publications | IMP Scientific Papers | Research Institute of Molecular Pathology (IMP)

The IMP publishes 60 to 90 scientific papers in international peer-review journals every year. This evidence for the productivity and high scientific standard of the IMP is listed here in full – a directory of all scientific publications by IMP scientists since the establishment of the institute, organised by years and research groups.

2017

Andergassen, D., Dotter, CP., Wenzel, D., Sigl, V., Bammer, PC., Muckenhuber, M., Mayer, D., Kulinski, TM., Theussl, HC., Penninger, JM., Bock, C., Barlow, DP., Pauler, FM., Hudson, QJ. (2017) Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression. Elife. 6

Arnold, CD., Zabidi, MA., Pagani, M., Rath, M., Schernhuber, K., Kazmar, T., Stark, A. (2017) Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution. Nat Biotechnol. 35(2):136-144

Beckham, KS., Ciccarelli, L., Bunduc, CM., Mertens, HD., Ummels, R., Lugmayr, W., Mayr, J., Rettel, M., Savitski, MM., Svergun, DI., Bitter, W., Wilmanns, M., Marlovits, TC., Parret, AH., Houben, EN. (2017) Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis. Nat Microbiol. 2:17047

Breuss, MW., Hansen, AH., Landler, L., Keays, DA. (2017) Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. Behav Brain Res. 323:47-55

Breuss, MW., Leca, I., Gstrein, T., Hansen, AH., Keays, DA. (2017) Tubulins and brain development - The origins of functional specification. Mol Cell Neurosci.

Breuss, MW., Nguyen, T., Srivatsan, A., Leca, I., Tian, G., Fritz, T., Hansen, AH., Musaev, D., McEvoy-Venneri, J., James, KN., Rosti, RO., Scott, E., Tan, U., Kolodner, RD., Cowan, NJ., Keays, DA., Gleeson, JG. (2017) Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 26(2):258-269

Busslinger, GA., Stocsits, RR., van der Lelij, P., Axelsson, E., Tedeschi, A., Galjart, N., Peters, JM. (2017) Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl. Nature. 544(7651):503-507

Doblas, VG., Smakowska-Luzan, E., Fujita, S., Alassimone, J., Barberon, M., Madalinski, M., Belkhadir, Y., Geldner, N. (2017) Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor. Science. 355(6322):280-284

Franz, A., Shlyueva, D., Brunner, E., Stark, A., Basler, K. (2017) Probing the canonicity of the Wnt/Wingless signaling pathway. PLoS Genet. 13(4):e1006700

Greiner, G., Witzeneder, N., Berger, A., Schmetterer, K., Eisenwort, G., Schiefer, AI., Roos, S., Popow-Kraupp, T., Müllauer, L., Zuber, J., Sexl, V., Kenner, L., Sperr, WR., Valent, P., Mayerhofer, M., Hoermann, G. (2017) CCL2 is a KIT D816V-dependent modulator of the bone marrow microenvironment in systemic mastocytosis. Blood. 129(3):371-382

Hogg, SJ., Vervoort, SJ., Deswal, S., Ott, CJ., Li, J., Cluse, LA., Beavis, PA., Darcy, PK., Martin, BP., Spencer, A., Traunbauer, AK., Sadovnik, I., Bauer, K., Valent, P., Bradner, JE., Zuber, J., Shortt, J., Johnstone, RW. (2017) BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1. Cell Rep. 18(9):2162-2174

Housden, BE., Muhar, M., Gemberling, M., Gersbach, CA., Stainier, DY., Seydoux, G., Mohr, SE., Zuber, J., Perrimon, N. (2017) Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nat Rev Genet. 18(1):24-40

Ishihara, K., Ranga, A., Lutolf, MP., Tanaka, EM., Meinhardt, A. (2017) Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells. Methods Mol Biol. 1597:43-55

Jang, H., Levy, S., Flavell, SW., Mende, F., Latham, R., Zimmer, M., Bargmann, CI. (2017) Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 114(7):E1263-E1272

Kreslavsky, T., Vilagos, B., Tagoh, H., Poliakova, DK., Schwickert, TA., Wöhner, M., Jaritz, M., Weiss, S., Taneja, R., Rossner, MJ., Busslinger, M. (2017) Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells. Nat Immunol. 18(4):442-455

Pajenda, S., Mechtler, K., Wagner, L. (2017) Urinary neprilysin in the critically ill patient. BMC Nephrol. 18(1):172

Pelossof, R., Fairchild, L., Huang, CH., Widmer, C., Sreedharan, VT., Sinha, N., Lai, DY., Guan, Y., Premsrirut, PK., Tschaharganeh, DF., Hoffmann, T., Thapar, V., Xiang, Q., Garippa, RJ., Rätsch, G., Zuber, J., Lowe, SW., Leslie, CS., Fellmann, C. (2017) Prediction of potent shRNAs with a sequential classification algorithm. Nat Biotechnol. 35(4):350-353

Reiter, F., Wienerroither, S., Stark, A. (2017) Combinatorial function of transcription factors and cofactors. Curr Opin Genet Dev. 43:73-81

Riley, NM., Hebert, AS., Dürnberger, G., Stanek, F., Mechtler, K., Westphall, MS., Coon, JJ. (2017) Phosphoproteomics with Activated Ion Electron Transfer Dissociation. Anal Chem.

Shodhan, A., Novatchkova, M., Loidl, J. (2017) BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena. Chromosome Res.

Smeenk, L., Fischer, M., Jurado, S., Jaritz, M., Azaryan, A., Werner, B., Roth, M., Zuber, J., Stanulla, M., den Boer, ML., Mullighan, CG., Strehl, S., Busslinger, M. (2017) Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia. EMBO J. 36(6):718-735

Valerio, DG., Xu, H., Chen, CW., Hoshii, T., Eisold, ME., Delaney, C., Cusan, M., Deshpande, AJ., Huang, CH., Lujambio, A., Zheng, YG., Zuber, J., Pandita, TK., Lowe, SW., Armstrong, SA. (2017) Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis. Cancer Res. 77(7):1753-1762

Willems, S., Bouyssié, D., David, M., Locard-Paulet, M., Mechtler, K., Schwämmle, V., Uszkoreit, J., Vaudel, M., Dorfer, V. (2017) Proceedings of the EuBIC Winter School 2017. J Proteomics.

