Publications

E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP

Gaze mechanisms enabling the detection of faint stars in the night sky.

PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.

The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.

The expression, localisation and interactome of pigeon CRY2.

Systematic refinement of gene annotations by parsing mRNA 3' end sequencing datasets.

The sperm protein Spaca6 is essential for fertilization in zebrafish

Cdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle.

Down-regulation of A20 promotes immune escape of lung adenocarcinomas.

Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition.

Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation.

Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users.

Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration.

Genome folding through loop extrusion by SMC complexes.

The Fertilization Enigma: How Sperm and Egg Fuse.

MS Amanda 2.0: Advancements in the standalone implementation.

Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters.

Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue.

The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization.

Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.

HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.

Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect.

Maternally-inherited anti-sense piRNAs antagonize transposon expression in teleost embryos

Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma

A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.

McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.

Cardioids reveal self-organizing principles of human cardiogenesis.

Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.

MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.

Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics.

Concepts and functions of small RNA pathways in C. elegans.

Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly.

A molecular network of conserved factors keeps ribosomes dormant in the egg

Fibroblast dedifferentiation as a determinant of successful regeneration.

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells.

Toward whole tissue imaging of axolotl regeneration.

Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein-Protein Interaction Networks in Vivo.

Giant lungfish genome elucidates the conquest of land by vertebrates.

Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation.

BacPROTACs mediate targeted protein degradation in bacteria

Sperm membrane proteins DCST1 and DCST2 are required for the sperm-egg fusion process in mice and fish

Gene and transgenics nomenclature for the laboratory axolotl-Ambystoma mexicanum.

RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.

Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation.

How DNA loop extrusion mediated by cohesin enables V(D)J recombination.

DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations

A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation.

MS Annika: A New Cross-Linking Search Engine.

A new society for regenerative biologists.

Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.

The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains.

The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci.

Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.

Insights into gene regulation: From regulatory genomic elements to DNA-protein and protein-protein interactions.

Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia.

Ultrasensitive NanoLC-MS of Subnanogram Protein Samples Using Second Generation Micropillar Array LC Technology with Orbitrap Exploris 480 and FAIMS PRO.

Self-organized cell migration across scales - from single cell movement to tissue formation.

Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.

Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.

Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex.

GSK3-mediated phosphorylation of DEK3 regulates chromatin accessibility and stress tolerance in Arabidopsis.

Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics.

Cellular Control of Protein Turnover via the Modification of the Amino Terminus.

SCON - A Short Conditional intrON for conditional knockout with one-step zygote injection

Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq.

Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism.

MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.

Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.

Native Mass Spectrometry Can Effectively Predict PROTAC Efficacy.

A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes.

Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse.

Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.

Combinatorial Action of Temporally Segregated Transcription Factors.

MicroRNAs: From Mechanism to Organism.

Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegans.

A human tissue screen identifies a regulator of ER secretion as a brain-size determinant.

Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.

Unsupervised learning of control signals and their encodings in Caenorhabditis elegans whole-brain recordings.

Author Correction: Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signalling.

Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction.

NMD is required for timely cell fate transitions by fine-tuning gene expression and controlling translation

A Data Structure for Real-Time Aggregation Queries of Big Brain Networks.

Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.

Species-specific mechanisms during fertilization.

Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion.

The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor.

Nested Neuronal Dynamics Orchestrate a Behavioral Hierarchy across Timescales.

Brain-wide representations of ongoing behavior: a universal principle?

The amygdala instructs insular feedback for affective learning.

A rapid, highly sensitive and open-access SARS-CoV-2 detection assay for laboratory and home testing

SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells.

HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.

DigiTAG-a RNA Sequencing Approach to Analyze Transcriptomes of Rare Cell Populations in Drosophila melanogaster.

The H3 histone chaperone NASPSIM3 escorts CenH3 in Arabidopsis.

A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.

LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma.

Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level.

Repression of the B cell identity factor Pax5 is not required for plasma cell development.

