Publications | IMP Scientific Papers | Research Institute of Molecular Pathology (IMP)

The IMP publishes 60 to 90 scientific papers in international peer-review journals every year. This evidence for the productivity and high scientific standard of the IMP is listed here in full – a directory of all scientific publications by IMP scientists since the establishment of the institute, organised by years and research groups.

2017

Arnold, CD., Zabidi, MA., Pagani, M., Rath, M., Schernhuber, K., Kazmar, T., Stark, A. (2017) Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution. Nat Biotechnol. 35(2):136-144

Beckham, KS., Ciccarelli, L., Bunduc, CM., Mertens, HD., Ummels, R., Lugmayr, W., Mayr, J., Rettel, M., Savitski, MM., Svergun, DI., Bitter, W., Wilmanns, M., Marlovits, TC., Parret, AH., Houben, EN. (2017) Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis. Nat Microbiol. 2:17047

Breuss, MW., Hansen, AH., Landler, L., Keays, DA. (2017) Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. Behav Brain Res. 323:47-55

Breuss, MW., Leca, I., Gstrein, T., Hansen, AH., Keays, DA. (2017) Tubulins and brain development - The origins of functional specification. Mol Cell Neurosci.

Breuss, MW., Nguyen, T., Srivatsan, A., Leca, I., Tian, G., Fritz, T., Hansen, AH., Musaev, D., McEvoy-Venneri, J., James, KN., Rosti, RO., Scott, E., Tan, U., Kolodner, RD., Cowan, NJ., Keays, DA., Gleeson, JG. (2017) Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 26(2):258-269

Busslinger, GA., Stocsits, RR., van der Lelij, P., Axelsson, E., Tedeschi, A., Galjart, N., Peters, JM. (2017) Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl. Nature. 544(7651):503-507

Doblas, VG., Smakowska-Luzan, E., Fujita, S., Alassimone, J., Barberon, M., Madalinski, M., Belkhadir, Y., Geldner, N. (2017) Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor. Science. 355(6322):280-284

Franz, A., Shlyueva, D., Brunner, E., Stark, A., Basler, K. (2017) Probing the canonicity of the Wnt/Wingless signaling pathway. PLoS Genet. 13(4):e1006700

Greiner, G., Witzeneder, N., Berger, A., Schmetterer, K., Eisenwort, G., Schiefer, AI., Roos, S., Popow-Kraupp, T., Müllauer, L., Zuber, J., Sexl, V., Kenner, L., Sperr, WR., Valent, P., Mayerhofer, M., Hoermann, G. (2017) CCL2 is a KIT D816V-dependent modulator of the bone marrow microenvironment in systemic mastocytosis. Blood. 129(3):371-382

Hogg, SJ., Vervoort, SJ., Deswal, S., Ott, CJ., Li, J., Cluse, LA., Beavis, PA., Darcy, PK., Martin, BP., Spencer, A., Traunbauer, AK., Sadovnik, I., Bauer, K., Valent, P., Bradner, JE., Zuber, J., Shortt, J., Johnstone, RW. (2017) BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1. Cell Rep. 18(9):2162-2174

Housden, BE., Muhar, M., Gemberling, M., Gersbach, CA., Stainier, DY., Seydoux, G., Mohr, SE., Zuber, J., Perrimon, N. (2017) Loss-of-function genetic tools for animal models: cross-species and cross-platform differences. Nat Rev Genet. 18(1):24-40

Ishihara, K., Ranga, A., Lutolf, MP., Tanaka, EM., Meinhardt, A. (2017) Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells. Methods Mol Biol. 1597:43-55

Jang, H., Levy, S., Flavell, SW., Mende, F., Latham, R., Zimmer, M., Bargmann, CI. (2017) Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 114(7):E1263-E1272

Kreslavsky, T., Vilagos, B., Tagoh, H., Poliakova, DK., Schwickert, TA., Wöhner, M., Jaritz, M., Weiss, S., Taneja, R., Rossner, MJ., Busslinger, M. (2017) Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells. Nat Immunol. 18(4):442-455

Pajenda, S., Mechtler, K., Wagner, L. (2017) Urinary neprilysin in the critically ill patient. BMC Nephrol. 18(1):172

Pelossof, R., Fairchild, L., Huang, CH., Widmer, C., Sreedharan, VT., Sinha, N., Lai, DY., Guan, Y., Premsrirut, PK., Tschaharganeh, DF., Hoffmann, T., Thapar, V., Xiang, Q., Garippa, RJ., Rätsch, G., Zuber, J., Lowe, SW., Leslie, CS., Fellmann, C. (2017) Prediction of potent shRNAs with a sequential classification algorithm. Nat Biotechnol. 35(4):350-353

Reiter, F., Wienerroither, S., Stark, A. (2017) Combinatorial function of transcription factors and cofactors. Curr Opin Genet Dev. 43:73-81

Riley, NM., Hebert, AS., Dürnberger, G., Stanek, F., Mechtler, K., Westphall, MS., Coon, JJ. (2017) Phosphoproteomics with Activated Ion Electron Transfer Dissociation. Anal Chem.

Smeenk, L., Fischer, M., Jurado, S., Jaritz, M., Azaryan, A., Werner, B., Roth, M., Zuber, J., Stanulla, M., den Boer, ML., Mullighan, CG., Strehl, S., Busslinger, M. (2017) Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia. EMBO J. 36(6):718-735

Valerio, DG., Xu, H., Chen, CW., Hoshii, T., Eisold, ME., Delaney, C., Cusan, M., Deshpande, AJ., Huang, CH., Lujambio, A., Zheng, YG., Zuber, J., Pandita, TK., Lowe, SW., Armstrong, SA. (2017) Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis. Cancer Res. 77(7):1753-1762

Willems, S., Bouyssié, D., David, M., Locard-Paulet, M., Mechtler, K., Schwämmle, V., Uszkoreit, J., Vaudel, M., Dorfer, V. (2017) Proceedings of the EuBIC Winter School 2017. J Proteomics.

2016

Adams, WC., Chen, YH., Kratchmarov, R., Yen, B., Nish, SA., Lin, WW., Rothman, NJ., Luchsinger, LL., Klein, U., Busslinger, M., Rathmell, JC., Snoeck, HW., Reiner, SL. (2016) Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal. Cell Rep. 17(12):3142-3152

Ali, AK., Oh, JS., Vivier, E., Busslinger, M., Lee, SH. (2016) NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation. J Immunol. 196(4):1753-67

Asaoka, T., Almagro, J., Ehrhardt, C., Tsai, I., Schleiffer, A., Deszcz, L., Junttila, S., Ringrose, L., Mechtler, K., Kavirayani, A., Gyenesei, A., Hofmann, K., Duchek, P., Rittinger, K., Ikeda, F. (2016) Linear ubiquitination by LUBEL has a role in Drosophila heat stress response. EMBO Rep. 17(11):1624-1640

Baker, A., Gregory, GP., Verbrugge, I., Kats, L., Hilton, JJ., Vidacs, E., Lee, EM., Lock, RB., Zuber, J., Shortt, J., Johnstone, RW. (2016) The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia. Cancer Res. 76(5):1158-69

Bigenzahn, JW., Fauster, A., Rebsamen, M., Kandasamy, RK., Scorzoni, S., Vladimer, GI., Müller, AC., Gstaiger, M., Zuber, J., Bennett, KL., Superti-Furga, G. (2016) An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client. Mol Cell Proteomics. 15(3):1139-50

Breuss, M., Fritz, T., Gstrein, T., Chan, K., Ushakova, L., Yu, N., Vonberg, FW., Werner, B., Elling, U., Keays, DA. (2016) Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis. Development. 143(7):1126-33

Broix, L., Jagline, H., L Ivanova, E., Schmucker, S., Drouot, N., Clayton-Smith, J., Pagnamenta, AT., Metcalfe, KA., Isidor, B., Louvier, UW., Poduri, A., Taylor, JC., Tilly, P., Poirier, K., Saillour, Y., Lebrun, N., Stemmelen, T., Rudolf, G., Muraca, G., Saintpierre, B., Elmorjani, A., Moïse, M., Weirauch, NB., Guerrini, R., Boland, A., Olaso, R., Masson, C., Tripathy, R., Keays, D., Beldjord, C., Nguyen, L., Godin, J., Kini, U., Nischké, P., Deleuze, JF., Bahi-Buisson, N., Sumara, I., Hinckelmann, MV., Chelly, J. (2016) Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 48(11):1349-1358

Brown, NG., VanderLinden, R., Watson, ER., Weissmann, F., Ordureau, A., Wu, KP., Zhang, W., Yu, S., Mercredi, PY., Harrison, JS., Davidson, IF., Qiao, R., Lu, Y., Dube, P., Brunner, MR., Grace, CR., Miller, DJ., Haselbach, D., Jarvis, MA., Yamaguchi, M., Yanishevski, D., Petzold, G., Sidhu, SS., Kuhlman, B., Kirschner, MW., Harper, JW., Peters, JM., Stark, H., Schulman, BA. (2016) Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell. 165(6):1440-53

Cabrera-Quio, LE., Herberg, S., Pauli, A. (2016) Decoding sORF translation - from small proteins to gene regulation. RNA Biol. 13(11):1051-1059

Camurdanoglu, BZ., Hrovat, C., Dürnberger, G., Madalinski, M., Mechtler, K., Herbst, R. (2016) Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop. Sci Rep. 6:33583

Davidson, IF., Goetz, D., Zaczek, MP., Molodtsov, MI., Huis In 't Veld, PJ., Weissmann, F., Litos, G., Cisneros, DA., Ocampo-Hafalla, M., Ladurner, R., Uhlmann, F., Vaziri, A., Peters, JM. (2016) Rapid movement and transcriptional re-localization of human cohesin on DNA. EMBO J. 35(24):2671-2685

Delconte, RB., Shi, W., Sathe, P., Ushiki, T., Seillet, C., Minnich, M., Kolesnik, TB., Rankin, LC., Mielke, LA., Zhang, JG., Busslinger, M., Smyth, MJ., Hutchinson, DS., Nutt, SL., Nicholson, SE., Alexander, WS., Corcoran, LM., Vivier, E., Belz, GT., Carotta, S., Huntington, ND. (2016) The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15. Immunity. 44(1):103-15

Dietsche, T., Tesfazgi Mebrhatu, M., Brunner, MJ., Abrusci, P., Yan, J., Franz-Wachtel, M., Schärfe, C., Zilkenat, S., Grin, I., Galán, JE., Kohlbacher, O., Lea, S., Macek, B., Marlovits, TC., Robinson, CV., Wagner, S. (2016) Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus. PLoS Pathog. 12(12):e1006071

Drexel, T., Mahofsky, K., Latham, R., Zimmer, M., Cochella, L. (2016) Neuron type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans. Genes Dev. 30(18):2042-2047

Gallego, LD., Ghodgaonkar Steger, M., Polyansky, AA., Schubert, T., Zagrovic, B., Zheng, N., Clausen, T., Herzog, F., Köhler, A. (2016) Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1. Proc Natl Acad Sci U S A. 113(38):10553-8

Ghisi, M., Kats, L., Masson, F., Li, J., Kratina, T., Vidacs, E., Gilan, O., Doyle, MA., Newbold, A., Bolden, JE., Fairfax, KA., de Graaf, CA., Firth, M., Zuber, J., Dickins, RA., Corcoran, LM., Dawson, MA., Belz, GT., Johnstone, RW. (2016) Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia. Cancer Cell. 30(1):59-74

Haas, MA., Ngo, L., Li, SS., Schleich, S., Qu, Z., Vanyai, HK., Cullen, HD., Cardona-Alberich, A., Gladwyn-Ng, IE., Pagnamenta, AT., Taylor, JC., Stewart, H., Kini, U., Duncan, KE., Teleman, AA., Keays, DA., Heng, JI. (2016) De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation. Cell Rep. 15(10):2251-65

Hempel, A., Pagnamenta, AT., Blyth, M., Mansour, S., McConnell, V., Kou, I., Ikegawa, S., Tsurusaki, Y., Matsumoto, N., Lo-Castro, A., Plessis, G., Albrecht, B., Battaglia, A., Taylor, JC., Howard, MF., Keays, D., Sohal, AS., Kühl, SJ., Kini, U., McNeill, A. (2016) Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome. J Med Genet. 53(3):152-62

Heuck, A., Schitter-Sollner, S., Suskiewicz, MJ., Kurzbauer, R., Kley, J., Schleiffer, A., Rombaut, P., Herzog, F., Clausen, T. (2016) Structural basis for the disaggregase activity and regulation of Hsp104. Elife. 5

Hons, MT., Huis In 't Veld, PJ., Kaesler, J., Rombaut, P., Schleiffer, A., Herzog, F., Stark, H., Peters, JM. (2016) Topology and structure of an engineered human cohesin complex bound to Pds5B. Nat Commun. 7:12523

Houben, A., Kostanova-Poliakova, D., Weissenböck, M., Graf, J., Teufel, S., von der Mark, K., Hartmann, C. (2016) β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 143(20):3826-3838

Huis In 't Veld, PJ., Jeganathan, S., Petrovic, A., Singh, P., John, J., Krenn, V., Weissmann, F., Bange, T., Musacchio, A. (2016) Molecular basis of outer kinetochore assembly on CENP-T. Elife. 5

Hums, I., Riedl, J., Mende, F., Kato, S., Kaplan, HS., Latham, R., Sonntag, M., Traunmüller, L., Zimmer, M. (2016) Regulation of two motor patterns enables the gradual adjustment of locomotion strategy in Caenorhabditis elegans. Elife. 5

Isokane, M., Walter, T., Mahen, R., Nijmeijer, B., Hériché, JK., Miura, K., Maffini, S., Ivanov, MP., Kitajima, TS., Peters, JM., Ellenberg, J. (2016) ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores. J Cell Biol. 212(6):647-59

Jarvis, MA., Brown, NG., Watson, ER., VanderLinden, R., Schulman, BA., Peters, JM. (2016) Measuring APC/C-Dependent Ubiquitylation In Vitro. Methods Mol Biol. 1342:287-303

Kaufmann, T., Kukolj, E., Brachner, A., Beltzung, E., Bruno, M., Kostrhon, S., Opravil, S., Hudecz, O., Mechtler, K., Warren, G., Slade, D. (2016) SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 129(24):4607-4621

Kiermaier, E., Moussion, C., Veldkamp, CT., Gerardy-Schahn, R., de Vries, I., Williams, LG., Chaffee, GR., Phillips, AJ., Freiberger, F., Imre, R., Taleski, D., Payne, RJ., Braun, A., Förster, R., Mechtler, K., Mühlenhoff, M., Volkman, BF., Sixt, M. (2016) Polysialylation controls dendritic cell trafficking by regulating chemokine recognition. Science. 351(6269):186-90

Kim, JS., He, X., Orr, B., Wutz, G., Hill, V., Peters, JM., Compton, DA., Waldman, T. (2016) Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2. PLoS Genet. 12(2):e1005865

Kollmann, K., Heller, G., Schneckenleithner, C., Warsch, W., Scheicher, R., Ott, RG., Schäfer, M., Fajmann, S., Schlederer, M., Schiefer, AI., Reichart, U., Mayerhofer, M., Hoeller, C., Zöchbauer-Müller, S., Kerjaschki, D., Bock, C., Kenner, L., Hoefler, G., Freissmuth, M., Green, AR., Moriggl, R., Busslinger, M., Malumbres, M., Sexl, V. (2016) A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis. Cancer Cell. 30(2):359-360

Ladurner, R., Kreidl, E., Ivanov, MP., Ekker, H., Idarraga-Amado, MH., Busslinger, GA., Wutz, G., Cisneros, DA., Peters, JM. (2016) Sororin actively maintains sister chromatid cohesion. EMBO J. 35(6):635-53

Lange, L., Pagnamenta, AT., Lise, S., Clasper, S., Stewart, H., Akha, ES., Quaghebeur, G., Knight, SJ., Keays, DA., Taylor, JC., Kini, U. (2016) A de novo frameshift in HNRNPK causing a Kabuki-like syndrome with nodular heterotopia. Clin Genet. 90(3):258-62

Leong, YA., Chen, Y., Ong, HS., Wu, D., Man, K., Deleage, C., Minnich, M., Meckiff, BJ., Wei, Y., Hou, Z., Zotos, D., Fenix, KA., Atnerkar, A., Preston, S., Chipman, JG., Beilman, GJ., Allison, CC., Sun, L., Wang, P., Xu, J., Toe, JG., Lu, HK., Tao, Y., Palendira, U., Dent, AL., Landay, AL., Pellegrini, M., Comerford, I., McColl, SR., Schacker, TW., Long, HM., Estes, JD., Busslinger, M., Belz, GT., Lewin, SR., Kallies, A., Yu, D. (2016) CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles. Nat Immunol. 17(10):1187-96

Mackay, LK., Minnich, M., Kragten, NA., Liao, Y., Nota, B., Seillet, C., Zaid, A., Man, K., Preston, S., Freestone, D., Braun, A., Wynne-Jones, E., Behr, FM., Stark, R., Pellicci, DG., Godfrey, DI., Belz, GT., Pellegrini, M., Gebhardt, T., Busslinger, M., Shi, W., Carbone, FR., van Lier, RA., Kallies, A., van Gisbergen, KP. (2016) Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes. Science. 352(6284):459-63

Meshcheryakova, A., Svoboda, M., Tahir, A., Köfeler, HC., Triebl, A., Mungenast, F., Heinze, G., Gerner, C., Zimmermann, P., Jaritz, M., Mechtcheriakova, D. (2016) Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach. Oncotarget. 7(16):22295-323

Minnich, M., Tagoh, H., Bönelt, P., Axelsson, E., Fischer, M., Cebolla, B., Tarakhovsky, A., Nutt, SL., Jaritz, M., Busslinger, M. (2016) Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation. Nat Immunol. 17(3):331-43

Mlecnik, B., Bindea, G., Kirilovsky, A., Angell, HK., Obenauf, AC., Tosolini, M., Church, SE., Maby, P., Vasaturo, A., Angelova, M., Fredriksen, T., Mauger, S., Waldner, M., Berger, A., Speicher, MR., Pagès, F., Valge-Archer, V., Galon, J. (2016) The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis. Sci Transl Med. 8(327):327ra26

Molodtsov, MI., Mieck, C., Dobbelaere, J., Dammermann, A., Westermann, S., Vaziri, A. (2016) A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation. Cell. 167(2):539-552.e14

Moreno, E., McGaughran, A., Rödelsperger, C., Zimmer, M., Sommer, RJ. (2016) Oxygen-induced social behaviours in Pristionchus pacificus have a distinct evolutionary history and genetic regulation from Caenorhabditis elegans. Proc Biol Sci. 283(1825):20152263

Muerdter, F., Stark, A. (2016) Gene Regulation: Activation through Space. Curr Biol. 26(19):R895-R898

Nowacka, JD., Baumgartner, C., Pelorosso, C., Roth, M., Zuber, J., Baccarini, M. (2016) MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 7(49):80113-80130

Pagnamenta, AT., Howard, MF., Knight, SJ., Keays, DA., Quaghebeur, G., Taylor, JC., Kini, U. (2016) Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities. Clin Case Rep. 4(10):952-956

Pang, SH., Minnich, M., Gangatirkar, P., Zheng, Z., Ebert, A., Song, G., Dickins, RA., Corcoran, LM., Mullighan, CG., Busslinger, M., Huntington, ND., Nutt, SL., Carotta, S. (2016) PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia. Leukemia. 30(6):1375-87

Panser, K., Tirian, L., Schulze, F., Villalba, S., Jefferis, GS., Bühler, K., Straw, AD. (2016) Automatic Segmentation of Drosophila Neural Compartments Using GAL4 Expression Data Reveals Novel Visual Pathways. Curr Biol. 26(15):1943-54

Pasquarella, A., Ebert, A., Pereira de Almeida, G., Hinterberger, M., Kazerani, M., Nuber, A., Ellwart, J., Klein, L., Busslinger, M., Schotta, G. (2016) Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells. Development. 143(10):1788-99

Pekgöz Altunkaya, G., Malvezzi, F., Demianova, Z., Zimniak, T., Litos, G., Weissmann, F., Mechtler, K., Herzog, F., Westermann, S. (2016) CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore. Curr Biol. 26(17):2370-8

Polakova, S., Molnarova, L., Hyppa, RW., Benko, Z., Misova, I., Schleiffer, A., Smith, GR., Gregan, J. (2016) Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation. PLoS Genet. 12(6):e1006102

Prevedel, R., Verhoef, AJ., Pernía-Andrade, AJ., Weisenburger, S., Huang, BS., Nöbauer, T., Fernández, A., Delcour, JE., Golshani, P., Baltuska, A., Vaziri, A. (2016) Fast volumetric calcium imaging across multiple cortical layers using sculpted light. Nat Methods. 13(12):1021-1028

Qiao, R., Weissmann, F., Yamaguchi, M., Brown, NG., VanderLinden, R., Imre, R., Jarvis, MA., Brunner, MR., Davidson, IF., Litos, G., Haselbach, D., Mechtler, K., Stark, H., Schulman, BA., Peters, JM. (2016) Mechanism of APC/CCDC20 activation by mitotic phosphorylation. Proc Natl Acad Sci U S A. 113(19):E2570-8

Rampler, E., Stranzl, T., Orban-Nemeth, Z., Hollenstein, DM., Hudecz, O., Schlögelhofer, P., Mechtler, K. (2016) Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1". J Proteome Res. 15(5):1732

Reddien, PW., Tanaka, EM. (2016) Editorial overview: Cell reprogramming, regeneration and repair. Curr Opin Genet Dev. 40:iv-vi

Reimão-Pinto, MM., Manzenreither, RA., Burkard, TR., Sledz, P., Jinek, M., Mechtler, K., Ameres, SL. (2016) Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila. EMBO J. 35(22):2417-2434

Rickels, R., Hu, D., Collings, CK., Woodfin, AR., Piunti, A., Mohan, M., Herz, HM., Kvon, E., Shilatifard, A. (2016) An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS. Mol Cell. 63(2):318-28

Sdelci, S., Lardeau, CH., Tallant, C., Klepsch, F., Klaiber, B., Bennett, J., Rathert, P., Schuster, M., Penz, T., Fedorov, O., Superti-Furga, G., Bock, C., Zuber, J., Huber, KV., Knapp, S., Müller, S., Kubicek, S. (2016) Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. Nat Chem Biol. 12(7):504-10

Shlyueva, D., Meireles-Filho, AC., Pagani, M., Stark, A. (2016) Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation. PLoS One. 11(8):e0161997

Sigl, V., Owusu-Boaitey, K., Joshi, PA., Kavirayani, A., Wirnsberger, G., Novatchkova, M., Kozieradzki, I., Schramek, D., Edokobi, N., Hersl, J., Sampson, A., Odai-Afotey, A., Lazaro, C., Gonzalez-Suarez, E., Pujana, MA., Cimba, F., Heyn, H., Vidal, E., Cruickshank, J., Berman, H., Sarao, R., Ticevic, M., Uribesalgo, I., Tortola, L., Rao, S., Tan, Y., Pfeiler, G., Lee, EY., Bago-Horvath, Z., Kenner, L., Popper, H., Singer, C., Khokha, R., Jones, LP., Penninger, JM. (2016) RANKL/RANK control Brca1 mutation-driven mammary tumors. Cell Res. 26(7):761-74

Smaldone, G., Pirone, L., Pedone, E., Marlovits, T., Vitagliano, L., Ciccarelli, L. (2016) The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states. FEBS Lett. 590(11):1663-71

Stepien, BK., Oppitz, C., Gerlach, D., Dag, U., Novatchkova, M., Krüttner, S., Stark, A., Keleman, K. (2016) RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2. Proc Natl Acad Sci U S A.

Suskiewicz, MJ., Clausen, T. (2016) Chemical Biology Interrogates Protein Arginine Phosphorylation. Cell Chem Biol. 23(8):888-90

Tellier, J., Shi, W., Minnich, M., Liao, Y., Crawford, S., Smyth, GK., Kallies, A., Busslinger, M., Nutt, SL. (2016) Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response. Nat Immunol. 17(3):323-30

Tinsley, JN., Molodtsov, MI., Prevedel, R., Wartmann, D., Espigulé-Pons, J., Lauwers, M., Vaziri, A. (2016) Direct detection of a single photon by humans. Nat Commun. 7:12172

Tordella, L., Khan, S., Hohmeyer, A., Banito, A., Klotz, S., Raguz, S., Martin, N., Dhamarlingam, G., Carroll, T., González Meljem, JM., Deswal, S., Martínez-Barbera, JP., García-Escudero, R., Zuber, J., Zender, L., Gil, J. (2016) SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer. Genes Dev. 30(19):2187-2198

Trapp, M., Schulze, F., Novikov, AA., Tirian, L., J Dickson, B., Bühler, K. (2016) Adaptive and Background-Aware GAL4 Expression Enhancement of Co-registered Confocal Microscopy Images. Neuroinformatics. 14(2):221-33

Trentini, DB., Suskiewicz, MJ., Heuck, A., Kurzbauer, R., Deszcz, L., Mechtler, K., Clausen, T. (2016) Arginine phosphorylation marks proteins for degradation by a Clp protease. Nature. 539(7627):48-53

Valent, P., Groner, B., Schumacher, U., Superti-Furga, G., Busslinger, M., Kralovics, R., Zielinski, C., Penninger, JM., Kerjaschki, D., Stingl, G., Smolen, JS., Valenta, R., Lassmann, H., Kovar, H., Jäger, U., Kornek, G., Müller, M., Sörgel, F. (2016) Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine. J Innate Immun. 8(2):111-20

Weissmann, F., Petzold, G., VanderLinden, R., Huis In 't Veld, PJ., Brown, NG., Lampert, F., Westermann, S., Stark, H., Schulman, BA., Peters, JM. (2016) biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes. Proc Natl Acad Sci U S A. 113(19):E2564-9

Wiedemann, EM., Peycheva, M., Pavri, R. (2016) DNA Replication Origins in Immunoglobulin Switch Regions Regulate Class Switch Recombination in an R-Loop-Dependent Manner. Cell Rep. 17(11):2927-2942

Wissel, S., Kieser, A., Yasugi, T., Duchek, P., Roitinger, E., Gokcezade, J., Steinmann, V., Gaul, U., Mechtler, K., Förstemann, K., Knoblich, JA., Neumüller, RA. (2016) A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function. G3 (Bethesda). 6(8):2467-78

Witham, E., Comunian, C., Ratanpal, H., Skora, S., Zimmer, M., Srinivasan, S. (2016) C. elegans Body Cavity Neurons Are Homeostatic Sensors that Integrate Fluctuations in Oxygen Availability and Internal Nutrient Reserves. Cell Rep. 14(7):1641-54

Wöhner, M., Tagoh, H., Bilic, I., Jaritz, M., Poliakova, DK., Fischer, M., Busslinger, M. (2016) Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development. J Exp Med. 213(7):1201-21

Yamaguchi, M., VanderLinden, R., Weissmann, F., Qiao, R., Dube, P., Brown, NG., Haselbach, D., Zhang, W., Sidhu, SS., Peters, JM., Stark, H., Schulman, BA. (2016) Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation. Mol Cell. 63(4):593-607

Zabidi, MA., Stark, A. (2016) Regulatory Enhancer-Core-Promoter Communication via Transcription Factors and Cofactors. Trends Genet. 32(12):801-814

2015

Alpert, AJ., Hudecz, O., Mechtler, K. (2015) Anion-exchange chromatography of phosphopeptides: weak anion exchange versus strong anion exchange and anion-exchange chromatography versus electrostatic repulsion-hydrophilic interaction chromatography. Anal Chem. 87(9):4704-11

Bigenzahn, JW., Fauster, A., Rebsamen, M., Kandasamy, RK., Scorzoni, S., Vladimer, GI., Mueller, AC., Gstaiger, M., Zuber, J., Bennett, KL., Superti-Furga, G. (2015) An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies MLKL as an HSP90 client. Mol Cell Proteomics.