2016

Adams, WC., Chen, YH., Kratchmarov, R., Yen, B., Nish, SA., Lin, WW., Rothman, NJ., Luchsinger, LL., Klein, U., Busslinger, M., Rathmell, JC., Snoeck, HW., Reiner, SL. (2016) Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Cell Rep. 17(12):3142-3152

Ali, AK., Oh, JS., Vivier, E., Busslinger, M., Lee, SH. (2016) NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation. J Immunol. 196(4):1753-67

Asaoka, T., Almagro, J., Ehrhardt, C., Tsai, I., Schleiffer, A., Deszcz, L., Junttila, S., Ringrose, L., Mechtler, K., Kavirayani, A., Gyenesei, A., Hofmann, K., Duchek, P., Rittinger, K., Ikeda, F. (2016) Linear ubiquitination by LUBEL has a role in Drosophila heat stress response. EMBO Rep. 17(11):1624-1640

Baker, A., Gregory, GP., Verbrugge, I., Kats, L., Hilton, JJ., Vidacs, E., Lee, EM., Lock, RB., Zuber, J., Shortt, J., Johnstone, RW. (2016) The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia. Cancer Res. 76(5):1158-69

Bigenzahn, JW., Fauster, A., Rebsamen, M., Kandasamy, RK., Scorzoni, S., Vladimer, GI., Müller, AC., Gstaiger, M., Zuber, J., Bennett, KL., Superti-Furga, G. (2016) An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client. Mol Cell Proteomics. 15(3):1139-50

Breuss, M., Fritz, T., Gstrein, T., Chan, K., Ushakova, L., Yu, N., Vonberg, FW., Werner, B., Elling, U., Keays, DA. (2016) Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis. Development. 143(7):1126-33

Broix, L., Jagline, H., L Ivanova, E., Schmucker, S., Drouot, N., Clayton-Smith, J., Pagnamenta, AT., Metcalfe, KA., Isidor, B., Louvier, UW., Poduri, A., Taylor, JC., Tilly, P., Poirier, K., Saillour, Y., Lebrun, N., Stemmelen, T., Rudolf, G., Muraca, G., Saintpierre, B., Elmorjani, A., Moïse, M., Weirauch, NB., Guerrini, R., Boland, A., Olaso, R., Masson, C., Tripathy, R., Keays, D., Beldjord, C., Nguyen, L., Godin, J., Kini, U., Nischké, P., Deleuze, JF., Bahi-Buisson, N., Sumara, I., Hinckelmann, MV., Chelly, J. (2016) Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 48(11):1349-1358

Brown, NG., VanderLinden, R., Watson, ER., Weissmann, F., Ordureau, A., Wu, KP., Zhang, W., Yu, S., Mercredi, PY., Harrison, JS., Davidson, IF., Qiao, R., Lu, Y., Dube, P., Brunner, MR., Grace, CR., Miller, DJ., Haselbach, D., Jarvis, MA., Yamaguchi, M., Yanishevski, D., Petzold, G., Sidhu, SS., Kuhlman, B., Kirschner, MW., Harper, JW., Peters, JM., Stark, H., Schulman, BA. (2016) Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell. 165(6):1440-53

Cabrera-Quio, LE., Herberg, S., Pauli, A. (2016) Decoding sORF translation - from small proteins to gene regulation. RNA Biol. 13(11):1051-1059

Camurdanoglu, BZ., Hrovat, C., Dürnberger, G., Madalinski, M., Mechtler, K., Herbst, R. (2016) Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop. Sci Rep. 6:33583

Davidson, IF., Goetz, D., Zaczek, MP., Molodtsov, MI., Huis In 't Veld, PJ., Weissmann, F., Litos, G., Cisneros, DA., Ocampo-Hafalla, M., Ladurner, R., Uhlmann, F., Vaziri, A., Peters, JM. (2016) Rapid movement and transcriptional re-localization of human cohesin on DNA. EMBO J. 35(24):2671-2685

Delconte, RB., Shi, W., Sathe, P., Ushiki, T., Seillet, C., Minnich, M., Kolesnik, TB., Rankin, LC., Mielke, LA., Zhang, JG., Busslinger, M., Smyth, MJ., Hutchinson, DS., Nutt, SL., Nicholson, SE., Alexander, WS., Corcoran, LM., Vivier, E., Belz, GT., Carotta, S., Huntington, ND. (2016) The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15. Immunity. 44(1):103-15

Dietsche, T., Tesfazgi Mebrhatu, M., Brunner, MJ., Abrusci, P., Yan, J., Franz-Wachtel, M., Schärfe, C., Zilkenat, S., Grin, I., Galán, JE., Kohlbacher, O., Lea, S., Macek, B., Marlovits, TC., Robinson, CV., Wagner, S. (2016) Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus. PLoS Pathog. 12(12):e1006071

Drexel, T., Mahofsky, K., Latham, R., Zimmer, M., Cochella, L. (2016) Neuron type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans. Genes Dev. 30(18):2042-2047

Gallego, LD., Ghodgaonkar Steger, M., Polyansky, AA., Schubert, T., Zagrovic, B., Zheng, N., Clausen, T., Herzog, F., Köhler, A. (2016) Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1. Proc Natl Acad Sci U S A. 113(38):10553-8

Ghisi, M., Kats, L., Masson, F., Li, J., Kratina, T., Vidacs, E., Gilan, O., Doyle, MA., Newbold, A., Bolden, JE., Fairfax, KA., de Graaf, CA., Firth, M., Zuber, J., Dickins, RA., Corcoran, LM., Dawson, MA., Belz, GT., Johnstone, RW. (2016) Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia. Cancer Cell. 30(1):59-74

Haas, MA., Ngo, L., Li, SS., Schleich, S., Qu, Z., Vanyai, HK., Cullen, HD., Cardona-Alberich, A., Gladwyn-Ng, IE., Pagnamenta, AT., Taylor, JC., Stewart, H., Kini, U., Duncan, KE., Teleman, AA., Keays, DA., Heng, JI. (2016) De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. Cell Rep. 15(10):2251-65