Neuronal circuits and the magnetic sense: central questions.

Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming.

AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes.

Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides.

Activation by substoichiometric inhibition.

Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration.

Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.

Conformation of sister chromatids in the replicated human genome.

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

Why (and how) we should publish negative data.

A high sensitivity ZENK monoclonal antibody to map neuronal activity in Aves.

Introducing www.axolotl-omics.org - an integrated -omics data portal for the axolotl research community.

Identification of ALK in Thinness.

A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity.

Calcium modulates the domain flexibility and function of an α-actinin similar to the ancestral α-actinin.

ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.

Stress peptides sensitize fear circuitry to promote passive coping.

Structure of the human core transcription-export complex reveals a hub for multivalent interactions.

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis.

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.

A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis.

Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes.

Quantifying the heterogeneity of macromolecular machines by mass photometry.

Oral and Palatal Dentition of Axolotl Arises From a Common Tooth-Competent Zone Along the Ecto-Endodermal Boundary.

A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress.

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers.

STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.

ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL.

Structure-function analysis of microRNA 3'-end trimming by Nibbler.

Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells.

The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop.

The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.

The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.

Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells.

Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.

Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts.

DNA loop extrusion by human cohesin.

apQuant: Accurate Label-Free Quantification by Quality Filtering.

Cryptic activation of an Irf8 enhancer governs cDC1 fate specification.

Publisher Correction: Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).

Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signalling

BrainTrawler: A visual analytics framework for iterative exploration of heterogeneous big brain data

Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins.

Allies or Enemies-The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment.

Transcriptional cofactors display specificity for distinct types of core promoters.

Estrogen Signaling Drives Ciliogenesis in Human Endometrial Organoids.

Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.

Functional-genetic approaches to understanding drug response and resistance.

Shaping Striated Muscles with Ubiquitin Proteasome System in Health and Disease.

Absolute quantification of cohesin, CTCF and their regulators in human cells.

Evolution of neuronal anatomy and circuitry in two highly divergent nematode species.

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination.

A Comparative Perspective on Brain Regeneration in Amphibians and Teleost Fish.

No evidence for a magnetite-based magnetoreceptor in the lagena of pigeons.

Broad applicability of a streamlined ethyl cinnamate-based clearing procedure.

Sequencing cell-type-specific transcriptomes with SLAM-ITseq.

Publisher Correction: Sequencing cell-type-specific transcriptomes with SLAM-ITseq.

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.

A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.

Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets.

STARR-seq and UMI-STARR-seq: Assessing Enhancer Activities for Genome-Wide-, High-, and Low-Complexity Candidate Libraries.

The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells.

All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia.

A Putative Mechanism for Magnetoreception by Electromagnetic Induction in the Pigeon Inner Ear.

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1.

Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes.

Tinbergen's challenge for the neuroscience of behavior.

Structural Basis of Nuclear pre-mRNA Splicing: Lessons from Yeast.

A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription.

Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.

Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.

Structural analysis of urinary light chains and proteomic analysis of hyaline tubular casts in light chain associated kidney disorders.

A role for miR-132 in learned safety.

Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism.

Ikaros prevents autoimmunity by controlling anergy and Toll-like receptor signaling in B cells.

MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.

Self-organization of parS centromeres by the ParB CTP hydrolase.

Improved Sensitivity in Low-Input Proteomics Using Micropillar Array-Based Chromatography.

Optimized Fragmentation Improves the Identification of Peptides Cross-Linked by MS-Cleavable Reagents.

Structure of McsB, a protein kinase for regulated arginine phosphorylation.

Spectral recording of gene expression history by fluorescent timer protein.

Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.

Imaging the Emergence of Behavior.

Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute.

Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.

Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.

Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy.

Human blood vessel organoids as a model of diabetic vasculopathy.

A novel approach to immunoapheresis of C3a/C3 and proteomic identification of associates.

N-terminal β-strand underpins biochemical specialization of an ATG8 isoform.

