Publications | IMP Scientific Papers | Research Institute of Molecular Pathology (IMP)

The IMP publishes 60 to 90 scientific papers in international peer-review journals every year. This evidence for the productivity and high scientific standard of the IMP is listed here in full – a directory of all scientific publications by IMP scientists since the establishment of the institute, organised by years and research groups.

2018

Adams, FF., Hoffmann, T., Zuber, J., Heckl, D., Schambach, A., Schwarzer, A. (2018) Pooled Generation of Lentiviral Tetracycline-Regulated microRNA Embedded Short Hairpin RNA Libraries. Hum Gene Ther Methods. 29(1):16-29

Alberti, C., Manzenreither, RA., Sowemimo, I., Burkard, TR., Wang, J., Mahofsky, K., Ameres, SL., Cochella, L. (2018) Cell-type specific sequencing of microRNAs from complex animal tissues. Nat Methods. 15(4):283-289

Arnold, CD., Nemčko, F., Woodfin, AR., Wienerroither, S., Vlasova, A., Schleiffer, A., Pagani, M., Rath, M., Stark, A. (2018) A high-throughput method to identify trans-activation domains within transcription factor sequences. EMBO J.

Ayata, P., Badimon, A., Strasburger, HJ., Duff, MK., Montgomery, SE., Loh, YE., Ebert, A., Pimenova, AA., Ramirez, BR., Chan, AT., Sullivan, JM., Purushothaman, I., Scarpa, JR., Goate, AM., Busslinger, M., Shen, L., Losic, B., Schaefer, A. (2018) Epigenetic regulation of brain region-specific microglia clearance activity. Nat Neurosci. 21(8):1049-1060

Bellutti, F., Tigan, AS., Nebenfuehr, S., Dolezal, M., Zojer, M., Grausenburger, R., Hartenberger, S., Kollmann, S., Doma, E., Prchal-Murphy, M., Uras, IZ., Höllein, A., Neuberg, DS., Ebert, BL., Ringler, A., Mueller, AC., Loizou, JI., Hinds, PW., Vogl, C., Heller, G., Kubicek, S., Zuber, J., Malumbres, M., Farlik, M., Villunger, A., Kollmann, K., Sexl, V. (2018) CDK6 Antagonizes p53-Induced Responses during Tumorigenesis. Cancer Discov. 8(7):884-897

Benke, S., Agerer, B., Haas, L., Stöger, M., Lercher, A., Gabler, L., Kiss, I., Scinicariello, S., Berger, W., Bergthaler, A., Obenauf, AC., Versteeg, GA. (2018) Human tripartite motif protein 52 is required for cell context-dependent proliferation. Oncotarget. 9(17):13565-13581

Bönelt, P., Wöhner, M., Minnich, M., Tagoh, H., Fischer, M., Jaritz, M., Kavirayani, A., Garimella, M., Karlsson, MC., Busslinger, M. (2018) Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells. EMBO J.

Cai, Y., Hossain, MJ., Hériché, JK., Politi, AZ., Walther, N., Koch, B., Wachsmuth, M., Nijmeijer, B., Kueblbeck, M., Martinic-Kavur, M., Ladurner, R., Alexander, S., Peters, JM., Ellenberg, J. (2018) Experimental and computational framework for a dynamic protein atlas of human cell division. Nature. 561(7723):411-415

Catarino, RR., Stark, A. (2018) Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation. Genes Dev. 32(3-4):202-223

Corsini, NS., Peer, AM., Moeseneder, P., Roiuk, M., Burkard, TR., Theussl, HC., Moll, I., Knoblich, JA. (2018) Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 22(4):543-558.e12

Cronin, SJF., Seehus, C., Weidinger, A., Talbot, S., Reissig, S., Seifert, M., Pierson, Y., McNeill, E., Longhi, MS., Turnes, BL., Kreslavsky, T., Kogler, M., Hoffmann, D., Ticevic, M., da Luz Scheffer, D., Tortola, L., Cikes, D., Jais, A., Rangachari, M., Rao, S., Paolino, M., Novatchkova, M., Aichinger, M., Barrett, L., Latremoliere, A., Wirnsberger, G., Lametschwandtner, G., Busslinger, M., Zicha, S., Latini, A., Robson, SC., Waisman, A., Andrews, N., Costigan, M., Channon, KM., Weiss, G., Kozlov, AV., Tebbe, M., Johnsson, K., Woolf, CJ., Penninger, JM. (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature.

Doblmann, J., Dusberger, F., Imre, R., Hudecz, O., Stanek, F., Mechtler, K., Dürnberger, G. (2018) apQuant: Accurate Label-Free Quantification by Quality Filtering. J Proteome Res.

Dorfer, V., Maltsev, S., Winkler, S., Mechtler, K. (2018) CharmeRT: Boosting peptide identifications by chimeric spectra identification and retention time prediction. J Proteome Res.