Breuss, M., Morandell, J., Nimpf, S., Gstrein, T., Lauwers, M., Hochstoeger, T., Braun, A., Chan, K., Sánchez Guajardo, ER., Zhang, L., Suplata, M., Heinze, KG., Elsayad, K., Keays, DA. (2015) The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons. J Comp Neurol. 523(15):2161-86

Brondfield, S., Umesh, S., Corella, A., Zuber, J., Rappaport, AR., Gaillard, C., Lowe, SW., Goga, A., Kogan, SC. (2015) Direct and indirect targeting of MYC to treat acute myeloid leukemia. Cancer Chemother Pharmacol. 76(1):35-46

Brown, NG., VanderLinden, R., Watson, ER., Qiao, R., Grace, CR., Yamaguchi, M., Weissmann, F., Frye, JJ., Dube, P., Ei Cho, S., Actis, ML., Rodrigues, P., Fujii, N., Peters, JM., Stark, H., Schulman, BA. (2015) RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex. Proc Natl Acad Sci U S A. 112(17):5272-9

Chari, A., Haselbach, D., Kirves, JM., Ohmer, J., Paknia, E., Fischer, N., Ganichkin, O., Möller, V., Frye, JJ., Petzold, G., Jarvis, M., Tietzel, M., Grimm, C., Peters, JM., Schulman, BA., Tittmann, K., Markl, J., Fischer, U., Stark, H. (2015) ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space. Nat Methods. 12(9):859-65

Cheloufi, S., Elling, U., Hopfgartner, B., Jung, YL., Murn, J., Ninova, M., Hubmann, M., Badeaux, AI., Euong Ang, C., Tenen, D., Wesche, DJ., Abazova, N., Hogue, M., Tasdemir, N., Brumbaugh, J., Rathert, P., Jude, J., Ferrari, F., Blanco, A., Fellner, M., Wenzel, D., Zinner, M., Vidal, SE., Bell, O., Stadtfeld, M., Chang, HY., Almouzni, G., Lowe, SW., Rinn, J., Wernig, M., Aravin, A., Shi, Y., Park, PJ., Penninger, JM., Zuber, J., Hochedlinger, K. (2015) The histone chaperone CAF-1 safeguards somatic cell identity. Nature. 528(7581):218-24

Chirn, GW., Rahman, R., Sytnikova, YA., Matts, JA., Zeng, M., Gerlach, D., Yu, M., Berger, B., Naramura, M., Kile, BT., Lau, NC. (2015) Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals. PLoS Genet. 11(11):e1005652

DiMaio, F., Song, Y., Li, X., Brunner, MJ., Xu, C., Conticello, V., Egelman, E., Marlovits, TC., Cheng, Y., Baker, D. (2015) Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement. Nat Methods. 12(4):361-5

Ebert, A., Hill, L., Busslinger, M. (2015) Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci. Adv Immunol. 128:93-121

Edelman, NB., Fritz, T., Nimpf, S., Pichler, P., Lauwers, M., Hickman, RW., Papadaki-Anastasopoulou, A., Ushakova, L., Heuser, T., Resch, GP., Saunders, M., Shaw, JA., Keays, DA. (2015) No evidence for intracellular magnetite in putative vertebrate magnetoreceptors identified by magnetic screening. Proc Natl Acad Sci U S A. 112(1):262-7

Fenton, RA., Poulsen, SB., de la Mora Chavez, S., Soleimani, M., Busslinger, M., Dominguez Rieg, JA., Rieg, T. (2015) Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3. Am J Physiol Renal Physiol. 308(12):F1409-20

Grabner, B., Schramek, D., Mueller, KM., Moll, HP., Svinka, J., Hoffmann, T., Bauer, E., Blaas, L., Hruschka, N., Zboray, K., Stiedl, P., Nivarthi, H., Bogner, E., Gruber, W., Mohr, T., Zwick, RH., Kenner, L., Poli, V., Aberger, F., Stoiber, D., Egger, G., Esterbauer, H., Zuber, J., Moriggl, R., Eferl, R., Győrffy, B., Penninger, JM., Popper, H., Casanova, E. (2015) Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 6:6285

Grebien, F., Vedadi, M., Getlik, M., Giambruno, R., Grover, A., Avellino, R., Skucha, A., Vittori, S., Kuznetsova, E., Smil, D., Barsyte-Lovejoy, D., Li, F., Poda, G., Schapira, M., Wu, H., Dong, A., Senisterra, G., Stukalov, A., Huber, KV., Schönegger, A., Marcellus, R., Bilban, M., Bock, C., Brown, PJ., Zuber, J., Bennett, KL., Al-Awar, R., Delwel, R., Nerlov, C., Arrowsmith, CH., Superti-Furga, G. (2015) Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. Nat Chem Biol. 11(10):815

Haberle, V., Stark, A. (2015) Coordinating the human looks. Cell. 163(1):24-6

Heier, C., Radner, FP., Moustafa, T., Schreiber, R., Grond, S., Eichmann, TO., Schweiger, M., Schmidt, A., Cerk, IK., Oberer, M., Theussl, HC., Wojciechowski, J., Penninger, JM., Zimmermann, R., Zechner, R. (2015) G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis. J Biol Chem. 290(43):26141-50

Iacovella, MG., Golfieri, C., Massari, LF., Busnelli, S., Pagliuca, C., Dal Maschio, M., Infantino, V., Visintin, R., Mechtler, K., Ferreira-Cerca, S., De Wulf, P. (2015) Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation. Nat Commun. 6:6643

Ilkovski, B., Pagnamenta, AT., O'Grady, GL., Kinoshita, T., Howard, MF., Lek, M., Thomas, B., Turner, A., Christodoulou, J., Sillence, D., Knight, SJ., Popitsch, N., Keays, DA., Anzilotti, C., Goriely, A., Waddell, LB., Brilot, F., North, KN., Kanzawa, N., Macarthur, DG., Taylor, JC., Kini, U., Murakami, Y., Clarke, NF. (2015) Mutations in PIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies. Hum Mol Genet. 24(21):6146-59

Isrie, M., Breuss, M., Tian, G., Hansen, AH., Cristofoli, F., Morandell, J., Kupchinsky, ZA., Sifrim, A., Rodriguez-Rodriguez, CM., Dapena, EP., Doonanco, K., Leonard, N., Tinsa, F., Moortgat, S., Ulucan, H., Koparir, E., Karaca, E., Katsanis, N., Marton, V., Vermeesch, JR., Davis, EE., Cowan, NJ., Keays, DA., Van Esch, H. (2015) Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type. Am J Hum Genet. 97(6):790-800

Kato, S., Kaplan, HS., Schrödel, T., Skora, S., Lindsay, TH., Yemini, E., Lockery, S., Zimmer, M. (2015) Global brain dynamics embed the motor command sequence of Caenorhabditis elegans. Cell. 163(3):656-69

Khattak, S., Tanaka, EM. (2015) Transgenesis in axolotl (Ambystoma mexicanum). Methods Mol Biol. 1290:269-77

Krüttner, S., Traunmüller, L., Dag, U., Jandrasits, K., Stepien, B., Iyer, N., Fradkin, LG., Noordermeer, JN., Mensh, BD., Keleman, K. (2015) Synaptic Orb2A Bridges Memory Acquisition and Late Memory Consolidation in Drosophila. Cell Rep. 11(12):1953-65

Kulinski, TM., Casari, MR., Guenzl, PM., Wenzel, D., Andergassen, D., Hladik, A., Datlinger, P., Farlik, M., Theussl, HC., Penninger, JM., Knapp, S., Bock, C., Barlow, DP., Hudson, QJ. (2015) Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol. 402(2):291-305

Lambing, C., Osman, K., Nuntasoontorn, K., West, A., Higgins, JD., Copenhaver, GP., Yang, J., Armstrong, SJ., Mechtler, K., Roitinger, E., Franklin, FC. (2015) Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers. PLoS Genet. 11(7):e1005372

Loewenstein, Y., Yanover, U., Rumpel, S. (2015) Predicting the Dynamics of Network Connectivity in the Neocortex. J Neurosci. 35(36):12535-44

Matthews, GM., Mehdipour, P., Cluse, LA., Falkenberg, KJ., Wang, E., Roth, M., Santoro, F., Vidacs, E., Stanley, K., House, CM., Rusche, JR., Vakoc, CR., Zuber, J., Minucci, S., Johnstone, RW. (2015) Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies. Blood. 126(21):2392-403

Mieck, C., Molodtsov, MI., Drzewicka, K., van der Vaart, B., Litos, G., Schmauss, G., Vaziri, A., Westermann, S. (2015) Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3. Elife. 4

Muerdter, F., Boryń, ŁM., Arnold, CD. (2015) STARR-seq - principles and applications. Genomics. 106(3):145-50

Murn, J., Zarnack, K., Yang, YJ., Durak, O., Murphy, EA., Cheloufi, S., Gonzalez, DM., Teplova, M., Curk, T., Zuber, J., Patel, DJ., Ule, J., Luscombe, NM., Tsai, LH., Walsh, CA., Shi, Y. (2015) Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes Dev. 29(5):501-12

Nagy, V., Cole, T., Van Campenhout, C., Khoung, TM., Leung, C., Vermeiren, S., Novatchkova, M., Wenzel, D., Cikes, D., Polyansky, AA., Kozieradzki, I., Meixner, A., Bellefroid, EJ., Neely, GG., Penninger, JM. (2015) The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception. Cell Cycle. 14(12):1799-808

Nasso, S., Hartler, J., Trajanoski, Z., Di Camillo, B., Mechtler, K., Toffolo, GM. (2015) 3DSpectra: A 3-dimensional quantification algorithm for LC-MS labeled profile data. J Proteomics. 112:156-65

Nutt, SL., Heavey, B., Rolink, AG., Busslinger, M. (2015) Pillars Article: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999. 401: 556-562. J Immunol. 195(3):766-72

Ohnmacht, C., Park, JH., Cording, S., Wing, JB., Atarashi, K., Obata, Y., Gaboriau-Routhiau, V., Marques, R., Dulauroy, S., Fedoseeva, M., Busslinger, M., Cerf-Bensussan, N., Boneca, IG., Voehringer, D., Hase, K., Honda, K., Sakaguchi, S., Eberl, G. (2015) MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells. Science. 349(6251):989-93

Pagnamenta, AT., Howard, MF., Wisniewski, E., Popitsch, N., Knight, SJ., Keays, DA., Quaghebeur, G., Cox, H., Cox, P., Balla, T., Taylor, JC., Kini, U. (2015) Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis. Hum Mol Genet. 24(13):3732-41

Pauli, A., Montague, TG., Lennox, KA., Behlke, MA., Schier, AF. (2015) Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish. PLoS One. 10(10):e0139504

Phadnis, N., Cipak, L., Polakova, S., Hyppa, RW., Cipakova, I., Anrather, D., Karvaiova, L., Mechtler, K., Smith, GR., Gregan, J. (2015) Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation. PLoS Genet. 11(5):e1005225

Poepsel, S., Sprengel, A., Sacca, B., Kaschani, F., Kaiser, M., Gatsogiannis, C., Raunser, S., Clausen, T., Ehrmann, M. (2015) Determinants of amyloid fibril degradation by the PDZ protease HTRA1. Nat Chem Biol. 11(11):862-9

Rampler, E., Stranzl, T., Orban-Nemeth, Z., Hollenstein, DM., Hudecz, O., Schloegelhofer, P., Mechtler, K. (2015) Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1. J Proteome Res. 14(12):5048-62

Rathert, P., Roth, M., Neumann, T., Muerdter, F., Roe, JS., Muhar, M., Deswal, S., Cerny-Reiterer, S., Peter, B., Jude, J., Hoffmann, T., Boryń, ŁM., Axelsson, E., Schweifer, N., Tontsch-Grunt, U., Dow, LE., Gianni, D., Pearson, M., Valent, P., Stark, A., Kraut, N., Vakoc, CR., Zuber, J. (2015) Transcriptional plasticity promotes primary and acquired resistance to BET inhibition. Nature. 525(7570):543-7

Rodrigo Albors, A., Tanaka, EM. (2015) High-efficiency electroporation of the spinal cord in larval axolotl. Methods Mol Biol. 1290:115-25

Rodrigo Albors, A., Tazaki, A., Rost, F., Nowoshilow, S., Chara, O., Tanaka, EM. (2015) Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration. Elife. 4:e10230

Roitinger, E., Hofer, M., Köcher, T., Pichler, P., Novatchkova, M., Yang, J., Schlögelhofer, P., Mechtler, K. (2015) Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana. Mol Cell Proteomics. 14(3):556-71

Rudolph, D., Impagnatiello, MA., Blaukopf, C., Sommer, C., Gerlich, DW., Roth, M., Tontsch-Grunt, U., Wernitznig, A., Savarese, F., Hofmann, MH., Albrecht, C., Geiselmann, L., Reschke, M., Garin-Chesa, P., Zuber, J., Moll, J., Adolf, GR., Kraut, N. (2015) Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia. J Pharmacol Exp Ther. 352(3):579-89

Rupprecht, P., Prevedel, R., Groessl, F., Haubensak, WE., Vaziri, A. (2015) Optimizing and extending light-sculpting microscopy for fast functional imaging in neuroscience. Biomed Opt Express. 6(2):353-68

Salmon, JM., Bots, M., Vidacs, E., Stanley, KL., Atadja, P., Zuber, J., Johnstone, RW. (2015) Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia. Clin Epigenetics. 7:2

Scheicher, R., Hoelbl-Kovacic, A., Bellutti, F., Tigan, AS., Prchal-Murphy, M., Heller, G., Schneckenleithner, C., Salazar-Roa, M., Zöchbauer-Müller, S., Zuber, J., Malumbres, M., Kollmann, K., Sexl, V. (2015) CDK6 as a key regulator of hematopoietic and leukemic stem cell activation. Blood. 125(1):90-101

Schneider, M., Hellerschmied, D., Schubert, T., Amlacher, S., Vinayachandran, V., Reja, R., Pugh, BF., Clausen, T., Köhler, A. (2015) The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression. Cell. 162(5):1016-28

Schwarzer, A., Holtmann, H., Brugman, M., Meyer, J., Schauerte, C., Zuber, J., Steinemann, D., Schlegelberger, B., Li, Z., Baum, C. (2015) Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia. Oncogene. 34(27):3593-604

Segre, PS., Dakin, R., Zordan, VB., Dickinson, MH., Straw, AD., Altshuler, DL. (2015) Burst muscle performance predicts the speed, acceleration, and turning performance of Anna's hummingbirds. Elife. 4:e11159

Sezer, U., Wörner, L., Horak, J., Felix, L., Tüxen, J., Götz, C., Vaziri, A., Mayor, M., Arndt, M. (2015) Laser-induced acoustic desorption of natural and functionalized biochromophores. Anal Chem. 87(11):5614-9

Spletter, ML., Barz, C., Yeroslaviz, A., Schönbauer, C., Ferreira, IR., Sarov, M., Gerlach, D., Stark, A., Habermann, BH., Schnorrer, F. (2015) The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle. EMBO Rep. 16(2):178-91

Stampfel, G., Kazmar, T., Frank, O., Wienerroither, S., Reiter, F., Stark, A. (2015) Transcriptional regulators form diverse groups with context-dependent regulatory functions. Nature. 528(7580):147-51

Stevenson, P., Götz, C., Baiz, CR., Akerboom, J., Tokmakoff, A., Vaziri, A. (2015) Visualizing KcsA conformational changes upon ion binding by infrared spectroscopy and atomistic modeling. J Phys Chem B. 119(18):5824-31

Wedeh, G., Cerny-Reiterer, S., Eisenwort, G., Herrmann, H., Blatt, K., Hadzijusufovic, E., Sadovnik, I., Müllauer, L., Schwaab, J., Hoffmann, T., Bradner, JE., Radia, D., Sperr, WR., Hoermann, G., Reiter, A., Horny, HP., Zuber, J., Arock, M., Valent, P. (2015) Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia. Leukemia. 29(11):2230-7

Witkowski, MT., Cimmino, L., Hu, Y., Trimarchi, T., Tagoh, H., McKenzie, MD., Best, SA., Tuohey, L., Willson, TA., Nutt, SL., Busslinger, M., Aifantis, I., Smyth, GK., Dickins, RA. (2015) Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia. Leukemia. 29(6):1301-11

Yamaguchi, M., Yu, S., Qiao, R., Weissmann, F., Miller, DJ., VanderLinden, R., Brown, NG., Frye, JJ., Peters, JM., Schulman, BA. (2015) Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome. J Mol Biol. 427(8):1748-64

Yamano, T., Nedjic, J., Hinterberger, M., Steinert, M., Koser, S., Pinto, S., Gerdes, N., Lutgens, E., Ishimaru, N., Busslinger, M., Brors, B., Kyewski, B., Klein, L. (2015) Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. Immunity. 42(6):1048-61

Yeh, C., Coyaud, É., Bashkurov, M., van der Lelij, P., Cheung, SW., Peters, JM., Raught, B., Pelletier, L. (2015) The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression. Curr Biol. 25(17):2290-9

Zabidi, MA., Arnold, CD., Schernhuber, K., Pagani, M., Rath, M., Frank, O., Stark, A. (2015) Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation. Nature. 518(7540):556-9

Zhao, Z., Chen, CC., Rillahan, CD., Shen, R., Kitzing, T., McNerney, ME., Diaz-Flores, E., Zuber, J., Shannon, K., Le Beau, MM., Spector, MS., Kogan, SC., Lowe, SW. (2015) Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nat Genet. 47(5):539-43

2014

Ader, M., Tanaka, EM. (2014) Modeling human development in 3D culture. Curr Opin Cell Biol. 31:23-8

Arnold, CD., Gerlach, D., Spies, D., Matts, JA., Sytnikova, YA., Pagani, M., Lau, NC., Stark, A. (2014) Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution. Nat Genet. 46(7):685-92

Aschauer, DF., Rumpel, S. (2014) Measuring the functional organization of the neocortex at large and small scales. Neuron. 83(4):756-8

Bath, DE., Stowers, JR., Hörmann, D., Poehlmann, A., Dickson, BJ., Straw, AD. (2014) FlyMAD: rapid thermogenetic control of neuronal activity in freely walking Drosophila. Nat Methods. 11(7):756-62

Bidaye, SS., Machacek, C., Wu, Y., Dickson, BJ. (2014) Neuronal control of Drosophila walking direction. Science. 344(6179):97-101

Bots, M., Verbrugge, I., Martin, BP., Salmon, JM., Ghisi, M., Baker, A., Stanley, K., Shortt, J., Ossenkoppele, GJ., Zuber, J., Rappaport, AR., Atadja, P., Lowe, SW., Johnstone, RW. (2014) Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood. 123(9):1341-52

Breuss, M., Keays, DA. (2014) Microtubules and neurodevelopmental disease: the movers and the makers. Adv Exp Med Biol. 800:75-96

Brown, NG., Watson, ER., Weissmann, F., Jarvis, MA., VanderLinden, R., Grace, CR., Frye, JJ., Qiao, R., Dube, P., Petzold, G., Cho, SE., Alsharif, O., Bao, J., Davidson, IF., Zheng, JJ., Nourse, A., Kurinov, I., Peters, JM., Stark, H., Schulman, BA. (2014) Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly. Mol Cell. 56(2):246-60

Burgess, MR., Hwang, E., Firestone, AJ., Huang, T., Xu, J., Zuber, J., Bohin, N., Wen, T., Kogan, SC., Haigis, KM., Sampath, D., Lowe, S., Shannon, K., Li, Q. (2014) Preclinical efficacy of MEK inhibition in Nras-mutant AML. Blood. 124(26):3947-55

Busslinger, M., Tarakhovsky, A. (2014) Epigenetic control of immunity. Cold Spring Harb Perspect Biol. 6(6)

Cai, H., Haubensak, W., Anthony, TE., Anderson, DJ. (2014) Central amygdala PKC-δ(+) neurons mediate the influence of multiple anorexigenic signals. Nat Neurosci. 17(9):1240-8

Carido, M., Zhu, Y., Postel, K., Benkner, B., Cimalla, P., Karl, MO., Kurth, T., Paquet-Durand, F., Koch, E., Münch, TA., Tanaka, EM., Ader, M. (2014) Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation. Invest Ophthalmol Vis Sci. 55(8):5431-44

Chara, O., Tanaka, EM., Brusch, L. (2014) Mathematical modeling of regenerative processes. Curr Top Dev Biol. 108:283-317

Chen, C., Liu, Y., Rappaport, AR., Kitzing, T., Schultz, N., Zhao, Z., Shroff, AS., Dickins, RA., Vakoc, CR., Bradner, JE., Stock, W., LeBeau, MM., Shannon, KM., Kogan, S., Zuber, J., Lowe, SW. (2014) MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia. Cancer Cell. 25(5):652-65

Chin, AL., Lin, CY., Fu, TF., Dickson, BJ., Chiang, AS. (2014) Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum. J Comp Neurol. 522(17):3795-816

Cochella, L., Tursun, B., Hsieh, YW., Galindo, S., Johnston, RJ., Chuang, CF., Hobert, O. (2014) Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1. Genes Dev. 28(1):34-43

Dell, AI., Bender, JA., Branson, K., Couzin, ID., de Polavieja, GG., Noldus, LP., Pérez-Escudero, A., Perona, P., Straw, AD., Wikelski, M., Brose, U. (2014) Automated image-based tracking and its application in ecology. Trends Ecol Evol. 29(7):417-28

Demajo, S., Uribesalgo, I., Gutiérrez, A., Ballaré, C., Capdevila, S., Roth, M., Zuber, J., Martín-Caballero, J., Di Croce, L. (2014) ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia. Oncogene. 33(48):5501-10

Dikfidan, A., Loll, B., Zeymer, C., Magler, I., Clausen, T., Meinhart, A. (2014) RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1. Mol Cell. 54(6):975-86

Diogo, R., Murawala, P., Tanaka, EM. (2014) Is salamander hindlimb regeneration similar to that of the forelimb? Anatomical and morphogenetic analysis of hindlimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative and developmental studies. J Anat. 224(4):459-68

Diogo, R., Nacu, E., Tanaka, EM. (2014) Is salamander limb regeneration really perfect? Anatomical and morphogenetic analysis of forelimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative, developmental, and evolutionary studies. Anat Rec (Hoboken). 297(6):1076-89

Diogo, R., Tanaka, EM. (2014) Development of fore- and hindlimb muscles in GFP-transgenic axolotls: morphogenesis, the tetrapod bauplan, and new insights on the forelimb-hindlimb enigma. J Exp Zool B Mol Dev Evol. 322(2):106-27

Dorfer, V., Pichler, P., Stranzl, T., Stadlmann, J., Taus, T., Winkler, S., Mechtler, K. (2014) MS Amanda, a universal identification algorithm optimized for high accuracy tandem mass spectra. J Proteome Res. 13(8):3679-84

Dürnberger, G., Camurdanoglu, BZ., Tomschik, M., Schutzbier, M., Roitinger, E., Hudecz, O., Mechtler, K., Herbst, R. (2014) Global analysis of muscle-specific kinase signaling by quantitative phosphoproteomics. Mol Cell Proteomics. 13(8):1993-2003

Fei, JF., Schuez, M., Tazaki, A., Taniguchi, Y., Roensch, K., Tanaka, EM. (2014) CRISPR-mediated genomic deletion of Sox2 in the axolotl shows a requirement in spinal cord neural stem cell amplification during tail regeneration. Stem Cell Reports. 3(3):444-59

Feng, K., Palfreyman, MT., Häsemeyer, M., Talsma, A., Dickson, BJ. (2014) Ascending SAG neurons control sexual receptivity of Drosophila females. Neuron. 83(1):135-48

Fenk, LM., Poehlmann, A., Straw, AD. (2014) Asymmetric processing of visual motion for simultaneous object and background responses. Curr Biol. 24(24):2913-9

Fuller, SB., Straw, AD., Peek, MY., Murray, RM., Dickinson, MH. (2014) Flying Drosophila stabilize their vision-based velocity controller by sensing wind with their antennae. Proc Natl Acad Sci U S A. 111(13):E1182-91

Galán, JE., Lara-Tejero, M., Marlovits, TC., Wagner, S. (2014) Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells. Annu Rev Microbiol. 68:415-38

Hellerschmied, D., Clausen, T. (2014) Myosin chaperones. Curr Opin Struct Biol. 25:9-15

Hofbauer, HF., Schopf, FH., Schleifer, H., Knittelfelder, OL., Pieber, B., Rechberger, GN., Wolinski, H., Gaspar, ML., Kappe, CO., Stadlmann, J., Mechtler, K., Zenz, A., Lohner, K., Tehlivets, O., Henry, SA., Kohlwein, SD. (2014) Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids. Dev Cell. 29(6):729-39

Hornung, P., Troc, P., Malvezzi, F., Maier, M., Demianova, Z., Zimniak, T., Litos, G., Lampert, F., Schleiffer, A., Brunner, M., Mechtler, K., Herzog, F., Marlovits, TC., Westermann, S. (2014) A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A. J Cell Biol. 206(4):509-24

Howard, MF., Murakami, Y., Pagnamenta, AT., Daumer-Haas, C., Fischer, B., Hecht, J., Keays, DA., Knight, SJ., Kölsch, U., Krüger, U., Leiz, S., Maeda, Y., Mitchell, D., Mundlos, S., Phillips, JA., Robinson, PN., Kini, U., Taylor, JC., Horn, D., Kinoshita, T., Krawitz, PM. (2014) Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation. Am J Hum Genet. 94(2):278-87

Huang, CH., Lujambio, A., Zuber, J., Tschaharganeh, DF., Doran, MG., Evans, MJ., Kitzing, T., Zhu, N., de Stanchina, E., Sawyers, CL., Armstrong, SA., Lewis, JS., Sherr, CJ., Lowe, SW. (2014) CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma. Genes Dev. 28(16):1800-14

Huis in 't Veld, PJ., Herzog, F., Ladurner, R., Davidson, IF., Piric, S., Kreidl, E., Bhaskara, V., Aebersold, R., Peters, JM. (2014) Characterization of a DNA exit gate in the human cohesin ring. Science. 346(6212):968-72

Jurkin, J., Henkel, T., Nielsen, AF., Minnich, M., Popow, J., Kaufmann, T., Heindl, K., Hoffmann, T., Busslinger, M., Martinez, J. (2014) The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells. EMBO J. 33(24):2922-36

Karaca, E., Weitzer, S., Pehlivan, D., Shiraishi, H., Gogakos, T., Hanada, T., Jhangiani, SN., Wiszniewski, W., Withers, M., Campbell, IM., Erdin, S., Isikay, S., Franco, LM., Gonzaga-Jauregui, C., Gambin, T., Gelowani, V., Hunter, JV., Yesil, G., Koparir, E., Yilmaz, S., Brown, M., Briskin, D., Hafner, M., Morozov, P., Farazi, TA., Bernreuther, C., Glatzel, M., Trattnig, S., Friske, J., Kronnerwetter, C., Bainbridge, MN., Gezdirici, A., Seven, M., Muzny, DM., Boerwinkle, E., Ozen, M., Clausen, T., Tuschl, T., Yuksel, A., Hess, A., Gibbs, RA., Martinez, J., Penninger, JM., Lupski, JR. (2014) Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 157(3):636-50

Khattak, S., Murawala, P., Andreas, H., Kappert, V., Schuez, M., Sandoval-Guzmán, T., Crawford, K., Tanaka, EM. (2014) Optimized axolotl (Ambystoma mexicanum) husbandry, breeding, metamorphosis, transgenesis and tamoxifen-mediated recombination. Nat Protoc. 9(3):529-40

Khattak, S., Schuez, M., Richter, T., Knapp, D., Haigo, SL., Sandoval-Guzmán, T., Hradlikova, K., Duemmler, A., Kerney, R., Tanaka, EM. (2014) Germline Transgenic Methods for Tracking Cells and Testing Gene Function during Regeneration in the Axolotl. Stem Cell Reports. 2(2):243

Klose, CS., Flach, M., Möhle, L., Rogell, L., Hoyler, T., Ebert, K., Fabiunke, C., Pfeifer, D., Sexl, V., Fonseca-Pereira, D., Domingues, RG., Veiga-Fernandes, H., Arnold, SJ., Busslinger, M., Dunay, IR., Tanriver, Y., Diefenbach, A. (2014) Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages. Cell. 157(2):340-56

Köcher, T., Pichler, P., De Pra, M., Rieux, L., Swart, R., Mechtler, K. (2014) Development and performance evaluation of an ultralow flow nanoliquid chromatography-tandem mass spectrometry set-up. Proteomics. 14(17-18):1999-2007

Kvon, EZ., Kazmar, T., Stampfel, G., Yáñez-Cuna, JO., Pagani, M., Schernhuber, K., Dickson, BJ., Stark, A. (2014) Genome-scale functional characterization of Drosophila developmental enhancers in vivo. Nature. 512(7512):91-5

Ladurner, R., Bhaskara, V., Huis in 't Veld, PJ., Davidson, IF., Kreidl, E., Petzold, G., Peters, JM. (2014) Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation. Curr Biol. 24(19):2228-37

Liu, GJ., Cimmino, L., Jude, JG., Hu, Y., Witkowski, MT., McKenzie, MD., Kartal-Kaess, M., Best, SA., Tuohey, L., Liao, Y., Shi, W., Mullighan, CG., Farrar, MA., Nutt, SL., Smyth, GK., Zuber, J., Dickins, RA. (2014) Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia. Genes Dev. 28(12):1337-50

Malvezzi, F., Westermann, S. (2014) "Uno, nessuno e centomila": the different faces of the budding yeast kinetochore. Chromosoma. 123(5):447-57

Meier, M., Serbe, E., Maisak, MS., Haag, J., Dickson, BJ., Borst, A. (2014) Neural circuit components of the Drosophila OFF motion vision pathway. Curr Biol. 24(4):385-92

Meinhardt, A., Eberle, D., Tazaki, A., Ranga, A., Niesche, M., Wilsch-Bräuninger, M., Stec, A., Schackert, G., Lutolf, M., Tanaka, EM. (2014) 3D reconstitution of the patterned neural tube from embryonic stem cells. Stem Cell Reports. 3(6):987-99

Meireles-Filho, AC., Bardet, AF., Yáñez-Cuna, JO., Stampfel, G., Stark, A. (2014) cis-regulatory requirements for tissue-specific programs of the circadian clock. Curr Biol. 24(1):1-10

Mérai, Z., Chumak, N., García-Aguilar, M., Hsieh, TF., Nishimura, T., Schoft, VK., Bindics, J., Slusarz, L., Arnoux, S., Opravil, S., Mechtler, K., Zilberman, D., Fischer, RL., Tamaru, H. (2014) The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes. Proc Natl Acad Sci U S A. 111(45):16166-71

Mikl, M., Cowan, CR. (2014) Alternative 3' UTR selection controls PAR-5 homeostasis and cell polarity in C. elegans embryos. Cell Rep. 8(5):1380-90

Moczulska, KE., Pichler, P., Schutzbier, M., Schleiffer, A., Rumpel, S., Mechtler, K. (2014) Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation. J Proteome Res. 13(10):4310-24

Mueller, J., Pfanzelter, J., Winkler, C., Narita, A., Le Clainche, C., Nemethova, M., Carlier, MF., Maeda, Y., Welch, MD., Ohkawa, T., Schmeiser, C., Resch, GP., Small, JV. (2014) Electron tomography and simulation of baculovirus actin comet tails support a tethered filament model of pathogen propulsion. PLoS Biol. 12(1):e1001765

Muerdter, F., Stark, A. (2014) Genomics: Hiding in plain sight. Nature. 512(7515):374-5

Ngo, L., Haas, M., Qu, Z., Li, SS., Zenker, J., Teng, KS., Gunnersen, JM., Breuss, M., Habgood, M., Keays, DA., Heng, JI. (2014) TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons. Hum Mol Genet. 23(19):5147-58

Norell, D., Heuck, A., Tran-Thi, TA., Götzke, H., Jacob-Dubuisson, F., Clausen, T., Daley, DO., Braun, V., Müller, M., Fan, E. (2014) Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins. Nat Commun. 5:5396

Popow, J., Jurkin, J., Schleiffer, A., Martinez, J. (2014) Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors. Nature. 511(7507):104-7

Prevedel, R., Yoon, YG., Hoffmann, M., Pak, N., Wetzstein, G., Kato, S., Schrödel, T., Raskar, R., Zimmer, M., Boyden, ES., Vaziri, A. (2014) Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy. Nat Methods. 11(7):727-30

Qian, J., Wang, Q., Dose, M., Pruett, N., Kieffer-Kwon, KR., Resch, W., Liang, G., Tang, Z., Mathé, E., Benner, C., Dubois, W., Nelson, S., Vian, L., Oliveira, TY., Jankovic, M., Hakim, O., Gazumyan, A., Pavri, R., Awasthi, P., Song, B., Liu, G., Chen, L., Zhu, S., Feigenbaum, L., Staudt, L., Murre, C., Ruan, Y., Robbiani, DF., Pan-Hammarström, Q., Nussenzweig, MC., Casellas, R. (2014) B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity. Cell. 159(7):1524-37

Radics, J., Königsmaier, L., Marlovits, TC. (2014) Structure of a pathogenic type 3 secretion system in action. Nat Struct Mol Biol. 21(1):82-7

Rao, S., Tortola, L., Perlot, T., Wirnsberger, G., Novatchkova, M., Nitsch, R., Sykacek, P., Frank, L., Schramek, D., Komnenovic, V., Sigl, V., Aumayr, K., Schmauss, G., Fellner, N., Handschuh, S., Glösmann, M., Pasierbek, P., Schlederer, M., Resch, GP., Ma, Y., Yang, H., Popper, H., Kenner, L., Kroemer, G., Penninger, JM. (2014) A dual role for autophagy in a murine model of lung cancer. Nat Commun. 5:3056

Rembold, M., Ciglar, L., Yáñez-Cuna, JO., Zinzen, RP., Girardot, C., Jain, A., Welte, MA., Stark, A., Leptin, M., Furlong, EE. (2014) A conserved role for Snail as a potentiator of active transcription. Genes Dev. 28(2):167-81

Reuter, MS., Musante, L., Hu, H., Diederich, S., Sticht, H., Ekici, AB., Uebe, S., Wienker, TF., Bartsch, O., Zechner, U., Oppitz, C., Keleman, K., Jamra, RA., Najmabadi, H., Schweiger, S., Reis, A., Kahrizi, K. (2014) NDST1 missense mutations in autosomal recessive intellectual disability. Am J Med Genet A. 164A(11):2753-63