Pooled Generation of Lentiviral Tetracycline-Regulated microRNA Embedded Short Hairpin RNA Libraries.

Cell-type specific sequencing of microRNAs from complex animal tissues.

A high-throughput method to identify trans-activation domains within transcription factor sequences.

Epigenetic regulation of brain region-specific microglia clearance activity.

CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.

Human tripartite motif protein 52 is required for cell context-dependent proliferation.

Experimental and computational framework for a dynamic protein atlas of human cell division.

Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.

Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation.

The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.

CharmeRT: Boosting Peptide Identifications by Chimeric Spectra Identification and Retention Time Prediction.

PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search.

The IAP family member BRUCE regulates autophagosome-lysosome fusion.

Lidocaine is a nocebo treatment for trigeminally mediated magnetic orientation in birds.

Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).

Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation.

Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.

Predicting functional neuroanatomical maps from fusing brain networks with genetic information.

Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration.

The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML.

Dorsal tegmental dopamine neurons gate associative learning of fear.

Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.

A new era of proactive melanoma therapy: hit hard, hit early.

Eukaryotic core promoters and the functional basis of transcription initiation.

Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta.

Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.

UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.

The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization.

Improved Genome Assembly and Annotation for the Rock Pigeon (Columba livia).

The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.

Sensorimotor integration in Caenorhabditis elegans: a reappraisal towards dynamic and distributed computations.

Sensorimotor Integration for Decision Making: How the Worm Steers.

Control of B-1a cell development by instructive BCR signaling.

Cryptochrome: The magnetosensor with a sinister side?

Comment on "Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans".

Ectopic otoconial formation in the lagena of the pigeon inner ear.

SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting.

Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.

Senescence-associated reprogramming promotes cancer stemness.

CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis.

Resolving systematic errors in widely used enhancer activity assays in human cells.

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis.

The axolotl genome and the evolution of key tissue formation regulators.

Author Correction: The axolotl genome and the evolution of key tissue formation regulators.

Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration.

Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.

Reply to 'Defining distance restraints in HADDOCK'.

Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.

Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis.

Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.

Prespliceosome structure provides insights into spliceosome assembly and regulation.

Behavioral Assays to Study Oxygen and Carbon Dioxide Sensing in Caenorhabditis elegans.

A programmable platform for sub-second multichemical dynamic stimulation and neuronal functional imaging in C. elegans.

Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.

Necroptosis microenvironment directs lineage commitment in liver cancer.

Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy.

High-speed volumetric imaging of neuronal activity in freely moving rodents.

Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents.

Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans.

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

An extracellular network of Arabidopsis leucine-rich repeat receptor kinases.

Analysis of PNGase F-Resistant N-Glycopeptides Using SugarQb for Proteome Discoverer 2.1 Reveals Cryptic Substrate Specificities.

Dynamics of sister chromatid resolution during cell cycle progression.

The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity.

Regenerating tissues.

Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.

A Guide to Emerging Technologies for Large-Scale and Whole-Brain Optical Imaging of Neuronal Activity.

Expressing Multi-subunit Complexes Using biGBac.

Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop.

TCEA1 regulates the proliferative potential of mouse myeloid cells.

Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.

An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries.

A framework for understanding the roles of miRNAs in animal development.

Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.

Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution.

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition.

Tubulins and brain development - The origins of functional specification.

Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability.

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl.

Promoting transcription over long distances.

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations.

Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor.

A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.

Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration.

Probing the canonicity of the Wnt/Wingless signaling pathway.

Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives.

A mechanism of cohesin-dependent loop extrusion organizes zygotic genome architecture.

CCL2 is a KIT D816V-dependent modulator of the bone marrow microenvironment in systemic mastocytosis.

Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.

Thiol-linked alkylation of RNA to assess expression dynamics.

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.

Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.

Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells.

Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia.

Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans.

Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells.

STAT3 Regulation of Citrate Synthase Is Essential during the Initiation of Lymphocyte Cell Growth.

CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.