Hempel, A., Pagnamenta, AT., Blyth, M., Mansour, S., McConnell, V., Kou, I., Ikegawa, S., Tsurusaki, Y., Matsumoto, N., Lo-Castro, A., Plessis, G., Albrecht, B., Battaglia, A., Taylor, JC., Howard, MF., Keays, D., Sohal, AS., Kühl, SJ., Kini, U., McNeill, A. (2016) Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome. J Med Genet. 53(3):152-62

Heuck, A., Schitter-Sollner, S., Suskiewicz, MJ., Kurzbauer, R., Kley, J., Schleiffer, A., Rombaut, P., Herzog, F., Clausen, T. (2016) Structural basis for the disaggregase activity and regulation of Hsp104. Elife. 5

Hons, MT., Huis In 't Veld, PJ., Kaesler, J., Rombaut, P., Schleiffer, A., Herzog, F., Stark, H., Peters, JM. (2016) Topology and structure of an engineered human cohesin complex bound to Pds5B. Nat Commun. 7:12523

Houben, A., Kostanova-Poliakova, D., Weissenböck, M., Graf, J., Teufel, S., von der Mark, K., Hartmann, C. (2016) β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 143(20):3826-3838

Huis In 't Veld, PJ., Jeganathan, S., Petrovic, A., Singh, P., John, J., Krenn, V., Weissmann, F., Bange, T., Musacchio, A. (2016) Molecular basis of outer kinetochore assembly on CENP-T. Elife. 5

Hums, I., Riedl, J., Mende, F., Kato, S., Kaplan, HS., Latham, R., Sonntag, M., Traunmüller, L., Zimmer, M. (2016) Regulation of two motor patterns enables the gradual adjustment of locomotion strategy in Caenorhabditis elegans. Elife. 5

Isokane, M., Walter, T., Mahen, R., Nijmeijer, B., Hériché, JK., Miura, K., Maffini, S., Ivanov, MP., Kitajima, TS., Peters, JM., Ellenberg, J. (2016) ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores. J Cell Biol. 212(6):647-59

Jarvis, MA., Brown, NG., Watson, ER., VanderLinden, R., Schulman, BA., Peters, JM. (2016) Measuring APC/C-Dependent Ubiquitylation In Vitro. Methods Mol Biol. 1342:287-303

Kaufmann, T., Kukolj, E., Brachner, A., Beltzung, E., Bruno, M., Kostrhon, S., Opravil, S., Hudecz, O., Mechtler, K., Warren, G., Slade, D. (2016) SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 129(24):4607-4621

Kiermaier, E., Moussion, C., Veldkamp, CT., Gerardy-Schahn, R., de Vries, I., Williams, LG., Chaffee, GR., Phillips, AJ., Freiberger, F., Imre, R., Taleski, D., Payne, RJ., Braun, A., Förster, R., Mechtler, K., Mühlenhoff, M., Volkman, BF., Sixt, M. (2016) Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 351(6269):186-90

Kim, JS., He, X., Orr, B., Wutz, G., Hill, V., Peters, JM., Compton, DA., Waldman, T. (2016) Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 12(2):e1005865

Kollmann, K., Heller, G., Schneckenleithner, C., Warsch, W., Scheicher, R., Ott, RG., Schäfer, M., Fajmann, S., Schlederer, M., Schiefer, AI., Reichart, U., Mayerhofer, M., Hoeller, C., Zöchbauer-Müller, S., Kerjaschki, D., Bock, C., Kenner, L., Hoefler, G., Freissmuth, M., Green, AR., Moriggl, R., Busslinger, M., Malumbres, M., Sexl, V. (2016) A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis. Cancer Cell. 30(2):359-360

Ladurner, R., Kreidl, E., Ivanov, MP., Ekker, H., Idarraga-Amado, MH., Busslinger, GA., Wutz, G., Cisneros, DA., Peters, JM. (2016) Sororin actively maintains sister chromatid cohesion. EMBO J. 35(6):635-53

Lange, L., Pagnamenta, AT., Lise, S., Clasper, S., Stewart, H., Akha, ES., Quaghebeur, G., Knight, SJ., Keays, DA., Taylor, JC., Kini, U. (2016) A de novo frameshift in HNRNPK causing a Kabuki-like syndrome with nodular heterotopia. Clin Genet. 90(3):258-62

Leong, YA., Chen, Y., Ong, HS., Wu, D., Man, K., Deleage, C., Minnich, M., Meckiff, BJ., Wei, Y., Hou, Z., Zotos, D., Fenix, KA., Atnerkar, A., Preston, S., Chipman, JG., Beilman, GJ., Allison, CC., Sun, L., Wang, P., Xu, J., Toe, JG., Lu, HK., Tao, Y., Palendira, U., Dent, AL., Landay, AL., Pellegrini, M., Comerford, I., McColl, SR., Schacker, TW., Long, HM., Estes, JD., Busslinger, M., Belz, GT., Lewin, SR., Kallies, A., Yu, D. (2016) CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nat Immunol. 17(10):1187-96

Mackay, LK., Minnich, M., Kragten, NA., Liao, Y., Nota, B., Seillet, C., Zaid, A., Man, K., Preston, S., Freestone, D., Braun, A., Wynne-Jones, E., Behr, FM., Stark, R., Pellicci, DG., Godfrey, DI., Belz, GT., Pellegrini, M., Gebhardt, T., Busslinger, M., Shi, W., Carbone, FR., van Lier, RA., Kallies, A., van Gisbergen, KP. (2016) Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science. 352(6284):459-63

Meshcheryakova, A., Svoboda, M., Tahir, A., Köfeler, HC., Triebl, A., Mungenast, F., Heinze, G., Gerner, C., Zimmermann, P., Jaritz, M., Mechtcheriakova, D. (2016) Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach. Oncotarget. 7(16):22295-323

Minnich, M., Tagoh, H., Bönelt, P., Axelsson, E., Fischer, M., Cebolla, B., Tarakhovsky, A., Nutt, SL., Jaritz, M., Busslinger, M. (2016) Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation. Nat Immunol. 17(3):331-43