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, TW., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., Schirmacher, P., Zuber, J., Weiss, KH., Powers, S., Malek, NP., Eilers, M., Sipos, B., Lowe, SW., Geffers, R., Laufer, S., Zender, L. (2014) In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer. Nat Med. 20(10):1138-46

Sandoval-Guzmán, T., Wang, H., Khattak, S., Schuez, M., Roensch, K., Nacu, E., Tazaki, A., Joven, A., Tanaka, EM., Simon, A. (2014) Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species. Cell Stem Cell. 14(2):174-87

Sawicka, A., Hartl, D., Goiser, M., Pusch, O., Stocsits, RR., Tamir, IM., Mechtler, K., Seiser, C. (2014) H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress. Genome Res. 24(11):1808-20

Schmidt, A., Trentini, DB., Spiess, S., Fuhrmann, J., Ammerer, G., Mechtler, K., Clausen, T. (2014) Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response. Mol Cell Proteomics. 13(2):537-50

Schwickert, TA., Tagoh, H., Gültekin, S., Dakic, A., Axelsson, E., Minnich, M., Ebert, A., Werner, B., Roth, M., Cimmino, L., Dickins, RA., Zuber, J., Jaritz, M., Busslinger, M. (2014) Stage-specific control of early B cell development by the transcription factor Ikaros. Nat Immunol. 15(3):283-93

Seillet, C., Huntington, ND., Gangatirkar, P., Axelsson, E., Minnich, M., Brady, HJ., Busslinger, M., Smyth, MJ., Belz, GT., Carotta, S. (2014) Differential requirement for Nfil3 during NK cell development. J Immunol. 192(6):2667-76

Shlyueva, D., Stampfel, G., Stark, A. (2014) Transcriptional enhancers: from properties to genome-wide predictions. Nat Rev Genet. 15(4):272-86

Shlyueva, D., Stelzer, C., Gerlach, D., Yáñez-Cuna, JO., Rath, M., Boryń, LM., Arnold, CD., Stark, A. (2014) Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin. Mol Cell. 54(1):180-92

Shodhan, A., Lukaszewicz, A., Novatchkova, M., Loidl, J. (2014) Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of Tetrahymena. Genetics. 198(3):983-93

Stowers, JR., Fuhrmann, A., Hofbauer, M., Streinzer, M., Schmid, A., Dickinson, MH., Straw, AD. (2014) Reverse Engineering Animal Vision with Virtual Reality and Genetics. Computer. 14(190):38–45

Tomanov, K., Zeschmann, A., Hermkes, R., Eifler, K., Ziba, I., Grieco, M., Novatchkova, M., Hofmann, K., Hesse, H., Bachmair, A. (2014) Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism. Plant Cell. 26(11):4547-60

Trentini, DB., Fuhrmann, J., Mechtler, K., Clausen, T. (2014) Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap. Mol Cell Proteomics. 13(8):1953-64

Valent, P., Zuber, J. (2014) BRD4: a BET(ter) target for the treatment of AML? Cell Cycle. 13(5):689-90

van der Lelij, P., Stocsits, RR., Ladurner, R., Petzold, G., Kreidl, E., Koch, B., Schmitz, J., Neumann, B., Ellenberg, J., Peters, JM. (2014) SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs. EMBO J. 33(22):2643-58

von Philipsborn, AC., Jörchel, S., Tirian, L., Demir, E., Morita, T., Stern, DL., Dickson, BJ. (2014) Cellular and behavioral functions of fruitless isoforms in Drosophila courtship. Curr Biol. 24(3):242-51

Waidmann, S., Kusenda, B., Mayerhofer, J., Mechtler, K., Jonak, C. (2014) A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Plant Cell. 26(11):4328-44

Walzer, M., Pernas, LE., Nasso, S., Bittremieux, W., Nahnsen, S., Kelchtermans, P., Pichler, P., van den Toorn, HW., Staes, A., Vandenbussche, J., Mazanek, M., Taus, T., Scheltema, RA., Kelstrup, CD., Gatto, L., van Breukelen, B., Aiche, S., Valkenborg, D., Laukens, K., Lilley, KS., Olsen, JV., Heck, AJ., Mechtler, K., Aebersold, R., Gevaert, K., Vizcaíno, JA., Hermjakob, H., Kohlbacher, O., Martens, L. (2014) qcML: an exchange format for quality control metrics from mass spectrometry experiments. Mol Cell Proteomics. 13(8):1905-13

Wang, Q., Oliveira, T., Jankovic, M., Silva, IT., Hakim, O., Yao, K., Gazumyan, A., Mayer, CT., Pavri, R., Casellas, R., Nussenzweig, MC., Robbiani, DF. (2014) Epigenetic targeting of activation-induced cytidine deaminase. Proc Natl Acad Sci U S A. 111(52):18667-72

Wienerroither, S., Rauch, I., Rosebrock, F., Jamieson, AM., Bradner, J., Muhar, M., Zuber, J., Müller, M., Decker, T. (2014) Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins. Mol Cell Biol. 34(3):415-27

Wirnsberger, G., Zwolanek, F., Stadlmann, J., Tortola, L., Liu, SW., Perlot, T., Järvinen, P., Dürnberger, G., Kozieradzki, I., Sarao, R., De Martino, A., Boztug, K., Mechtler, K., Kuchler, K., Klein, C., Elling, U., Penninger, JM. (2014) Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense. Nat Genet. 46(9):1028-33

Yáñez-Cuna, JO., Arnold, CD., Stampfel, G., Boryń, LM., Gerlach, D., Rath, M., Stark, A. (2014) Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features. Genome Res. 24(7):1147-56

Yapici, N., Zimmer, M., Domingos, AI. (2014) Cellular and molecular basis of decision-making. EMBO Rep. 15(10):1023-35

Yuan, TL., Fellmann, C., Lee, CS., Ritchie, CD., Thapar, V., Lee, LC., Hsu, DJ., Grace, D., Carver, JO., Zuber, J., Luo, J., McCormick, F., Lowe, SW. (2014) Development of siRNA payloads to target KRAS-mutant cancer. Cancer Discov. 4(10):1182-97

Zhao, X., Chen, A., Yan, X., Zhang, Y., He, F., Hayashi, Y., Dong, Y., Rao, Y., Li, B., Conway, RM., Maiques-Diaz, A., Elf, SE., Huang, N., Zuber, J., Xiao, Z., Tse, W., Tenen, DG., Wang, Q., Chen, W., Mulloy, JC., Nimer, SD., Huang, G. (2014) Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal. Blood. 123(11):1729-38

2013

Arnold, CD., Gerlach, D., Stelzer, C., Boryń, ŁM., Rath, M., Stark, A. (2013) Genome-wide quantitative enhancer activity maps identified by STARR-seq. Science. 339(6123):1074-7

Aschauer, DF., Kreuz, S., Rumpel, S. (2013) Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain. PLoS One. 8(9):e76310

Bardet, AF., Steinmann, J., Bafna, S., Knoblich, JA., Zeitlinger, J., Stark, A. (2013) Identification of transcription factor binding sites from ChIP-seq data at high resolution. Bioinformatics. 29(21):2705-13

Bathellier, B., Tee, SP., Hrovat, C., Rumpel, S. (2013) A multiplicative reinforcement learning model capturing learning dynamics and interindividual variability in mice. Proc Natl Acad Sci U S A. 110(49):19950-5

Cabral, G., Sans, SS., Cowan, CR., Dammermann, A. (2013) Multiple mechanisms contribute to centriole separation in C. elegans. Curr Biol. 23(14):1380-7

Censi, A., Straw, AD., Sayaman, RW., Murray, RM., Dickinson, MH. (2013) Discriminating external and internal causes for heading changes in freely flying Drosophila. PLoS Comput Biol. 9(2):e1002891

Conti, V., Carabalona, A., Pallesi-Pocachard, E., Parrini, E., Leventer, RJ., Buhler, E., McGillivray, G., Michel, FJ., Striano, P., Mei, D., Watrin, F., Lise, S., Pagnamenta, AT., Taylor, JC., Kini, U., Clayton-Smith, J., Novara, F., Zuffardi, O., Dobyns, WB., Scheffer, IE., Robertson, SP., Berkovic, SF., Represa, A., Keays, DA., Cardoso, C., Guerrini, R. (2013) Periventricular heterotopia in 6q terminal deletion syndrome: role of the C6orf70 gene. Brain. 136(Pt 11):3378-94

Earnshaw, WC., Allshire, RC., Black, BE., Bloom, K., Brinkley, BR., Brown, W., Cheeseman, IM., Choo, KH., Copenhaver, GP., Deluca, JG., Desai, A., Diekmann, S., Erhardt, S., Fitzgerald-Hayes, M., Foltz, D., Fukagawa, T., Gassmann, R., Gerlich, DW., Glover, DM., Gorbsky, GJ., Harrison, SC., Heun, P., Hirota, T., Jansen, LE., Karpen, G., Kops, GJ., Lampson, MA., Lens, SM., Losada, A., Luger, K., Maiato, H., Maddox, PS., Margolis, RL., Masumoto, H., McAinsh, AD., Mellone, BG., Meraldi, P., Musacchio, A., Oegema, K., O'Neill, RJ., Salmon, ED., Scott, KC., Straight, AF., Stukenberg, PT., Sullivan, BA., Sullivan, KF., Sunkel, CE., Swedlow, JR., Walczak, CE., Warburton, PE., Westermann, S., Willard, HF., Wordeman, L., Yanagida, M., Yen, TJ., Yoda, K., Cleveland, DW. (2013) Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 21(2):101-6

Ebert, A., Medvedovic, J., Tagoh, H., Schwickert, TA., Busslinger, M. (2013) Control of antigen receptor diversity through spatial regulation of V(D)J recombination. Cold Spring Harb Symp Quant Biol. 78:11-21

Elsayad, K., Urich, A., Tan, PS., Nemethova, M., Small, JV., Unterrainer, K., Heinze, KG. (2013) Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates. Proc Natl Acad Sci U S A. 110(50):20069-74

Esteghamat, F., Gillemans, N., Bilic, I., van den Akker, E., Cantù, I., van Gent, T., Klingmüller, U., van Lom, K., von Lindern, M., Grosveld, F., Bryn van Dijk, T., Busslinger, M., Philipsen, S. (2013) Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice. Blood. 121(13):2553-62

Fellmann, C., Hoffmann, T., Sridhar, V., Hopfgartner, B., Muhar, M., Roth, M., Lai, DY., Barbosa, IA., Kwon, JS., Guan, Y., Sinha, N., Zuber, J. (2013) An optimized microRNA backbone for effective single-copy RNAi. Cell Rep. 5(6):1704-13

Fischer, RM., Fontinha, BM., Kirchmaier, S., Steger, J., Bloch, S., Inoue, D., Panda, S., Rumpel, S., Tessmar-Raible, K. (2013) Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain. PLoS Biol. 11(6):e1001585

Frelin, C., Herrington, R., Janmohamed, S., Barbara, M., Tran, G., Paige, CJ., Benveniste, P., Zuñiga-Pflücker, JC., Souabni, A., Busslinger, M., Iscove, NN. (2013) GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nat Immunol. 14(10):1037-44

Frese, CK., Zhou, H., Taus, T., Altelaar, AF., Mechtler, K., Heck, AJ., Mohammed, S. (2013) Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD). J Proteome Res. 12(3):1520-5

Frye, JJ., Brown, NG., Petzold, G., Watson, ER., Grace, CR., Nourse, A., Jarvis, MA., Kriwacki, RW., Peters, JM., Stark, H., Schulman, BA. (2013) Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown. Nat Struct Mol Biol. 20(7):827-35

Fuhrmann, J., Mierzwa, B., Trentini, DB., Spiess, S., Lehner, A., Charpentier, E., Clausen, T. (2013) Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep. 3(6):1832-9

Gazda, L., Pokrzywa, W., Hellerschmied, D., Löwe, T., Forné, I., Mueller-Planitz, F., Hoppe, T., Clausen, T. (2013) The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans. Cell. 152(1-2):183-95

Gramstrup Petersen, J., Rojo Romanos, T., Juozaityte, V., Redo Riveiro, A., Hums, I., Traunmüller, L., Zimmer, M., Pocock, R. (2013) EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans. PLoS Genet. 9(5):e1003511

Hanada, T., Weitzer, S., Mair, B., Bernreuther, C., Wainger, BJ., Ichida, J., Hanada, R., Orthofer, M., Cronin, SJ., Komnenovic, V., Minis, A., Sato, F., Mimata, H., Yoshimura, A., Tamir, I., Rainer, J., Kofler, R., Yaron, A., Eggan, KC., Woolf, CJ., Glatzel, M., Herbst, R., Martinez, J., Penninger, JM. (2013) CLP1 links tRNA metabolism to progressive motor-neuron loss. Nature. 495(7442):474-80

Hwang, SS., Kim, YU., Lee, S., Jang, SW., Kim, MK., Koh, BH., Lee, W., Kim, J., Souabni, A., Busslinger, M., Lee, GR. (2013) Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation. Proc Natl Acad Sci U S A. 110(1):276-81

Ivanov, AR., Colangelo, CM., Dufresne, CP., Friedman, DB., Lilley, KS., Mechtler, K., Phinney, BS., Rose, KL., Rudnick, PA., Searle, BC., Shaffer, SA., Weintraub, ST. (2013) Interlaboratory studies and initiatives developing standards for proteomics. Proteomics. 13(6):904-9

Jászai, J., Graupner, S., Tanaka, EM., Funk, RH., Huttner, WB., Brand, M., Corbeil, D. (2013) Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain. PLoS One. 8(5):e63457

Jüschke, C., Dohnal, I., Pichler, P., Harzer, H., Swart, R., Ammerer, G., Mechtler, K., Knoblich, JA. (2013) Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol. 14(11):r133

Kazmar, T., Kvon EZ., Stark, A., Lampert, CH.. (2013) Drosophila Embryo Stage Annotation using Label Propagation International Conference on Computer Vision (ICCV). Springer. Dec:1089–1096

Khattak, S., Sandoval-Guzmán, T., Stanke, N., Protze, S., Tanaka, EM., Lindemann, D. (2013) Foamy virus for efficient gene transfer in regeneration studies. BMC Dev Biol. 13:17

Knapp, D., Schulz, H., Rascon, CA., Volkmer, M., Scholz, J., Nacu, E., Le, M., Novozhilov, S., Tazaki, A., Protze, S., Jacob, T., Hubner, N., Habermann, B., Tanaka, EM. (2013) Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program. PLoS One. 8(5):e61352

Kollmann, K., Heller, G., Schneckenleithner, C., Warsch, W., Scheicher, R., Ott, RG., Schäfer, M., Fajmann, S., Schlederer, M., Schiefer, AI., Reichart, U., Mayerhofer, M., Hoeller, C., Zöchbauer-Müller, S., Kerjaschki, D., Bock, C., Kenner, L., Hoefler, G., Freissmuth, M., Green, AR., Moriggl, R., Busslinger, M., Malumbres, M., Sexl, V. (2013) A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis. Cancer Cell. 24(2):167-81

Kragl, M., Roensch, K., Nüsslein, I., Tazaki, A., Taniguchi, Y., Tarui, H., Hayashi, T., Agata, K., Tanaka, EM. (2013) Muscle and connective tissue progenitor populations show distinct Twist1 and Twist3 expression profiles during axolotl limb regeneration. Dev Biol. 373(1):196-204

Lampert, F., Mieck, C., Alushin, GM., Nogales, E., Westermann, S. (2013) Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes. J Cell Biol. 200(1):21-30

Lauwers, M., Pichler, P., Edelman, NB., Resch, GP., Ushakova, L., Salzer, MC., Heyers, D., Saunders, M., Shaw, J., Keays, DA. (2013) An iron-rich organelle in the cuticular plate of avian hair cells. Curr Biol. 23(10):924-9

Lin, CY., Chuang, CC., Hua, TE., Chen, CC., Dickson, BJ., Greenspan, RJ., Chiang, AS. (2013) A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain. Cell Rep. 3(5):1739-53

Lin, HH., Chu, LA., Fu, TF., Dickson, BJ., Chiang, AS. (2013) Parallel neural pathways mediate CO2 avoidance responses in Drosophila. Science. 340(6138):1338-41

Mair, B., Popow, J., Mechtler, K., Weitzer, S., Martinez, J. (2013) Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components. Biochem Soc Trans. 41(4):831-7

Maisak, MS., Haag, J., Ammer, G., Serbe, E., Meier, M., Leonhardt, A., Schilling, T., Bahl, A., Rubin, GM., Nern, A., Dickson, BJ., Reiff, DF., Hopp, E., Borst, A. (2013) A directional tuning map of Drosophila elementary motion detectors. Nature. 500(7461):212-6

Malvezzi, F., Litos, G., Schleiffer, A., Heuck, A., Mechtler, K., Clausen, T., Westermann, S. (2013) A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J. 32(3):409-23

Masson, F., Minnich, M., Olshansky, M., Bilic, I., Mount, AM., Kallies, A., Speed, TP., Busslinger, M., Nutt, SL., Belz, GT. (2013) Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation. J Immunol. 190(9):4585-94

Mastny, M., Heuck, A., Kurzbauer, R., Heiduk, A., Boisguerin, P., Volkmer, R., Ehrmann, M., Rodrigues, CD., Rudner, DZ., Clausen, T. (2013) CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis. Cell. 155(3):647-58

Medvedovic, J., Ebert, A., Tagoh, H., Tamir, IM., Schwickert, TA., Novatchkova, M., Sun, Q., Huis In 't Veld, PJ., Guo, C., Yoon, HS., Denizot, Y., Holwerda, SJ., de Laat, W., Cogné, M., Shi, Y., Alt, FW., Busslinger, M. (2013) Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity. 39(2):229-44

Moczulska, KE., Tinter-Thiede, J., Peter, M., Ushakova, L., Wernle, T., Bathellier, B., Rumpel, S. (2013) Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall. Proc Natl Acad Sci U S A. 110(45):18315-20

Moruz, L., Pichler, P., Stranzl, T., Mechtler, K., Käll, L. (2013) Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics. Anal Chem. 85(16):7777-85

Nacu, E., Glausch, M., Le, HQ., Damanik, FF., Schuez, M., Knapp, D., Khattak, S., Richter, T., Tanaka, EM. (2013) Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl. Development. 140(3):513-8

Nishiyama, T., Sykora, MM., Huis in 't Veld, PJ., Mechtler, K., Peters, JM. (2013) Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin. Proc Natl Acad Sci U S A. 110(33):13404-9

Ohtsuka, N., Badurek, S., Busslinger, M., Benes, FM., Minichiello, L., Rudolph, U. (2013) GABAergic neurons regulate lateral ventricular development via transcription factor Pax5. Genesis. 51(4):234-45

Osman, K., Roitinger, E., Yang, J., Armstrong, S., Mechtler, K., Franklin, FC. (2013) Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics. Methods Mol Biol. 990:215-26

Peter, M., Bathellier, B., Fontinha, B., Pliota, P., Haubensak, W., Rumpel, S. (2013) Transgenic mouse models enabling photolabeling of individual neurons in vivo. PLoS One. 8(4):e62132

Reiter, W., Klopf, E., De Wever, V., Anrather, D., Petryshyn, A., Roetzer, A., Niederacher, G., Roitinger, E., Dohnal, I., Görner, W., Mechtler, K., Brocard, C., Schüller, C., Ammerer, G. (2013) Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment. Mol Cell Biol. 33(5):1057-72

Roensch, K., Tazaki, A., Chara, O., Tanaka, EM. (2013) Progressive specification rather than intercalation of segments during limb regeneration. Science. 342(6164):1375-9

Schmidt, A., Ammerer, G., Mechtler, K. (2013) Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho-site localization. Proteomics. 13(6):945-54

Schrödel, T., Prevedel, R., Aumayr, K., Zimmer, M., Vaziri, A. (2013) Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light. Nat Methods. 10(10):1013-20

Shi, J., Wang, E., Zuber, J., Rappaport, A., Taylor, M., Johns, C., Lowe, SW., Vakoc, CR. (2013) The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia. Oncogene. 32(7):930-8

Shi, J., Whyte, WA., Zepeda-Mendoza, CJ., Milazzo, JP., Shen, C., Roe, JS., Minder, JL., Mercan, F., Wang, E., Eckersley-Maslin, MA., Campbell, AE., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, RG., Wigler, MH., Blobel, GA., Zuber, J., Spector, DL., Young, RA., Vakoc, CR. (2013) Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes Dev. 27(24):2648-62

Simon, A., Tanaka, EM. (2013) Limb regeneration. Wiley Interdiscip Rev Dev Biol. 2(2):291-300

Simunovic, M., Mim, C., Marlovits, TC., Resch, G., Unger, VM., Voth, GA. (2013) Protein-mediated transformation of lipid vesicles into tubular networks. Biophys J. 105(3):711-9

Skora, S., Zimmer, M. (2013) Life(span) in balance: oxygen fuels a sophisticated neural network for lifespan homeostasis in C. elegans. EMBO J. 32(11):1499-501

Stark, A. (2013) Regulatory Genomics - Decoding Drosophila Regulatory Sequences. Biomed Tech (Berl).

Stewart, R., Rascón, CA., Tian, S., Nie, J., Barry, C., Chu, LF., Ardalani, H., Wagner, RJ., Probasco, MD., Bolin, JM., Leng, N., Sengupta, S., Volkmer, M., Habermann, B., Tanaka, EM., Thomson, JA., Dewey, CN. (2013) Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema. PLoS Comput Biol. 9(3):e1002936

Tedeschi, A., Wutz, G., Huet, S., Jaritz, M., Wuensche, A., Schirghuber, E., Davidson, IF., Tang, W., Cisneros, DA., Bhaskara, V., Nishiyama, T., Vaziri, A., Wutz, A., Ellenberg, J., Peters, JM. (2013) Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature. 501(7468):564-8

Treiber, CD., Salzer, M., Breuss, M., Ushakova, L., Lauwers, M., Edelman, N., Keays, DA. (2013) High resolution anatomical mapping confirms the absence of a magnetic sense system in the rostral upper beak of pigeons. Commun Integr Biol. 6(4):e24859

Watkins-Chow, DE., Cooke, J., Pidsley, R., Edwards, A., Slotkin, R., Leeds, KE., Mullen, R., Baxter, LL., Campbell, TG., Salzer, MC., Biondini, L., Gibney, G., Phan Dinh Tuy, F., Chelly, J., Morris, HD., Riegler, J., Lythgoe, MF., Arkell, RM., Loreni, F., Flint, J., Pavan, WJ., Keays, DA. (2013) Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes. PLoS Genet. 9(1):e1003094

Westermann, S., Schleiffer, A. (2013) Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans. Trends Cell Biol. 23(6):260-9

Yáñez-Cuna, JO., Kvon, EZ., Stark, A. (2013) Deciphering the transcriptional cis-regulatory code. Trends Genet. 29(1):11-22

Zantke, J., Ishikawa-Fujiwara, T., Arboleda, E., Lohs, C., Schipany, K., Hallay, N., Straw, AD., Todo, T., Tessmar-Raible, K. (2013) Circadian and circalunar clock interactions in a marine annelid. Cell Rep. 5(1):99-113

Zhu, Y., Carido, M., Meinhardt, A., Kurth, T., Karl, MO., Ader, M., Tanaka, EM. (2013) Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium. PLoS One. 8(1):e54552

2012

Bathellier, B., Ushakova, L., Rumpel, S. (2012) Discrete neocortical dynamics predict behavioral categorization of sounds. Neuron. 76(2):435-49

Berger, C., Harzer, H., Burkard, TR., Steinmann, J., van der Horst, S., Laurenson, AS., Novatchkova, M., Reichert, H., Knoblich, JA. (2012) FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal. Cell Rep. 2(2):407-18

Bergerson, RJ., Collier, LS., Sarver, AL., Been, RA., Lugthart, S., Diers, MD., Zuber, J., Rappaport, AR., Nixon, MJ., Silverstein, KA., Fan, D., Lamblin, AF., Wolff, L., Kersey, JH., Delwel, R., Lowe, SW., O'Sullivan, MG., Kogan, SC., Adams, DJ., Largaespada, DA. (2012) An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model. Blood. 119(19):4512-23

Bienkowska, D., Cowan, CR. (2012) Centrosomes can initiate a polarity axis from any position within one-cell C. elegans embryos. Curr Biol. 22(7):583-9

Bossinger, O., Cowan, CR. (2012) Methods in cell biology: analysis of cell polarity in C. elegans embryos. Methods Cell Biol. 107:207-38

Breuss, M., Heng, JI., Poirier, K., Tian, G., Jaglin, XH., Qu, Z., Braun, A., Gstrein, T., Ngo, L., Haas, M., Bahi-Buisson, N., Moutard, ML., Passemard, S., Verloes, A., Gressens, P., Xie, Y., Robson, KJ., Rani, DS., Thangaraj, K., Clausen, T., Chelly, J., Cowan, NJ., Keays, DA. (2012) Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2(6):1554-62

Chelysheva, L., Vezon, D., Chambon, A., Gendrot, G., Pereira, L., Lemhemdi, A., Vrielynck, N., Le Guin, S., Novatchkova, M., Grelon, M. (2012) The Arabidopsis HEI10 is a new ZMM protein related to Zip3. PLoS Genet. 8(7):e1002799

Dal Santo, S., Stampfl, H., Krasensky, J., Kempa, S., Gibon, Y., Petutschnig, E., Rozhon, W., Heuck, A., Clausen, T., Jonak, C. (2012) Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis. Plant Cell. 24(8):3380-92

Demczuk, A., Gauthier, MG., Veras, I., Kosiyatrakul, S., Schildkraut, CL., Busslinger, M., Bechhoefer, J., Norio, P. (2012) Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment. PLoS Biol. 10(7):e1001360

Diogo, R., Tanaka, EM. (2012) Anatomy of the pectoral and forelimb muscles of wildtype and green fluorescent protein-transgenic axolotls and comparison with other tetrapods including humans: a basis for regenerative, evolutionary and developmental studies. J Anat. 221(6):622-35

Dow, LE., Premsrirut, PK., Zuber, J., Fellmann, C., McJunkin, K., Miething, C., Park, Y., Dickins, RA., Hannon, GJ., Lowe, SW. (2012) A pipeline for the generation of shRNA transgenic mice. Nat Protoc. 7(2):374-93

Epperlein, HH., Khattak, S., Knapp, D., Tanaka, EM., Malashichev, YB. (2012) Neural crest does not contribute to the neck and shoulder in the axolotl (Ambystoma mexicanum). PLoS One. 7(12):e52244

Ferdous, M., Higgins, JD., Osman, K., Lambing, C., Roitinger, E., Mechtler, K., Armstrong, SJ., Perry, R., Pradillo, M., Cuñado, N., Franklin, FC. (2012) Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3. PLoS Genet. 8(2):e1002507

Fernandez-Rodriguez, J., Marlovits, TC. (2012) Induced heterodimerization and purification of two target proteins by a synthetic coiled-coil tag. Protein Sci. 21(4):511-9

Glaser, SP., Lee, EF., Trounson, E., Bouillet, P., Wei, A., Fairlie, WD., Izon, DJ., Zuber, J., Rappaport, AR., Herold, MJ., Alexander, WS., Lowe, SW., Robb, L., Strasser, A. (2012) Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. Genes Dev. 26(2):120-5

Herrmann, H., Blatt, K., Shi, J., Gleixner, KV., Cerny-Reiterer, S., Müllauer, L., Vakoc, CR., Sperr, WR., Horny, HP., Bradner, JE., Zuber, J., Valent, P. (2012) Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML. Oncotarget. 3(12):1588-99

Hnisz, D., Bardet, AF., Nobile, CJ., Petryshyn, A., Glaser, W., Schöck, U., Stark, A., Kuchler, K. (2012) A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis. PLoS Genet. 8(12):e1003118

Hoyler, T., Klose, CS., Souabni, A., Turqueti-Neves, A., Pfeifer, D., Rawlins, EL., Voehringer, D., Busslinger, M., Diefenbach, A. (2012) The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity. 37(4):634-48

Jafari, S., Alkhori, L., Schleiffer, A., Brochtrup, A., Hummel, T., Alenius, M. (2012) Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression. PLoS Biol. 10(3):e1001280

Keleman, K., Vrontou, E., Krüttner, S., Yu, JY., Kurtovic-Kozaric, A., Dickson, BJ. (2012) Dopamine neurons modulate pheromone responses in Drosophila courtship learning. Nature. 489(7414):145-9

Knapp, D., Tanaka, EM. (2012) Regeneration and reprogramming. Curr Opin Genet Dev. 22(5):485-93

Köcher, T., Pichler, P., Swart, R., Mechtler, K. (2012) Analysis of protein mixtures from whole-cell extracts by single-run nanoLC-MS/MS using ultralong gradients. Nat Protoc. 7(5):882-90

Kosarewicz, A., Königsmaier, L., Marlovits, TC. (2012) The blueprint of the type-3 injectisome. Philos Trans R Soc Lond B Biol Sci. 367(1592):1140-54

Krüttner, S., Stepien, B., Noordermeer, JN., Mommaas, MA., Mechtler, K., Dickson, BJ., Keleman, K. (2012) Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain. Neuron. 76(2):383-95

Kvon, EZ., Stampfel, G., Yáñez-Cuna, JO., Dickson, BJ., Stark, A. (2012) HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev. 26(9):908-13

Lai, JS., Lo, SJ., Dickson, BJ., Chiang, AS. (2012) Auditory circuit in the Drosophila brain. Proc Natl Acad Sci U S A. 109(7):2607-12

Latos, PA., Pauler, FM., Koerner, MV., Şenergin, HB., Hudson, QJ., Stocsits, RR., Allhoff, W., Stricker, SH., Klement, RM., Warczok, KE., Aumayr, K., Pasierbek, P., Barlow, DP. (2012) Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing. Science. 338(6113):1469-72

Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, HR. (2012) Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nat Struct Mol Biol. 19(2):152-7

Mattarollo, SR., West, AC., Steegh, K., Duret, H., Paget, C., Martin, B., Matthews, GM., Shortt, J., Chesi, M., Bergsagel, PL., Bots, M., Zuber, J., Lowe, SW., Johnstone, RW., Smyth, MJ. (2012) NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma. Blood. 120(15):3019-29

McHedlishvili, L., Mazurov, V., Grassme, KS., Goehler, K., Robl, B., Tazaki, A., Roensch, K., Duemmler, A., Tanaka, EM. (2012) Reconstitution of the central and peripheral nervous system during salamander tail regeneration. Proc Natl Acad Sci U S A. 109(34):E2258-66

McHedlishvili, L., Mazurov, V., Tanaka, EM. (2012) Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres. Methods Mol Biol. 916:197-202

Neely, GG., Rao, S., Costigan, M., Mair, N., Racz, I., Milinkeviciute, G., Meixner, A., Nayanala, S., Griffin, RS., Belfer, I., Dai, F., Smith, S., Diatchenko, L., Marengo, S., Haubner, BJ., Novatchkova, M., Gibson, D., Maixner, W., Pospisilik, JA., Hirsch, E., Whishaw, IQ., Zimmer, A., Gupta, V., Sasaki, J., Kanaho, Y., Sasaki, T., Kress, M., Woolf, CJ., Penninger, JM. (2012) Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception. PLoS Genet. 8(12):e1003071