A global brain state underlies C. elegans sleep behavior.

Is magnetogenetics the new optogenetics?

Subcellular analysis of pigeon hair cells implicates vesicular trafficking in cuticulosome formation and maintenance.

Video rate volumetric Ca2+ imaging across cortex using seeded iterative demixing (SID) microscopy.

Magnetoreception-A sense without a receptor.

Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.

A right-handed signalling pathway drives heart looping in vertebrates.

The crystal structure of Deg9 reveals a novel octameric-type HtrA protease.

Urinary neprilysin in the critically ill patient.

Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.

R Loops in the Regulation of Antibody Gene Diversification.

Prediction of potent shRNAs with a sequential classification algorithm.

RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.

Combinatorial function of transcription factors and cofactors.

Phosphoproteomics with Activated Ion Electron Transfer Dissociation.

Nodal patterning without Lefty inhibitory feedback is functional but fragile.

Non-model model organisms.

DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.

A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist Tetrahymena.

BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena.

Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia.

Control of type III protein secretion using a minimal genetic system.

Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.

Virtual reality for freely moving animals.

A vital sugar code for ricin toxicity.

Salamander spinal cord regeneration: The ultimate positive control in vertebrate spinal cord regeneration.

Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.

Proceedings of the EuBIC Winter School 2017.

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.

NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation.

Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.

The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia.

An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client.

Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.

Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.

Decoding sORF translation - from small proteins to gene regulation.

MuSK Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop.

Rapid movement and transcriptional re-localization of human cohesin on DNA.

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus.

Neuron type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans.

Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.

De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation.

Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome.

Structural basis for the disaggregase activity and regulation of Hsp104.

Topology and structure of an engineered human cohesin complex bound to Pds5B.

β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis.

Molecular basis of outer kinetochore assembly on CENP-T.

Regulation of two motor patterns enables the gradual adjustment of locomotion strategy in Caenorhabditis elegans.

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.

Measuring APC/C-Dependent Ubiquitylation In Vitro.

SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition.

Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis.

Sororin actively maintains sister chromatid cohesion.

A de novo frameshift in HNRNPK causing a Kabuki-like syndrome with nodular heterotopia.

CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.

Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach.

Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.

The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.

A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation.

Oxygen-induced social behaviours in Pristionchus pacificus have a distinct evolutionary history and genetic regulation from Caenorhabditis elegans.

Gene Regulation: Activation through Space.

MEK1 is required for the development of NRAS-driven leukemia.

Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities.

PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.

Automatic Segmentation of Drosophila Neural Compartments Using GAL4 Expression Data Reveals Novel Visual Pathways.

Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells.

CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore.

Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation.

Fast volumetric calcium imaging across multiple cortical layers using sculpted light.

Mechanism of APC/CCDC20 activation by mitotic phosphorylation.

Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1".

Editorial overview: Cell reprogramming, regeneration and repair.

Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.

An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS.

Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.

Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation.

RANKL/RANK control Brca1 mutation- .

The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states.

RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2.

Chemical Biology Interrogates Protein Arginine Phosphorylation.

Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response.

Direct detection of a single photon by humans.

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.

Adaptive and Background-Aware GAL4 Expression Enhancement of Co-registered Confocal Microscopy Images.

Arginine phosphorylation marks proteins for degradation by a Clp protease.

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes.

DNA Replication Origins in Immunoglobulin Switch Regions Regulate Class Switch Recombination in an R-Loop-Dependent Manner.

A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.

C. elegans Body Cavity Neurons Are Homeostatic Sensors that Integrate Fluctuations in Oxygen Availability and Internal Nutrient Reserves.

Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development.

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.

Regulatory Enhancer-Core-Promoter Communication via Transcription Factors and Cofactors.

Anion-exchange chromatography of phosphopeptides: weak anion exchange versus strong anion exchange and anion-exchange chromatography versus electrostatic repulsion-hydrophilic interaction chromatography.

An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies MLKL as an HSP90 client.