Mlecnik, B., Bindea, G., Kirilovsky, A., Angell, HK., Obenauf, AC., Tosolini, M., Church, SE., Maby, P., Vasaturo, A., Angelova, M., Fredriksen, T., Mauger, S., Waldner, M., Berger, A., Speicher, MR., Pagès, F., Valge-Archer, V., Galon, J. (2016) The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis. Sci Transl Med. 8(327):327ra26

Molodtsov, MI., Mieck, C., Dobbelaere, J., Dammermann, A., Westermann, S., Vaziri, A. (2016) A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation. Cell. 167(2):539-552.e14

Moreno, E., McGaughran, A., Rödelsperger, C., Zimmer, M., Sommer, RJ. (2016) Oxygen-induced social behaviours in Pristionchus pacificus have a distinct evolutionary history and genetic regulation from Caenorhabditis elegans. Proc Biol Sci. 283(1825):20152263

Muerdter, F., Stark, A. (2016) Gene Regulation: Activation through Space. Curr Biol. 26(19):R895-R898

Nowacka, JD., Baumgartner, C., Pelorosso, C., Roth, M., Zuber, J., Baccarini, M. (2016) MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 7(49):80113-80130

Pagnamenta, AT., Howard, MF., Knight, SJ., Keays, DA., Quaghebeur, G., Taylor, JC., Kini, U. (2016) Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities. Clin Case Rep. 4(10):952-956

Pang, SH., Minnich, M., Gangatirkar, P., Zheng, Z., Ebert, A., Song, G., Dickins, RA., Corcoran, LM., Mullighan, CG., Busslinger, M., Huntington, ND., Nutt, SL., Carotta, S. (2016) PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia. Leukemia. 30(6):1375-87

Panser, K., Tirian, L., Schulze, F., Villalba, S., Jefferis, GS., Bühler, K., Straw, AD. (2016) Automatic Segmentation of Drosophila Neural Compartments Using GAL4 Expression Data Reveals Novel Visual Pathways. Curr Biol. 26(15):1943-54

Pasquarella, A., Ebert, A., Pereira de Almeida, G., Hinterberger, M., Kazerani, M., Nuber, A., Ellwart, J., Klein, L., Busslinger, M., Schotta, G. (2016) Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells. Development. 143(10):1788-99

Pekgöz Altunkaya, G., Malvezzi, F., Demianova, Z., Zimniak, T., Litos, G., Weissmann, F., Mechtler, K., Herzog, F., Westermann, S. (2016) CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore. Curr Biol. 26(17):2370-8

Polakova, S., Molnarova, L., Hyppa, RW., Benko, Z., Misova, I., Schleiffer, A., Smith, GR., Gregan, J. (2016) Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation. PLoS Genet. 12(6):e1006102

Prevedel, R., Verhoef, AJ., Pernía-Andrade, AJ., Weisenburger, S., Huang, BS., Nöbauer, T., Fernández, A., Delcour, JE., Golshani, P., Baltuska, A., Vaziri, A. (2016) Fast volumetric calcium imaging across multiple cortical layers using sculpted light. Nat Methods. 13(12):1021-1028

Qiao, R., Weissmann, F., Yamaguchi, M., Brown, NG., VanderLinden, R., Imre, R., Jarvis, MA., Brunner, MR., Davidson, IF., Litos, G., Haselbach, D., Mechtler, K., Stark, H., Schulman, BA., Peters, JM. (2016) Mechanism of APC/CCDC20 activation by mitotic phosphorylation. Proc Natl Acad Sci U S A. 113(19):E2570-8

Rampler, E., Stranzl, T., Orban-Nemeth, Z., Hollenstein, DM., Hudecz, O., Schlögelhofer, P., Mechtler, K. (2016) Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1". J Proteome Res. 15(5):1732

Reddien, PW., Tanaka, EM. (2016) Editorial overview: Cell reprogramming, regeneration and repair. Curr Opin Genet Dev. 40:iv-vi

Reimão-Pinto, MM., Manzenreither, RA., Burkard, TR., Sledz, P., Jinek, M., Mechtler, K., Ameres, SL. (2016) Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila. EMBO J. 35(22):2417-2434

Rickels, R., Hu, D., Collings, CK., Woodfin, AR., Piunti, A., Mohan, M., Herz, HM., Kvon, E., Shilatifard, A. (2016) An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Mol Cell. 63(2):318-28

Sdelci, S., Lardeau, CH., Tallant, C., Klepsch, F., Klaiber, B., Bennett, J., Rathert, P., Schuster, M., Penz, T., Fedorov, O., Superti-Furga, G., Bock, C., Zuber, J., Huber, KV., Knapp, S., Müller, S., Kubicek, S. (2016) Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Nat Chem Biol. 12(7):504-10

Shlyueva, D., Meireles-Filho, AC., Pagani, M., Stark, A. (2016) Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation. PLoS One. 11(8):e0161997

Sigl, V., Owusu-Boaitey, K., Joshi, PA., Kavirayani, A., Wirnsberger, G., Novatchkova, M., Kozieradzki, I., Schramek, D., Edokobi, N., Hersl, J., Sampson, A., Odai-Afotey, A., Lazaro, C., Gonzalez-Suarez, E., Pujana, MA., Cimba, F., Heyn, H., Vidal, E., Cruickshank, J., Berman, H., Sarao, R., Ticevic, M., Uribesalgo, I., Tortola, L., Rao, S., Tan, Y., Pfeiler, G., Lee, EY., Bago-Horvath, Z., Kenner, L., Popper, H., Singer, C., Khokha, R., Jones, LP., Penninger, JM. (2016) RANKL/RANK control Brca1 mutation-driven mammary tumors. Cell Res. 26(7):761-74

Smaldone, G., Pirone, L., Pedone, E., Marlovits, T., Vitagliano, L., Ciccarelli, L. (2016) The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states. FEBS Lett. 590(11):1663-71

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Köcher, T. (2011) Comment on 'Jobs for the boys'. EMBO Rep. 12(6):488

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Medvedovic, J., Ebert, A., Tagoh, H., Busslinger, M. (2011) Pax5: a master regulator of B cell development and leukemogenesis. Adv Immunol. 111:179-206