Novatchkova, M., Tomanov, K., Hofmann, K., Stuible, HP., Bachmair, A. (2012) Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison. New Phytol. 195(1):23-31

Pagnamenta, AT., Lise, S., Harrison, V., Stewart, H., Jayawant, S., Quaghebeur, G., Deng, AT., Murphy, VE., Sadighi Akha, E., Rimmer, A., Mathieson, I., Knight, SJ., Kini, U., Taylor, JC., Keays, DA. (2012) Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies. J Hum Genet. 57(1):70-2

Pagnamenta, AT., Murray, JE., Yoon, G., Sadighi Akha, E., Harrison, V., Bicknell, LS., Ajilogba, K., Stewart, H., Kini, U., Taylor, JC., Keays, DA., Jackson, AP., Knight, SJ. (2012) A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss. Am J Med Genet A. 158A(10):2577-82

Peter, M., Scheuch, H., Burkard, TR., Tinter, J., Wernle, T., Rumpel, S. (2012) Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds. Genes Brain Behav. 11(3):314-24

Peters, JM. (2012) The many functions of cohesin--different rings to rule them all? EMBO J. 31(9):2061-3

Peters, JM., Nishiyama, T. (2012) Sister chromatid cohesion. Cold Spring Harb Perspect Biol. 4(11)

Pichler, P., Mazanek, M., Dusberger, F., Weilnböck, L., Huber, CG., Stingl, C., Luider, TM., Straube, WL., Köcher, T., Mechtler, K. (2012) SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments. J Proteome Res. 11(11):5540-7

Plath, K., Srivastava, D., Alvarez-Buylla, A., Tanaka, EM., Kriegstein, AR. (2012) Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 11(5):607-14

Popow, J., Schleiffer, A., Martinez, J. (2012) Diversity and roles of (t)RNA ligases. Cell Mol Life Sci. 69(16):2657-70

Protze, S., Khattak, S., Poulet, C., Lindemann, D., Tanaka, EM., Ravens, U. (2012) A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells. J Mol Cell Cardiol. 53(3):323-32

Revilla-I-Domingo, R., Bilic, I., Vilagos, B., Tagoh, H., Ebert, A., Tamir, IM., Smeenk, L., Trupke, J., Sommer, A., Jaritz, M., Busslinger, M. (2012) The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis. EMBO J. 31(14):3130-46

Schleiffer, A., Maier, M., Litos, G., Lampert, F., Hornung, P., Mechtler, K., Westermann, S. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol. 14(6):604-13

Tanaka, EM. (2012) Regenerative biology: Skin, heal thyself. Nature. 489(7417):508-10

Tapia, N., Reinhardt, P., Duemmler, A., Wu, G., Araúzo-Bravo, MJ., Esch, D., Greber, B., Cojocaru, V., Rascon, CA., Tazaki, A., Kump, K., Voss, R., Tanaka, EM., Schöler, HR. (2012) Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nat Commun. 3:1279

Tennstaedt, A., Pöpsel, S., Truebestein, L., Hauske, P., Brockmann, A., Schmidt, N., Irle, I., Sacca, B., Niemeyer, CM., Brandt, R., Ksiezak-Reding, H., Tirniceriu, AL., Egensperger, R., Baldi, A., Dehmelt, L., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2012) Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates. J Biol Chem. 287(25):20931-41

Toda, H., Zhao, X., Dickson, BJ. (2012) The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior. Cell Rep. 1(6):599-607

Treiber, CD., Salzer, MC., Riegler, J., Edelman, N., Sugar, C., Breuss, M., Pichler, P., Cadiou, H., Saunders, M., Lythgoe, M., Shaw, J., Keays, DA. (2012) Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons. Nature. 484(7394):367-70

Uzunova, K., Dye, BT., Schutz, H., Ladurner, R., Petzold, G., Toyoda, Y., Jarvis, MA., Brown, NG., Poser, I., Novatchkova, M., Mechtler, K., Hyman, AA., Stark, H., Schulman, BA., Peters, JM. (2012) APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol. 19(11):1116-23

Valent, P., Bonnet, D., De Maria, R., Lapidot, T., Copland, M., Melo, JV., Chomienne, C., Ishikawa, F., Schuringa, JJ., Stassi, G., Huntly, B., Herrmann, H., Soulier, J., Roesch, A., Schuurhuis, GJ., Wöhrer, S., Arock, M., Zuber, J., Cerny-Reiterer, S., Johnsen, HE., Andreeff, M., Eaves, C. (2012) Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer. 12(11):767-75

van der Harst, P., Zhang, W., Mateo Leach, I., Rendon, A., Verweij, N., Sehmi, J., Paul, DS., Elling, U., Allayee, H., Li, X., Radhakrishnan, A., Tan, ST., Voss, K., Weichenberger, CX., Albers, CA., Al-Hussani, A., Asselbergs, FW., Ciullo, M., Danjou, F., Dina, C., Esko, T., Evans, DM., Franke, L., Gögele, M., Hartiala, J., Hersch, M., Holm, H., Hottenga, JJ., Kanoni, S., Kleber, ME., Lagou, V., Langenberg, C., Lopez, LM., Lyytikäinen, LP., Melander, O., Murgia, F., Nolte, IM., O'Reilly, PF., Padmanabhan, S., Parsa, A., Pirastu, N., Porcu, E., Portas, L., Prokopenko, I., Ried, JS., Shin, SY., Tang, CS., Teumer, A., Traglia, M., Ulivi, S., Westra, HJ., Yang, J., Zhao, JH., Anni, F., Abdellaoui, A., Attwood, A., Balkau, B., Bandinelli, S., Bastardot, F., Benyamin, B., Boehm, BO., Cookson, WO., Das, D., de Bakker, PI., de Boer, RA., de Geus, EJ., de Moor, MH., Dimitriou, M., Domingues, FS., Döring, A., Engström, G., Eyjolfsson, GI., Ferrucci, L., Fischer, K., Galanello, R., Garner, SF., Genser, B., Gibson, QD., Girotto, G., Gudbjartsson, DF., Harris, SE., Hartikainen, AL., Hastie, CE., Hedblad, B., Illig, T., Jolley, J., Kähönen, M., Kema, IP., Kemp, JP., Liang, L., Lloyd-Jones, H., Loos, RJ., Meacham, S., Medland, SE., Meisinger, C., Memari, Y., Mihailov, E., Miller, K., Moffatt, MF., Nauck, M., Novatchkova, M., Nutile, T., Olafsson, I., Onundarson, PT., Parracciani, D., Penninx, BW., Perseu, L., Piga, A., Pistis, G., Pouta, A., Puc, U., Raitakari, O., Ring, SM., Robino, A., Ruggiero, D., Ruokonen, A., Saint-Pierre, A., Sala, C., Salumets, A., Sambrook, J., Schepers, H., Schmidt, CO., Silljé, HH., Sladek, R., Smit, JH., Starr, JM., Stephens, J., Sulem, P., Tanaka, T., Thorsteinsdottir, U., Tragante, V., van Gilst, WH., van Pelt, LJ., van Veldhuisen, DJ., Völker, U., Whitfield, JB., Willemsen, G., Winkelmann, BR., Wirnsberger, G., Algra, A., Cucca, F., d'Adamo, AP., Danesh, J., Deary, IJ., Dominiczak, AF., Elliott, P., Fortina, P., Froguel, P., Gasparini, P., Greinacher, A., Hazen, SL., Jarvelin, MR., Khaw, KT., Lehtimäki, T., Maerz, W., Martin, NG., Metspalu, A., Mitchell, BD., Montgomery, GW., Moore, C., Navis, G., Pirastu, M., Pramstaller, PP., Ramirez-Solis, R., Schadt, E., Scott, J., Shuldiner, AR., Smith, GD., Smith, JG., Snieder, H., Sorice, R., Spector, TD., Stefansson, K., Stumvoll, M., Tang, WH., Toniolo, D., Tönjes, A., Visscher, PM., Vollenweider, P., Wareham, NJ., Wolffenbuttel, BH., Boomsma, DI., Beckmann, JS., Dedoussis, GV., Deloukas, P., Ferreira, MA., Sanna, S., Uda, M., Hicks, AA., Penninger, JM., Gieger, C., Kooner, JS., Ouwehand, WH., Soranzo, N., Chambers, JC. (2012) Seventy-five genetic loci influencing the human red blood cell. Nature. 492(7429):369-75

Vaziri, A., Emiliani, V. (2012) Reshaping the optical dimension in optogenetics. Curr Opin Neurobiol. 22(1):128-37

Vilagos, B., Hoffmann, M., Souabni, A., Sun, Q., Werner, B., Medvedovic, J., Bilic, I., Minnich, M., Axelsson, E., Jaritz, M., Busslinger, M. (2012) Essential role of EBF1 in the generation and function of distinct mature B cell types. J Exp Med. 209(4):775-92

Vinzenz, M., Nemethova, M., Schur, F., Mueller, J., Narita, A., Urban, E., Winkler, C., Schmeiser, C., Koestler, SA., Rottner, K., Resch, GP., Maeda, Y., Small, JV. (2012) Actin branching in the initiation and maintenance of lamellipodia. J Cell Sci. 125(Pt 11):2775-85

Whelan, G., Kreidl, E., Peters, JM., Eichele, G. (2012) The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions. Nucleus. 3(4):330-4

Whelan, G., Kreidl, E., Wutz, G., Egner, A., Peters, JM., Eichele, G. (2012) Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J. 31(1):71-82

Wray, J., Hartmann, C. (2012) WNTing embryonic stem cells. Trends Cell Biol. 22(3):159-68

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, AR., Simon, J., Zhang, J., Luo, W., Hicks, J., Zender, L., Wang, XW., Powers, S., Wigler, M., Lowe, SW. (2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 109(21):8212-7

Yáñez-Cuna, JO., Dinh, HQ., Kvon, EZ., Shlyueva, D., Stark, A. (2012) Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding. Genome Res. 22(10):2018-30

Zimniak, T., Fitz, V., Zhou, H., Lampert, F., Opravil, S., Mechtler, K., Stolt-Bergner, P., Westermann, S. (2012) Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation. Curr Biol. 22(9):787-93

2011

Agrelo R. (2011) X Inactivation and Progenitor Cancer Cells Cancers. 3(2):2169-2175

Alexander, J., Lim, D., Joughin, BA., Hegemann, B., Hutchins, JR., Ehrenberger, T., Ivins, F., Sessa, F., Hudecz, O., Nigg, EA., Fry, AM., Musacchio, A., Stukenberg, PT., Mechtler, K., Peters, JM., Smerdon, SJ., Yaffe, MB. (2011) Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal. 4(179):ra42

Bakiri, L., Reschke, MO., Gefroh, HA., Idarraga, MH., Polzer, K., Zenz, R., Schett, G., Wagner, EF. (2011) Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis. Oncogene. 30(13):1506-17

Bardet, AF., He, Q., Zeitlinger, J., Stark, A. (2011) A computational pipeline for comparative ChIP-seq analyses. Nat Protoc. 7(1):45-61

Böhmdorfer, G., Schleiffer, A., Brunmeir, R., Ferscha, S., Nizhynska, V., Kozák, J., Angelis, KJ., Kreil, DP., Schweizer, D. (2011) GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis. Plant J. 67(3):420-33

Breitwieser, FP., Müller, A., Dayon, L., Köcher, T., Hainard, A., Pichler, P., Schmidt-Erfurth, U., Superti-Furga, G., Sanchez, JC., Mechtler, K., Bennett, KL., Colinge, J. (2011) General statistical modeling of data from protein relative expression isobaric tags. J Proteome Res. 10(6):2758-66

Buschhorn, BA., Petzold, G., Galova, M., Dube, P., Kraft, C., Herzog, F., Stark, H., Peters, JM. (2011) Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. Nat Struct Mol Biol. 18(1):6-13

Campbell, LJ., Suárez-Castillo, EC., Ortiz-Zuazaga, H., Knapp, D., Tanaka, EM., Crews, CM. (2011) Gene expression profile of the regeneration epithelium during axolotl limb regeneration. Dev Dyn. 240(7):1826-40

Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) HTRA proteases: regulated proteolysis in protein quality control. Nat Rev Mol Cell Biol. 12(3):152-62

Cretney, E., Xin, A., Shi, W., Minnich, M., Masson, F., Miasari, M., Belz, GT., Smyth, GK., Busslinger, M., Nutt, SL., Kallies, A. (2011) The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol. 12(4):304-11

Ebert, A., McManus, S., Tagoh, H., Medvedovic, J., Salvagiotto, G., Novatchkova, M., Tamir, I., Sommer, A., Jaritz, M., Busslinger, M. (2011) The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity. 34(2):175-87

Edwards, A., Treiber, CD., Breuss, M., Pidsley, R., Huang, GJ., Cleak, J., Oliver, PL., Flint, J., Keays, DA. (2011) Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse. Neuroscience. 195:191-200

Elling, U., Taubenschmid, J., Wirnsberger, G., O'Malley, R., Demers, SP., Vanhaelen, Q., Shukalyuk, AI., Schmauss, G., Schramek, D., Schnuetgen, F., von Melchner, H., Ecker, JR., Stanford, WL., Zuber, J., Stark, A., Penninger, JM. (2011) Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. Cell Stem Cell. 9(6):563-74

Elsayad, K., Suplata, M., Heinze, KG. (2011) Using MATLAB to Achieve Nanoscale Optical Sectioning in the Vicinity of Metamaterial Substrates by Simulating Emitter-Substrate Interactions Engineering Education and Research Using MATLAB.

Fellmann, C., Zuber, J., McJunkin, K., Chang, K., Malone, CD., Dickins, RA., Xu, Q., Hengartner, MO., Elledge, SJ., Hannon, GJ., Lowe, SW. (2011) Functional identification of optimized RNAi triggers using a massively parallel sensor assay. Mol Cell. 41(6):733-46

Fischer, H., Szabo, S., Scherz, J., Jaeger, K., Rossiter, H., Buchberger, M., Ghannadan, M., Hermann, M., Theussl, HC., Tobin, DJ., Wagner, EF., Tschachler, E., Eckhart, L. (2011) Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. J Invest Dermatol. 131(6):1208-15

Ganim, Z., Tokmakoff, A., Vaziri, A. (2011) Vibrational excitons in ionophores: experimental probes for quantum coherence-assisted ion transport and selectivity in ion channels New J. Phys.. 13

Gimferrer, I., Hu, T., Simmons, A., Wang, C., Souabni, A., Busslinger, M., Bender, TP., Hernandez-Hoyos, G., Alberola-Ila, J. (2011) Regulation of GATA-3 expression during CD4 lineage differentiation. J Immunol. 186(7):3892-8

Grebien, F., Hantschel, O., Wojcik, J., Kaupe, I., Kovacic, B., Wyrzucki, AM., Gish, GD., Cerny-Reiterer, S., Koide, A., Beug, H., Pawson, T., Valent, P., Koide, S., Superti-Furga, G. (2011) Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell. 147(2):306-19

Grosstessner-Hain, K., Hegemann, B., Novatchkova, M., Rameseder, J., Joughin, BA., Hudecz, O., Roitinger, E., Pichler, P., Kraut, N., Yaffe, MB., Peters, JM., Mechtler, K. (2011) Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome. Mol Cell Proteomics. 10(11):M111.008540

Guo, C., Yoon, HS., Franklin, A., Jain, S., Ebert, A., Cheng, HL., Hansen, E., Despo, O., Bossen, C., Vettermann, C., Bates, JG., Richards, N., Myers, D., Patel, H., Gallagher, M., Schlissel, MS., Murre, C., Busslinger, M., Giallourakis, CC., Alt, FW. (2011) CTCF-binding elements mediate control of V(D)J recombination. Nature. 477(7365):424-30

Häärä, O., Fujimori, S., Schmidt-Ullrich, R., Hartmann, C., Thesleff, I., Mikkola, ML. (2011) Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. Development. 138(13):2681-91

Hadjieconomou, D., Rotkopf, S., Alexandre, C., Bell, DM., Dickson, BJ., Salecker, I. (2011) Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. Nat Methods. 8(3):260-6

Handler, D., Olivieri, D., Novatchkova, M., Gruber, FS., Meixner, K., Mechtler, K., Stark, A., Sachidanandam, R., Brennecke, J. (2011) A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J. 30(19):3977-93

Hasanovic, A., Winkler, R., Resch, GP., Valenta, C. (2011) Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir. Eur J Pharm Biopharm. 79(1):76-81

He, Q., Bardet, AF., Patton, B., Purvis, J., Johnston, J., Paulson, A., Gogol, M., Stark, A., Zeitlinger, J. (2011) High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species. Nat Genet. 43(5):414-20

Hegemann, B., Hutchins, JR., Hudecz, O., Novatchkova, M., Rameseder, J., Sykora, MM., Liu, S., Mazanek, M., Lénárt, P., Hériché, JK., Poser, I., Kraut, N., Hyman, AA., Yaffe, MB., Mechtler, K., Peters, JM. (2011) Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal. 4(198):rs12

Heuck, A., Schleiffer, A., Clausen, T. (2011) Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins. J Mol Biol. 406(5):659-66

Hilgers, V., Perry, MW., Hendrix, D., Stark, A., Levine, M., Haley, B. (2011) Neural-specific elongation of 3' UTRs during Drosophila development. Proc Natl Acad Sci U S A. 108(38):15864-9

Holzmann, J., Fuchs, J., Pichler, P., Peters, JM., Mechtler, K. (2011) Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads. J Proteome Res. 10(2):780-9

Hornung, P., Maier, M., Alushin, GM., Lander, GC., Nogales, E., Westermann, S. (2011) Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. J Mol Biol. 405(2):548-59

Huang, R., Jaritz, M., Guenzl, P., Vlatkovic, I., Sommer, A., Tamir, IM., Marks, H., Klampfl, T., Kralovics, R., Stunnenberg, HG., Barlow, DP., Pauler, FM. (2011) An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One. 6(11):e27288

Jászai, J., Fargeas, CA., Graupner, S., Tanaka, EM., Brand, M., Huttner, WB., Corbeil, D. (2011) Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species. PLoS One. 6(3):e17590

Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2011) Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin. Virology. 412(1):55-67

Kley, J., Schmidt, B., Boyanov, B., Stolt-Bergner, PC., Kirk, R., Ehrmann, M., Knopf, RR., Naveh, L., Adam, Z., Clausen, T. (2011) Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure. Nat Struct Mol Biol. 18(6):728-31

Köcher, T. (2011) Comment on 'Jobs for the boys'. EMBO Rep. 12(6):488

Köcher, T., Pichler, P., Mazanek, M., Swart, R., Mechtler, K. (2011) Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications. Anal Bioanal Chem. 400(8):2339-47

Köcher, T., Pichler, P., Swart, R., Mechtler, K. (2011) Quality control in LC-MS/MS. Proteomics. 11(6):1026-30

Köcher, T., Swart, R., Mechtler, K. (2011) Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides. Anal Chem. 83(7):2699-704

Kramer, JM., Kochinke, K., Oortveld, MA., Marks, H., Kramer, D., de Jong, EK., Asztalos, Z., Westwood, JT., Stunnenberg, HG., Sokolowski, MB., Keleman, K., Zhou, H., van Bokhoven, H., Schenck, A. (2011) Epigenetic regulation of learning and memory by Drosophila EHMT/G9a. PLoS Biol. 9(1):e1000569

Lampert, F., Westermann, S. (2011) A blueprint for kinetochores - new insights into the molecular mechanics of cell division. Nat Rev Mol Cell Biol. 12(7):407-12

Lindblad-Toh, K., Garber, M., Zuk, O., Lin, MF., Parker, BJ., Washietl, S., Kheradpour, P., Ernst, J., Jordan, G., Mauceli, E., Ward, LD., Lowe, CB., Holloway, AK., Clamp, M., Gnerre, S., Alföldi, J., Beal, K., Chang, J., Clawson, H., Cuff, J., Di Palma, F., Fitzgerald, S., Flicek, P., Guttman, M., Hubisz, MJ., Jaffe, DB., Jungreis, I., Kent, WJ., Kostka, D., Lara, M., Martins, AL., Massingham, T., Moltke, I., Raney, BJ., Rasmussen, MD., Robinson, J., Stark, A., Vilella, AJ., Wen, J., Xie, X., Zody, MC., Baldwin, J., Bloom, T., Chin, CW., Heiman, D., Nicol, R., Nusbaum, C., Young, S., Wilkinson, J., Worley, KC., Kovar, CL., Muzny, DM., Gibbs, RA., Cree, A., Dihn, HH., Fowler, G., Jhangiani, S., Joshi, V., Lee, S., Lewis, LR., Nazareth, LV., Okwuonu, G., Santibanez, J., Warren, WC., Mardis, ER., Weinstock, GM., Wilson, RK., Delehaunty, K., Dooling, D., Fronik, C., Fulton, L., Fulton, B., Graves, T., Minx, P., Sodergren, E., Birney, E., Margulies, EH., Herrero, J., Green, ED., Haussler, D., Siepel, A., Goldman, N., Pollard, KS., Pedersen, JS., Lander, ES., Kellis, M. (2011) A high-resolution map of human evolutionary constraint using 29 mammals. Nature. 478(7370):476-82

Loewenstein, Y., Kuras, A., Rumpel, S. (2011) Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo. J Neurosci. 31(26):9481-8

Lyashenko, N., Winter, M., Migliorini, D., Biechele, T., Moon, RT., Hartmann, C. (2011) Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol. 13(7):753-61

Malle, E., Zhou, H., Neuhold, J., Spitzenberger, B., Klepsch, F., Pollak, T., Bergner, O., Ecker, GF., Stolt-Bergner, PC. (2011) Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues. J Biol Chem. 286(26):23121-31

McManus, S., Ebert, A., Salvagiotto, G., Medvedovic, J., Sun, Q., Tamir, I., Jaritz, M., Tagoh, H., Busslinger, M. (2011) The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J. 30(12):2388-404

Mechtcheriakova, D., Sobanov, Y., Holtappels, G., Bajna, E., Svoboda, M., Jaritz, M., Bachert, C., Jensen-Jarolim, E. (2011) Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. PLoS One. 6(10):e25611

Medvedovic, J., Ebert, A., Tagoh, H., Busslinger, M. (2011) Pax5: a master regulator of B cell development and leukemogenesis. Adv Immunol. 111:179-206

Merdanovic, M., Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) Protein quality control in the bacterial periplasm. Annu Rev Microbiol. 65:149-68

Nacu, E., Tanaka, EM. (2011) Limb regeneration: a new development? Annu Rev Cell Dev Biol. 27:409-40

Neumüller, RA., Richter, C., Fischer, A., Novatchkova, M., Neumüller, KG., Knoblich, JA. (2011) Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93

Ng, K., Daigle, N., Bancaud, A., Ohhata, T., Humphreys, P., Walker, R., Ellenberg, J., Wutz, A. (2011) A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells. Mol Biol Cell. 22(14):2634-45

Pappu, KS., Morey, M., Nern, A., Spitzweck, B., Dickson, BJ., Zipursky, SL. (2011) Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development. Proc Natl Acad Sci U S A. 108(18):7571-6

Pichler, P., Köcher, T., Holzmann, J., Möhring, T., Ammerer, G., Mechtler, K. (2011) Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell. Anal Chem. 83(4):1469-74

Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, CL., Lührmann, R., Söll, D., Martinez, J. (2011) HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science. 331(6018):760-4

Qin, H., Suzuki, K., Nakata, M., Chikuma, S., Izumi, N., Huong, le T., Maruya, M., Fagarasan, S., Busslinger, M., Honjo, T., Nagaoka, H. (2011) Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One. 6(12):e29141

Resch, GP., Brandstetter, M., Pickl-Herk, AM., Königsmaier, L., Wonesch, VI., Urban, E. (2011) Immersion freezing of biological specimens: rationale, principles, and instrumentation. Cold Spring Harb Protoc. 2011(7):778-82

Sampaio, JL., Gerl, MJ., Klose, C., Ejsing, CS., Beug, H., Simons, K., Shevchenko, A. (2011) Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A. 108(5):1903-7

Sawa, J., Malet, H., Krojer, T., Canellas, F., Ehrmann, M., Clausen, T. (2011) Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope. J Biol Chem. 286(35):30680-90

Schönbauer, C., Distler, J., Jährling, N., Radolf, M., Dodt, HU., Frasch, M., Schnorrer, F. (2011) Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479(7373):406-9

Schraidt, O., Marlovits, TC. (2011) Three-dimensional model of Salmonella's needle complex at subnanometer resolution. Science. 331(6021):1192-5

Stöger-Pollach, M., Treiber, CD., Resch, GP., Keays, DA., Ennen, I. (2011) EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 42(5):456-60

Takada, Y., Gresh, L., Bozec, A., Ikeda, E., Kamiya, K., Watanabe, M., Kobayashi, K., Asano, K., Toyama, Y., Wagner, EF., Matsuo, K. (2011) Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-1. Oncogene. 30(36):3821-32

Tanaka, EM., Reddien, PW. (2011) The cellular basis for animal regeneration. Dev Cell. 21(1):172-85

Taschler, U., Radner, FP., Heier, C., Schreiber, R., Schweiger, M., Schoiswohl, G., Preiss-Landl, K., Jaeger, D., Reiter, B., Koefeler, HC., Wojciechowski, J., Theussl, C., Penninger, JM., Lass, A., Haemmerle, G., Zechner, R., Zimmermann, R. (2011) Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J Biol Chem. 286(20):17467-77

Taus, T., Köcher, T., Pichler, P., Paschke, C., Schmidt, A., Henrich, C., Mechtler, K. (2011) Universal and confident phosphorylation site localization using phosphoRS. J Proteome Res. 10(12):5354-62

Truebestein, L., Tennstaedt, A., Mönig, T., Krojer, T., Canellas, F., Kaiser, M., Clausen, T., Ehrmann, M. (2011) Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat Struct Mol Biol. 18(3):386-8

von Philipsborn, AC., Liu, T., Yu, JY., Masser, C., Bidaye, SS., Dickson, BJ. (2011) Neuronal control of Drosophila courtship song. Neuron. 69(3):509-22

York, AG., Ghitani, A., Vaziri, A., Davidson, MW., Shroff, H. (2011) Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes. Nat Methods. 8(4):327-33

Zuber, J., Rappaport, AR., Luo, W., Wang, E., Chen, C., Vaseva, AV., Shi, J., Weissmueller, S., Fellmann, C., Fellman, C., Taylor, MJ., Weissenboeck, M., Graeber, TG., Kogan, SC., Vakoc, CR., Lowe, SW. (2011) An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev. 25(15):1628-40

Zuber, J., Shi, J., Wang, E., Rappaport, AR., Herrmann, H., Sison, EA., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., Taylor, MJ., Johns, C., Chicas, A., Mulloy, JC., Kogan, SC., Brown, P., Valent, P., Bradner, JE., Lowe, SW., Vakoc, CR. (2011) RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature. 478(7370):524-8

2010

Agrelo, R., Wutz, A. (2010) ConteXt of change--X inactivation and disease. EMBO Mol Med. 2(1):6-15

Agrelo, R., Wutz, A. (2010) X inactivation and disease. Semin Cell Dev Biol. 21(2):194-200

Alpert, AJ., Petritis, K., Kangas, L., Smith, RD., Mechtler, K., Mitulović, G., Mohammed, S., Heck, AJ. (2010) Peptide orientation affects selectivity in ion-exchange chromatography. Anal Chem. 82(12):5253-9

Antos, CL., Tanaka, EM. (2010) Vertebrates that regenerate as models for guiding stem cels. Adv Exp Med Biol. 695:184-214

Baudrimont, A., Penkner, A., Woglar, A., Machacek, T., Wegrostek, C., Gloggnitzer, J., Fridkin, A., Klein, F., Gruenbaum, Y., Pasierbek, P., Jantsch, V. (2010) Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans. PLoS Genet. 6(11):e1001219

Baumann, CL., Aspalter, IM., Sharif, O., Pichlmair, A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, KL., Colinge, J., Knapp, S., Superti-Furga, G. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med. 207(12):2689-701

Berg, DA., Kirkham, M., Beljajeva, A., Knapp, D., Habermann, B., Ryge, J., Tanaka, EM., Simon, A. (2010) Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain. Development. 137(24):4127-34

Bouchard, M., de Caprona, D., Busslinger, M., Xu, P., Fritzsch, B. (2010) Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol. 10:89

Braglia, P., Heindl, K., Schleiffer, A., Martinez, J., Proudfoot, NJ. (2010) Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I. EMBO Rep. 11(10):758-64

Braun, A., Breuss, M., Salzer, MC., Flint, J., Cowan, NJ., Keays, DA. (2010) Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 86(5):819-22; author reply 822-3

Cachero, S., Ostrovsky, AD., Yu, JY., Dickson, BJ., Jefferis, GS. (2010) Sexual dimorphism in the fly brain. Curr Biol. 20(18):1589-601

Csiszar, A., Vogelsang, E., Beug, H., Leptin, M. (2010) A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol. 30(8):2017-27

Dickson, BJ., Zou, Y. (2010) Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol. 2(8):a002055

El-Kasaby, A., Just, H., Malle, E., Stolt-Bergner, PC., Sitte, HH., Freissmuth, M., Kudlacek, O. (2010) Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem. 285(50):39201-10

Elsayad, K., Heinze, KG. (2010) Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks Physical Review A. 81(5)

Elsayad, K., Heinze, KG. (2010) Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films Proc. SPIE. 7757:77573L

Elsayad, K., Urich, A., Unterrainer, K., Heinze, KG. (2010) Fast near-field imaging of spectrally broad sources using layered metallic structures Proc. SPIE. 7757:77573M

Eskeland, R., Leeb, M., Grimes, GR., Kress, C., Boyle, S., Sproul, D., Gilbert, N., Fan, Y., Skoultchi, AI., Wutz, A., Bickmore, WA. (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 38(3):452-64

Feng, W., Yonezawa, M., Ye, J., Jenuwein, T., Grummt, I. (2010) PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol. 17(4):445-50

Friedbichler, K., Kerenyi, MA., Kovacic, B., Li, G., Hoelbl, A., Yahiaoui, S., Sexl, V., Müllner, EW., Fajmann, S., Cerny-Reiterer, S., Valent, P., Beug, H., Gouilleux, F., Bunting, KD., Moriggl, R. (2010) Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood. 116(9):1548-58

Fuchs, A., Inthal, A., Herrmann, D., Cheng, S., Nakatomi, M., Peters, H., Neubüser, A. (2010) Regulation of Tbx22 during facial and palatal development. Dev Dyn. 239(11):2860-74

Fujimori, S., Novak, H., Weissenböck, M., Jussila, M., Gonçalves, A., Zeller, R., Galloway, J., Thesleff, I., Hartmann, C. (2010) Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 348(1):97-106

Galkin, VE., Schmied, WH., Schraidt, O., Marlovits, TC., Egelman, EH. (2010) The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system. J Mol Biol. 396(5):1392-7

Gin, E., Tanaka, EM., Brusch, L. (2010) A model for cyst lumen expansion and size regulation via fluid secretion. J Theor Biol. 264(3):1077-88