The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons.

Direct and indirect targeting of MYC to treat acute myeloid leukemia.

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space.

The histone chaperone CAF-1 safeguards somatic cell identity.

Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals.

Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement.

Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci.

No evidence for intracellular magnetite in putative vertebrate magnetoreceptors identified by magnetic screening.

Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.

Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.

Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.

Coordinating the human looks.

G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.

Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation.

Mutations in PIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies.

Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.

Global brain dynamics embed the motor command sequence of Caenorhabditis elegans.

Transgenesis in axolotl (Ambystoma mexicanum).

Synaptic Orb2A Bridges Memory Acquisition and Late Memory Consolidation in Drosophila.

Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.

Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.

Predicting the Dynamics of Network Connectivity in the Neocortex.

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.

Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3.

STARR-seq - principles and applications.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.

The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.

3DSpectra: A 3-dimensional quantification algorithm for LC-MS labeled profile data.

Pillars Article: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999. 401: 556-562.

MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells.

Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis.

Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish.

Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation.

Determinants of amyloid fibril degradation by the PDZ protease HTRA1.

Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1.

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.

High-efficiency electroporation of the spinal cord in larval axolotl.

Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration.

Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.

Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia.

Optimizing and extending light-sculpting microscopy for fast functional imaging in neuroscience.

Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia.

CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.

The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.

Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia.

Burst muscle performance predicts the speed, acceleration, and turning performance of Anna's hummingbirds.

Laser-induced acoustic desorption of natural and functionalized biochromophores.

The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle.

Transcriptional regulators form diverse groups with context-dependent regulatory functions.

Visualizing KcsA conformational changes upon ion binding by infrared spectroscopy and atomistic modeling.

Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.

Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.

Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome.

Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction.

The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.

Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation.

Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.

Modeling human development in 3D culture.

Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution.

Measuring the functional organization of the neocortex at large and small scales.

FlyMAD: rapid thermogenetic control of neuronal activity in freely walking Drosophila.

Neuronal control of Drosophila walking direction.

Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.

Microtubules and neurodevelopmental disease: the movers and the makers.

Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.

Preclinical efficacy of MEK inhibition in Nras-mutant AML.

Epigenetic control of immunity.

Central amygdala PKC-δ(+) neurons mediate the influence of multiple anorexigenic signals.

Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation.

Mathematical modeling of regenerative processes.

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.

Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum.

Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.

Automated image-based tracking and its application in ecology.

ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.

RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.

Is salamander hindlimb regeneration similar to that of the forelimb? Anatomical and morphogenetic analysis of hindlimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative and developmental studies.

Is salamander limb regeneration really perfect? Anatomical and morphogenetic analysis of forelimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative, developmental, and evolutionary studies.

Development of fore- and hindlimb muscles in GFP-transgenic axolotls: morphogenesis, the tetrapod bauplan, and new insights on the forelimb-hindlimb enigma.

MS Amanda, a universal identification algorithm optimized for high accuracy tandem mass spectra.

Global analysis of muscle-specific kinase signaling by quantitative phosphoproteomics.

CRISPR-mediated genomic deletion of Sox2 in the axolotl shows a requirement in spinal cord neural stem cell amplification during tail regeneration.

Ascending SAG neurons control sexual receptivity of Drosophila females.

Asymmetric processing of visual motion for simultaneous object and background responses.

Flying Drosophila stabilize their vision-based velocity controller by sensing wind with their antennae.

Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells.

Myosin chaperones.

Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids.

A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.

Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation.

CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.

Characterization of a DNA exit gate in the human cohesin ring.

The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells.

Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.

Optimized axolotl (Ambystoma mexicanum) husbandry, breeding, metamorphosis, transgenesis and tamoxifen-mediated recombination.

Germline Transgenic Methods for Tracking Cells and Testing Gene Function during Regeneration in the Axolotl.

Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.

Development and performance evaluation of an ultralow flow nanoliquid chromatography-tandem mass spectrometry set-up.