Dorl, S., Winkler, S., Mechtler, K., Dorfer, V. (2018) PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search. J Proteome Res. 17(1):290-295

Ebner, P., Poetsch, I., Deszcz, L., Hoffmann, T., Zuber, J., Ikeda, F. (2018) The IAP family member BRUCE regulates autophagosome-lysosome fusion. Nat Commun. 9(1):599

Engels, S., Treiber, CD., Salzer, MC., Michalik, A., Ushakova, L., Keays, DA., Mouritsen, H., Heyers, D. (2018) Lidocaine is a nocebo treatment for trigeminally mediated magnetic orientation in birds. J R Soc Interface. 15(145)

Fei, JF., Lou, WP., Knapp, D., Murawala, P., Gerber, T., Taniguchi, Y., Nowoshilow, S., Khattak, S., Tanaka, EM. (2018) Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum). Nat Protoc. 13(12):2908-2943

Fitz, J., Neumann, T., Pavri, R. (2018) Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation. EMBO J. 37(8)

Fujimura, N., Kuzelova, A., Ebert, A., Strnad, H., Lachova, J., Machon, O., Busslinger, M., Kozmik, Z. (2018) Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation. Dev Biol. 433(1):47-60

Ganglberger, F., Kaczanowska, J., Penninger, JM., Hess, A., Bühler, K., Haubensak, W. (2018) Predicting functional neuroanatomical maps from fusing brain networks with genetic information. Neuroimage. 170:113-120

Gerber, T., Murawala, P., Knapp, D., Masselink, W., Schuez, M., Hermann, S., Gac-Santel, M., Nowoshilow, S., Kageyama, J., Khattak, S., Currie, JD., Camp, JG., Tanaka, EM., Treutlein, B. (2018) Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 362(6413)

Gerlach, D., Tontsch-Grunt, U., Baum, A., Popow, J., Scharn, D., Hofmann, MH., Engelhardt, H., Kaya, O., Beck, J., Schweifer, N., Gerstberger, T., Zuber, J., Savarese, F., Kraut, N. (2018) The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML. Oncogene. 37(20):2687-2701

Griessner, J., Pasieka, M., Böhm, V., Grössl, F., Kaczanowska, J., Pliota, P., Kargl, D., Werner, B., Kaouane, N., Strobelt, S., Kreitz, S., Hess, A., Haubensak, W. (2018) Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect. Mol Psychiatry.

Groessl, F., Munsch, T., Meis, S., Griessner, J., Kaczanowska, J., Pliota, P., Kargl, D., Badurek, S., Kraitsy, K., Rassoulpour, A., Zuber, J., Lessmann, V., Haubensak, W. (2018) Dorsal tegmental dopamine neurons gate associative learning of fear. Nat Neurosci. 21(7):952-962

Gstrein, T., Edwards, A., Přistoupilová, A., Leca, I., Breuss, M., Pilat-Carotta, S., Hansen, AH., Tripathy, R., Traunbauer, AK., Hochstoeger, T., Rosoklija, G., Repic, M., Landler, L., Stránecký, V., Dürnberger, G., Keane, TM., Zuber, J., Adams, DJ., Flint, J., Honzik, T., Gut, M., Beltran, S., Mechtler, K., Sherr, E., Kmoch, S., Gut, I., Keays, DA. (2018) Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 21(2):207-217

Gstrein, T., Edwards, A., Přistoupilová, A., Leca, I., Breuss, M., Pilat-Carotta, S., Hansen, AH., Tripathy, R., Traunbauer, AK., Hochstoeger, T., Rosoklija, G., Repic, M., Landler, L., Stránecký, V., Dürnberger, G., Keane, TM., Zuber, J., Adams, DJ., Flint, J., Honzik, T., Gut, M., Beltran, S., Mechtler, K., Sherr, E., Kmoch, S., Gut, I., Keays, DA. (2018) Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci.

Haas, L., Wiesner, T., Obenauf, AC. (2018) A new era of proactive melanoma therapy: hit hard, hit early. Br J Dermatol. 178(4):817-820

Haberle, V., Stark, A. (2018) Eukaryotic core promoters and the functional basis of transcription initiation. Nat Rev Mol Cell Biol.

Haselbach, D., Komarov, I., Agafonov, DE., Hartmuth, K., Graf, B., Dybkov, O., Urlaub, H., Kastner, B., Lührmann, R., Stark, H. (2018) Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex. Cell. 172(3):454-464.e11

Hellerschmied, D., Roessler, M., Lehner, A., Gazda, L., Stejskal, K., Imre, R., Mechtler, K., Dammermann, A., Clausen, T. (2018) UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins. Nat Commun. 9(1):484

Herberg, S., Gert, KR., Schleiffer, A., Pauli, A. (2018) The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Science. 361(6406):1029-1033

Holt, C., Campbell, M., Keays, DA., Edelman, N., Kapusta, A., Maclary, E., T Domyan, E., Suh, A., Warren, WC., Yandell, M., Gilbert, MTP., Shapiro, MD. (2018) Improved Genome Assembly and Annotation for the Rock Pigeon (Columba livia). G3 (Bethesda). 8(5):1391-1398

Ivanov, MP., Ladurner, R., Poser, I., Beveridge, R., Rampler, E., Hudecz, O., Novatchkova, M., Hériché, JK., Wutz, G., van der Lelij, P., Kreidl, E., Hutchins, JR., Axelsson-Ekker, H., Ellenberg, J., Hyman, AA., Mechtler, K., Peters, JM. (2018) The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion. EMBO J.

Kaplan, HS., Nichols, ALA., Zimmer, M. (2018) Sensorimotor integration in Caenorhabditis elegans: a reappraisal towards dynamic and distributed computations. Philos Trans R Soc Lond B Biol Sci. 373(1758)

Kaplan, HS., Zimmer, M. (2018) Sensorimotor Integration for Decision Making: How the Worm Steers. Neuron. 97(2):258-260

Kreslavsky, T., Wong, JB., Fischer, M., Skok, JA., Busslinger, M. (2018) Control of B-1a cell development by instructive BCR signaling. Curr Opin Immunol. 51:24-31

Landler, L., Keays, DA. (2018) Cryptochrome: The magnetosensor with a sinister side? PLoS Biol. 16(10):e3000018

Landler, L., Nimpf, S., Hochstoeger, T., Nordmann, GC., Papadaki-Anastasopoulou, A., Keays, DA. (2018) Comment on "Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans". Elife. 7