Grausenburger, R., Bilic, I., Boucheron, N., Zupkovitz, G., El-Housseiny, L., Tschismarov, R., Zhang, Y., Rembold, M., Gaisberger, M., Hartl, A., Epstein, MM., Matthias, P., Seiser, C., Ellmeier, W. (2010) Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol. 185(6):3489-97

Haider, S., Wagner, M., Schmid, MC., Sixt, BS., Christian, JG., Häcker, G., Pichler, P., Mechtler, K., Müller, A., Baranyi, C., Toenshoff, ER., Montanaro, J., Horn, M. (2010) Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae. Mol Microbiol. 77(3):687-700

Hasenbein, S., Meltzer, M., Hauske, P., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2010) Conversion of a regulatory into a degradative protease. J Mol Biol. 397(4):957-66

Haubner, BJ., Neely, GG., Voelkl, JG., Damilano, F., Kuba, K., Imai, Y., Komnenovic, V., Mayr, A., Pachinger, O., Hirsch, E., Penninger, JM., Metzler, B. (2010) PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway. PLoS One. 5(2):e9350

Heinz, E., Pichler, P., Heinz, C., Op den Camp, HJ., Toenshoff, ER., Ammerer, G., Mechtler, K., Wagner, M., Horn, M. (2010) Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies. Proteomics. 10(24):4363-76

Herrmann, D., Ferrer-Vaquer, A., Lahsnig, C., Firnberg, N., Leibbrandt, A., Neubüser, A. (2010) Expression and regulation of ANTXR1 in the chick embryo. Dev Dyn. 239(2):680-7

Hnisz, D., Majer, O., Frohner, IE., Komnenovic, V., Kuchler, K. (2010) The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog. 6(5):e1000889

Hoelbl, A., Schuster, C., Kovacic, B., Zhu, B., Wickre, M., Hoelzl, MA., Fajmann, S., Grebien, F., Warsch, W., Stengl, G., Hennighausen, L., Poli, V., Beug, H., Moriggl, R., Sexl, V. (2010) Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med. 2(3):98-110

Huang, J., Dorsey, J., Chuikov, S., Pérez-Burgos, L., Zhang, X., Jenuwein, T., Reinberg, D., Berger, SL. (2010) G9a and Glp methylate lysine 373 in the tumor suppressor p53. J Biol Chem. 285(13):9636-41

Huber, MA., Maier, HJ., Alacakaptan, M., Wiedemann, E., Braunger, J., Boehmelt, G., Madwed, JB., Young, ER., Marshall, DR., Pehamberger, H., Wirth, T., Kraut, N., Beug, H. (2010) BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. Genes Cancer. 1(2):101-14

Hutchins, JR., Toyoda, Y., Hegemann, B., Poser, I., Hériché, JK., Sykora, MM., Augsburg, M., Hudecz, O., Buschhorn, BA., Bulkescher, J., Conrad, C., Comartin, D., Schleiffer, A., Sarov, M., Pozniakovsky, A., Slabicki, MM., Schloissnig, S., Steinmacher, I., Leuschner, M., Ssykor, A., Lawo, S., Pelletier, L., Stark, H., Nasmyth, K., Ellenberg, J., Durbin, R., Buchholz, F., Mechtler, K., Hyman, AA., Peters, JM. (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 328(5978):593-9

Ishizaki, K., Suzuki, K., Mito, T., Tanaka, EM., Sato, S. (2010) Morphologic, functional, and occlusal characterization of mandibular lateral displacement malocclusion. Am J Orthod Dentofacial Orthop. 137(4):454.e1-9; discussion 454-5

Johnson, BA., Kahler, DJ., Baban, B., Chandler, PR., Kang, B., Shimoda, M., Koni, PA., Pihkala, J., Vilagos, B., Busslinger, M., Munn, DH., Mellor, AL. (2010) B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A. 107(23):10644-8

Karginov, FV., Cheloufi, S., Chong, MM., Stark, A., Smith, AD., Hannon, GJ. (2010) Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases. Mol Cell. 38(6):781-8

Katis, VL., Lipp, JJ., Imre, R., Bogdanova, A., Okaz, E., Habermann, B., Mechtler, K., Nasmyth, K., Zachariae, W. (2010) Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Dev Cell. 18(3):397-409

Keays, DA., Cleak, J., Huang, GJ., Edwards, A., Braun, A., Treiber, CD., Pidsley, R., Flint, J. (2010) The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus. Dev Neurosci. 32(4):268-77

Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2010) Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway. J Virol. 84(8):3984-92

Kim, YJ., Bartalska, K., Audsley, N., Yamanaka, N., Yapici, N., Lee, JY., Kim, YC., Markovic, M., Isaac, E., Tanaka, Y., Dickson, BJ. (2010) MIPs are ancestral ligands for the sex peptide receptor. Proc Natl Acad Sci U S A. 107(14):6520-5

Krojer, T., Sawa, J., Huber, R., Clausen, T. (2010) HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol. 17(7):844-52

Kuçi, S., Kuçi, Z., Kreyenberg, H., Deak, E., Pütsch, K., Huenecke, S., Amara, C., Koller, S., Rettinger, E., Grez, M., Koehl, U., Latifi-Pupovci, H., Henschler, R., Tonn, T., von Laer, D., Klingebiel, T., Bader, P. (2010) CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties. Haematologica. 95(4):651-9

Lampert, F., Hornung, P., Westermann, S. (2010) The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex. J Cell Biol. 189(4):641-9

Leeb, M., Pasini, D., Novatchkova, M., Jaritz, M., Helin, K., Wutz, A. (2010) Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev. 24(3):265-76

Leeb, M., Wutz, A. (2010) Mechanistic concepts in X inactivation underlying dosage compensation in mammals. Heredity (Edinb). 105(1):64-70

Leitner, A., Sturm, M., Hudecz, O., Mazanek, M., Smått, JH., Lindén, M., Lindner, W., Mechtler, K. (2010) Probing the phosphoproteome of HeLa cells using nanocast metal oxide microspheres for phosphopeptide enrichment. Anal Chem. 82(7):2726-33

Lukaszewicz, A., Howard-Till, RA., Novatchkova, M., Mochizuki, K., Loidl, J. (2010) MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena. Chromosoma. 119(5):505-18

Lyashenko, N., Weissenböck, M., Sharir, A., Erben, RG., Minami, Y., Hartmann, C. (2010) Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn. 239(8):2266-77

Mach-Aigner, AR., Grosstessner-Hain, K., Poças-Fonseca, MJ., Mechtler, K., Mach, RL. (2010) From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach. BMC Genomics. 11:644

Maier HJ., Wirth T., Beug H. (2010) Epithelial-Mesenchymal Transition in Pancreatic Carcinoma Cancers . 2(4):2058-2083

Maier, HJ., Schmidt-Strassburger, U., Huber, MA., Wiedemann, EM., Beug, H., Wirth, T. (2010) NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett. 295(2):214-28

Majewski, IJ., Ritchie, ME., Phipson, B., Corbin, J., Pakusch, M., Ebert, A., Busslinger, M., Koseki, H., Hu, Y., Smyth, GK., Alexander, WS., Hilton, DJ., Blewitt, ME. (2010) Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood. 116(5):731-9

Malin, S., McManus, S., Busslinger, M. (2010) STAT5 in B cell development and leukemia. Curr Opin Immunol. 22(2):168-76

Malin, S., McManus, S., Cobaleda, C., Novatchkova, M., Delogu, A., Bouillet, P., Strasser, A., Busslinger, M. (2010) Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development. Nat Immunol. 11(2):171-9

Marlovits, TC., Stebbins, CE. (2010) Type III secretion systems shape up as they ship out. Curr Opin Microbiol. 13(1):47-52

Marth, K., Novatchkova, M., Focke-Tejkl, M., Jenisch, S., Jäger, S., Kabelitz, D., Valenta, R. (2010) Tracing antigen signatures in the human IgE repertoire. Mol Immunol. 47(14):2323-9

Maschler, S., Gebeshuber, CA., Wiedemann, EM., Alacakaptan, M., Schreiber, M., Custic, I., Beug, H. (2010) Annexin A1 attenuates EMT and metastatic potential in breast cancer. EMBO Mol Med. 2(10):401-14

Mazanek, M., Roitinger, E., Hudecz, O., Hutchins, JR., Hegemann, B., Mitulović, G., Taus, T., Stingl, C., Peters, JM., Mechtler, K. (2010) A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes. J Chromatogr B Analyt Technol Biomed Life Sci. 878(5-6):515-24

Molatore, S., Kiermaier, E., Jung, CB., Lee, M., Pulz, E., Höfler, H., Atkinson, MJ., Pellegata, NS. (2010) Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors. Mol Cancer. 9:116

Morandell, S., Grosstessner-Hain, K., Roitinger, E., Hudecz, O., Lindhorst, T., Teis, D., Wrulich, OA., Mazanek, M., Taus, T., Ueberall, F., Mechtler, K., Huber, LA. (2010) QIKS--Quantitative identification of kinase substrates. Proteomics. 10(10):2015-25

Mujezinovic, N., Schneider, G., Wildpaner, M., Mechtler, K., Eisenhaber, F. (2010) Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction. BMC Genomics. 11 Suppl 1:S13

Murchison, EP., Tovar, C., Hsu, A., Bender, HS., Kheradpour, P., Rebbeck, CA., Obendorf, D., Conlan, C., Bahlo, M., Blizzard, CA., Pyecroft, S., Kreiss, A., Kellis, M., Stark, A., Harkins, TT., Marshall Graves, JA., Woods, GM., Hannon, GJ., Papenfuss, AT. (2010) The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science. 327(5961):84-7

Neely, GG., Hess, A., Costigan, M., Keene, AC., Goulas, S., Langeslag, M., Griffin, RS., Belfer, I., Dai, F., Smith, SB., Diatchenko, L., Gupta, V., Xia, CP., Amann, S., Kreitz, S., Heindl-Erdmann, C., Wolz, S., Ly, CV., Arora, S., Sarangi, R., Dan, D., Novatchkova, M., Rosenzweig, M., Gibson, DG., Truong, D., Schramek, D., Zoranovic, T., Cronin, SJ., Angjeli, B., Brune, K., Dietzl, G., Maixner, W., Meixner, A., Thomas, W., Pospisilik, JA., Alenius, M., Kress, M., Subramaniam, S., Garrity, PA., Bellen, HJ., Woolf, CJ., Penninger, JM. (2010) A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Cell. 143(4):628-38

Neely, GG., Kuba, K., Cammarato, A., Isobe, K., Amann, S., Zhang, L., Murata, M., Elmén, L., Gupta, V., Arora, S., Sarangi, R., Dan, D., Fujisawa, S., Usami, T., Xia, CP., Keene, AC., Alayari, NN., Yamakawa, H., Elling, U., Berger, C., Novatchkova, M., Koglgruber, R., Fukuda, K., Nishina, H., Isobe, M., Pospisilik, JA., Imai, Y., Pfeufer, A., Hicks, AA., Pramstaller, PP., Subramaniam, S., Kimura, A., Ocorr, K., Bodmer, R., Penninger, JM. (2010) A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell. 141(1):142-53

Neumann, B., Walter, T., Hériché, JK., Bulkescher, J., Erfle, H., Conrad, C., Rogers, P., Poser, I., Held, M., Liebel, U., Cetin, C., Sieckmann, F., Pau, G., Kabbe, R., Wünsche, A., Satagopam, V., Schmitz, MH., Chapuis, C., Gerlich, DW., Schneider, R., Eils, R., Huber, W., Peters, JM., Hyman, AA., Durbin, R., Pepperkok, R., Ellenberg, J. (2010) Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature. 464(7289):721-7

Neumüller, KG., Elsayad, K., Reisecker, JM., Waxham, MN., Heinze, KG. (2010) Photounbinding of calmodulin from a family of CaM binding peptides. PLoS One. 5(11):e14050

Nishiyama, T., Ladurner, R., Schmitz, J., Kreidl, E., Schleiffer, A., Bhaskara, V., Bando, M., Shirahige, K., Hyman, AA., Mechtler, K., Peters, JM. (2010) Sororin mediates sister chromatid cohesion by antagonizing Wapl. Cell. 143(5):737-49

Olivieri, D., Sykora, MM., Sachidanandam, R., Mechtler, K., Brennecke, J. (2010) An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila. EMBO J. 29(19):3301-17

Owald, D., Fouquet, W., Schmidt, M., Wichmann, C., Mertel, S., Depner, H., Christiansen, F., Zube, C., Quentin, C., Körner, J., Urlaub, H., Mechtler, K., Sigrist, SJ. (2010) A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. J Cell Biol. 188(4):565-79

Pasini, D., Malatesta, M., Jung, HR., Walfridsson, J., Willer, A., Olsson, L., Skotte, J., Wutz, A., Porse, B., Jensen, ON., Helin, K. (2010) Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res. 38(15):4958-69

Pichler, P., Köcher, T., Holzmann, J., Mazanek, M., Taus, T., Ammerer, G., Mechtler, K. (2010) Peptide labeling with isobaric tags yields higher identification rates using iTRAQ 4-plex compared to TMT 6-plex and iTRAQ 8-plex on LTQ Orbitrap. Anal Chem. 82(15):6549-58

Pospisilik, JA., Schramek, D., Schnidar, H., Cronin, SJ., Nehme, NT., Zhang, X., Knauf, C., Cani, PD., Aumayr, K., Todoric, J., Bayer, M., Haschemi, A., Puviindran, V., Tar, K., Orthofer, M., Neely, GG., Dietzl, G., Manoukian, A., Funovics, M., Prager, G., Wagner, O., Ferrandon, D., Aberger, F., Hui, CC., Esterbauer, H., Penninger, JM. (2010) Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate. Cell. 140(1):148-60

Pullirsch, D., Härtel, R., Kishimoto, H., Leeb, M., Steiner, G., Wutz, A. (2010) The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation. Development. 137(6):935-43

Radner, FP., Streith, IE., Schoiswohl, G., Schweiger, M., Kumari, M., Eichmann, TO., Rechberger, G., Koefeler, HC., Eder, S., Schauer, S., Theussl, HC., Preiss-Landl, K., Lass, A., Zimmermann, R., Hoefler, G., Zechner, R., Haemmerle, G. (2010) Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). J Biol Chem. 285(10):7300-11

Reimann, M., Lee, S., Loddenkemper, C., Dörr, JR., Tabor, V., Aichele, P., Stein, H., Dörken, B., Jenuwein, T., Schmitt, CA. (2010) Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence. Cancer Cell. 17(3):262-72

Resch, GP., Urban, E., Jacob, S. (2010) The actin cytoskeleton in whole mount preparations and sections. Methods Cell Biol. 96:529-64

Reschke, M., Ferby, I., Stepniak, E., Seitzer, N., Horst, D., Wagner, EF., Ullrich, A. (2010) Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma. Hepatology. 51(4):1383-90

Ribeiro, C., Dickson, BJ. (2010) Sex peptide receptor and neuronal TOR/S6K signaling modulate nutrient balancing in Drosophila. Curr Biol. 20(11):1000-5

Rovina, P., Jaritz, M., Bornancin, F. (2010) Transcriptional repression of ceramide kinase in LPS-challenged macrophages. Biochem Biophys Res Commun. 401(1):164-7

Rumpf, C., Cipak, L., Dudas, A., Benko, Z., Pozgajova, M., Riedel, CG., Ammerer, G., Mechtler, K., Gregan, J. (2010) Casein kinase 1 is required for efficient removal of Rec8 during meiosis I. Cell Cycle. 9(13):2657-62

Rumpf, C., Cipak, L., Novatchkova, M., Li, Z., Polakova, S., Dudas, A., Kovacikova, I., Miadokova, E., Ammerer, G., Gregan, J. (2010) High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I. Cell Cycle. 9(9):1802-8

Rumpf, C., Cipak, L., Schleiffer, A., Pidoux, A., Mechtler, K., Tolić-Nørrelykke, IM., Gregan, J. (2010) Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4. Cell Cycle. 9(19):3997-4004

Sakaguchi, S., Hombauer, M., Bilic, I., Naoe, Y., Schebesta, A., Taniuchi, I., Ellmeier, W. (2010) The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol. 11(5):442-8

Sawa, J., Heuck, A., Ehrmann, M., Clausen, T. (2010) Molecular transformers in the cell: lessons learned from the DegP protease-chaperone. Curr Opin Struct Biol. 20(2):253-8

Schenk, C., Bringmann, H., Hyman, AA., Cowan, CR. (2010) Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos. Development. 137(10):1743-53

Schmitz, MH., Held, M., Janssens, V., Hutchins, JR., Hudecz, O., Ivanova, E., Goris, J., Trinkle-Mulcahy, L., Lamond, AI., Poser, I., Hyman, AA., Mechtler, K., Peters, JM., Gerlich, DW. (2010) Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat Cell Biol. 12(9):886-93

Schnorrer, F., Schönbauer, C., Langer, CC., Dietzl, G., Novatchkova, M., Schernhuber, K., Fellner, M., Azaryan, A., Radolf, M., Stark, A., Keleman, K., Dickson, BJ. (2010) Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Nature. 464(7286):287-91

Schraidt, O., Lefebre, MD., Brunner, MJ., Schmied, WH., Schmidt, A., Radics, J., Mechtler, K., Galán, JE., Marlovits, TC. (2010) Topology and organization of the Salmonella typhimurium type III secretion needle complex components. PLoS Pathog. 6(4):e1000824

Siekhaus, D., Haesemeyer, M., Moffitt, O., Lehmann, R. (2010) RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila. Nat Cell Biol. 12(6):605-10

Spitzweck, B., Brankatschk, M., Dickson, BJ. (2010) Distinct protein domains and expression patterns confer divergent axon guidance functions for Drosophila Robo receptors. Cell. 140(3):409-20

Stasyk, T., Holzmann, J., Stumberger, S., Ebner, HL., Hess, MW., Bonn, GK., Mechtler, K., Huber, LA. (2010) Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts. Proteomics. 10(22):4117-27

Tian, G., Jaglin, XH., Keays, DA., Francis, F., Chelly, J., Cowan, NJ. (2010) Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway. Hum Mol Genet. 19(18):3599-613

Urban, E., Jacob, S., Nemethova, M., Resch, GP., Small, JV. (2010) Electron tomography reveals unbranched networks of actin filaments in lamellipodia. Nat Cell Biol. 12(5):429-35

Vikstrom, I., Carotta, S., Lüthje, K., Peperzak, V., Jost, PJ., Glaser, S., Busslinger, M., Bouillet, P., Strasser, A., Nutt, SL., Tarlinton, DM. (2010) Mcl-1 is essential for germinal center formation and B cell memory. Science. 330(6007):1095-9

Wagner, S., Königsmaier, L., Lara-Tejero, M., Lefebre, M., Marlovits, TC., Galán, JE. (2010) Organization and coordinated assembly of the type III secretion export apparatus. Proc Natl Acad Sci U S A. 107(41):17745-50

Wang, Y., Souabni, A., Flavell, RA., Wan, YY. (2010) An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo. J Immunol. 185(10):5983-92

Wincent, J., Bruno, DL., van Bon, BW., Bremer, A., Stewart, H., Bongers, EM., Ockeloen, CW., Willemsen, MH., Keays, DD., Baird, G., Newbury, DF., Kleefstra, T., Marcelis, C., Kini, U., Stark, Z., Savarirayan, R., Sheffield, LJ., Zuffardi, O., Slater, HR., de Vries, BB., Knight, SJ., Anderlid, BM., Schoumans, J. (2010) Sixteen New Cases Contributing to the Characterization of Patients with Distal 22q11.2 Microduplications. Mol Syndromol. 1(5):246-254

Yu, JY., Kanai, MI., Demir, E., Jefferis, GS., Dickson, BJ. (2010) Cellular organization of the neural circuit that drives Drosophila courtship behavior. Curr Biol. 20(18):1602-14

Zeitlinger, J., Stark, A. (2010) Developmental gene regulation in the era of genomics. Dev Biol. 339(2):230-9

Zheng, K., Xiol, J., Reuter, M., Eckardt, S., Leu, NA., McLaughlin, KJ., Stark, A., Sachidanandam, R., Pillai, RS., Wang, PJ. (2010) Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway. Proc Natl Acad Sci U S A. 107(26):11841-6

Zulehner, G., Mikula, M., Schneller, D., van Zijl, F., Huber, H., Sieghart, W., Grasl-Kraupp, B., Waldhör, T., Peck-Radosavljevic, M., Beug, H., Mikulits, W. (2010) Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathol. 176(1):472-81

2009

Agrelo, R., Souabni, A., Novatchkova, M., Haslinger, C., Leeb, M., Komnenovic, V., Kishimoto, H., Gresh, L., Kohwi-Shigematsu, T., Kenner, L., Wutz, A. (2009) SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells. Dev Cell. 16(4):507-16

Agrelo, R., Wutz, A. (2009) Cancer progenitors and epigenetic contexts: an Xisting connection. Epigenetics. 4(8):568-70

Baumgartner, C., Cerny-Reiterer, S., Sonneck, K., Mayerhofer, M., Gleixner, KV., Fritz, R., Kerenyi, M., Boudot, C., Gouilleux, F., Kornfeld, JW., Sillaber, C., Moriggl, R., Valent, P. (2009) Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V. Am J Pathol. 175(6):2416-29

Beug, H. (2009) Breast cancer stem cells: eradication by differentiation therapy? Cell. 138(4):623-5

Brehme, M., Hantschel, O., Colinge, J., Kaupe, I., Planyavsky, M., Köcher, T., Mechtler, K., Bennett, KL., Superti-Furga, G. (2009) Charting the molecular network of the drug target Bcr-Abl. Proc Natl Acad Sci U S A. 106(18):7414-9

Breithaupt, C., Kurzbauer, R., Schaller, F., Stintzi, A., Schaller, A., Huber, R., Macheroux, P., Clausen, T. (2009) Structural basis of substrate specificity of plant 12-oxophytodienoate reductases. J Mol Biol. 392(5):1266-77

Bruckner, S., Soltészová, V., Gröller, ME., Hladůvka, J., Bühler, K., Yu, JY., Dickson, BJ. (2009) BrainGazer--visual queries for neurobiology research. IEEE Trans Vis Comput Graph. 15(6):1497-504

Brunner, MJ., Resch, GP. (2009) Automated monitoring to reduce electron microscope downtime. Ultramicroscopy. 109(11):1389-92

Cerqueira, FR., Morandell, S., Ascher, S., Mechtler, K., Huber, LA., Pfeifer, B., Graber, A., Tilg, B., Baumgartner, C. (2009) Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing J Proteomics Bioinform. 2:150-164

Chen, D., Berger, J., Fellner, M., Suzuki, T. (2009) FLYSNPdb: a high-density SNP database of Drosophila melanogaster. Nucleic Acids Res. 37(Database issue):D567-70

Cipak, L., Spirek, M., Novatchkova, M., Chen, Z., Rumpf, C., Lugmayr, W., Mechtler, K., Ammerer, G., Csaszar, E., Gregan, J. (2009) An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes. Proteomics. 9(20):4825-8

d'Erfurth, I., Jolivet, S., Froger, N., Catrice, O., Novatchkova, M., Mercier, R. (2009) Turning meiosis into mitosis. PLoS Biol. 7(6):e1000124

Decker, T., Pasca di Magliano, M., McManus, S., Sun, Q., Bonifer, C., Tagoh, H., Busslinger, M. (2009) Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis. Immunity. 30(4):508-20

Do, JT., Han, DW., Gentile, L., Sobek-Klocke, I., Wutz, A., Schöler, HR. (2009) Reprogramming of Xist against the pluripotent state in fusion hybrids. J Cell Sci. 122(Pt 22):4122-9

Ecker, A., Simma, O., Hoelbl, A., Kenner, L., Beug, H., Moriggl, R., Sexl, V. (2009) The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor. Front Biosci (Landmark Ed). 14:2944-58

Eisenberg, T., Knauer, H., Schauer, A., Büttner, S., Ruckenstuhl, C., Carmona-Gutierrez, D., Ring, J., Schroeder, S., Magnes, C., Antonacci, L., Fussi, H., Deszcz, L., Hartl, R., Schraml, E., Criollo, A., Megalou, E., Weiskopf, D., Laun, P., Heeren, G., Breitenbach, M., Grubeck-Loebenstein, B., Herker, E., Fahrenkrog, B., Fröhlich, KU., Sinner, F., Tavernarakis, N., Minois, N., Kroemer, G., Madeo, F. (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol. 11(11):1305-14

Elsayad, K., Heinze, KG. (2009) Defining a superlens operating regime for imaging fluorescent molecules. PLoS One. 4(12):e7963

Fritz, J., Strehblow, A., Taschner, A., Schopoff, S., Pasierbek, P., Jantsch, MF. (2009) RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1. Mol Cell Biol. 29(6):1487-97

Fuhrmann, J., Schmidt, A., Spiess, S., Lehner, A., Turgay, K., Mechtler, K., Charpentier, E., Clausen, T. (2009) McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science. 324(5932):1323-7

Guinea-Viniegra, J., Zenz, R., Scheuch, H., Hnisz, D., Holcmann, M., Bakiri, L., Schonthaler, HB., Sibilia, M., Wagner, EF. (2009) TNFalpha shedding and epidermal inflammation are controlled by Jun proteins. Genes Dev. 23(22):2663-74

Hanada, R., Leibbrandt, A., Hanada, T., Kitaoka, S., Furuyashiki, T., Fujihara, H., Trichereau, J., Paolino, M., Qadri, F., Plehm, R., Klaere, S., Komnenovic, V., Mimata, H., Yoshimatsu, H., Takahashi, N., von Haeseler, A., Bader, M., Kilic, SS., Ueta, Y., Pifl, C., Narumiya, S., Penninger, JM. (2009) Central control of fever and female body temperature by RANKL/RANK. Nature. 462(7272):505-9

Hartmann, C. (2009) Transcriptional networks controlling skeletal development. Curr Opin Genet Dev. 19(5):437-43

Häsemeyer, M., Yapici, N., Heberlein, U., Dickson, BJ. (2009) Sensory neurons in the Drosophila genital tract regulate female reproductive behavior. Neuron. 61(4):511-8

Hauske, P., Mamant, N., Hasenbein, S., Nickel, S., Ottmann, C., Clausen, T., Ehrmann, M., Kaiser, M. (2009) Peptidic small molecule activators of the stress sensor DegS. Mol Biosyst. 5(9):980-5

Hauske, P., Meltzer, M., Ottmann, C., Krojer, T., Clausen, T., Ehrmann, M., Kaiser, M. (2009) Selectivity profiling of DegP substrates and inhibitors. Bioorg Med Chem. 17(7):2920-4

Heinze, KG., Costantino, S., De Koninck, P., Wiseman, PW. (2009) Beyond photobleaching, laser illumination unbinds fluorescent proteins. J Phys Chem B. 113(15):5225-33

Herzog, F., Primorac, I., Dube, P., Lenart, P., Sander, B., Mechtler, K., Stark, H., Peters, JM. (2009) Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. Science. 323(5920):1477-81

Hewitt, SL., Yin, B., Ji, Y., Chaumeil, J., Marszalek, K., Tenthorey, J., Salvagiotto, G., Steinel, N., Ramsey, LB., Ghysdael, J., Farrar, MA., Sleckman, BP., Schatz, DG., Busslinger, M., Bassing, CH., Skok, JA. (2009) RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci. Nat Immunol. 10(6):655-64

Holzmann, J., Pichler, P., Madalinski, M., Kurzbauer, R., Mechtler, K. (2009) Stoichiometry determination of the MP1-p14 complex using a novel and cost-efficient method to produce an equimolar mixture of standard peptides. Anal Chem. 81(24):10254-61

Hutchins, JR., Moore, WJ., Clarke, PR. (2009) Dynamic localisation of Ran GTPase during the cell cycle. BMC Cell Biol. 10:66

Jaglin, XH., Poirier, K., Saillour, Y., Buhler, E., Tian, G., Bahi-Buisson, N., Fallet-Bianco, C., Phan-Dinh-Tuy, F., Kong, XP., Bomont, P., Castelnau-Ptakhine, L., Odent, S., Loget, P., Kossorotoff, M., Snoeck, I., Plessis, G., Parent, P., Beldjord, C., Cardoso, C., Represa, A., Flint, J., Keays, DA., Cowan, NJ., Chelly, J. (2009) Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nat Genet. 41(6):746-52

Khattak, S., Richter, T., Tanaka, EM. (2009) Generation of transgenic axolotls (Ambystoma mexicanum). Cold Spring Harb Protoc. 2009(8):pdb.prot5264

Khattak, S., Tanaka, EM. (2009) Axolotl (Ambystoma mexicanum) in vitro fertilization. Cold Spring Harb Protoc. 2009(8):pdb.prot5263

Kiermaier, E., Woehrer, S., Peng, Y., Mechtler, K., Westermann, S. (2009) A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast. Nat Cell Biol. 11(9):1109-15

Köcher, T., Pichler, P., Schutzbier, M., Stingl, C., Kaul, A., Teucher, N., Hasenfuss, G., Penninger, JM., Mechtler, K. (2009) High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all. J Proteome Res. 8(10):4743-52

Kragl, M., Tanaka, EM. (2009) Axolotl (Ambystoma mexicanum) limb and tail amputation. Cold Spring Harb Protoc. 2009(8):pdb.prot5267

Kragl, M., Tanaka, EM. (2009) Grafting axolotl (Ambystoma mexicanum) limb skin and cartilage from GFP+ donors to normal hosts. Cold Spring Harb Protoc. 2009(8):pdb.prot5266

Kudo, NR., Anger, M., Peters, AH., Stemmann, O., Theussl, HC., Helmhart, W., Kudo, H., Heyting, C., Nasmyth, K. (2009) Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. J Cell Sci. 122(Pt 15):2686-98

Lahsnig, C., Mikula, M., Petz, M., Zulehner, G., Schneller, D., van Zijl, F., Huber, H., Csiszar, A., Beug, H., Mikulits, W. (2009) ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. Oncogene. 28(5):638-50

Lawo, S., Bashkurov, M., Mullin, M., Ferreria, MG., Kittler, R., Habermann, B., Tagliaferro, A., Poser, I., Hutchins, JR., Hegemann, B., Pinchev, D., Buchholz, F., Peters, JM., Hyman, AA., Gingras, AC., Pelletier, L. (2009) HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity. Curr Biol. 19(10):816-26

Leeb, M., Steffen, PA., Wutz, A. (2009) X chromosome inactivation sparked by non-coding RNAs. RNA Biol. 6(2):94-9

Leitner, A., Sturm, M., Smått, JH., Järn, M., Lindén, M., Mechtler, K., Lindner, W. (2009) Optimizing the performance of tin dioxide microspheres for phosphopeptide enrichment. Anal Chim Acta. 638(1):51-7

McGuinness, BE., Anger, M., Kouznetsova, A., Gil-Bernabé, AM., Helmhart, W., Kudo, NR., Wuensche, A., Taylor, S., Hoog, C., Novak, B., Nasmyth, K. (2009) Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint. Curr Biol. 19(5):369-80

Meireles-Filho, AC., Stark, A. (2009) Comparative genomics of gene regulation-conservation and divergence of cis-regulatory information. Curr Opin Genet Dev. 19(6):565-70