Genome-scale functional characterization of Drosophila developmental enhancers in vivo.

Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation.

Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.

"Uno, nessuno e centomila": the different faces of the budding yeast kinetochore.

Neural circuit components of the Drosophila OFF motion vision pathway.

3D reconstitution of the patterned neural tube from embryonic stem cells.

cis-regulatory requirements for tissue-specific programs of the circadian clock.

The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes.

Alternative 3' UTR selection controls PAR-5 homeostasis and cell polarity in C. elegans embryos.

Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation.

Electron tomography and simulation of baculovirus actin comet tails support a tethered filament model of pathogen propulsion.

Genomics: Hiding in plain sight.

TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons.

Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins.

Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.

Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy.

B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.

Structure of a pathogenic type 3 secretion system in action.

A dual role for autophagy in a murine model of lung cancer.

A conserved role for Snail as a potentiator of active transcription.

NDST1 missense mutations in autosomal recessive intellectual disability.

In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.

Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species.

H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress.

Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.

Stage-specific control of early B cell development by the transcription factor Ikaros.

Differential requirement for Nfil3 during NK cell development.

Transcriptional enhancers: from properties to genome-wide predictions.

Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin.

Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of Tetrahymena.

Reverse Engineering Animal Vision with Virtual Reality and Genetics.

Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism.

Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.

BRD4: a BET(ter) target for the treatment of AML?

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs.

Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.

A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.

qcML: an exchange format for quality control metrics from mass spectrometry experiments.

Epigenetic targeting of activation-induced cytidine deaminase.

Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.

Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.

Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features.

Cellular and molecular basis of decision-making.

Development of siRNA payloads to target KRAS-mutant cancer.

Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.

Genome-wide quantitative enhancer activity maps identified by STARR-seq.

Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain.

Identification of transcription factor binding sites from ChIP-seq data at high resolution.

A multiplicative reinforcement learning model capturing learning dynamics and interindividual variability in mice.

Multiple mechanisms contribute to centriole separation in C. elegans.

Discriminating external and internal causes for heading changes in freely flying Drosophila.

Periventricular heterotopia in 6q terminal deletion syndrome: role of the C6orf70 gene.

Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.

Control of antigen receptor diversity through spatial regulation of V(D)J recombination.

Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates.

Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.

An optimized microRNA backbone for effective single-copy RNAi.

Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain.

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells.

Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD).

Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.

Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.

The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.

EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans.

CLP1 links tRNA metabolism to progressive motor-neuron loss.

Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.

Interlaboratory studies and initiatives developing standards for proteomics.

Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain.

Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.

Drosophila Embryo Stage Annotation using Label Propagation

Foamy virus for efficient gene transfer in regeneration studies.

Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program.

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.

Muscle and connective tissue progenitor populations show distinct Twist1 and Twist3 expression profiles during axolotl limb regeneration.

Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes.

An iron-rich organelle in the cuticular plate of avian hair cells.

A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain.

Parallel neural pathways mediate CO2 avoidance responses in Drosophila.

Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.

A directional tuning map of Drosophila elementary motion detectors.

A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors.

Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation.

CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis.

Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.

Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall.

Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics.

Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl.

Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.

GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.

Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics.

Transgenic mouse models enabling photolabeling of individual neurons in vivo.

Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment.

Progressive specification rather than intercalation of segments during limb regeneration.

Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho-site localization.

Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light.

The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.

Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.

Limb regeneration.

Protein-mediated transformation of lipid vesicles into tubular networks.

Life(span) in balance: oxygen fuels a sophisticated neural network for lifespan homeostasis in C. elegans.

Regulatory Genomics - Decoding Drosophila Regulatory Sequences.

Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.

Wapl is an essential regulator of chromatin structure and chromosome segregation.

High resolution anatomical mapping confirms the absence of a magnetic sense system in the rostral upper beak of pigeons.

Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.

Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans.

Deciphering the transcriptional cis-regulatory code.

Circadian and circalunar clock interactions in a marine annelid.

Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium.