Malkemper, EP., Mason, MJ., Kagerbauer, D., Nimpf, S., Keays, DA. (2018) Ectopic otoconial formation in the lagena of the pigeon inner ear. Biol Open. 7(8)

Matsushima, W., Herzog, VA., Neumann, T., Gapp, K., Zuber, J., Ameres, SL., Miska, EA. (2018) SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting. Development. 145(13)

Medelnik, JP., Roensch, K., Okawa, S., Del Sol, A., Chara, O., Mchedlishvili, L., Tanaka, EM. (2018) Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells. Stem Cell Reports. 10(6):1751-1765

Milanovic, M., Fan, DNY., Belenki, D., Däbritz, JHM., Zhao, Z., Yu, Y., Dörr, JR., Dimitrova, L., Lenze, D., Monteiro Barbosa, IA., Mendoza-Parra, MA., Kanashova, T., Metzner, M., Pardon, K., Reimann, M., Trumpp, A., Dörken, B., Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G., Lee, S., Schmitt, CA. (2018) Senescence-associated reprogramming promotes cancer stemness. Nature. 553(7686):96-100

Mueller, N., Wicklein, D., Eisenwort, G., Jawhar, M., Berger, D., Stefanzl, G., Greiner, G., Boehm, A., Kornauth, C., Muellauer, L., Sehner, S., Hoermann, G., Sperr, WR., Staber, PB., Jaeger, U., Zuber, J., Arock, M., Schumacher, U., Reiter, A., Valent, P. (2018) CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis. Blood.

Muerdter, F., Boryń, ŁM., Woodfin, AR., Neumayr, C., Rath, M., Zabidi, MA., Pagani, M., Haberle, V., Kazmar, T., Catarino, RR., Schernhuber, K., Arnold, CD., Stark, A. (2018) Resolving systematic errors in widely used enhancer activity assays in human cells. Nat Methods. 15(2):141-149

Muhar, M., Ebert, A., Neumann, T., Umkehrer, C., Jude, J., Wieshofer, C., Rescheneder, P., Lipp, JJ., Herzog, VA., Reichholf, B., Cisneros, DA., Hoffmann, T., Schlapansky, MF., Bhat, P., von Haeseler, A., Köcher, T., Obenauf, AC., Popow, J., Ameres, SL., Zuber, J. (2018) SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 360(6390):800-805

Nowoshilow, S., Schloissnig, S., Fei, JF., Dahl, A., Pang, AWC., Pippel, M., Winkler, S., Hastie, AR., Young, G., Roscito, JG., Falcon, F., Knapp, D., Powell, S., Cruz, A., Cao, H., Habermann, B., Hiller, M., Tanaka, EM., Myers, EW. (2018) The axolotl genome and the evolution of key tissue formation regulators. Nature. 554(7690):50-55

Nowoshilow, S., Schloissnig, S., Fei, JF., Dahl, A., Pang, AWC., Pippel, M., Winkler, S., Hastie, AR., Young, G., Roscito, JG., Falcon, F., Knapp, D., Powell, S., Cruz, A., Cao, H., Habermann, B., Hiller, M., Tanaka, EM., Myers, EW. (2018) Author Correction: The axolotl genome and the evolution of key tissue formation regulators. Nature. 559(7712):E2

Oliveira, CR., Lemaitre, R., Murawala, P., Tazaki, A., Drechsel, DN., Tanaka, EM. (2018) Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration. Dev Biol. 433(2):262-275

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Nat Protoc. 13(3):478-494

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Reply to 'Defining distance restraints in HADDOCK'. Nat Protoc. 13(7):1503-1505

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Nat Protoc.

Osman, K., Yang, J., Roitinger, E., Lambing, C., Heckmann, S., Howell, E., Cuacos, M., Imre, R., Dürnberger, G., Mechtler, K., Armstrong, S., Franklin, FCH. (2018) Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis. Plant J. 93(1):17-33

Peter, B., Bibi, S., Eisenwort, G., Wingelhofer, B., Berger, D., Stefanzl, G., Blatt, K., Herrmann, H., Hadzijusufovic, E., Hoermann, G., Hoffmann, T., Schwaab, J., Jawhar, M., Willmann, M., Sperr, WR., Zuber, J., Sotlar, K., Horny, HP., Moriggl, R., Reiter, A., Arock, M., Valent, P. (2018) Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells. Leukemia. 32(4):1016-1022

Plaschka, C., Lin, PC., Charenton, C., Nagai, K. (2018) Prespliceosome structure provides insights into spliceosome assembly and regulation. Nature. 559(7714):419-422

Pliota, P., Böhm, V., Grössl, F., Griessner, J., Valenti, O., Kraitsy, K., Kaczanowska, J., Pasieka, M., Lendl, T., Deussing, JM., Haubensak, W. (2018) Stress peptides sensitize fear circuitry to promote passive coping. Mol Psychiatry.

Rojo Romanos, T., Ng, L., Pocock, R. (2018) Behavioral Assays to Study Oxygen and Carbon Dioxide Sensing in Caenorhabditis elegans. Bio Protoc. 8(1)

Rouse, T., Aubry, G., Cho, Y., Zimmer, M., Lu, H. (2018) A programmable platform for sub-second multichemical dynamic stimulation and neuronal functional imaging in C. elegans. Lab Chip. 18(3):505-513

Sanyal, S., Molnarova, L., Richterova, J., Huraiova, B., Benko, Z., Polakova, S., Cipakova, I., Sevcovicova, A., Gaplovska-Kysela, K., Mechtler, K., Cipak, L., Gregan, J. (2018) Mutations that prevent methylation of cohesin render sensitivity to DNA damage. J Cell Sci.