Meltzer, M., Hasenbein, S., Mamant, N., Merdanovic, M., Poepsel, S., Hauske, P., Kaiser, M., Huber, R., Krojer, T., Clausen, T., Ehrmann, M. (2009) Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli. Res Microbiol. 160(9):660-6

Mietton, F., Sengupta, AK., Molla, A., Picchi, G., Barral, S., Heliot, L., Grange, T., Wutz, A., Dimitrov, S. (2009) Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome. Mol Cell Biol. 29(1):150-6

Mitulović, G., Stingl, C., Steinmacher, I., Hudecz, O., Hutchins, JR., Peters, JM., Mechtler, K. (2009) Preventing carryover of peptides and proteins in nano LC-MS separations. Anal Chem. 81(14):5955-60

Müller, KP., Erdel, F., Caudron-Herger, M., Marth, C., Fodor, BD., Richter, M., Scaranaro, M., Beaudouin, J., Wachsmuth, M., Rippe, K. (2009) Multiscale analysis of dynamics and interactions of heterochromatin protein 1 by fluorescence fluctuation microscopy. Biophys J. 97(11):2876-85

Müller, MQ., de Koning, LJ., Schmidt, A., Ihling, C., Syha, Y., Rau, O., Mechtler, K., Schubert-Zsilavecz, M., Sinz, A. (2009) An innovative method to study target protein-drug interactions by mass spectrometry. J Med Chem. 52(9):2875-9

Mummery-Widmer, JL., Yamazaki, M., Stoeger, T., Novatchkova, M., Bhalerao, S., Chen, D., Dietzl, G., Dickson, BJ., Knoblich, JA. (2009) Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi. Nature. 458(7241):987-92

Nacu, E., Knapp, D., Tanaka, EM., Epperlein, HH. (2009) Axolotl (Ambystoma mexicanum) embryonic transplantation methods. Cold Spring Harb Protoc. 2009(8):pdb.prot5265

Nativio, R., Wendt, KS., Ito, Y., Huddleston, JE., Uribe-Lewis, S., Woodfine, K., Krueger, C., Reik, W., Peters, JM., Murrell, A. (2009) Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet. 5(11):e1000739

Ooi, HS., Kwo, CY., Wildpaner, M., Sirota, FL., Eisenhaber, B., Maurer-Stroh, S., Wong, WC., Schleiffer, A., Eisenhaber, F., Schneider, G. (2009) ANNIE: integrated de novo protein sequence annotation. Nucleic Acids Res. 37(Web Server issue):W435-40

Palfreyman, MT. (2009) With Happyhour, everyone's under the table. Cell. 137(5):802-4

Pauler, FM., Sloane, MA., Huang, R., Regha, K., Koerner, MV., Tamir, I., Sommer, A., Aszodi, A., Jenuwein, T., Barlow, DP. (2009) H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome. Genome Res. 19(2):221-33

Penkner, AM., Fridkin, A., Gloggnitzer, J., Baudrimont, A., Machacek, T., Woglar, A., Csaszar, E., Pasierbek, P., Ammerer, G., Gruenbaum, Y., Jantsch, V. (2009) Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1. Cell. 139(5):920-33

Peters, JM., Bhaskara, V. (2009) Cohesin acetylation: from antiestablishment to establishment. Mol Cell. 34(1):1-2

Rowland, BD., Roig, MB., Nishino, T., Kurze, A., Uluocak, P., Mishra, A., Beckouët, F., Underwood, P., Metson, J., Imre, R., Mechtler, K., Katis, VL., Nasmyth, K. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell. 33(6):763-74

Sasaguri, K., Ishizaki-Takeuchi, R., Kuramae, S., Tanaka, EM., Sakurai, T., Sato, S. (2009) The temporomandibular joint in a rheumatoid arthritis patient after orthodontic treatment. Angle Orthod. 79(4):804-11

Schmidt, U., Abramova, A., Boucheron, N., Eckelhart, E., Schebesta, A., Bilic, I., Kneidinger, M., Unger, B., Hammer, M., Sibilia, M., Valent, P., Ellmeier, W. (2009) The protein tyrosine kinase Tec regulates mast cell function. Eur J Immunol. 39(11):3228-38

Schoft, VK., Chumak, N., Mosiolek, M., Slusarz, L., Komnenovic, V., Brownfield, L., Twell, D., Kakutani, T., Tamaru, H. (2009) Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin. EMBO Rep. 10(9):1015-21

Schonthaler, HB., Huggenberger, R., Wculek, SK., Detmar, M., Wagner, EF. (2009) Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis. Proc Natl Acad Sci U S A. 106(50):21264-9

Shoji, M., Tanaka, T., Hosokawa, M., Reuter, M., Stark, A., Kato, Y., Kondoh, G., Okawa, K., Chujo, T., Suzuki, T., Hata, K., Martin, SL., Noce, T., Kuramochi-Miyagawa, S., Nakano, T., Sasaki, H., Pillai, RS., Nakatsuji, N., Chuma, S. (2009) The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 17(6):775-87

Stark, A. (2009) Learning the transcriptional regulatory code. Mol Syst Biol. 5:329

Stockinger, S., Kastner, R., Kernbauer, E., Pilz, A., Westermayer, S., Reutterer, B., Soulat, D., Stengl, G., Vogl, C., Frenz, T., Waibler, Z., Taniguchi, T., Rülicke, T., Kalinke, U., Müller, M., Decker, T. (2009) Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes. PLoS Pathog. 5(3):e1000355

Surmann-Schmitt, C., Widmann, N., Dietz, U., Saeger, B., Eitzinger, N., Nakamura, Y., Rattel, M., Latham, R., Hartmann, C., von der Mark, H., Schett, G., von der Mark, K., Stock, M. (2009) Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis. J Cell Sci. 122(Pt 20):3627-37

Tanaka, EM., Ferretti, P. (2009) Considering the evolution of regeneration in the central nervous system. Nat Rev Neurosci. 10(10):713-23

Trojer, P., Zhang, J., Yonezawa, M., Schmidt, A., Zheng, H., Jenuwein, T., Reinberg, D. (2009) Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. J Biol Chem. 284(13):8395-405

van Zijl, F., Mair, M., Csiszar, A., Schneller, D., Zulehner, G., Huber, H., Eferl, R., Beug, H., Dolznig, H., Mikulits, W. (2009) Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene. 28(45):4022-33

Voss, SR., Epperlein, HH., Tanaka, EM. (2009) Ambystoma mexicanum, the axolotl: a versatile amphibian model for regeneration, development, and evolution studies. Cold Spring Harb Protoc. 2009(8):pdb.emo128

Watrin, E., Peters, JM. (2009) The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells. EMBO J. 28(17):2625-35

Wendt, KS., Peters, JM. (2009) How cohesin and CTCF cooperate in regulating gene expression. Chromosome Res. 17(2):201-14

Wirnsberger, G., Mair, F., Klein, L. (2009) Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control. Proc Natl Acad Sci U S A. 106(25):10278-83

Wutz, A. (2009) Oct4 to count 2. Cell Res. 19(8):917-9

Zimniak, T., Stengl, K., Mechtler, K., Westermann, S. (2009) Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p. J Cell Biol. 186(3):379-91

2008

(2008) Moving AHEAD with an international human epigenome project. Nature. 454(7205):711-5

Bachir, AI., Kolin, DL., Heinze, KG., Hebert, B., Wiseman, PW. (2008) A guide to accurate measurement of diffusion using fluorescence correlation techniques with blinking quantum dot nanoparticle labels. J Chem Phys. 128(22):225105

Barkus, RV., Klyachko, O., Horiuchi, D., Dickson, BJ., Saxton, WM. (2008) Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides. Mol Biol Cell. 19(1):274-83

Berger, J., Senti, KA., Senti, G., Newsome, TP., Asling, B., Dickson, BJ., Suzuki, T. (2008) Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system. PLoS Genet. 4(5):e1000085

Bortfeldt, R., Schindler, S., Szafranski, K., Schuster, S., Holste, D. (2008) Comparative analysis of sequence features involved in the recognition of tandem splice sites. BMC Genomics. 9:202

Bowman, SK., Rolland, V., Betschinger, J., Kinsey, KA., Emery, G., Knoblich, JA. (2008) The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell. 14(4):535-46

Bozec, A., Bakiri, L., Hoebertz, A., Eferl, R., Schilling, AF., Komnenovic, V., Scheuch, H., Priemel, M., Stewart, CL., Amling, M., Wagner, EF. (2008) Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia. Nature. 454(7201):221-5

Breitsprecher, D., Kiesewetter, AK., Linkner, J., Urbanke, C., Resch, GP., Small, JV., Faix, J. (2008) Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation. EMBO J. 27(22):2943-54

Chen, D., Ahlford, A., Schnorrer, F., Kalchhauser, I., Fellner, M., Viràgh, E., Kiss, I., Syvänen, AC., Dickson, BJ. (2008) High-resolution, high-throughput SNP mapping in Drosophila melanogaster. Nat Methods. 5(4):323-9

Cobaleda, C., Busslinger, M. (2008) Developmental plasticity of lymphocytes. Curr Opin Immunol. 20(2):139-48

d'Erfurth, I., Jolivet, S., Froger, N., Catrice, O., Novatchkova, M., Simon, M., Jenczewski, E., Mercier, R. (2008) Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to the production of diploid pollen grains. PLoS Genet. 4(11):e1000274

Datta, SR., Vasconcelos, ML., Ruta, V., Luo, S., Wong, A., Demir, E., Flores, J., Balonze, K., Dickson, BJ., Axel, R. (2008) The Drosophila pheromone cVA activates a sexually dimorphic neural circuit. Nature. 452(7186):473-7

de la Fuente van Bentem, S., Anrather, D., Dohnal, I., Roitinger, E., Csaszar, E., Joore, J., Buijnink, J., Carreri, A., Forzani, C., Lorkovic, ZJ., Barta, A., Lecourieux, D., Verhounig, A., Jonak, C., Hirt, H. (2008) Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis. J Proteome Res. 7(6):2458-70

Dickson, BJ. (2008) Wired for sex: the neurobiology of Drosophila mating decisions. Science. 322(5903):904-9

Durchdewald, M., Guinea-Viniegra, J., Haag, D., Riehl, A., Lichter, P., Hahn, M., Wagner, EF., Angel, P., Hess, J. (2008) Podoplanin is a novel fos target gene in skin carcinogenesis. Cancer Res. 68(17):6877-83

Eferl, R., Hasselblatt, P., Rath, M., Popper, H., Zenz, R., Komnenovic, V., Idarraga, MH., Kenner, L., Wagner, EF. (2008) Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1. Proc Natl Acad Sci U S A. 105(30):10525-30

Ferrer-Vaquer, A., Maurey, P., Werzowa, J., Firnberg, N., Leibbrandt, A., Neubüser, A. (2008) Expression and regulation of HTRA1 during chick and early mouse development. Dev Dyn. 237(7):1893-900

Fujimori, S., Kostanova Poliakova, D., Hartmann C. (2008) Role of Growth factors in Bone development and differentiation. In: The Skeletal System. Ed. Pourquie, O. Cold Spring Harbor Laboratory Press, New York. Chapter:8

Gal, A., Sjöblom, T., Fedorova, L., Imreh, S., Beug, H., Moustakas, A. (2008) Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis. Oncogene. 27(9):1218-30

Gerlitz, O., Wagner, EF., Moreno, E. (2008) When flies and mice develop cancer. Meeting on development and cancer. EMBO Rep. 9(8):730-4

Gilestro, GF. (2008) Redundant mechanisms for regulation of midline crossing in Drosophila. PLoS One. 3(11):e3798

Graf, T., Busslinger, M. (2008) B young again. Immunity. 28(5):606-8

Grebien, F., Kerenyi, MA., Kovacic, B., Kolbe, T., Becker, V., Dolznig, H., Pfeffer, K., Klingmüller, U., Müller, M., Beug, H., Müllner, EW., Moriggl, R. (2008) Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood. 111(9):4511-22

Grech, G., Blázquez-Domingo, M., Kolbus, A., Bakker, WJ., Müllner, EW., Beug, H., von Lindern, M. (2008) Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation. Blood. 112(7):2750-60

Greeson, NT., Sengupta, R., Arida, AR., Jenuwein, T., Sanders, SL. (2008) Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage. J Biol Chem. 283(48):33168-74

Grishchuk, EL., Efremov, AK., Volkov, VA., Spiridonov, IS., Gudimchuk, N., Westermann, S., Drubin, D., Barnes, G., McIntosh, JR., Ataullakhanov, FI. (2008) The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion. Proc Natl Acad Sci U S A. 105(40):15423-8

Grishchuk, EL., Spiridonov, IS., Volkov, VA., Efremov, A., Westermann, S., Drubin, D., Barnes, G., Ataullakhanov, FI., McIntosh, JR. (2008) Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms. Proc Natl Acad Sci U S A. 105(19):6918-23

Grote, D., Boualia, SK., Souabni, A., Merkel, C., Chi, X., Costantini, F., Carroll, T., Bouchard, M. (2008) Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction. PLoS Genet. 4(12):e1000316

Guo, F., Tänzer, S., Busslinger, M., Weih, F. (2008) Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis. Blood. 112(3):551-9

Gurzov, EN., Bakiri, L., Alfaro, JM., Wagner, EF., Izquierdo, M. (2008) Targeting c-Jun and JunB proteins as potential anticancer cell therapy. Oncogene. 27(5):641-52

Gurzov, EN., Ortis, F., Bakiri, L., Wagner, EF., Eizirik, DL. (2008) JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells. PLoS One. 3(8):e3030

Hasselblatt, P., Gresh, L., Kudo, H., Guinea-Viniegra, J., Wagner, EF. (2008) The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice. Oncogene. 27(47):6102-9

Hoffmann, E., Ashouri, J., Wolter, S., Doerrie, A., Dittrich-Breiholz, O., Schneider, H., Wagner, EF., Troppmair, J., Mackman, N., Kracht, M. (2008) Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway. J Biol Chem. 283(18):12120-8

Holste, D., Ohler, U. (2008) Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events. PLoS Comput Biol. 4(1):e21

Hui, L., Zatloukal, K., Scheuch, H., Stepniak, E., Wagner, EF. (2008) Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation. J Clin Invest.

Jiao, X., Katiyar, S., Liu, M., Mueller, SC., Lisanti, MP., Li, A., Pestell, TG., Wu, K., Ju, X., Li, Z., Wagner, EF., Takeya, T., Wang, C., Pestell, RG. (2008) Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Mol Biol Cell. 19(4):1378-90

Kastner, B., Fischer, N., Golas, MM., Sander, B., Dube, P., Boehringer, D., Hartmuth, K., Deckert, J., Hauer, F., Wolf, E., Uchtenhagen, H., Urlaub, H., Herzog, F., Peters, JM., Poerschke, D., Lührmann, R., Stark, H. (2008) GraFix: sample preparation for single-particle electron cryomicroscopy. Nat Methods. 5(1):53-5

Kawamata, A., Izu, Y., Yokoyama, H., Amagasa, T., Wagner, EF., Nakashima, K., Ezura, Y., Hayata, T., Noda, M. (2008) JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion. J Cell Biochem. 103(4):1037-45

Kerenyi, MA., Grebien, F., Gehart, H., Schifrer, M., Artaker, M., Kovacic, B., Beug, H., Moriggl, R., Müllner, EW. (2008) Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. Blood. 112(9):3878-88

Koch, B., Kueng, S., Ruckenbauer, C., Wendt, KS., Peters, JM. (2008) The Suv39h-HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells. Chromosoma. 117(2):199-210

Kolev, V., Mandinova, A., Guinea-Viniegra, J., Hu, B., Lefort, K., Lambertini, C., Neel, V., Dummer, R., Wagner, EF., Dotto, GP. (2008) EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer. Nat Cell Biol. 10(8):902-11

Kornfeld, JW., Grebien, F., Kerenyi, MA., Friedbichler, K., Kovacic, B., Zankl, B., Hoelbl, A., Nivarti, H., Beug, H., Sexl, V., Muller, M., Kenner, L., Mullner, EW., Gouilleux, F., Moriggl, R. (2008) The different functions of Stat5 and chromatin alteration through Stat5 proteins. Front Biosci. 13:6237-54

Kragl, M., Knapp, D., Nacu, E., Khattak, S., Schnapp, E., Epperlein, HH., Tanaka, EM. (2008) Novel insights into the flexibility of cell and positional identity during urodele limb regeneration. Cold Spring Harb Symp Quant Biol. 73:583-92

Krojer, T., Pangerl, K., Kurt, J., Sawa, J., Stingl, C., Mechtler, K., Huber, R., Ehrmann, M., Clausen, T. (2008) Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A. 105(22):7702-7

Krojer, T., Sawa, J., Schäfer, E., Saibil, HR., Ehrmann, M., Clausen, T. (2008) Structural basis for the regulated protease and chaperone function of DegP. Nature. 453(7197):885-90

Kwon, K., Hutter, C., Sun, Q., Bilic, I., Cobaleda, C., Malin, S., Busslinger, M. (2008) Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development. Immunity. 28(6):751-62

Lynch, SL., Boon, AJ., Smith, J., Harper, CM., Tanaka, EM. (2008) Complications of needle electromyography: hematoma risk and correlation with anticoagulation and antiplatelet therapy. Muscle Nerve. 38(4):1225-30

Macaisne, N., Novatchkova, M., Peirera, L., Vezon, D., Jolivet, S., Froger, N., Chelysheva, L., Grelon, M., Mercier, R. (2008) SHOC1, an XPF endonuclease-related protein, is essential for the formation of class I meiotic crossovers. Curr Biol. 18(18):1432-7

Meixner, A., Zenz, R., Schonthaler, HB., Kenner, L., Scheuch, H., Penninger, JM., Wagner, EF. (2008) Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation. Nat Cell Biol. 10(8):1003-11

Meltzer, M., Hasenbein, S., Hauske, P., Kucz, N., Merdanovic, M., Grau, S., Beil, A., Jones, D., Krojer, T., Clausen, T., Ehrmann, M., Kaiser, M. (2008) Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control. Angew Chem Int Ed Engl. 47(7):1332-4

Mikula M., Lahsnig C., Fischer A.N.M., Proell V., Huber H., Fuchs E., Eger A., Beug H., Mikulits W. (2008) Epithelial Plasticity of Hepatocytes During Liver Tumor Progression Stem Cells and their Potential for Clinical Application . :123-135

Mochizuki, K., Novatchkova, M., Loidl, J. (2008) DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena. J Cell Sci. 121(Pt 13):2148-58

Naetar, N., Korbei, B., Kozlov, S., Kerenyi, MA., Dorner, D., Kral, R., Gotic, I., Fuchs, P., Cohen, TV., Bittner, R., Stewart, CL., Foisner, R. (2008) Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation. Nat Cell Biol. 10(11):1341-8

Nedjic, J., Aichinger, M., Emmerich, J., Mizushima, N., Klein, L. (2008) Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature. 455(7211):396-400

Neumüller, RA., Betschinger, J., Fischer, A., Bushati, N., Poernbacher, I., Mechtler, K., Cohen, SM., Knoblich, JA. (2008) Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage. Nature. 454(7201):241-5

Pannetier, M., Julien, E., Schotta, G., Tardat, M., Sardet, C., Jenuwein, T., Feil, R. (2008) PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse. EMBO Rep. 9(10):998-1005

Pauli, A., Althoff, F., Oliveira, RA., Heidmann, S., Schuldiner, O., Lehner, CF., Dickson, BJ., Nasmyth, K. (2008) Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons. Dev Cell. 14(2):239-51

Peters, JM. (2008) Checkpoint control: the journey continues. Curr Biol. 18(4):R170-2

Peters, JM., Tedeschi, A., Schmitz, J. (2008) The cohesin complex and its roles in chromosome biology. Genes Dev. 22(22):3089-114

Petronczki, M., Lénárt, P., Peters, JM. (2008) Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1. Dev Cell. 14(5):646-59

Pinent, M., Hackl, H., Burkard, TR., Prokesch, A., Papak, C., Scheideler, M., Hämmerle, G., Zechner, R., Trajanoski, Z., Strauss, JG. (2008) Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice. Genomics. 92(1):26-32

Poser, I., Sarov, M., Hutchins, JR., Hériché, JK., Toyoda, Y., Pozniakovsky, A., Weigl, D., Nitzsche, A., Hegemann, B., Bird, AW., Pelletier, L., Kittler, R., Hua, S., Naumann, R., Augsburg, M., Sykora, MM., Hofemeister, H., Zhang, Y., Nasmyth, K., White, KP., Dietzel, S., Mechtler, K., Durbin, R., Stewart, AF., Peters, JM., Buchholz, F., Hyman, AA. (2008) BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals. Nat Methods. 5(5):409-15

Riehs, N., Akimcheva, S., Puizina, J., Bulankova, P., Idol, RA., Siroky, J., Schleiffer, A., Schweizer, D., Shippen, DE., Riha, K. (2008) Arabidopsis SMG7 protein is required for exit from meiosis. J Cell Sci. 121(Pt 13):2208-16

Ruiz-Bonilla, V., Perdiguero, E., Gresh, L., Serrano, AL., Zamora, M., Sousa-Victor, P., Jardí, M., Wagner, EF., Muñoz-Cánoves, P. (2008) Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases. Cell Cycle. 7(14):2208-14

Schähs, P., Weidinger, P., Probst, OC., Svoboda, B., Stadlmann, J., Beug, H., Waerner, T., Mach, L. (2008) Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis. Exp Cell Res. 314(16):3036-47

Schmidt, A., Csaszar, E., Ammerer, G., Mechtler, K. (2008) Enhanced detection and identification of multiply phosphorylated peptides using TiO2 enrichment in combination with MALDI TOF/TOF MS. Proteomics. 8(21):4577-92

Schnorrer, F., Ahlford, A., Chen, D., Milani, L., Syvänen, AC. (2008) Positional cloning by fast-track SNP-mapping in Drosophila melanogaster. Nat Protoc. 3(11):1751-65

Schotta, G., Sengupta, R., Kubicek, S., Malin, S., Kauer, M., Callén, E., Celeste, A., Pagani, M., Opravil, S., De La Rosa-Velazquez, IA., Espejo, A., Bedford, MT., Nussenzweig, A., Busslinger, M., Jenuwein, T. (2008) A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes Dev. 22(15):2048-61

Shibata, S., Wutz, A. (2008) Transcript versus transcription? Epigenetics. 3(5):246-9

Shibata, S., Yokota, T., Wutz, A. (2008) Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation. EMBO J. 27(13):1816-26

Small, JV., Auinger, S., Nemethova, M., Koestler, S., Goldie, KN., Hoenger, A., Resch, GP. (2008) Unravelling the structure of the lamellipodium. J Microsc. 231(3):479-85

Tanaka, EM., Sato, S. (2008) Longitudinal alteration of the occlusal plane and development of different dentoskeletal frames during growth. Am J Orthod Dentofacial Orthop. 134(5):602.e1-11; discussion 602-3

Tanaka, EM., Weidinger, G. (2008) Micromanaging regeneration. Genes Dev. 22(6):700-5

Tanaka, EM., Weidinger, G. (2008) Heads or tails: can Wnt tell which one is up? Nat Cell Biol. 10(2):122-4

Taschner, MJ., Rafigh, M., Lampert, F., Schnaiter, S., Hartmann, C. (2008) Ca2+/Calmodulin-dependent kinase II signaling causes skeletal overgrowth and premature chondrocyte maturation. Dev Biol. 317(1):132-46

Taylor, S., Peters, JM. (2008) Polo and Aurora kinases: lessons derived from chemical biology. Curr Opin Cell Biol. 20(1):77-84

Tomasi, T., Hakeda-Suzuki, S., Ohler, S., Schleiffer, A., Suzuki, T. (2008) The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions. Neuron. 57(5):691-704

Vernos, I., Peters, JM. (2008) Twenty years of cell-cycle conferences in Roscoff. Nat Cell Biol. 10(8):877-80

Wada, T., Stepniak, E., Hui, L., Leibbrandt, A., Katada, T., Nishina, H., Wagner, EF., Penninger, JM. (2008) Antagonistic control of cell fates by JNK and p38-MAPK signaling. Cell Death Differ. 15(1):89-93

Wagner, EF. (2008) Developmentally informed research on the effectiveness of clinical trials: a primer for assessing how developmental issues may influence treatment responses among adolescents with alcohol use problems. Pediatrics. 121 Suppl 4:S337-47

Wang, HW., Long, S., Ciferri, C., Westermann, S., Drubin, D., Barnes, G., Nogales, E. (2008) Architecture and flexibility of the yeast Ndc80 kinetochore complex. J Mol Biol. 383(4):894-903

Wendt, KS., Yoshida, K., Itoh, T., Bando, M., Koch, B., Schirghuber, E., Tsutsumi, S., Nagae, G., Ishihara, K., Mishiro, T., Yahata, K., Imamoto, F., Aburatani, H., Nakao, M., Imamoto, N., Maeshima, K., Shirahige, K., Peters, JM. (2008) Cohesin mediates transcriptional insulation by CCCTC-binding factor. Nature. 451(7180):796-801

Winter, S., Simboeck, E., Fischle, W., Zupkovitz, G., Dohnal, I., Mechtler, K., Ammerer, G., Seiser, C. (2008) 14-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation. EMBO J. 27(1):88-99

Wolter, S., Doerrie, A., Weber, A., Schneider, H., Hoffmann, E., von der Ohe, J., Bakiri, L., Wagner, EF., Resch, K., Kracht, M. (2008) c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene. Mol Cell Biol. 28(13):4407-23

Yapici, N., Kim, YJ., Ribeiro, C., Dickson, BJ. (2008) A receptor that mediates the post-mating switch in Drosophila reproductive behaviour. Nature. 451(7174):33-7

Yotova, IY., Vlatkovic, IM., Pauler, FM., Warczok, KE., Ambros, PF., Oshimura, M., Theussl, HC., Gessler, M., Wagner, EF., Barlow, DP. (2008) Identification of the human homolog of the imprinted mouse Air non-coding RNA. Genomics. 92(6):464-73

Yu, JY., Dickson, BJ. (2008) Neuroscience: hidden female talent. Nature. 453(7191):41-2

Zenz, R., Eferl, R., Scheinecker, C., Redlich, K., Smolen, J., Schonthaler, HB., Kenner, L., Tschachler, E., Wagner, EF. (2008) Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease. Arthritis Res Ther. 10(1):201

2007

Aigner, K., Dampier, B., Descovich, L., Mikula, M., Sultan, A., Schreiber, M., Mikulits, W., Brabletz, T., Strand, D., Obrist, P., Sommergruber, W., Schweifer, N., Wernitznig, A., Beug, H., Foisner, R., Eger, A. (2007) The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene. 26(49):6979-88

Aigner, K., Descovich, L., Mikula, M., Sultan, A., Dampier, B., Bonné, S., van Roy, F., Mikulits, W., Schreiber, M., Brabletz, T., Sommergruber, W., Schweifer, N., Wernitznig, A., Beug, H., Foisner, R., Eger, A. (2007) The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. FEBS Lett. 581(8):1617-24

Amsen, D., Antov, A., Jankovic, D., Sher, A., Radtke, F., Souabni, A., Busslinger, M., McCright, B., Gridley, T., Flavell, RA. (2007) Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity. 27(1):89-99

Andrade, N., Komnenovic, V., Blake, SM., Jossin, Y., Howell, B., Goffinet, A., Schneider, WJ., Nimpf, J. (2007) ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin. Proc Natl Acad Sci U S A. 104(20):8508-13

Aschenbrenner, K., D'Cruz, LM., Vollmann, EH., Hinterberger, M., Emmerich, J., Swee, LK., Rolink, A., Klein, L. (2007) Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nat Immunol. 8(4):351-8

Bakiri, L., Takada, Y., Radolf, M., Eferl, R., Yaniv, M., Wagner, EF., Matsuo, K. (2007) Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation. Bone. 40(4):867-75

Bakker, WJ., van Dijk, TB., Parren-van Amelsvoort, M., Kolbus, A., Yamamoto, K., Steinlein, P., Verhaak, RG., Mak, TW., Beug, H., Löwenberg, B., von Lindern, M. (2007) Differential regulation of Foxo3a target genes in erythropoiesis. Mol Cell Biol. 27(10):3839-3854

Benetti, R., Gonzalo, S., Jaco, I., Schotta, G., Klatt, P., Jenuwein, T., Blasco, MA. (2007) Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol. 178(6):925-36

Bruce, SJ., Rea, RW., Steptoe, AL., Busslinger, M., Bertram, JF., Perkins, AC. (2007) In vitro differentiation of murine embryonic stem cells toward a renal lineage. Differentiation. 75(5):337-49

Burkard, T. R., Trajanoski, Z., Novatchkova, M., Hackl, H., Eisenhaber, F. (2007) Identification of new targets using expression profiling. In Antiangiogenic cancer therapy (Davis, D.R., Herbst, R.S., & Abbruzzese, J.L., eds.); CRC Press Taylor & Francis Group, Boca Raton London New York.. :415-41

Casalino, L., Bakiri, L., Talotta, F., Weitzman, JB., Fusco, A., Yaniv, M., Verde, P. (2007) Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription. EMBO J. 26(7):1878-90

Cobaleda, C., Jochum, W., Busslinger, M. (2007) Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors. Nature. 449(7161):473-7

Cobaleda, C., Schebesta, A., Delogu, A., Busslinger, M. (2007) Pax5: the guardian of B cell identity and function. Nat Immunol. 8(5):463-70

Cowan, C. (2007) Ran and Rac in mouse eggs: cortical polarity and spindle positioning. Dev Cell. 12(2):174-6

Cowan, CR., Hyman, AA. (2007) Acto-myosin reorganization and PAR polarity in C. elegans. Development. 134(6):1035-43

Dickson, BJ., Moser, EI. (2007) Neurobiology of behaviour. Curr Opin Neurobiol. 17(6):672-4

Dietzl, G., Chen, D., Schnorrer, F., Su, KC., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., Couto, A., Marra, V., Keleman, K., Dickson, BJ. (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature. 448(7150):151-6

Eferl, R., Zenz, R., Theussl, HC., Wagner, EF. (2007) Simultaneous generation of fra-2 conditional and fra-2 knock-out mice. Genesis. 45(7):447-51

Ehrlich, I., Klein, M., Rumpel, S., Malinow, R. (2007) PSD-95 is required for activity-driven synapse stabilization. Proc Natl Acad Sci U S A. 104(10):4176-81

Eisenhaber, B., Chumak, N., Eisenhaber, F., Hauser, MT. (2007) The ring between ring fingers (RBR) protein family. Genome Biol. 8(3):209

Eisenhaber, B., Eisenhaber, F. (2007) Posttranslational modifications and subcellular localization signals: indicators of sequence regions without inherent 3D structure? Curr Protein Pept Sci. 8(2):197-203

Engblom, D., Kornfeld, JW., Schwake, L., Tronche, F., Reimann, A., Beug, H., Hennighausen, L., Moriggl, R., Schütz, G. (2007) Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. Genes Dev. 21(10):1157-62

Fischer, AN., Fuchs, E., Mikula, M., Huber, H., Beug, H., Mikulits, W. (2007) PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression. Oncogene. 26(23):3395-405

Fuxa, M., Busslinger, M. (2007) Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol. 178(12):8222-8