Merdanovic, M., Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) Protein quality control in the bacterial periplasm. Annu Rev Microbiol. 65:149-68

Nacu, E., Tanaka, EM. (2011) Limb regeneration: a new development? Annu Rev Cell Dev Biol. 27:409-40

Neumüller, RA., Richter, C., Fischer, A., Novatchkova, M., Neumüller, KG., Knoblich, JA. (2011) Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93

Ng, K., Daigle, N., Bancaud, A., Ohhata, T., Humphreys, P., Walker, R., Ellenberg, J., Wutz, A. (2011) A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells. Mol Biol Cell. 22(14):2634-45

Pappu, KS., Morey, M., Nern, A., Spitzweck, B., Dickson, BJ., Zipursky, SL. (2011) Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development. Proc Natl Acad Sci U S A. 108(18):7571-6

Pichler, P., Köcher, T., Holzmann, J., Möhring, T., Ammerer, G., Mechtler, K. (2011) Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell. Anal Chem. 83(4):1469-74

Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, CL., Lührmann, R., Söll, D., Martinez, J. (2011) HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science. 331(6018):760-4

Qin, H., Suzuki, K., Nakata, M., Chikuma, S., Izumi, N., Huong, le T., Maruya, M., Fagarasan, S., Busslinger, M., Honjo, T., Nagaoka, H. (2011) Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One. 6(12):e29141

Resch, GP., Brandstetter, M., Pickl-Herk, AM., Königsmaier, L., Wonesch, VI., Urban, E. (2011) Immersion freezing of biological specimens: rationale, principles, and instrumentation. Cold Spring Harb Protoc. 2011(7):778-82

Sampaio, JL., Gerl, MJ., Klose, C., Ejsing, CS., Beug, H., Simons, K., Shevchenko, A. (2011) Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A. 108(5):1903-7

Sawa, J., Malet, H., Krojer, T., Canellas, F., Ehrmann, M., Clausen, T. (2011) Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J Biol Chem. 286(35):30680-90

Schönbauer, C., Distler, J., Jährling, N., Radolf, M., Dodt, HU., Frasch, M., Schnorrer, F. (2011) Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479(7373):406-9

Schraidt, O., Marlovits, TC. (2011) Three-dimensional model of Salmonella's needle complex at subnanometer resolution. Science. 331(6021):1192-5

Stöger-Pollach, M., Treiber, CD., Resch, GP., Keays, DA., Ennen, I. (2011) EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 42(5):456-60

Takada, Y., Gresh, L., Bozec, A., Ikeda, E., Kamiya, K., Watanabe, M., Kobayashi, K., Asano, K., Toyama, Y., Wagner, EF., Matsuo, K. (2011) Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-1. Oncogene. 30(36):3821-32

Tanaka, EM., Reddien, PW. (2011) The cellular basis for animal regeneration. Dev Cell. 21(1):172-85

Taschler, U., Radner, FP., Heier, C., Schreiber, R., Schweiger, M., Schoiswohl, G., Preiss-Landl, K., Jaeger, D., Reiter, B., Koefeler, HC., Wojciechowski, J., Theussl, C., Penninger, JM., Lass, A., Haemmerle, G., Zechner, R., Zimmermann, R. (2011) Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem. 286(20):17467-77

Taus, T., Köcher, T., Pichler, P., Paschke, C., Schmidt, A., Henrich, C., Mechtler, K. (2011) Universal and confident phosphorylation site localization using phosphoRS. J Proteome Res. 10(12):5354-62

Truebestein, L., Tennstaedt, A., Mönig, T., Krojer, T., Canellas, F., Kaiser, M., Clausen, T., Ehrmann, M. (2011) Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat Struct Mol Biol. 18(3):386-8

von Philipsborn, AC., Liu, T., Yu, JY., Masser, C., Bidaye, SS., Dickson, BJ. (2011) Neuronal control of Drosophila courtship song. Neuron. 69(3):509-22

York, AG., Ghitani, A., Vaziri, A., Davidson, MW., Shroff, H. (2011) Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes. Nat Methods. 8(4):327-33

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2010

Agrelo, R., Wutz, A. (2010) ConteXt of change--X inactivation and disease. EMBO Mol Med. 2(1):6-15

Agrelo, R., Wutz, A. (2010) X inactivation and disease. Semin Cell Dev Biol. 21(2):194-200

Alpert, AJ., Petritis, K., Kangas, L., Smith, RD., Mechtler, K., Mitulović, G., Mohammed, S., Heck, AJ. (2010) Peptide orientation affects selectivity in ion-exchange chromatography. Anal Chem. 82(12):5253-9

Antos, CL., Tanaka, EM. (2010) Vertebrates that regenerate as models for guiding stem cels. Adv Exp Med Biol. 695:184-214

Baudrimont, A., Penkner, A., Woglar, A., Machacek, T., Wegrostek, C., Gloggnitzer, J., Fridkin, A., Klein, F., Gruenbaum, Y., Pasierbek, P., Jantsch, V. (2010) Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans. PLoS Genet. 6(11):e1001219

Baumann, CL., Aspalter, IM., Sharif, O., Pichlmair, A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, KL., Colinge, J., Knapp, S., Superti-Furga, G. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med. 207(12):2689-701

Berg, DA., Kirkham, M., Beljajeva, A., Knapp, D., Habermann, B., Ryge, J., Tanaka, EM., Simon, A. (2010) Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain. Development. 137(24):4127-34

Bouchard, M., de Caprona, D., Busslinger, M., Xu, P., Fritzsch, B. (2010) Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol. 10:89

Braglia, P., Heindl, K., Schleiffer, A., Martinez, J., Proudfoot, NJ. (2010) Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I. EMBO Rep. 11(10):758-64

Braun, A., Breuss, M., Salzer, MC., Flint, J., Cowan, NJ., Keays, DA. (2010) Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 86(5):819-22; author reply 822-3

Cachero, S., Ostrovsky, AD., Yu, JY., Dickson, BJ., Jefferis, GS. (2010) Sexual dimorphism in the fly brain. Curr Biol. 20(18):1589-601

Csiszar, A., Vogelsang, E., Beug, H., Leptin, M. (2010) A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol. 30(8):2017-27