Seehawer, M., Heinzmann, F., D'Artista, L., Harbig, J., Roux, PF., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., Rozenblum, N., Kang, TW., Chawla, R., Buch, T., Vucur, M., Roth, M., Zuber, J., Luedde, T., Sipos, B., Longerich, T., Heikenwälder, M., Wang, XW., Bischof, O., Zender, L. (2018) Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 562(7725):69-75

Silva, MCC., Wutz, G., Tachibana, K., Peters, JM. (2018) Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy. Methods Cell Biol. 144:287-305

Skocek, O., Nöbauer, T., Weilguny, L., Martínez Traub, F., Xia, CN., Molodtsov, MI., Grama, A., Yamagata, M., Aharoni, D., Cox, DD., Golshani, P., Vaziri, A. (2018) High-speed volumetric imaging of neuronal activity in freely moving rodents. Nat Methods.

Skocek, O., Nöbauer, T., Weilguny, L., Traub, FM., Xia, CN., Molodtsov, MI., Grama, A., Yamagata, M., Aharoni, D., Cox, DD., Golshani, P., Vaziri, A. (2018) Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents. Nat Methods. 15(6):469

Skora, S., Mende, F., Zimmer, M. (2018) Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans. Cell Rep. 22(4):953-966

Skucha, A., Ebner, J., Schmöllerl, J., Roth, M., Eder, T., César-Razquin, A., Stukalov, A., Vittori, S., Muhar, M., Lu, B., Aichinger, M., Jude, J., Müller, AC., Győrffy, B., Vakoc, CR., Valent, P., Bennett, KL., Zuber, J., Superti-Furga, G., Grebien, F. (2018) MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nat Commun. 9(1):1983

Smakowska-Luzan, E., Mott, GA., Parys, K., Stegmann, M., Howton, TC., Layeghifard, M., Neuhold, J., Lehner, A., Kong, J., Grünwald, K., Weinberger, N., Satbhai, SB., Mayer, D., Busch, W., Madalinski, M., Stolt-Bergner, P., Provart, NJ., Mukhtar, MS., Zipfel, C., Desveaux, D., Guttman, DS., Belkhadir, Y. (2018) An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Nature. 553(7688):342-346

Stadlmann, J., Hoi, DM., Taubenschmid, J., Mechtler, K., Penninger, JM. (2018) Analysis of PNGase F-resistant N-glycopeptides using SugarQb for Proteome Discoverer 2.1 reveals cryptic substrate specificities. Proteomics. :e1700436

Stanyte, R., Nuebler, J., Blaukopf, C., Hoefler, R., Stocsits, R., Peters, JM., Gerlich, DW. (2018) Dynamics of sister chromatid resolution during cell cycle progression. J Cell Biol.

Szappanos, D., Tschismarov, R., Perlot, T., Westermayer, S., Fischer, K., Platanitis, E., Kallinger, F., Novatchkova, M., Lassnig, C., Müller, M., Sexl, V., Bennett, KL., Foong-Sobis, M., Penninger, JM., Decker, T. (2018) The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 14(11):e1007397

Tanaka, EM. (2018) Regenerating tissues. Science. 360(6387):374-375

Tripathy, R., Leca, I., van Dijk, T., Weiss, J., van Bon, BW., Sergaki, MC., Gstrein, T., Breuss, M., Tian, G., Bahi-Buisson, N., Paciorkowski, AR., Pagnamenta, AT., Wenninger-Weinzierl, A., Martinez-Reza, MF., Landler, L., Lise, S., Taylor, JC., Terrone, G., Vitiello, G., Del Giudice, E., Brunetti-Pierri, N., D'Amico, A., Reymond, A., Voisin, N., Bernstein, JA., Farrelly, E., Kini, U., Leonard, TA., Valence, S., Burglen, L., Armstrong, L., Hiatt, SM., Cooper, GM., Aldinger, KA., Dobyns, WB., Mirzaa, G., Pierson, TM., Baas, F., Chelly, J., Cowan, NJ., Keays, DA. (2018) Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 100(6):1354-1368.e5

Watson, ER., Brown, NG., Peters, JM., Stark, H., Schulman, BA. (2018) Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. Trends Cell Biol.

Weisenburger, S., Vaziri, A. (2018) A Guide to Emerging Technologies for Large-Scale and Whole-Brain Optical Imaging of Neuronal Activity. Annu Rev Neurosci.

Weissmann, F., Peters, JM. (2018) Expressing Multi-subunit Complexes Using biGBac. Methods Mol Biol. 1764:329-343

Yang, T., Cui, H., Wen, M., Zuber, J., Kogan, SC., Wei, G. (2018) TCEA1 regulates the proliferative potential of mouse myeloid cells. Exp Cell Res.

2017

Aarts, M., Georgilis, A., Beniazza, M., Beolchi, P., Banito, A., Carroll, T., Kulisic, M., Kaemena, DF., Dharmalingam, G., Martin, N., Reik, W., Zuber, J., Kaji, K., Chandra, T., Gil, J. (2017) Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence. Genes Dev. 31(20):2085-2098

Adams, FF., Heckl, D., Hoffmann, T., Talbot, SR., Kloos, A., Thol, F., Heuser, M., Zuber, J., Schambach, A., Schwarzer, A. (2017) An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries. Biomaterials. 139:102-115

Alberti, C., Cochella, L. (2017) A framework for understanding the roles of miRNAs in animal development. Development. 144(14):2548-2559

Andergassen, D., Dotter, CP., Wenzel, D., Sigl, V., Bammer, PC., Muckenhuber, M., Mayer, D., Kulinski, TM., Theussl, HC., Penninger, JM., Bock, C., Barlow, DP., Pauler, FM., Hudson, QJ. (2017) Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression. Elife. 6

Arnold, CD., Zabidi, MA., Pagani, M., Rath, M., Schernhuber, K., Kazmar, T., Stark, A. (2017) Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution. Nat Biotechnol. 35(2):136-144

Beckham, KS., Ciccarelli, L., Bunduc, CM., Mertens, HD., Ummels, R., Lugmayr, W., Mayr, J., Rettel, M., Savitski, MM., Svergun, DI., Bitter, W., Wilmanns, M., Marlovits, TC., Parret, AH., Houben, EN. (2017) Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis. Nat Microbiol. 2:17047

Breuss, MW., Hansen, AH., Landler, L., Keays, DA. (2017) Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition. Behav Brain Res. 323:47-55

Breuss, MW., Leca, I., Gstrein, T., Hansen, AH., Keays, DA. (2017) Tubulins and brain development - The origins of functional specification. Mol Cell Neurosci.