Fuxa, M., Busslinger, M. (2007) Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function. J Immunol. 178(5):3031-7

Gebeshuber, CA., Sladecek, S., Grunert, S. (2007) Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs. Cells Tissues Organs. 185(1-3):51-60

Gillardon, F., Kloss, A., Berg, M., Neumann, M., Mechtler, K., Hengerer, B., Dahlmann, B. (2007) The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity. J Neurochem. 101(6):1483-90

Gregan, J., Riedel, CG., Petronczki, M., Cipak, L., Rumpf, C., Poser, I., Buchholz, F., Mechtler, K., Nasmyth, K. (2007) Tandem affinity purification of functional TAP-tagged proteins from human cells. Nat Protoc. 2(5):1145-51

Gregan, J., Riedel, CG., Pidoux, AL., Katou, Y., Rumpf, C., Schleiffer, A., Kearsey, SE., Shirahige, K., Allshire, RC., Nasmyth, K. (2007) The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation. Curr Biol. 17(14):1190-200

Hanahan, D., Wagner, EF., Palmiter, RD. (2007) The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer. Genes Dev. 21(18):2258-70

Harir, N., Pecquet, C., Kerenyi, M., Sonneck, K., Kovacic, B., Nyga, R., Brevet, M., Dhennin, I., Gouilleux-Gruart, V., Beug, H., Valent, P., Lassoued, K., Moriggl, R., Gouilleux, F. (2007) Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias. Blood. 109(4):1678-86

Hartler, J., Thallinger, GG., Stocker, G., Sturn, A., Burkard, TR., Körner, E., Rader, R., Schmidt, A., Mechtler, K., Trajanoski, Z. (2007) MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data. BMC Bioinformatics. 8:197

Hartmann, C. (2007) Skeletal development--Wnts are in control. Mol Cells. 24(2):177-84

Hasselblatt, H., Kurzbauer, R., Wilken, C., Krojer, T., Sawa, J., Kurt, J., Kirk, R., Hasenbein, S., Ehrmann, M., Clausen, T. (2007) Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress. Genes Dev. 21(20):2659-70

Hasselblatt, P., Rath, M., Komnenovic, V., Zatloukal, K., Wagner, EF. (2007) Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase. Proc Natl Acad Sci U S A. 104(43):17105-10

Hattori, D., Demir, E., Kim, HW., Viragh, E., Zipursky, SL., Dickson, BJ. (2007) Dscam diversity is essential for neuronal wiring and self-recognition. Nature. 449(7159):223-7

Herzig, M., Savarese, F., Novatchkova, M., Semb, H., Christofori, G. (2007) Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling. Oncogene. 26(16):2290-8

Huang, J., Sengupta, R., Espejo, AB., Lee, MG., Dorsey, JA., Richter, M., Opravil, S., Shiekhattar, R., Bedford, MT., Jenuwein, T., Berger, SL. (2007) p53 is regulated by the lysine demethylase LSD1. Nature. 449(7158):105-8

Hui, L., Bakiri, L., Mairhorfer, A., Schweifer, N., Haslinger, C., Kenner, L., Komnenovic, V., Scheuch, H., Beug, H., Wagner, EF. (2007) p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet. 39(6):741-9

Hui, L., Bakiri, L., Stepniak, E., Wagner, EF. (2007) p38alpha: a suppressor of cell proliferation and tumorigenesis. Cell Cycle. 6(20):2429-33

Ivanov, D., Nasmyth, K. (2007) A physical assay for sister chromatid cohesion in vitro. Mol Cell. 27(2):300-10

Jantsch, V., Tang, L., Pasierbek, P., Penkner, A., Nayak, S., Baudrimont, A., Schedl, T., Gartner, A., Loidl, J. (2007) Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing. Mol Biol Cell. 18(12):4911-20

Jiménez, JL., Hegemann, B., Hutchins, JR., Peters, JM., Durbin, R. (2007) A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database. Genome Biol. 8(5):R90

Kappen, C., Neubüser, A., Balling, R., Finnell, R. (2007) Molecular basis for skeletal variation: insights from developmental genetic studies in mice. Birth Defects Res B Dev Reprod Toxicol. 80(6):425-50

Katiyar, S., Jiao, X., Wagner, E., Lisanti, MP., Pestell, RG. (2007) Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor. Mol Cell Biol. 27(4):1356-69

Keene, AC., Waddell, S. (2007) Drosophila olfactory memory: single genes to complex neural circuits. Nat Rev Neurosci. 8(5):341-54

Keleman, K., Krüttner, S., Alenius, M., Dickson, BJ. (2007) Function of the Drosophila CPEB protein Orb2 in long-term courtship memory. Nat Neurosci. 10(12):1587-93

Kuba, K., Zhang, L., Imai, Y., Arab, S., Chen, M., Maekawa, Y., Leschnik, M., Leibbrandt, A., Markovic, M., Makovic, M., Schwaighofer, J., Beetz, N., Musialek, R., Neely, GG., Komnenovic, V., Kolm, U., Metzler, B., Ricci, R., Hara, H., Meixner, A., Nghiem, M., Chen, X., Dawood, F., Wong, KM., Sarao, R., Cukerman, E., Kimura, A., Hein, L., Thalhammer, J., Liu, PP., Penninger, JM. (2007) Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload. Circ Res. 101(4):e32-42

Kubicek, S., O'Sullivan, RJ., August, EM., Hickey, ER., Zhang, Q., Teodoro, ML., Rea, S., Mechtler, K., Kowalski, JA., Homon, CA., Kelly, TA., Jenuwein, T. (2007) Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol Cell. 25(3):473-81

Kurtovic, A., Widmer, A., Dickson, BJ. (2007) A single class of olfactory neurons mediates behavioural responses to a Drosophila sex pheromone. Nature. 446(7135):542-6

Leeb, M., Wutz, A. (2007) Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells. J Cell Biol. 178(2):219-29

Lénárt, P., Petronczki, M., Steegmaier, M., Di Fiore, B., Lipp, JJ., Hoffmann, M., Rettig, WJ., Kraut, N., Peters, JM. (2007) The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr Biol. 17(4):304-15

Lipp, JJ., Hirota, T., Poser, I., Peters, JM. (2007) Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes. J Cell Sci. 120(Pt 7):1245-55

Lööf, S., Straube, WL., Drechsel, D., Tanaka, EM., Simon, A. (2007) Plasticity of mammalian myotubes upon stimulation with a thrombin-activated serum factor. Cell Cycle. 6(9):1096-101

Magnusson, M., Brun, AC., Miyake, N., Larsson, J., Ehinger, M., Bjornsson, JM., Wutz, A., Sigvardsson, M., Karlsson, S. (2007) HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development. Blood. 109(9):3687-96

Martinez, J., Busslinger, M. (2007) Life beyond cleavage: the case of Ago2 and hematopoiesis. Genes Dev. 21(16):1983-8

Maurer-Stroh, S., Koranda, M., Benetka, W., Schneider, G., Sirota, FL., Eisenhaber, F. (2007) Towards complete sets of farnesylated and geranylgeranylated proteins. PLoS Comput Biol. 3(4):e66

Mazanek, M., Mituloviae, G., Herzog, F., Stingl, C., Hutchins, JR., Peters, JM., Mechtler, K. (2007) Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis. Nat Protoc. 2(5):1059-69

McGarvey, KM., Greene, E., Fahrner, JA., Jenuwein, T., Baylin, SB. (2007) DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2. Cancer Res. 67(11):5097-102

McHedlishvili, L., Epperlein, HH., Telzerow, A., Tanaka, EM. (2007) A clonal analysis of neural progenitors during axolotl spinal cord regeneration reveals evidence for both spatially restricted and multipotent progenitors. Development. 134(11):2083-93

Naetar, N., Hutter, S., Dorner, D., Dechat, T., Korbei, B., Gotzmann, J., Beug, H., Foisner, R. (2007) LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J Cell Sci. 120(Pt 5):737-47

Nakajima, M., Kumada, K., Hatakeyama, K., Noda, T., Peters, JM., Hirota, T. (2007) The complete removal of cohesin from chromosome arms depends on separase. J Cell Sci. 120(Pt 23):4188-96

Neuberger, G., Schneider, G., Eisenhaber, F. (2007) pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model. Biol Direct. 2:1

Ng, K., Pullirsch, D., Leeb, M., Wutz, A. (2007) Xist and the order of silencing. EMBO Rep. 8(1):34-9

Obernosterer, G., Martinez, J., Alenius, M. (2007) Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat Protoc. 2(6):1508-14

Ohm, JE., McGarvey, KM., Yu, X., Cheng, L., Schuebel, KE., Cope, L., Mohammad, HP., Chen, W., Daniel, VC., Yu, W., Berman, DM., Jenuwein, T., Pruitt, K., Sharkis, SJ., Watkins, DN., Herman, JG., Baylin, SB. (2007) A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 39(2):237-42

Ott, RG., Simma, O., Kollmann, K., Weisz, E., Zebedin, EM., Schorpp-Kistner, M., Heller, G., Zöchbauer, S., Wagner, EF., Freissmuth, M., Sexl, V. (2007) JunB is a gatekeeper for B-lymphoid leukemia. Oncogene. 26(33):4863-71

Pasquali, C., Bertschy-Meier, D., Chabert, C., Curchod, ML., Arod, C., Booth, R., Mechtler, K., Vilbois, F., Xenarios, I., Ferguson, CG., Prestwich, GD., Camps, M., Rommel, C. (2007) A chemical proteomics approach to phosphatidylinositol 3-kinase signaling in macrophages. Mol Cell Proteomics. 6(11):1829-41

Penkner, A., Portik-Dobos, Z., Tang, L., Schnabel, R., Novatchkova, M., Jantsch, V., Loidl, J. (2007) A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination. EMBO J. 26(24):5071-82

Penkner, A., Tang, L., Novatchkova, M., Ladurner, M., Fridkin, A., Gruenbaum, Y., Schweizer, D., Loidl, J., Jantsch, V. (2007) The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis. Dev Cell. 12(6):873-85

Perdiguero, E., Ruiz-Bonilla, V., Gresh, L., Hui, L., Ballestar, E., Sousa-Victor, P., Baeza-Raja, B., Jardí, M., Bosch-Comas, A., Esteller, M., Caelles, C., Serrano, AL., Wagner, EF., Muñoz-Cánoves, P. (2007) Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation. EMBO J. 26(5):1245-56

Peters, JM. (2007) Cell biology: the checkpoint brake relieved. Nature. 446(7138):868-9

Petronczki, M., Glotzer, M., Kraut, N., Peters, JM. (2007) Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev Cell. 12(5):713-25

Rath, O., Himmler, A., Baum, A., Sommergruber, W., Beug, H., Metz, T. (2007) c-Myc is required for transformation of FDC-P1 cells by EGFRvIII. FEBS Lett. 581(13):2549-56

Regha, K., Sloane, MA., Huang, R., Pauler, FM., Warczok, KE., Melikant, B., Radolf, M., Martens, JH., Schotta, G., Jenuwein, T., Barlow, DP. (2007) Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome. Mol Cell. 27(3):353-66

Roessler, S., Györy, I., Imhof, S., Spivakov, M., Williams, RR., Busslinger, M., Fisher, AG., Grosschedl, R. (2007) Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5. Mol Cell Biol. 27(2):579-94

Rudolph, T., Yonezawa, M., Lein, S., Heidrich, K., Kubicek, S., Schäfer, C., Phalke, S., Walther, M., Schmidt, A., Jenuwein, T., Reuter, G. (2007) Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3. Mol Cell. 26(1):103-15

Schebesta, A., McManus, S., Salvagiotto, G., Delogu, A., Busslinger, GA., Busslinger, M. (2007) Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function. Immunity. 27(1):49-63

Schittenhelm, RB., Heeger, S., Althoff, F., Walter, A., Heidmann, S., Mechtler, K., Lehner, CF. (2007) Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes. Chromosoma. 116(4):385-402

Schmitz, J., Watrin, E., Lénárt, P., Mechtler, K., Peters, JM. (2007) Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase. Curr Biol. 17(7):630-6

Schnorrer, F., Kalchhauser, I., Dickson, BJ. (2007) The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila. Dev Cell. 12(5):751-66

Schulz, DM., Kalkhof, S., Schmidt, A., Ihling, C., Stingl, C., Mechtler, K., Zschörnig, O., Sinz, A. (2007) Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high-resolution mass spectrometry, and computational modeling. Proteins. 69(2):254-69

Skok, JA., Gisler, R., Novatchkova, M., Farmer, D., de Laat, W., Busslinger, M. (2007) Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes. Nat Immunol. 8(4):378-87

Souabni, A., Jochum, W., Busslinger, M. (2007) Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus. Blood. 109(1):281-9

Steegmaier, M., Hoffmann, M., Baum, A., Lénárt, P., Petronczki, M., Krssák, M., Gürtler, U., Garin-Chesa, P., Lieb, S., Quant, J., Grauert, M., Adolf, GR., Kraut, N., Peters, JM., Rettig, WJ. (2007) BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo. Curr Biol. 17(4):316-22

Sweeney, LB., Couto, A., Chou, YH., Berdnik, D., Dickson, BJ., Luo, L., Komiyama, T. (2007) Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions. Neuron. 53(2):185-200

Takada, Y., Isono, K., Shinga, J., Turner, JM., Kitamura, H., Ohara, O., Watanabe, G., Singh, PB., Kamijo, T., Jenuwein, T., Burgoyne, PS., Koseki, H. (2007) Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes. Development. 134(3):579-90

Tsareva, SA., Moriggl, R., Corvinus, FM., Wiederanders, B., Schütz, A., Kovacic, B., Friedrich, K. (2007) Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction. Neoplasia. 9(4):279-91

Uanschou, C., Siwiec, T., Pedrosa-Harand, A., Kerzendorfer, C., Sanchez-Moran, E., Novatchkova, M., Akimcheva, S., Woglar, A., Klein, F., Schlögelhofer, P. (2007) A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene. EMBO J. 26(24):5061-70

Villa, R., Pasini, D., Gutierrez, A., Morey, L., Occhionorelli, M., Viré, E., Nomdedeu, JF., Jenuwein, T., Pelicci, PG., Minucci, S., Fuks, F., Helin, K., Di Croce, L. (2007) Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell. 11(6):513-25

Vogel, J., Weigand, MA., Behrens, A., Wagner, EF., Schorpp-Kistner, M., Zimmermann, M., Schenkel, J. (2007) Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action. Brain Res. 1151:12-9

Watrin, E., Peters, JM. (2007) Molecular biology. How and when the genome sticks together. Science. 317(5835):209-10

Wiesenberger, G., Speer, F., Haller, G., Bonnefoy, N., Schleiffer, A., Schafer, B. (2007) RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes. J Mol Biol. 367(3):681-91

Wisniewska, MB., Ameyar-Zazoua, M., Bakiri, L., Kaminska, B., Yaniv, M., Weitzman, JB. (2007) Dimer composition and promoter context contribute to functional cooperation between AP-1 and NFAT. J Mol Biol. 371(3):569-76

Wissmann, M., Yin, N., Müller, JM., Greschik, H., Fodor, BD., Jenuwein, T., Vogler, C., Schneider, R., Günther, T., Buettner, R., Metzger, E., Schüle, R. (2007) Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat Cell Biol. 9(3):347-53

Wutz, A. (2007) Xist function: bridging chromatin and stem cells. Trends Genet. 23(9):457-64

Wutz, A., Gribnau, J. (2007) X inactivation Xplained. Curr Opin Genet Dev. 17(5):387-93

Yamashita, T., Yao, Z., Li, F., Zhang, Q., Badell, IR., Schwarz, EM., Takeshita, S., Wagner, EF., Noda, M., Matsuo, K., Xing, L., Boyce, BF. (2007) NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1. J Biol Chem. 282(25):18245-53

2006

Abzhanov, A., Kuo, WP., Hartmann, C., Grant, BR., Grant, PR., Tabin, CJ. (2006) The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches. Nature. 442(7102):563-7

Allis, D., Jenuwein, T., Reinberg, D. (Editors), assisted by Caparros, M.L. (2006) Epigenetics Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York..

Arumugam, P., Nishino, T., Haering, CH., Gruber, S., Nasmyth, K. (2006) Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit. Curr Biol. 16(20):1998-2008

Beard, C., Hochedlinger, K., Plath, K., Wutz, A., Jaenisch, R. (2006) Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells. Genesis. 44(1):23-8

Benetka, W., Koranda, M., Eisenhaber, F. (2006) Protein prenylation: an (almost) comprehensive overview on discovery history, enzymology and significance in physiology and disease. Chemical Monthly. 137:1241-1281

Benetka, W., Koranda, M., Maurer-Stroh, S., Pittner, F., Eisenhaber, F. (2006) Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo. BMC Biochem. 7:6

Berdnik, D., Chihara, T., Couto, A., Luo, L. (2006) Wiring stability of the adult Drosophila olfactory circuit after lesion. J Neurosci. 26(13):3367-76

Betschinger, J., Mechtler, K., Knoblich, JA. (2006) Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell. 124(6):1241-53

Bowman, SK., Neumüller, RA., Novatchkova, M., Du, Q., Knoblich, JA. (2006) The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division. Dev Cell. 10(6):731-42

Bradley, SP., Kaminski, DA., Peters, AH., Jenuwein, T., Stavnezer, J. (2006) The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA. J Immunol. 177(2):1179-88

Brankatschk, M., Dickson, BJ. (2006) Netrins guide Drosophila commissural axons at short range. Nat Neurosci. 9(2):188-94

Breithaupt, C., Kurzbauer, R., Lilie, H., Schaller, A., Strassner, J., Huber, R., Macheroux, P., Clausen, T. (2006) Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization. Proc Natl Acad Sci U S A. 103(39):14337-42

Brinkman, AB., Roelofsen, T., Pennings, SW., Martens, JH., Jenuwein, T., Stunnenberg, HG. (2006) Histone modification patterns associated with the human X chromosome. EMBO Rep. 7(6):628-34

Buschhorn, BA., Peters, JM. (2006) How APC/C orders destruction. Nat Cell Biol. 8(3):209-11

Busslinger, M., Tarakhovsky, A. (2006) Epigenetic control of lymphopoiesis. In Epigenetics (Allis, Jenuwein, Reinberg, eds.); Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.. :397-414

Chaumeil, J., Le Baccon, P., Wutz, A., Heard, E. (2006) A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. Genes Dev. 20(16):2223-37

De la Fuente van Bentema S., Roitinger E., Anratherc D., Csaszarc E., Hirt H. (2006) Phosphoproteomics as a tool to unravel plant regulatory mechanisms Physiologia Plantarum . 126(1):110-119

Delogu, A., Schebesta, A., Sun, Q., Aschenbrenner, K., Perlot, T., Busslinger, M. (2006) Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. Immunity. 24(3):269-81

Dickson, BJ., Gilestro, GF. (2006) Regulation of commissural axon pathfinding by slit and its Robo receptors. Annu Rev Cell Dev Biol. 22:651-75

Dolznig, H., Grebien, F., Deiner, EM., Stangl, K., Kolbus, A., Habermann, B., Kerenyi, MA., Kieslinger, M., Moriggl, R., Beug, H., Müllner, EW. (2006) Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR. Oncogene. 25(20):2890-900

Ebert, A., Lein, S., Schotta, G., Reuter, G. (2006) Histone modification and the control of heterochromatic gene silencing in Drosophila. Chromosome Res. 14(4):377-92

Eisenhaber F. (2006) Biomolecular Mechanisms with Computational Biology

Etchegaray, JP., Yang, X., DeBruyne, JP., Peters, AH., Weaver, DR., Jenuwein, T., Reppert, SM. (2006) The polycomb group protein EZH2 is required for mammalian circadian clock function. J Biol Chem. 281(30):21209-15

Fodor, BD., Kubicek, S., Yonezawa, M., O'Sullivan, RJ., Sengupta, R., Perez-Burgos, L., Opravil, S., Mechtler, K., Schotta, G., Jenuwein, T. (2006) Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. Genes Dev. 20(12):1557-62

Fujimura, Y., Isono, K., Vidal, M., Endoh, M., Kajita, H., Mizutani-Koseki, Y., Takihara, Y., van Lohuizen, M., Otte, A., Jenuwein, T., Deschamps, J., Koseki, H. (2006) Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8. Development. 133(12):2371-81

Gerlich, D., Hirota, T., Koch, B., Peters, JM., Ellenberg, J. (2006) Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells. Curr Biol. 16(4):333-44

Gerlich, D., Koch, B., Dupeux, F., Peters, JM., Ellenberg, J. (2006) Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication. Curr Biol. 16(15):1571-8

Gotzmann, J., Fischer, AN., Zojer, M., Mikula, M., Proell, V., Huber, H., Jechlinger, M., Waerner, T., Weith, A., Beug, H., Mikulits, W. (2006) A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene. 25(22):3170-85

Grau, S., Richards, PJ., Kerr, B., Hughes, C., Caterson, B., Williams, AS., Junker, U., Jones, SA., Clausen, T., Ehrmann, M. (2006) The role of human HtrA1 in arthritic disease. J Biol Chem. 281(10):6124-9

Gregan, J., Rabitsch, PK., Rumpf, C., Novatchkova, M., Schleiffer, A., Nasmyth, K. (2006) High-throughput knockout screen in fission yeast. Nat Protoc. 1(5):2457-64

Grote, D., Souabni, A., Busslinger, M., Bouchard, M. (2006) Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development. 133(1):53-61

Gruber, S., Arumugam, P., Katou, Y., Kuglitsch, D., Helmhart, W., Shirahige, K., Nasmyth, K. (2006) Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge. Cell. 127(3):523-37

Haemmerle, G., Lass, A., Zimmermann, R., Gorkiewicz, G., Meyer, C., Rozman, J., Heldmaier, G., Maier, R., Theussl, C., Eder, S., Kratky, D., Wagner, EF., Klingenspor, M., Hoefler, G., Zechner, R. (2006) Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase. Science. 312(5774):734-7

Hartmann, C. (2006) A Wnt canon orchestrating osteoblastogenesis. Trends Cell Biol. 16(3):151-8

Hartmann, C. (2006) Bone and Cartilage. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine (Ganten, Ruckpaul, eds.). :155-9

Hernandez-Hernandez, A., Ray, P., Litos, G., Ciro, M., Ottolenghi, S., Beug, H., Boyes, J. (2006) Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1. EMBO J. 25(14):3264-74

Hess, MW., Pfaller, K., Hampölz, B., Longato, S., Teis, D., Flörl, A., Gutleben, K., Huber, LA. (2006) Microscopy of the Drosophila facet eye: vademecum for standardized fixation, embedding, and sectioning. Microsc Res Tech. 69(2):93-8

Hill, TP., Taketo, MM., Birchmeier, W., Hartmann, C. (2006) Multiple roles of mesenchymal beta-catenin during murine limb patterning. Development. 133(7):1219-29

Hizlan, D., Mishima, M., Tittmann, P., Gross, H., Glotzer, M., Hoenger, A. (2006) Structural analysis of the ZEN-4/CeMKLP1 motor domain and its interaction with microtubules. J Struct Biol. 153(1):73-84

Hoelbl, A., Kovacic, B., Kerenyi, MA., Simma, O., Warsch, W., Cui, Y., Beug, H., Hennighausen, L., Moriggl, R., Sexl, V. (2006) Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood. 107(12):4898-906

Huang, J., Perez-Burgos, L., Placek, BJ., Sengupta, R., Richter, M., Dorsey, JA., Kubicek, S., Opravil, S., Jenuwein, T., Berger, SL. (2006) Repression of p53 activity by Smyd2-mediated methylation. Nature. 444(7119):629-32

Hutterer, A., Berdnik, D., Wirtz-Peitz, F., Zigman, M., Schleiffer, A., Knoblich, JA. (2006) Mitotic activation of the kinase Aurora-A requires its binding partner Bora. Dev Cell. 11(2):147-57

Ihling, C., Schmidt, A., Kalkhof, S., Schulz, DM., Stingl, C., Mechtler, K., Haack, M., Beck-Sickinger, AG., Cooper, DM., Sinz, A. (2006) Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex. J Am Soc Mass Spectrom. 17(8):1100-13

Janda, E., Nevolo, M., Lehmann, K., Downward, J., Beug, H., Grieco, M. (2006) Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene. 25(54):7117-30

Jechlinger, M., Sommer, A., Moriggl, R., Seither, P., Kraut, N., Capodiecci, P., Donovan, M., Cordon-Cardo, C., Beug, H., Grünert, S. (2006) Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest. 116(6):1561-70

Jenuwein T., Almouzni G., Avner P. (2006) Epigenom BIOFUTUR . (268):67-69

Jenuwein, T. (2006) The epigenetic magic of histone lysine methylation. FEBS J. 273(14):3121-35

Jones, DH., Nakashima, T., Sanchez, OH., Kozieradzki, I., Komarova, SV., Sarosi, I., Morony, S., Rubin, E., Sarao, R., Hojilla, CV., Komnenovic, V., Kong, YY., Schreiber, M., Dixon, SJ., Sims, SM., Khokha, R., Wada, T., Penninger, JM. (2006) Regulation of cancer cell migration and bone metastasis by RANKL. Nature. 440(7084):692-6

Kovacic, B., Stoiber, D., Moriggl, R., Weisz, E., Ott, RG., Kreibich, R., Levy, DE., Beug, H., Freissmuth, M., Sexl, V. (2006) STAT1 acts as a tumor promoter for leukemia development. Cancer Cell. 10(1):77-87

Kraft, C., Gmachl, M., Peters, JM. (2006) Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex. Methods. 38(1):39-51

Kubicek, S., Schotta, G., Lachner, M., Sengupta, R., Kohlmaier, A., Perez-Burgos, L., Linderson, Y., Martens, JH., O'Sullivan, RJ., Fodor, BD., Yonezawa, M., Peters, AH., Jenuwein, T. (2006) The role of histone modifications in epigenetic transitions during normal and perturbed development. Ernst Schering Res Found Workshop. (57):1-27

Kudo, NR., Wassmann, K., Anger, M., Schuh, M., Wirth, KG., Xu, H., Helmhart, W., Kudo, H., McKay, M., Maro, B., Ellenberg, J., de Boer, P., Nasmyth, K. (2006) Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Cell. 126(1):135-46

Kueng, S., Hegemann, B., Peters, BH., Lipp, JJ., Schleiffer, A., Mechtler, K., Peters, JM. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell. 127(5):955-67

Kvitsiani, D., Dickson, BJ. (2006) Shared neural circuitry for female and male sexual behaviours in Drosophila. Curr Biol. 16(10):R355-6

Kyewski, B., Klein, L. (2006) A central role for central tolerance. Annu Rev Immunol. 24:571-606

Lénárt, P., Peters, JM. (2006) Checkpoint activation: don't get mad too much. Curr Biol. 16(11):R412-4

Leuschner, PJ., Ameres, SL., Kueng, S., Martinez, J. (2006) Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep. 7(3):314-20

McGarvey, KM., Fahrner, JA., Greene, E., Martens, J., Jenuwein, T., Baylin, SB. (2006) Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res. 66(7):3541-9

Mitulovic, G., Mechtler, K. (2006) HPLC techniques for proteomics analysis--a short overview of latest developments. Brief Funct Genomic Proteomic. 5(4):249-60

Morandell, S., Stasyk, T., Grosstessner-Hain, K., Roitinger, E., Mechtler, K., Bonn, GK., Huber, LA. (2006) Phosphoproteomics strategies for the functional analysis of signal transduction. Proteomics. 6(14):4047-56

Mujezinovic, N., Raidl, G., Hutchins, JR., Peters, JM., Mechtler, K., Eisenhaber, F. (2006) Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise. Proteomics. 6(19):5117-31

Novatchkova, M., Schneider, G., Fritz, R., Eisenhaber, F., Schleiffer, A. (2006) DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity. Nucleic Acids Res. 34(Web Server issue):W214-8

Obernosterer, G., Leuschner, PJ., Alenius, M., Martinez, J. (2006) Post-transcriptional regulation of microRNA expression. RNA. 12(7):1161-7

Peters, JM. (2006) The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol. 7(9):644-56

Petronczki, M., Matos, J., Mori, S., Gregan, J., Bogdanova, A., Schwickart, M., Mechtler, K., Shirahige, K., Zachariae, W., Nasmyth, K. (2006) Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Cell. 126(6):1049-64

Rangachari, M., Mauermann, N., Marty, RR., Dirnhofer, S., Kurrer, MO., Komnenovic, V., Penninger, JM., Eriksson, U. (2006) T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med. 203(8):2009-19

Resch, GP., Small, JV., Goldie, KN. (2006) Electron Microscopy of Extracted Cytoskeletons: Negative Staining, Cryoelectron Microscopy and Correlation with Light Microscopy. Cell Biology - A Laboratory Handbook (J. E. Celis, ed.).