Dickson, BJ., Zou, Y. (2010) Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol. 2(8):a002055

El-Kasaby, A., Just, H., Malle, E., Stolt-Bergner, PC., Sitte, HH., Freissmuth, M., Kudlacek, O. (2010) Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem. 285(50):39201-10

Elsayad, K., Heinze, KG. (2010) Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks Physical Review A. 81(5)

Elsayad, K., Heinze, KG. (2010) Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films Proc. SPIE. 7757:77573L

Elsayad, K., Urich, A., Unterrainer, K., Heinze, KG. (2010) Fast near-field imaging of spectrally broad sources using layered metallic structures Proc. SPIE. 7757:77573M

Eskeland, R., Leeb, M., Grimes, GR., Kress, C., Boyle, S., Sproul, D., Gilbert, N., Fan, Y., Skoultchi, AI., Wutz, A., Bickmore, WA. (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 38(3):452-64

Feng, W., Yonezawa, M., Ye, J., Jenuwein, T., Grummt, I. (2010) PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol. 17(4):445-50

Friedbichler, K., Kerenyi, MA., Kovacic, B., Li, G., Hoelbl, A., Yahiaoui, S., Sexl, V., Müllner, EW., Fajmann, S., Cerny-Reiterer, S., Valent, P., Beug, H., Gouilleux, F., Bunting, KD., Moriggl, R. (2010) Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood. 116(9):1548-58

Fuchs, A., Inthal, A., Herrmann, D., Cheng, S., Nakatomi, M., Peters, H., Neubüser, A. (2010) Regulation of Tbx22 during facial and palatal development. Dev Dyn. 239(11):2860-74

Fujimori, S., Novak, H., Weissenböck, M., Jussila, M., Gonçalves, A., Zeller, R., Galloway, J., Thesleff, I., Hartmann, C. (2010) Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 348(1):97-106

Galkin, VE., Schmied, WH., Schraidt, O., Marlovits, TC., Egelman, EH. (2010) The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system. J Mol Biol. 396(5):1392-7

Gin, E., Tanaka, EM., Brusch, L. (2010) A model for cyst lumen expansion and size regulation via fluid secretion. J Theor Biol. 264(3):1077-88

Grausenburger, R., Bilic, I., Boucheron, N., Zupkovitz, G., El-Housseiny, L., Tschismarov, R., Zhang, Y., Rembold, M., Gaisberger, M., Hartl, A., Epstein, MM., Matthias, P., Seiser, C., Ellmeier, W. (2010) Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol. 185(6):3489-97

Haider, S., Wagner, M., Schmid, MC., Sixt, BS., Christian, JG., Häcker, G., Pichler, P., Mechtler, K., Müller, A., Baranyi, C., Toenshoff, ER., Montanaro, J., Horn, M. (2010) Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae. Mol Microbiol. 77(3):687-700

Hasenbein, S., Meltzer, M., Hauske, P., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2010) Conversion of a regulatory into a degradative protease. J Mol Biol. 397(4):957-66

Haubner, BJ., Neely, GG., Voelkl, JG., Damilano, F., Kuba, K., Imai, Y., Komnenovic, V., Mayr, A., Pachinger, O., Hirsch, E., Penninger, JM., Metzler, B. (2010) PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway. PLoS One. 5(2):e9350

Heinz, E., Pichler, P., Heinz, C., Op den Camp, HJ., Toenshoff, ER., Ammerer, G., Mechtler, K., Wagner, M., Horn, M. (2010) Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies. Proteomics. 10(24):4363-76

Herrmann, D., Ferrer-Vaquer, A., Lahsnig, C., Firnberg, N., Leibbrandt, A., Neubüser, A. (2010) Expression and regulation of ANTXR1 in the chick embryo. Dev Dyn. 239(2):680-7

Hnisz, D., Majer, O., Frohner, IE., Komnenovic, V., Kuchler, K. (2010) The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog. 6(5):e1000889

Hoelbl, A., Schuster, C., Kovacic, B., Zhu, B., Wickre, M., Hoelzl, MA., Fajmann, S., Grebien, F., Warsch, W., Stengl, G., Hennighausen, L., Poli, V., Beug, H., Moriggl, R., Sexl, V. (2010) Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med. 2(3):98-110

Huang, J., Dorsey, J., Chuikov, S., Pérez-Burgos, L., Zhang, X., Jenuwein, T., Reinberg, D., Berger, SL. (2010) G9a and Glp methylate lysine 373 in the tumor suppressor p53. J Biol Chem. 285(13):9636-41

Huber, MA., Maier, HJ., Alacakaptan, M., Wiedemann, E., Braunger, J., Boehmelt, G., Madwed, JB., Young, ER., Marshall, DR., Pehamberger, H., Wirth, T., Kraut, N., Beug, H. (2010) BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. Genes Cancer. 1(2):101-14

Hutchins, JR., Toyoda, Y., Hegemann, B., Poser, I., Hériché, JK., Sykora, MM., Augsburg, M., Hudecz, O., Buschhorn, BA., Bulkescher, J., Conrad, C., Comartin, D., Schleiffer, A., Sarov, M., Pozniakovsky, A., Slabicki, MM., Schloissnig, S., Steinmacher, I., Leuschner, M., Ssykor, A., Lawo, S., Pelletier, L., Stark, H., Nasmyth, K., Ellenberg, J., Durbin, R., Buchholz, F., Mechtler, K., Hyman, AA., Peters, JM. (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 328(5978):593-9

Ishizaki, K., Suzuki, K., Mito, T., Tanaka, EM., Sato, S. (2010) Morphologic, functional, and occlusal characterization of mandibular lateral displacement malocclusion. Am J Orthod Dentofacial Orthop. 137(4):454.e1-9; discussion 454-5

Johnson, BA., Kahler, DJ., Baban, B., Chandler, PR., Kang, B., Shimoda, M., Koni, PA., Pihkala, J., Vilagos, B., Busslinger, M., Munn, DH., Mellor, AL. (2010) B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A. 107(23):10644-8

Karginov, FV., Cheloufi, S., Chong, MM., Stark, A., Smith, AD., Hannon, GJ. (2010) Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases. Mol Cell. 38(6):781-8