Breuss, MW., Nguyen, T., Srivatsan, A., Leca, I., Tian, G., Fritz, T., Hansen, AH., Musaev, D., McEvoy-Venneri, J., James, KN., Rosti, RO., Scott, E., Tan, U., Kolodner, RD., Cowan, NJ., Keays, DA., Gleeson, JG. (2017) Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 26(2):258-269

Busslinger, GA., Stocsits, RR., van der Lelij, P., Axelsson, E., Tedeschi, A., Galjart, N., Peters, JM. (2017) Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl. Nature. 544(7651):503-507

Catarino, RR., Neumayr, C., Stark, A. (2017) Promoting transcription over long distances. Nat Genet. 49(7):972-973

Conti, V., Carabalona, A., Pallesi-Pocachard, E., Leventer, RJ., Schaller, F., Parrini, E., Deparis, AA., Watrin, F., Buhler, E., Novara, F., Lise, S., Pagnamenta, AT., Kini, U., Taylor, JC., Zuffardi, O., Represa, A., Keays, DA., Guerrini, R., Falace, A., Cardoso, C. (2017) A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations. J Vis Exp. (130)

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2013

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Fischer, RM., Fontinha, BM., Kirchmaier, S., Steger, J., Bloch, S., Inoue, D., Panda, S., Rumpel, S., Tessmar-Raible, K. (2013) Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain. PLoS Biol. 11(6):e1001585

Frelin, C., Herrington, R., Janmohamed, S., Barbara, M., Tran, G., Paige, CJ., Benveniste, P., Zuñiga-Pflücker, JC., Souabni, A., Busslinger, M., Iscove, NN. (2013) GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nat Immunol. 14(10):1037-44

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Frye, JJ., Brown, NG., Petzold, G., Watson, ER., Grace, CR., Nourse, A., Jarvis, MA., Kriwacki, RW., Peters, JM., Stark, H., Schulman, BA. (2013) Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown. Nat Struct Mol Biol. 20(7):827-35

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Gazda, L., Pokrzywa, W., Hellerschmied, D., Löwe, T., Forné, I., Mueller-Planitz, F., Hoppe, T., Clausen, T. (2013) The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans. Cell. 152(1-2):183-95

Gramstrup Petersen, J., Rojo Romanos, T., Juozaityte, V., Redo Riveiro, A., Hums, I., Traunmüller, L., Zimmer, M., Pocock, R. (2013) EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans. PLoS Genet. 9(5):e1003511

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Jászai, J., Graupner, S., Tanaka, EM., Funk, RH., Huttner, WB., Brand, M., Corbeil, D. (2013) Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain. PLoS One. 8(5):e63457

Jüschke, C., Dohnal, I., Pichler, P., Harzer, H., Swart, R., Ammerer, G., Mechtler, K., Knoblich, JA. (2013) Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation. Genome Biol. 14(11):r133

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Khattak, S., Sandoval-Guzmán, T., Stanke, N., Protze, S., Tanaka, EM., Lindemann, D. (2013) Foamy virus for efficient gene transfer in regeneration studies. BMC Dev Biol. 13:17

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Kragl, M., Roensch, K., Nüsslein, I., Tazaki, A., Taniguchi, Y., Tarui, H., Hayashi, T., Agata, K., Tanaka, EM. (2013) Muscle and connective tissue progenitor populations show distinct Twist1 and Twist3 expression profiles during axolotl limb regeneration. Dev Biol. 373(1):196-204

Lampert, F., Mieck, C., Alushin, GM., Nogales, E., Westermann, S. (2013) Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes. J Cell Biol. 200(1):21-30

Lauwers, M., Pichler, P., Edelman, NB., Resch, GP., Ushakova, L., Salzer, MC., Heyers, D., Saunders, M., Shaw, J., Keays, DA. (2013) An iron-rich organelle in the cuticular plate of avian hair cells. Curr Biol. 23(10):924-9

Lin, CY., Chuang, CC., Hua, TE., Chen, CC., Dickson, BJ., Greenspan, RJ., Chiang, AS. (2013) A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain. Cell Rep. 3(5):1739-53

Lin, HH., Chu, LA., Fu, TF., Dickson, BJ., Chiang, AS. (2013) Parallel neural pathways mediate CO2 avoidance responses in Drosophila. Science. 340(6138):1338-41

Mair, B., Popow, J., Mechtler, K., Weitzer, S., Martinez, J. (2013) Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components. Biochem Soc Trans. 41(4):831-7

Maisak, MS., Haag, J., Ammer, G., Serbe, E., Meier, M., Leonhardt, A., Schilling, T., Bahl, A., Rubin, GM., Nern, A., Dickson, BJ., Reiff, DF., Hopp, E., Borst, A. (2013) A directional tuning map of Drosophila elementary motion detectors. Nature. 500(7461):212-6