Riedel, CG., Katis, VL., Katou, Y., Mori, S., Itoh, T., Helmhart, W., Gálová, M., Petronczki, M., Gregan, J., Cetin, B., Mudrak, I., Ogris, E., Mechtler, K., Pelletier, L., Buchholz, F., Shirahige, K., Nasmyth, K. (2006) Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I. Nature. 441(7089):53-61

Rubiolo, C., Piazzolla, D., Meissl, K., Beug, H., Huber, JC., Kolbus, A., Baccarini, M. (2006) A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation. Blood. 108(1):152-9

Savarese, F., Flahndorfer, K., Jaenisch, R., Busslinger, M., Wutz, A. (2006) Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation. Mol Cell Biol. 26(19):7167-77

Schneider, G., Neuberger, G., Wildpaner, M., Tian, S., Berezovsky, I., Eisenhaber, F. (2006) Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases. BMC Bioinformatics. 7:164

Schoeftner, S., Sengupta, AK., Kubicek, S., Mechtler, K., Spahn, L., Koseki, H., Jenuwein, T., Wutz, A. (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J. 25(13):3110-22

Schranzhofer, M., Schifrer, M., Cabrera, JA., Kopp, S., Chiba, P., Beug, H., Müllner, EW. (2006) Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood. 107(10):4159-67

Schubert, D., Primavesi, L., Bishopp, A., Roberts, G., Doonan, J., Jenuwein, T., Goodrich, J. (2006) Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27. EMBO J. 25(19):4638-49

Shumaker, DK., Dechat, T., Kohlmaier, A., Adam, SA., Bozovsky, MR., Erdos, MR., Eriksson, M., Goldman, AE., Khuon, S., Collins, FS., Jenuwein, T., Goldman, RD. (2006) Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci U S A. 103(23):8703-8

Sobkow, L., Epperlein, HH., Herklotz, S., Straube, WL., Tanaka, EM. (2006) A germline GFP transgenic axolotl and its use to track cell fate: dual origin of the fin mesenchyme during development and the fate of blood cells during regeneration. Dev Biol. 290(2):386-97

Später, D., Hill, TP., Gruber, M., Hartmann, C. (2006) Role of canonical Wnt-signalling in joint formation. Eur Cell Mater. 12:71-80

Später, D., Hill, TP., O'sullivan, RJ., Gruber, M., Conner, DA., Hartmann, C. (2006) Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis. Development. 133(15):3039-49

Steffen, A., Faix, J., Resch, GP., Linkner, J., Wehland, J., Small, JV., Rottner, K., Stradal, TE. (2006) Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes. Mol Biol Cell. 17(6):2581-91

Stepniak, E., Ricci, R., Eferl, R., Sumara, G., Sumara, I., Rath, M., Hui, L., Wagner, EF. (2006) c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity. Genes Dev. 20(16):2306-14

Stingl, C., Ihling, C., Ammerer, G., Sinz, A., Mechtler, K. (2006) Application of different fragmentation techniques for the analysis of phosphopeptides using a hybrid linear ion trap-FTICR mass spectrometer. Biochim Biophys Acta. 1764(12):1842-52

Straube, WL., Tanaka, EM. (2006) Reversibility of the differentiated state: regeneration in amphibians. Artif Organs. 30(10):743-55

Tagoh, H., Ingram, R., Wilson, N., Salvagiotto, G., Warren, AJ., Clarke, D., Busslinger, M., Bonifer, C. (2006) The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction. EMBO J. 25(5):1070-80

Teis, D., Taub, N., Kurzbauer, R., Hilber, D., de Araujo, ME., Erlacher, M., Offterdinger, M., Villunger, A., Geley, S., Bohn, G., Klein, C., Hess, MW., Huber, LA. (2006) p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis. J Cell Biol. 175(6):861-8

Vishnu, S., Hertenstein, A., Betschinger, J., Knoblich, JA., Gert de Couet, H., Fischbach, KF. (2006) The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila. Dev Biol. 289(2):296-307

Vrontou, E., Nilsen, SP., Demir, E., Kravitz, EA., Dickson, BJ. (2006) fruitless regulates aggression and dominance in Drosophila. Nat Neurosci. 9(12):1469-71

Waerner, T., Alacakaptan, M., Tamir, I., Oberauer, R., Gal, A., Brabletz, T., Schreiber, M., Jechlinger, M., Beug, H. (2006) ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell. 10(3):227-39

Wagner, B., Natarajan, A., Grünaug, S., Kroismayr, R., Wagner, EF., Sibilia, M. (2006) Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes. EMBO J. 25(4):752-62

Watrin, E., Peters, JM. (2006) Cohesin and DNA damage repair. Exp Cell Res. 312(14):2687-93

Watrin, E., Schleiffer, A., Tanaka, K., Eisenhaber, F., Nasmyth, K., Peters, JM. (2006) Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression. Curr Biol. 16(9):863-74

Weisheit, G., Gliem, M., Endl, E., Pfeffer, PL., Busslinger, M., Schilling, K. (2006) Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons. Eur J Neurosci. 24(2):466-78

Wirth, KG., Wutz, G., Kudo, NR., Desdouets, C., Zetterberg, A., Taghybeeglu, S., Seznec, J., Ducos, GM., Ricci, R., Firnberg, N., Peters, JM., Nasmyth, K. (2006) Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression. J Cell Biol. 172(6):847-60

Yu, JY., Dickson, BJ. (2006) Sexual behaviour: do a few dead neurons make the difference? Curr Biol. 16(1):R23-5

Zenz, R., Wagner, EF. (2006) Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors. Int J Biochem Cell Biol. 38(7):1043-9

2005

Ameyar-Zazoua, M., Wisniewska, MB., Bakiri, L., Wagner, EF., Yaniv, M., Weitzman, JB. (2005) AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene. Oncogene. 24(14):2298-306

Angelin-Duclos, C., Domenget, C., Kolbus, A., Beug, H., Jurdic, P., Samarut, J. (2005) Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development. 132(5):925-34

Ardouin, L., Rolink, AG., Mura, AM., Gommeaux, J., Melchers, F., Busslinger, M., Malissen, M., Malissen, B. (2005) Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells. Eur J Immunol. 35(3):977-86

Asagiri, M., Sato, K., Usami, T., Ochi, S., Nishina, H., Yoshida, H., Morita, I., Wagner, EF., Mak, TW., Serfling, E., Takayanagi, H. (2005) Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med. 202(9):1261-9

Bao, S., Miyoshi, N., Okamoto, I., Jenuwein, T., Heard, E., Azim Surani, M. (2005) Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte. EMBO Rep. 6(8):748-54

Besirli, CG., Wagner, EF., Johnson, EM. (2005) The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway. J Cell Biol. 170(3):401-11

Betschinger, J., Eisenhaber, F., Knoblich, JA. (2005) Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. Curr Biol. 15(3):276-82

Bhalerao, S., Berdnik, D., Török, T., Knoblich, JA. (2005) Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila. Curr Biol. 15(17):1583-90

Bos, R., van Duikeren, S., van Hall, T., Kaaijk, P., Taubert, R., Kyewski, B., Klein, L., Melief, CJ., Offringa, R. (2005) Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire. Cancer Res. 65(14):6443-9

Bouchard, M., Grote, D., Craven, SE., Sun, Q., Steinlein, P., Busslinger, M. (2005) Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region. Development. 132(11):2633-43

Braig, M., Lee, S., Loddenkemper, C., Rudolph, C., Peters, AH., Schlegelberger, B., Stein, H., Dörken, B., Jenuwein, T., Schmitt, CA. (2005) Oncogene-induced senescence as an initial barrier in lymphoma development. Nature. 436(7051):660-5

Brecht, S., Kirchhof, R., Chromik, A., Willesen, M., Nicolaus, T., Raivich, G., Wessig, J., Waetzig, V., Goetz, M., Claussen, M., Pearse, D., Kuan, CY., Vaudano, E., Behrens, A., Wagner, E., Flavell, RA., Davis, RJ., Herdegen, T. (2005) Specific pathophysiological functions of JNK isoforms in the brain. Eur J Neurosci. 21(2):363-77

Corvinus, FM., Orth, C., Moriggl, R., Tsareva, SA., Wagner, S., Pfitzner, EB., Baus, D., Kaufmann, R., Huber, LA., Zatloukal, K., Beug, H., Ohlschläger, P., Schütz, A., Halbhuber, KJ., Friedrich, K. (2005) Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia. 7(6):545-55

D'Cruz, LM., Klein, L. (2005) Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat Immunol. 6(11):1152-9

da Silva, AV., Pezerico, SB., de Lima, VY., d'Arc Moretti, L., Pinheiro, JP., Tanaka, EM., Ribeiro, MG., Langoni, H. (2005) Genotyping of Toxoplasma gondii strains isolated from dogs with neurological signs. Vet Parasitol. 127(1):23-7

David, JP., Mehic, D., Bakiri, L., Schilling, AF., Mandic, V., Priemel, M., Idarraga, MH., Reschke, MO., Hoffmann, O., Amling, M., Wagner, EF. (2005) Essential role of RSK2 in c-Fos-dependent osteosarcoma development. J Clin Invest. 115(3):664-72

Dolznig, H., Kolbus, A., Leberbauer, C., Schmidt, U., Deiner, EM., Müllner, EW., Beug, H. (2005) Expansion and differentiation of immature mouse and human hematopoietic progenitors. Methods Mol Med. 105:323-44

Drissen, R., von Lindern, M., Kolbus, A., Driegen, S., Steinlein, P., Beug, H., Grosveld, F., Philipsen, S. (2005) The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol. 25(12):5205-14

Dube, P., Herzog, F., Gieffers, C., Sander, B., Riedel, D., Müller, SA., Engel, A., Peters, JM., Stark, H. (2005) Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Mol Cell. 20(6):867-79

Echeverri, K., Tanaka, EM. (2005) Proximodistal patterning during limb regeneration. Dev Biol. 279(2):391-401

Eger, A., Aigner, K., Sonderegger, S., Dampier, B., Oehler, S., Schreiber, M., Berx, G., Cano, A., Beug, H., Foisner, R. (2005) DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene. 24(14):2375-85

Eisenhaber F. (2005) Bioinformatics: Mystery, Astrology or Service Technology. Preface for "Discovering Biomolecular Mechanisms with Computational Biology" Georgetown: Landes Biosciences and Eurekah.com. :1-10

Eisenhaber F. (2005) Discovering Biomolecular Mechanisms with Computational Biology. Georgetown: Landes Biosciences and Eurekah.com.

Eisenhaber F. (2005) Prediction of the Protein Function: Two Basic Concepts and One Practical Recipe. Chapter 3 in Georgetown: Landes Biosciences and Eurekah.com. :38-53

Eisenhaber, B., Eisenhaber, F. (2005) Sequence complexity of proteins and its significance in annotation. "Bioinformatics" in the Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics (Subramaniam, S., ed.).

Emery, G., Hutterer, A., Berdnik, D., Mayer, B., Wirtz-Peitz, F., Gaitan, MG., Knoblich, JA. (2005) Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system. Cell. 122(5):763-73

Fischer, AN., Herrera, B., Mikula, M., Proell, V., Fuchs, E., Gotzmann, J., Schulte-Hermann, R., Beug, H., Mikulits, W. (2005) Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis. Carcinogenesis. 26(5):931-42

Fraga, MF., Ballestar, E., Villar-Garea, A., Boix-Chornet, M., Espada, J., Schotta, G., Bonaldi, T., Haydon, C., Ropero, S., Petrie, K., Iyer, NG., Pérez-Rosado, A., Calvo, E., Lopez, JA., Cano, A., Calasanz, MJ., Colomer, D., Piris, MA., Ahn, N., Imhof, A., Caldas, C., Jenuwein, T., Esteller, M. (2005) Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat Genet. 37(4):391-400

Fu, L., Patel, MS., Bradley, A., Wagner, EF., Karsenty, G. (2005) The molecular clock mediates leptin-regulated bone formation. Cell. 122(5):803-15

Gillardon, F., Steinlein, P., Bürger, E., Hildebrandt, T., Gerner, C. (2005) Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor. Proteomics. 5(5):1299-307

Giménez-Abián, JF., Díaz-Martínez, LA., Waizenegger, IC., Giménez-Martín, G., Clarke, DJ. (2005) Separase is required at multiple pre-anaphase cell cycle stages in human cells. Cell Cycle. 4(11):1576-84

Glotzer, M. (2005) The molecular requirements for cytokinesis. Science. 307(5716):1735-9

Gonzalo, S., García-Cao, M., Fraga, MF., Schotta, G., Peters, AH., Cotter, SE., Eguía, R., Dean, DC., Esteller, M., Jenuwein, T., Blasco, MA. (2005) Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol. 7(4):420-8

Grau, S., Baldi, A., Bussani, R., Tian, X., Stefanescu, R., Przybylski, M., Richards, P., Jones, SA., Shridhar, V., Clausen, T., Ehrmann, M. (2005) Implications of the serine protease HtrA1 in amyloid precursor protein processing. Proc Natl Acad Sci U S A. 102(17):6021-6

Grebien, F., Dolznig, H., Beug, H., Mullner, EW. (2005) Cell size control: new evidence for a general mechanism. Cell Cycle. 4(3):418-21

Gregan, J. (2005) Conditional alleles, inteins and degrons. Nat Biotechnol. 23(1):18

Gregan, J., Rabitsch, PK., Sakem, B., Csutak, O., Latypov, V., Lehmann, E., Kohli, J., Nasmyth, K. (2005) Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast. Curr Biol. 15(18):1663-9

Grillari, J., Ajuh, P., Stadler, G., Löscher, M., Voglauer, R., Ernst, W., Chusainow, J., Eisenhaber, F., Pokar, M., Fortschegger, K., Grey, M., Lamond, AI., Katinger, H. (2005) SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly. Nucleic Acids Res. 33(21):6868-83

Groll, M., Bochtler, M., Brandstetter, H., Clausen, T., Huber, R. (2005) Molecular machines for protein degradation. Chembiochem. 6(2):222-56

Guse, A., Mishima, M., Glotzer, M. (2005) Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis. Curr Biol. 15(8):778-86

Hackl, H., Burkard, TR., Sturn, A., Rubio, R., Schleiffer, A., Tian, S., Quackenbush, J., Eisenhaber, F., Trajanoski, Z. (2005) Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome Biol. 6(13):R108

Hamant, O., Golubovskaya, I., Meeley, R., Fiume, E., Timofejeva, L., Schleiffer, A., Nasmyth, K., Cande, WZ. (2005) A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions. Curr Biol. 15(10):948-54

Hasselblatt, P., Hockenjos, B., Thoma, C., Blum, HE., Offensperger, WB. (2005) Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides. Nucleic Acids Res. 33(1):114-25

Hauf, S., Roitinger, E., Koch, B., Dittrich, CM., Mechtler, K., Peters, JM. (2005) Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2. PLoS Biol. 3(3):e69

Hayer, S., Steiner, G., Görtz, B., Reiter, E., Tohidast-Akrad, M., Amling, M., Hoffmann, O., Redlich, K., Zwerina, J., Skriner, K., Hilberg, F., Wagner, EF., Smolen, JS., Schett, G. (2005) CD44 is a determinant of inflammatory bone loss. J Exp Med. 201(6):903-14

Herzog, F., Mechtler, K., Peters, JM. (2005) Identification of cell cycle-dependent phosphorylation sites on the anaphase-promoting complex/cyclosome by mass spectrometry. Methods Enzymol. 398:231-45

Herzog, F., Peters, JM. (2005) Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome. Methods Enzymol. 398:175-95

Hill, TP., Später, D., Taketo, MM., Birchmeier, W., Hartmann, C. (2005) Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes. Dev Cell. 8(5):727-38

Hirota, T., Lipp, JJ., Toh, BH., Peters, JM. (2005) Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin. Nature. 438(7071):1176-80

Huber, MA., Kraut, N., Beug, H. (2005) Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol. 17(5):548-58

Ivanov, D., Nasmyth, K. (2005) A topological interaction between cohesin rings and a circular minichromosome. Cell. 122(6):849-60

Jerkovic, L., Voegele, AF., Chwatal, S., Kronenberg, F., Radcliffe, CM., Wormald, MR., Lobentanz, EM., Ezeh, B., Eller, P., Dejori, N., Dieplinger, B., Lottspeich, F., Sattler, W., Uhr, M., Mechtler, K., Dwek, RA., Rudd, PM., Baier, G., Dieplinger, H. (2005) Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. J Proteome Res. 4(3):889-99

Kalkhof, S., Ihling, C., Mechtler, K., Sinz, A. (2005) Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex. Anal Chem. 77(2):495-503

Kanellopoulou, C., Muljo, SA., Kung, AL., Ganesan, S., Drapkin, R., Jenuwein, T., Livingston, DM., Rajewsky, K. (2005) Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19(4):489-501

Kinoshita, K., Noetzel, TL., Pelletier, L., Mechtler, K., Drechsel, DN., Schwager, A., Lee, M., Raff, JW., Hyman, AA. (2005) Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis. J Cell Biol. 170(7):1047-55

Kitzing, K., Fitzpatrick, TB., Wilken, C., Sawa, J., Bourenkov, GP., Macheroux, P., Clausen, T. (2005) The 1.3 A crystal structure of the flavoprotein YqjM reveals a novel class of Old Yellow Enzymes. J Biol Chem. 280(30):27904-13

Klein, L., Emmerich, J., d'Cruz, L., Aschenbrenner, K., Khazaie, K. (2005) Selection and behavior of CD4+ CD25+ T cells in vivo: lessons from T cell receptor transgenic models. Curr Top Microbiol Immunol. 293:73-87

Köller, M., Hayer, S., Redlich, K., Ricci, R., David, JP., Steiner, G., Smolen, JS., Wagner, EF., Schett, G. (2005) JNK1 is not essential for TNF-mediated joint disease. Arthritis Res Ther. 7(1):R166-73

Koyanagi, M., Baguet, A., Martens, J., Margueron, R., Jenuwein, T., Bix, M. (2005) EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells. J Biol Chem. 280(36):31470-7

Kraft, C., Vodermaier, HC., Maurer-Stroh, S., Eisenhaber, F., Peters, JM. (2005) The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates. Mol Cell. 18(5):543-53

Leberbauer, C., Boulmé, F., Unfried, G., Huber, J., Beug, H., Müllner, EW. (2005) Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors. Blood. 105(1):85-94

Leksa, V., Godar, S., Schiller, HB., Fuertbauer, E., Muhammad, A., Slezakova, K., Horejsi, V., Steinlein, P., Weidle, UH., Binder, BR., Stockinger, H. (2005) TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen. J Cell Sci. 118(Pt 19):4577-86

Martens, JH., O'Sullivan, RJ., Braunschweig, U., Opravil, S., Radolf, M., Steinlein, P., Jenuwein, T. (2005) The profile of repeat-associated histone lysine methylation states in the mouse epigenome. EMBO J. 24(4):800-12

Maschler, S., Wirl, G., Spring, H., Bredow, DV., Sordat, I., Beug, H., Reichmann, E. (2005) Tumor cell invasiveness correlates with changes in integrin expression and localization. Oncogene. 24(12):2032-41

Maurer-Stroh, S., Eisenhaber, F. (2005) Refinement and prediction of protein prenylation motifs. Genome Biol. 6(6):R55

McGuinness, BE., Hirota, T., Kudo, NR., Peters, JM., Nasmyth, K. (2005) Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells. PLoS Biol. 3(3):e86

Mehic, D., Bakiri, L., Ghannadan, M., Wagner, EF., Tschachler, E. (2005) Fos and jun proteins are specifically expressed during differentiation of human keratinocytes. J Invest Dermatol. 124(1):212-20

Mercader, N., Tanaka, EM., Torres, M. (2005) Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins. Development. 132(18):4131-42

Moriggl, R., Sexl, V., Kenner, L., Duntsch, C., Stangl, K., Gingras, S., Hoffmeyer, A., Bauer, A., Piekorz, R., Wang, D., Bunting, KD., Wagner, EF., Sonneck, K., Valent, P., Ihle, JN., Beug, H. (2005) Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell. 7(1):87-99

Nasmyth, K. (2005) How do so few control so many? Cell. 120(6):739-46

Nasmyth, K. (2005) How might cohesin hold sister chromatids together? Philos Trans R Soc Lond B Biol Sci. 360(1455):483-96

Nasmyth, K., Haering, CH. (2005) The structure and function of SMC and kleisin complexes. Annu Rev Biochem. 74:595-648

Naumann, K., Fischer, A., Hofmann, I., Krauss, V., Phalke, S., Irmler, K., Hause, G., Aurich, AC., Dorn, R., Jenuwein, T., Reuter, G. (2005) Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis. EMBO J. 24(7):1418-29

Novatchkova, M., Bachmair, A., Eisenhaber, B., Eisenhaber, F. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics. 6:22

Novatchkova, M., Wildpaner, M., Schweizer, D., Eisenhaber, F. (2005) PhyloDome--visualization of taxonomic distributions of domains occurring in eukaryote protein sequence sets. Nucleic Acids Res. 33(Web Server issue):W121-5

O'Connor, E., Eisenhaber, B., Dalley, J., Wang, T., Missen, C., Bulleid, N., Bishop, PN., Trump, D. (2005) Species specific membrane anchoring of nyctalopin, a small leucine-rich repeat protein. Hum Mol Genet. 14(13):1877-87

Pelayo, R., Hirose, J., Huang, J., Garrett, KP., Delogu, A., Busslinger, M., Kincade, PW. (2005) Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow. Blood. 105(11):4407-15

Peters, JM. (2005) Cyclin degradation: don't mes(s) with meiosis. Curr Biol. 15(12):R461-3

Pilat, S., Carotta, S., Schiedlmeier, B., Kamino, K., Mairhofer, A., Will, E., Modlich, U., Steinlein, P., Ostertag, W., Baum, C., Beug, H., Klump, H. (2005) HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A. 102(34):12101-6

Ricci, R., Eriksson, U., Oudit, GY., Eferl, R., Akhmedov, A., Sumara, I., Sumara, G., Kassiri, Z., David, JP., Bakiri, L., Sasse, B., Idarraga, MH., Rath, M., Kurz, D., Theussl, HC., Perriard, JC., Backx, P., Penninger, JM., Wagner, EF. (2005) Distinct functions of junD in cardiac hypertrophy and heart failure. Genes Dev. 19(2):208-13

Roldán, E., Fuxa, M., Chong, W., Martinez, D., Novatchkova, M., Busslinger, M., Skok, JA. (2005) Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene. Nat Immunol. 6(1):31-41

Ruocco, MG., Maeda, S., Park, JM., Lawrence, T., Hsu, LC., Cao, Y., Schett, G., Wagner, EF., Karin, M. (2005) I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss. J Exp Med. 201(10):1677-87

Schnapp, E., Kragl, M., Rubin, L., Tanaka, EM. (2005) Hedgehog signaling controls dorsoventral patterning, blastema cell proliferation and cartilage induction during axolotl tail regeneration. Development. 132(14):3243-53

Schnapp, E., Tanaka, EM., Tamaka, EM. (2005) Quantitative evaluation of morpholino-mediated protein knockdown of GFP, MSX1, and PAX7 during tail regeneration in Ambystoma mexicanum. Dev Dyn. 232(1):162-70

Terme, M., Borg, C., Guilhot, F., Masurier, C., Flament, C., Wagner, EF., Caillat-Zucman, S., Bernheim, A., Turhan, AG., Caignard, A., Zitvogel, L. (2005) BCR/ABL promotes dendritic cell-mediated natural killer cell activation. Cancer Res. 65(14):6409-17

Vaur, S., Cubizolles, F., Plane, G., Genier, S., Rabitsch, PK., Gregan, J., Nasmyth, K., Vanoosthuyse, V., Hardwick, KG., Javerzat, JP. (2005) Control of Shugoshin function during fission-yeast meiosis. Curr Biol. 15(24):2263-70

Vietor, I., Kurzbauer, R., Brosch, G., Huber, LA. (2005) TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent. J Biol Chem. 280(48):39795-801

Wagner, EF., Eferl, R. (2005) Fos/AP-1 proteins in bone and the immune system. Immunol Rev. 208:126-40

Yanagida, M., Nasmyth, K. (2005) Introduction: dissection and simplification of chromosome segregation. Philos Trans R Soc Lond B Biol Sci. 360(1455):481

Yüce, O., Piekny, A., Glotzer, M. (2005) An ECT2-centralspindlin complex regulates the localization and function of RhoA. J Cell Biol. 170(4):571-82

Zarnescu, DC., Jin, P., Betschinger, J., Nakamoto, M., Wang, Y., Dockendorff, TC., Feng, Y., Jongens, TA., Sisson, JC., Knoblich, JA., Warren, ST., Moses, K. (2005) Fragile X protein functions with lgl and the par complex in flies and mice. Dev Cell. 8(1):43-52

Zenz, R., Eferl, R., Kenner, L., Florin, L., Hummerich, L., Mehic, D., Scheuch, H., Angel, P., Tschachler, E., Wagner, EF. (2005) Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. Nature. 437(7057):369-75

Zigman, M., Cayouette, M., Charalambous, C., Schleiffer, A., Hoeller, O., Dunican, D., McCudden, CR., Firnberg, N., Barres, BA., Siderovski, DP., Knoblich, JA. (2005) Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina. Neuron. 48(4):539-45

2004

Acquaviva, C., Herzog, F., Kraft, C., Pines, J. (2004) The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint. Nat Cell Biol. 6(9):892-8

Amatschek, S., Koenig, U., Auer, H., Steinlein, P., Pacher, M., Gruenfelder, A., Dekan, G., Vogl, S., Kubista, E., Heider, KH., Stratowa, C., Schreiber, M., Sommergruber, W. (2004) Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes. Cancer Res. 64(3):844-56

Azzam, R., Chen, SL., Shou, W., Mah, AS., Alexandru, G., Nasmyth, K., Annan, RS., Carr, SA., Deshaies, RJ. (2004) Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus. Science. 305(5683):516-9

Bakker, WJ., Blázquez-Domingo, M., Kolbus, A., Besooyen, J., Steinlein, P., Beug, H., Coffer, PJ., Löwenberg, B., von Lindern, M., van Dijk, TB. (2004) FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol. 164(2):175-84

Balasubramanian, MK., Bi, E., Glotzer, M. (2004) Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells. Curr Biol. 14(18):R806-18

Baxter, J., Sauer, S., Peters, A., John, R., Williams, R., Caparros, ML., Arney, K., Otte, A., Jenuwein, T., Merkenschlager, M., Fisher, AG. (2004) Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes. EMBO J. 23(22):4462-72

Betschinger, J., Knoblich, JA. (2004) Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates. Curr Biol. 14(16):R674-85

Beyer A., Lawtrakul L., Hannongbua S., Wolschann P. (2004) Systematic Investigation of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase (NNRTIs) Chemical Monthly . 135(8):1047-1059

Bouchard, M., Souabni, A., Busslinger, M. (2004) Tissue-specific expression of cre recombinase from the Pax8 locus. Genesis. 38(3):105-9

Bourbon, HM., Aguilera, A., Ansari, AZ., Asturias, FJ., Berk, AJ., Bjorklund, S., Blackwell, TK., Borggrefe, T., Carey, M., Carlson, M., Conaway, JW., Conaway, RC., Emmons, SW., Fondell, JD., Freedman, LP., Fukasawa, T., Gustafsson, CM., Han, M., He, X., Herman, PK., Hinnebusch, AG., Holmberg, S., Holstege, FC., Jaehning, JA., Kim, YJ., Kuras, L., Leutz, A., Lis, JT., Meisterernest, M., Naar, AM., Nasmyth, K., Parvin, JD., Ptashne, M., Reinberg, D., Ronne, H., Sadowski, I., Sakurai, H., Sipiczki, M., Sternberg, PW., Stillman, DJ., Strich, R., Struhl, K., Svejstrup, JQ., Tuck, S., Winston, F., Roeder, RG., Kornberg, RD. (2004) A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell. 14(5):553-7

Busslinger, M. (2004) Transcriptional control of early B cell development. Annu Rev Immunol. 22:55-79

Carotta, S., Pilat, S., Mairhofer, A., Schmidt, U., Dolznig, H., Steinlein, P., Beug, H. (2004) Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood. 104(6):1873-80

Cheng, L., Arata, A., Mizuguchi, R., Qian, Y., Karunaratne, A., Gray, PA., Arata, S., Shirasawa, S., Bouchard, M., Luo, P., Chen, CL., Busslinger, M., Goulding, M., Onimaru, H., Ma, Q. (2004) Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 7(5):510-7

Cserzo, M., Eisenhaber, F., Eisenhaber, B., Simon, I. (2004) TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter. Bioinformatics. 20(1):136-7

Dewar, H., Tanaka, K., Nasmyth, K., Tanaka, TU. (2004) Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle. Nature. 428(6978):93-7

Dolznig, H., Grebien, F., Sauer, T., Beug, H., Müllner, EW. (2004) Evidence for a size-sensing mechanism in animal cells. Nat Cell Biol. 6(9):899-905

Ebert, A., Schotta, G., Lein, S., Kubicek, S., Krauss, V., Jenuwein, T., Reuter, G. (2004) Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev. 18(23):2973-83

Eferl, R., Hoebertz, A., Schilling, AF., Rath, M., Karreth, F., Kenner, L., Amling, M., Wagner, EF. (2004) The Fos-related antigen Fra-1 is an activator of bone matrix formation. EMBO J. 23(14):2789-99

Eger, A., Stockinger, A., Park, J., Langkopf, E., Mikula, M., Gotzmann, J., Mikulits, W., Beug, H., Foisner, R. (2004) beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene. 23(15):2672-2680

Ehrmann, M., Clausen, T. (2004) Proteolysis as a regulatory mechanism. Annu Rev Genet. 38:709-24

Eisenhaber, B., Eisenhaber, F., Maurer-Stroh, S., Neuberger, G. (2004) Prediction of sequence signals for lipid post-translational modifications: insights from case studies. Proteomics. 4(6):1614-25

Eisenhaber, B., Schneider, G., Wildpaner, M., Eisenhaber, F. (2004) A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces pombe. J Mol Biol. 337(2):243-53

Fitzpatrick, TB., Auweter, S., Kitzing, K., Clausen, T., Amrhein, N., Macheroux, P. (2004) Structural and functional impairment of an Old Yellow Enzyme homologue upon affinity tag incorporation. Protein Expr Purif. 36(2):280-91

Fuxa, M., Skok, J., Souabni, A., Salvagiotto, G., Roldan, E., Busslinger, M. (2004) Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene. Genes Dev. 18(4):411-22

García-Cao, M., O'Sullivan, R., Peters, AH., Jenuwein, T., Blasco, MA. (2004) Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet. 36(1):94-9

Gass, P., Fleischmann, A., Hvalby, O., Jensen, V., Zacher, C., Strekalova, T., Kvello, A., Wagner, EF., Sprengel, R. (2004) Mice with a fra-1 knock-in into the c-fos locus show impaired spatial but regular contextual learning and normal LTP. Brain Res Mol Brain Res. 130(1-2):16-22

Giménez-Abián, JF., Sumara, I., Hirota, T., Hauf, S., Gerlich, D., de la Torre, C., Ellenberg, J., Peters, JM. (2004) Regulation of sister chromatid cohesion between chromosome arms. Curr Biol. 14(13):1187-93

Glotzer, M. (2004) Cleavage furrow positioning. J Cell Biol. 164(3):347-51

Görtz, B., Hayer, S., Redlich, K., Zwerina, J., Tohidast-Akrad, M., Tuerk, B., Hartmann, C., Kollias, G., Steiner, G., Smolen, JS., Schett, G. (2004) Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation. J Bone Miner Res. 19(6):990-8

Gotzmann, J., Mikula, M., Eger, A., Schulte-Hermann, R., Foisner, R., Beug, H., Mikulits, W. (2004) Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res. 566(1):9-20

Habermann, B., Bebin, AG., Herklotz, S., Volkmer, M., Eckelt, K., Pehlke, K., Epperlein, HH., Schackert, HK., Wiebe, G., Tanaka, EM. (2004) An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and regenerating blastema cDNA libraries. Genome Biol. 5(9):R67

Haering, CH., Schoffnegger, D., Nishino, T., Helmhart, W., Nasmyth, K., Löwe, J. (2004) Structure and stability of cohesin's Smc1-kleisin interaction. Mol Cell. 15(6):951-64

Haigh, JJ., Ema, M., Haigh, K., Gertsenstein, M., Greer, P., Rossant, J., Nagy, A., Wagner, EF. (2004) Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells. Blood. 103(3):912-20

Heidmann, D., Horn, S., Heidmann, S., Schleiffer, A., Nasmyth, K., Lehner, CF. (2004) The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions. Chromosoma. 113(4):177-87

Higgins, DF., Biju, MP., Akai, Y., Wutz, A., Johnson, RS., Haase, VH. (2004) Hypoxic induction of Ctgf is directly mediated by Hif-1. Am J Physiol Renal Physiol. 287(6):F1223-32

Hirota, T. (2004) [Setting the stage for mitosis: kinase regulation of prophase]. Tanpakushitsu Kakusan Koso. 49(8):1183-94

Hirota, T., Gerlich, D., Koch, B., Ellenberg, J., Peters, JM. (2004) Distinct functions of condensin I and II in mitotic chromosome assembly. J Cell Sci. 117(Pt 26):6435-45

Höflinger, S., Kesavan, K., Fuxa, M., Hutter, C., Heavey, B., Radtke, F., Busslinger, M. (2004) Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors. J Immunol. 173(6):3935-44

Huber, MA., Azoitei, N., Baumann, B., Grünert, S., Sommer, A., Pehamberger, H., Kraut, N., Beug, H., Wirth, T. (2004) NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest. 114(4):569-81