Katis, VL., Lipp, JJ., Imre, R., Bogdanova, A., Okaz, E., Habermann, B., Mechtler, K., Nasmyth, K., Zachariae, W. (2010) Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Dev Cell. 18(3):397-409

Keays, DA., Cleak, J., Huang, GJ., Edwards, A., Braun, A., Treiber, CD., Pidsley, R., Flint, J. (2010) The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus. Dev Neurosci. 32(4):268-77

Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2010) Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway. J Virol. 84(8):3984-92

Kim, YJ., Bartalska, K., Audsley, N., Yamanaka, N., Yapici, N., Lee, JY., Kim, YC., Markovic, M., Isaac, E., Tanaka, Y., Dickson, BJ. (2010) MIPs are ancestral ligands for the sex peptide receptor. Proc Natl Acad Sci U S A. 107(14):6520-5

Krojer, T., Sawa, J., Huber, R., Clausen, T. (2010) HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol. 17(7):844-52

Kuçi, S., Kuçi, Z., Kreyenberg, H., Deak, E., Pütsch, K., Huenecke, S., Amara, C., Koller, S., Rettinger, E., Grez, M., Koehl, U., Latifi-Pupovci, H., Henschler, R., Tonn, T., von Laer, D., Klingebiel, T., Bader, P. (2010) CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties. Haematologica. 95(4):651-9

Lampert, F., Hornung, P., Westermann, S. (2010) The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex. J Cell Biol. 189(4):641-9

Leeb, M., Pasini, D., Novatchkova, M., Jaritz, M., Helin, K., Wutz, A. (2010) Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev. 24(3):265-76

Leeb, M., Wutz, A. (2010) Mechanistic concepts in X inactivation underlying dosage compensation in mammals. Heredity (Edinb). 105(1):64-70

Leitner, A., Sturm, M., Hudecz, O., Mazanek, M., Smått, JH., Lindén, M., Lindner, W., Mechtler, K. (2010) Probing the phosphoproteome of HeLa cells using nanocast metal oxide microspheres for phosphopeptide enrichment. Anal Chem. 82(7):2726-33

Lukaszewicz, A., Howard-Till, RA., Novatchkova, M., Mochizuki, K., Loidl, J. (2010) MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena. Chromosoma. 119(5):505-18

Lyashenko, N., Weissenböck, M., Sharir, A., Erben, RG., Minami, Y., Hartmann, C. (2010) Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn. 239(8):2266-77

Mach-Aigner, AR., Grosstessner-Hain, K., Poças-Fonseca, MJ., Mechtler, K., Mach, RL. (2010) From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach. BMC Genomics. 11:644

Maier HJ., Wirth T., Beug H. (2010) Epithelial-Mesenchymal Transition in Pancreatic Carcinoma Cancers . 2(4):2058-2083

Maier, HJ., Schmidt-Strassburger, U., Huber, MA., Wiedemann, EM., Beug, H., Wirth, T. (2010) NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett. 295(2):214-28

Majewski, IJ., Ritchie, ME., Phipson, B., Corbin, J., Pakusch, M., Ebert, A., Busslinger, M., Koseki, H., Hu, Y., Smyth, GK., Alexander, WS., Hilton, DJ., Blewitt, ME. (2010) Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood. 116(5):731-9

Malin, S., McManus, S., Busslinger, M. (2010) STAT5 in B cell development and leukemia. Curr Opin Immunol. 22(2):168-76

Malin, S., McManus, S., Cobaleda, C., Novatchkova, M., Delogu, A., Bouillet, P., Strasser, A., Busslinger, M. (2010) Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development. Nat Immunol. 11(2):171-9

Marlovits, TC., Stebbins, CE. (2010) Type III secretion systems shape up as they ship out. Curr Opin Microbiol. 13(1):47-52

Marth, K., Novatchkova, M., Focke-Tejkl, M., Jenisch, S., Jäger, S., Kabelitz, D., Valenta, R. (2010) Tracing antigen signatures in the human IgE repertoire. Mol Immunol. 47(14):2323-9

Maschler, S., Gebeshuber, CA., Wiedemann, EM., Alacakaptan, M., Schreiber, M., Custic, I., Beug, H. (2010) Annexin A1 attenuates EMT and metastatic potential in breast cancer. EMBO Mol Med. 2(10):401-14

Mazanek, M., Roitinger, E., Hudecz, O., Hutchins, JR., Hegemann, B., Mitulović, G., Taus, T., Stingl, C., Peters, JM., Mechtler, K. (2010) A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes. J Chromatogr B Analyt Technol Biomed Life Sci. 878(5-6):515-24

Molatore, S., Kiermaier, E., Jung, CB., Lee, M., Pulz, E., Höfler, H., Atkinson, MJ., Pellegata, NS. (2010) Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors. Mol Cancer. 9:116

Morandell, S., Grosstessner-Hain, K., Roitinger, E., Hudecz, O., Lindhorst, T., Teis, D., Wrulich, OA., Mazanek, M., Taus, T., Ueberall, F., Mechtler, K., Huber, LA. (2010) QIKS--Quantitative identification of kinase substrates. Proteomics. 10(10):2015-25

Mujezinovic, N., Schneider, G., Wildpaner, M., Mechtler, K., Eisenhaber, F. (2010) Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction. BMC Genomics. 11 Suppl 1:S13

Murchison, EP., Tovar, C., Hsu, A., Bender, HS., Kheradpour, P., Rebbeck, CA., Obendorf, D., Conlan, C., Bahlo, M., Blizzard, CA., Pyecroft, S., Kreiss, A., Kellis, M., Stark, A., Harkins, TT., Marshall Graves, JA., Woods, GM., Hannon, GJ., Papenfuss, AT. (2010) The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science. 327(5961):84-7

Neely, GG., Hess, A., Costigan, M., Keene, AC., Goulas, S., Langeslag, M., Griffin, RS., Belfer, I., Dai, F., Smith, SB., Diatchenko, L., Gupta, V., Xia, CP., Amann, S., Kreitz, S., Heindl-Erdmann, C., Wolz, S., Ly, CV., Arora, S., Sarangi, R., Dan, D., Novatchkova, M., Rosenzweig, M., Gibson, DG., Truong, D., Schramek, D., Zoranovic, T., Cronin, SJ., Angjeli, B., Brune, K., Dietzl, G., Maixner, W., Meixner, A., Thomas, W., Pospisilik, JA., Alenius, M., Kress, M., Subramaniam, S., Garrity, PA., Bellen, HJ., Woolf, CJ., Penninger, JM. (2010) A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 143(4):628-38