Malvezzi, F., Litos, G., Schleiffer, A., Heuck, A., Mechtler, K., Clausen, T., Westermann, S. (2013) A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors. EMBO J. 32(3):409-23

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Mastny, M., Heuck, A., Kurzbauer, R., Heiduk, A., Boisguerin, P., Volkmer, R., Ehrmann, M., Rodrigues, CD., Rudner, DZ., Clausen, T. (2013) CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis. Cell. 155(3):647-58

Medvedovic, J., Ebert, A., Tagoh, H., Tamir, IM., Schwickert, TA., Novatchkova, M., Sun, Q., Huis In 't Veld, PJ., Guo, C., Yoon, HS., Denizot, Y., Holwerda, SJ., de Laat, W., Cogné, M., Shi, Y., Alt, FW., Busslinger, M. (2013) Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire. Immunity. 39(2):229-44

Moczulska, KE., Tinter-Thiede, J., Peter, M., Ushakova, L., Wernle, T., Bathellier, B., Rumpel, S. (2013) Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall. Proc Natl Acad Sci U S A. 110(45):18315-20

Moruz, L., Pichler, P., Stranzl, T., Mechtler, K., Käll, L. (2013) Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics. Anal Chem. 85(16):7777-85

Nacu, E., Glausch, M., Le, HQ., Damanik, FF., Schuez, M., Knapp, D., Khattak, S., Richter, T., Tanaka, EM. (2013) Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl. Development. 140(3):513-8

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Ohtsuka, N., Badurek, S., Busslinger, M., Benes, FM., Minichiello, L., Rudolph, U. (2013) GABAergic neurons regulate lateral ventricular development via transcription factor Pax5. Genesis. 51(4):234-45

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Reiter, W., Klopf, E., De Wever, V., Anrather, D., Petryshyn, A., Roetzer, A., Niederacher, G., Roitinger, E., Dohnal, I., Görner, W., Mechtler, K., Brocard, C., Schüller, C., Ammerer, G. (2013) Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment. Mol Cell Biol. 33(5):1057-72

Roensch, K., Tazaki, A., Chara, O., Tanaka, EM. (2013) Progressive specification rather than intercalation of segments during limb regeneration. Science. 342(6164):1375-9

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Schrödel, T., Prevedel, R., Aumayr, K., Zimmer, M., Vaziri, A. (2013) Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light. Nat Methods. 10(10):1013-20

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Skora, S., Zimmer, M. (2013) Life(span) in balance: oxygen fuels a sophisticated neural network for lifespan homeostasis in C. elegans. EMBO J. 32(11):1499-501

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Yáñez-Cuna, JO., Kvon, EZ., Stark, A. (2013) Deciphering the transcriptional cis-regulatory code. Trends Genet. 29(1):11-22

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2012

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Hadjieconomou, D., Rotkopf, S., Alexandre, C., Bell, DM., Dickson, BJ., Salecker, I. (2011) Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. Nat Methods. 8(3):260-6

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Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2011) Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin. Virology. 412(1):55-67

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Köcher, T. (2011) Comment on 'Jobs for the boys'. EMBO Rep. 12(6):488

Köcher, T., Pichler, P., Mazanek, M., Swart, R., Mechtler, K. (2011) Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications. Anal Bioanal Chem. 400(8):2339-47

Köcher, T., Pichler, P., Swart, R., Mechtler, K. (2011) Quality control in LC-MS/MS. Proteomics. 11(6):1026-30

Köcher, T., Swart, R., Mechtler, K. (2011) Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides. Anal Chem. 83(7):2699-704

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Lampert, F., Westermann, S. (2011) A blueprint for kinetochores - new insights into the molecular mechanics of cell division. Nat Rev Mol Cell Biol. 12(7):407-12

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Loewenstein, Y., Kuras, A., Rumpel, S. (2011) Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo. J Neurosci. 31(26):9481-8

Lyashenko, N., Winter, M., Migliorini, D., Biechele, T., Moon, RT., Hartmann, C. (2011) Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol. 13(7):753-61

Malle, E., Zhou, H., Neuhold, J., Spitzenberger, B., Klepsch, F., Pollak, T., Bergner, O., Ecker, GF., Stolt-Bergner, PC. (2011) Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues. J Biol Chem. 286(26):23121-31

McManus, S., Ebert, A., Salvagiotto, G., Medvedovic, J., Sun, Q., Tamir, I., Jaritz, M., Tagoh, H., Busslinger, M. (2011) The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J. 30(12):2388-404

Mechtcheriakova, D., Sobanov, Y., Holtappels, G., Bajna, E., Svoboda, M., Jaritz, M., Bachert, C., Jensen-Jarolim, E. (2011) Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. PLoS One. 6(10):e25611

Medvedovic, J., Ebert, A., Tagoh, H., Busslinger, M. (2011) Pax5: a master regulator of B cell development and leukemogenesis. Adv Immunol. 111:179-206

Merdanovic, M., Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) Protein quality control in the bacterial periplasm. Annu Rev Microbiol. 65:149-68

Nacu, E., Tanaka, EM. (2011) Limb regeneration: a new development? Annu Rev Cell Dev Biol. 27:409-40

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Ng, K., Daigle, N., Bancaud, A., Ohhata, T., Humphreys, P., Walker, R., Ellenberg, J., Wutz, A. (2011) A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells. Mol Biol Cell. 22(14):2634-45

Pappu, KS., Morey, M., Nern, A., Spitzweck, B., Dickson, BJ., Zipursky, SL. (2011) Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development. Proc Natl Acad Sci U S A. 108(18):7571-6

Pichler, P., Köcher, T., Holzmann, J., Möhring, T., Ammerer, G., Mechtler, K. (2011) Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell. Anal Chem. 83(4):1469-74