Discrete neocortical dynamics predict behavioral categorization of sounds.

FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal.

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.

Centrosomes can initiate a polarity axis from any position within one-cell C. elegans embryos.

Methods in cell biology: analysis of cell polarity in C. elegans embryos.

Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities.

The Arabidopsis HEI10 is a new ZMM protein related to Zip3.

Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.

Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment.

Anatomy of the pectoral and forelimb muscles of wildtype and green fluorescent protein-transgenic axolotls and comparison with other tetrapods including humans: a basis for regenerative, evolutionary and developmental studies.

A pipeline for the generation of shRNA transgenic mice.

Neural crest does not contribute to the neck and shoulder in the axolotl (Ambystoma mexicanum).

Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3.

Induced heterodimerization and purification of two target proteins by a synthetic coiled-coil tag.

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.

Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.

A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis.

The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.

Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.

Dopamine neurons modulate pheromone responses in Drosophila courtship learning.

Regeneration and reprogramming.

Analysis of protein mixtures from whole-cell extracts by single-run nanoLC-MS/MS using ultralong gradients.

The blueprint of the type-3 injectisome.

Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain.

HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature.

Auditory circuit in the Drosophila brain.

Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing.

Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ.

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.

Reconstitution of the central and peripheral nervous system during salamander tail regeneration.

Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres.

Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.

Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison.

Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies.

A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss.

Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds.

The many functions of cohesin--different rings to rule them all?

Sister chromatid cohesion.

SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments.

Stem cells in the land of the rising sun: ISSCR 2012.

Diversity and roles of (t)RNA ligases.

A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells.

The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis.

CENP-T proteins are conserved centromere receptors of the Ndc80 complex.

Regenerative biology: Skin, heal thyself.

Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins.

Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.

The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior.

Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons.

APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.

Cancer stem cell definitions and terminology: the devil is in the details.

Seventy-five genetic loci influencing the human red blood cell.

Reshaping the optical dimension in optogenetics.

Essential role of EBF1 in the generation and function of distinct mature B cell types.

Actin branching in the initiation and maintenance of lamellipodia.

The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions.

Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin.

WNTing embryonic stem cells.

A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.

Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding.

Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation.

X Inactivation and Progenitor Cancer Cells

Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.

Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis.

A computational pipeline for comparative ChIP-seq analyses.

GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis.

General statistical modeling of data from protein relative expression isobaric tags.

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

Gene expression profile of the regeneration epithelium during axolotl limb regeneration.

HTRA proteases: regulated proteolysis in protein quality control.

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.

The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells.

Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse.

Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.

Using MATLAB to Achieve Nanoscale Optical Sectioning in the Vicinity of Metamaterial Substrates by Simulating Emitter-Substrate Interactions

Functional identification of optimized RNAi triggers using a massively parallel sensor assay.

Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails.

Vibrational excitons in ionophores: experimental probes for quantum coherence-assisted ion transport and selectivity in ion channels

Regulation of GATA-3 expression during CD4 lineage differentiation.

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome.

CTCF-binding elements mediate control of V(D)J recombination.

Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.

Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster.

A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.

Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir.

High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species.

Systematic phosphorylation analysis of human mitotic protein complexes.

Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins.

Neural-specific elongation of 3' UTRs during Drosophila development.

Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.

Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex.

An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs.

Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.

Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin.

Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.

Comment on 'Jobs for the boys'.

Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications.

Quality control in LC-MS/MS.

Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides.

Epigenetic regulation of learning and memory by Drosophila EHMT/G9a.

A blueprint for kinetochores - new insights into the molecular mechanics of cell division.

A high-resolution map of human evolutionary constraint using 29 mammals.

Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo.

Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation.

Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues.

The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells.

Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component.

Pax5: a master regulator of B cell development and leukemogenesis.

Protein quality control in the bacterial periplasm.

Limb regeneration: a new development?

Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.

A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells.

Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development.

Improved precision of iTRAQ and TMT quantification by an axial extraction field in