Neely, GG., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmén, L., Gupta, V., Arora, S., Sarangi, R., Dan, D., Fujisawa, S., Usami, T., Xia, CP., Keene, AC., Alayari, NN., Yamakawa, H., Elling, U., Berger, C., Novatchkova, M., Koglgruber, R., Fukuda, K., Nishina, H., Isobe, M., Pospisilik, JA., Imai, Y., Pfeufer, A., Hicks, AA., Pramstaller, PP., Subramaniam, S., Kimura, A., Ocorr, K., Bodmer, R., Penninger, JM. (2010) A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell. 141(1):142-53

Neumann, B., Walter, T., Hériché, JK., Bulkescher, J., Erfle, H., Conrad, C., Rogers, P., Poser, I., Held, M., Liebel, U., Cetin, C., Sieckmann, F., Pau, G., Kabbe, R., Wünsche, A., Satagopam, V., Schmitz, MH., Chapuis, C., Gerlich, DW., Schneider, R., Eils, R., Huber, W., Peters, JM., Hyman, AA., Durbin, R., Pepperkok, R., Ellenberg, J. (2010) Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature. 464(7289):721-7

Neumüller, KG., Elsayad, K., Reisecker, JM., Waxham, MN., Heinze, KG. (2010) Photounbinding of calmodulin from a family of CaM binding peptides. PLoS One. 5(11):e14050

Nishiyama, T., Ladurner, R., Schmitz, J., Kreidl, E., Schleiffer, A., Bhaskara, V., Bando, M., Shirahige, K., Hyman, AA., Mechtler, K., Peters, JM. (2010) Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell. 143(5):737-49

Olivieri, D., Sykora, MM., Sachidanandam, R., Mechtler, K., Brennecke, J. (2010) An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila. EMBO J. 29(19):3301-17

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2009

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Hutchins, JR., Moore, WJ., Clarke, PR. (2009) Dynamic localisation of Ran GTPase during the cell cycle. BMC Cell Biol. 10:66

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Khattak, S., Richter, T., Tanaka, EM. (2009) Generation of transgenic axolotls (Ambystoma mexicanum). Cold Spring Harb Protoc. 2009(8):pdb.prot5264

Khattak, S., Tanaka, EM. (2009) Axolotl (Ambystoma mexicanum) in vitro fertilization. Cold Spring Harb Protoc. 2009(8):pdb.prot5263

Kiermaier, E., Woehrer, S., Peng, Y., Mechtler, K., Westermann, S. (2009) A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast. Nat Cell Biol. 11(9):1109-15

Köcher, T., Pichler, P., Schutzbier, M., Stingl, C., Kaul, A., Teucher, N., Hasenfuss, G., Penninger, JM., Mechtler, K. (2009) High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all. J Proteome Res. 8(10):4743-52

Kragl, M., Tanaka, EM. (2009) Axolotl (Ambystoma mexicanum) limb and tail amputation. Cold Spring Harb Protoc. 2009(8):pdb.prot5267

Kragl, M., Tanaka, EM. (2009) Grafting axolotl (Ambystoma mexicanum) limb skin and cartilage from GFP+ donors to normal hosts. Cold Spring Harb Protoc. 2009(8):pdb.prot5266

Kudo, NR., Anger, M., Peters, AH., Stemmann, O., Theussl, HC., Helmhart, W., Kudo, H., Heyting, C., Nasmyth, K. (2009) Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci. 122(Pt 15):2686-98

Lahsnig, C., Mikula, M., Petz, M., Zulehner, G., Schneller, D., van Zijl, F., Huber, H., Csiszar, A., Beug, H., Mikulits, W. (2009) ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. Oncogene. 28(5):638-50

Lawo, S., Bashkurov, M., Mullin, M., Ferreria, MG., Kittler, R., Habermann, B., Tagliaferro, A., Poser, I., Hutchins, JR., Hegemann, B., Pinchev, D., Buchholz, F., Peters, JM., Hyman, AA., Gingras, AC., Pelletier, L. (2009) HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol. 19(10):816-26

Leeb, M., Steffen, PA., Wutz, A. (2009) X chromosome inactivation sparked by non-coding RNAs. RNA Biol. 6(2):94-9

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Meireles-Filho, AC., Stark, A. (2009) Comparative genomics of gene regulation-conservation and divergence of cis-regulatory information. Curr Opin Genet Dev. 19(6):565-70

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Mietton, F., Sengupta, AK., Molla, A., Picchi, G., Barral, S., Heliot, L., Grange, T., Wutz, A., Dimitrov, S. (2009) Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome. Mol Cell Biol. 29(1):150-6

Mitulović, G., Stingl, C., Steinmacher, I., Hudecz, O., Hutchins, JR., Peters, JM., Mechtler, K. (2009) Preventing carryover of peptides and proteins in nano LC-MS separations. Anal Chem. 81(14):5955-60

Müller, KP., Erdel, F., Caudron-Herger, M., Marth, C., Fodor, BD., Richter, M., Scaranaro, M., Beaudouin, J., Wachsmuth, M., Rippe, K. (2009) Multiscale analysis of dynamics and interactions of heterochromatin protein 1 by fluorescence fluctuation microscopy. Biophys J. 97(11):2876-85

Müller, MQ., de Koning, LJ., Schmidt, A., Ihling, C., Syha, Y., Rau, O., Mechtler, K., Schubert-Zsilavecz, M., Sinz, A. (2009) An innovative method to study target protein-drug interactions by mass spectrometry. J Med Chem. 52(9):2875-9

Mummery-Widmer, JL., Yamazaki, M., Stoeger, T., Novatchkova, M., Bhalerao, S., Chen, D., Dietzl, G., Dickson, BJ., Knoblich, JA. (2009) Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458(7241):987-92

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