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Qin, H., Suzuki, K., Nakata, M., Chikuma, S., Izumi, N., Huong, le T., Maruya, M., Fagarasan, S., Busslinger, M., Honjo, T., Nagaoka, H. (2011) Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One. 6(12):e29141

Resch, GP., Brandstetter, M., Pickl-Herk, AM., Königsmaier, L., Wonesch, VI., Urban, E. (2011) Immersion freezing of biological specimens: rationale, principles, and instrumentation. Cold Spring Harb Protoc. 2011(7):778-82

Sampaio, JL., Gerl, MJ., Klose, C., Ejsing, CS., Beug, H., Simons, K., Shevchenko, A. (2011) Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A. 108(5):1903-7

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Schönbauer, C., Distler, J., Jährling, N., Radolf, M., Dodt, HU., Frasch, M., Schnorrer, F. (2011) Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479(7373):406-9

Schraidt, O., Marlovits, TC. (2011) Three-dimensional model of Salmonella's needle complex at subnanometer resolution. Science. 331(6021):1192-5

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2010

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Agrelo, R., Wutz, A. (2010) X inactivation and disease. Semin Cell Dev Biol. 21(2):194-200

Alpert, AJ., Petritis, K., Kangas, L., Smith, RD., Mechtler, K., Mitulović, G., Mohammed, S., Heck, AJ. (2010) Peptide orientation affects selectivity in ion-exchange chromatography. Anal Chem. 82(12):5253-9

Antos, CL., Tanaka, EM. (2010) Vertebrates that regenerate as models for guiding stem cels. Adv Exp Med Biol. 695:184-214

Baudrimont, A., Penkner, A., Woglar, A., Machacek, T., Wegrostek, C., Gloggnitzer, J., Fridkin, A., Klein, F., Gruenbaum, Y., Pasierbek, P., Jantsch, V. (2010) Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans. PLoS Genet. 6(11):e1001219

Baumann, CL., Aspalter, IM., Sharif, O., Pichlmair, A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, KL., Colinge, J., Knapp, S., Superti-Furga, G. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med. 207(12):2689-701

Berg, DA., Kirkham, M., Beljajeva, A., Knapp, D., Habermann, B., Ryge, J., Tanaka, EM., Simon, A. (2010) Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain. Development. 137(24):4127-34

Bouchard, M., de Caprona, D., Busslinger, M., Xu, P., Fritzsch, B. (2010) Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol. 10:89

Braglia, P., Heindl, K., Schleiffer, A., Martinez, J., Proudfoot, NJ. (2010) Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I. EMBO Rep. 11(10):758-64

Braun, A., Breuss, M., Salzer, MC., Flint, J., Cowan, NJ., Keays, DA. (2010) Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 86(5):819-22; author reply 822-3

Cachero, S., Ostrovsky, AD., Yu, JY., Dickson, BJ., Jefferis, GS. (2010) Sexual dimorphism in the fly brain. Curr Biol. 20(18):1589-601

Csiszar, A., Vogelsang, E., Beug, H., Leptin, M. (2010) A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol. 30(8):2017-27

Dickson, BJ., Zou, Y. (2010) Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol. 2(8):a002055

El-Kasaby, A., Just, H., Malle, E., Stolt-Bergner, PC., Sitte, HH., Freissmuth, M., Kudlacek, O. (2010) Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem. 285(50):39201-10

Elsayad, K., Heinze, KG. (2010) Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks Physical Review A. 81(5)

Elsayad, K., Heinze, KG. (2010) Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films Proc. SPIE. 7757:77573L

Elsayad, K., Urich, A., Unterrainer, K., Heinze, KG. (2010) Fast near-field imaging of spectrally broad sources using layered metallic structures Proc. SPIE. 7757:77573M

Eskeland, R., Leeb, M., Grimes, GR., Kress, C., Boyle, S., Sproul, D., Gilbert, N., Fan, Y., Skoultchi, AI., Wutz, A., Bickmore, WA. (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 38(3):452-64

Feng, W., Yonezawa, M., Ye, J., Jenuwein, T., Grummt, I. (2010) PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol. 17(4):445-50

Friedbichler, K., Kerenyi, MA., Kovacic, B., Li, G., Hoelbl, A., Yahiaoui, S., Sexl, V., Müllner, EW., Fajmann, S., Cerny-Reiterer, S., Valent, P., Beug, H., Gouilleux, F., Bunting, KD., Moriggl, R. (2010) Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood. 116(9):1548-58

Fuchs, A., Inthal, A., Herrmann, D., Cheng, S., Nakatomi, M., Peters, H., Neubüser, A. (2010) Regulation of Tbx22 during facial and palatal development. Dev Dyn. 239(11):2860-74

Fujimori, S., Novak, H., Weissenböck, M., Jussila, M., Gonçalves, A., Zeller, R., Galloway, J., Thesleff, I., Hartmann, C. (2010) Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 348(1):97-106

Galkin, VE., Schmied, WH., Schraidt, O., Marlovits, TC., Egelman, EH. (2010) The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system. J Mol Biol. 396(5):1392-7

Gin, E., Tanaka, EM., Brusch, L. (2010) A model for cyst lumen expansion and size regulation via fluid secretion. J Theor Biol. 264(3):1077-88

Grausenburger, R., Bilic, I., Boucheron, N., Zupkovitz, G., El-Housseiny, L., Tschismarov, R., Zhang, Y., Rembold, M., Gaisberger, M., Hartl, A., Epstein, MM., Matthias, P., Seiser, C., Ellmeier, W. (2010) Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol. 185(6):3489-97

Haider, S., Wagner, M., Schmid, MC., Sixt, BS., Christian, JG., Häcker, G., Pichler, P., Mechtler, K., Müller, A., Baranyi, C., Toenshoff, ER., Montanaro, J., Horn, M. (2010) Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae. Mol Microbiol. 77(3):687-700

Hasenbein, S., Meltzer, M., Hauske, P., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2010) Conversion of a regulatory into a degradative protease. J Mol Biol. 397(4):957-66

Haubner, BJ., Neely, GG., Voelkl, JG., Damilano, F., Kuba, K., Imai, Y., Komnenovic, V., Mayr, A., Pachinger, O., Hirsch, E., Penninger, JM., Metzler, B. (2010) PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway. PLoS One. 5(2):e9350

Heinz, E., Pichler, P., Heinz, C., Op den Camp, HJ., Toenshoff, ER., Ammerer, G., Mechtler, K., Wagner, M., Horn, M. (2010) Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies. Proteomics. 10(24):4363-76

Herrmann, D., Ferrer-Vaquer, A., Lahsnig, C., Firnberg, N., Leibbrandt, A., Neubüser, A. (2010) Expression and regulation of ANTXR1 in the chick embryo. Dev Dyn. 239(2):680-7

Hnisz, D., Majer, O., Frohner, IE., Komnenovic, V., Kuchler, K. (2010) The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog. 6(5):e1000889

Hoelbl, A., Schuster, C., Kovacic, B., Zhu, B., Wickre, M., Hoelzl, MA., Fajmann, S., Grebien, F., Warsch, W., Stengl, G., Hennighausen, L., Poli, V., Beug, H., Moriggl, R., Sexl, V. (2010) Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med. 2(3):98-110

Huang, J., Dorsey, J., Chuikov, S., Pérez-Burgos, L., Zhang, X., Jenuwein, T., Reinberg, D., Berger, SL. (2010) G9a and Glp methylate lysine 373 in the tumor suppressor p53. J Biol Chem. 285(13):9636-41

Huber, MA., Maier, HJ., Alacakaptan, M., Wiedemann, E., Braunger, J., Boehmelt, G., Madwed, JB., Young, ER., Marshall, DR., Pehamberger, H., Wirth, T., Kraut, N., Beug, H. (2010) BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. Genes Cancer. 1(2):101-14

Hutchins, JR., Toyoda, Y., Hegemann, B., Poser, I., Hériché, JK., Sykora, MM., Augsburg, M., Hudecz, O., Buschhorn, BA., Bulkescher, J., Conrad, C., Comartin, D., Schleiffer, A., Sarov, M., Pozniakovsky, A., Slabicki, MM., Schloissnig, S., Steinmacher, I., Leuschner, M., Ssykor, A., Lawo, S., Pelletier, L., Stark, H., Nasmyth, K., Ellenberg, J., Durbin, R., Buchholz, F., Mechtler, K., Hyman, AA., Peters, JM. (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 328(5978):593-9

Ishizaki, K., Suzuki, K., Mito, T., Tanaka, EM., Sato, S. (2010) Morphologic, functional, and occlusal characterization of mandibular lateral displacement malocclusion. Am J Orthod Dentofacial Orthop. 137(4):454.e1-9; discussion 454-5

Johnson, BA., Kahler, DJ., Baban, B., Chandler, PR., Kang, B., Shimoda, M., Koni, PA., Pihkala, J., Vilagos, B., Busslinger, M., Munn, DH., Mellor, AL. (2010) B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc Natl Acad Sci U S A. 107(23):10644-8

Karginov, FV., Cheloufi, S., Chong, MM., Stark, A., Smith, AD., Hannon, GJ. (2010) Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases. Mol Cell. 38(6):781-8

Katis, VL., Lipp, JJ., Imre, R., Bogdanova, A., Okaz, E., Habermann, B., Mechtler, K., Nasmyth, K., Zachariae, W. (2010) Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis. Dev Cell. 18(3):397-409

Keays, DA., Cleak, J., Huang, GJ., Edwards, A., Braun, A., Treiber, CD., Pidsley, R., Flint, J. (2010) The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus. Dev Neurosci. 32(4):268-77

Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2010) Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway. J Virol. 84(8):3984-92

Kim, YJ., Bartalska, K., Audsley, N., Yamanaka, N., Yapici, N., Lee, JY., Kim, YC., Markovic, M., Isaac, E., Tanaka, Y., Dickson, BJ. (2010) MIPs are ancestral ligands for the sex peptide receptor. Proc Natl Acad Sci U S A. 107(14):6520-5

Krojer, T., Sawa, J., Huber, R., Clausen, T. (2010) HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol. 17(7):844-52

Kuçi, S., Kuçi, Z., Kreyenberg, H., Deak, E., Pütsch, K., Huenecke, S., Amara, C., Koller, S., Rettinger, E., Grez, M., Koehl, U., Latifi-Pupovci, H., Henschler, R., Tonn, T., von Laer, D., Klingebiel, T., Bader, P. (2010) CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties. Haematologica. 95(4):651-9

Lampert, F., Hornung, P., Westermann, S. (2010) The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex. J Cell Biol. 189(4):641-9

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Hill, TP., Taketo, MM., Birchmeier, W., Hartmann, C. (2006) Multiple roles of mesenchymal beta-catenin during murine limb patterning. Development. 133(7):1219-29

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Ihling, C., Schmidt, A., Kalkhof, S., Schulz, DM., Stingl, C., Mechtler, K., Haack, M., Beck-Sickinger, AG., Cooper, DM., Sinz, A. (2006) Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex. J Am Soc Mass Spectrom. 17(8):1100-13

Janda, E., Nevolo, M., Lehmann, K., Downward, J., Beug, H., Grieco, M. (2006) Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene. 25(54):7117-30

Jechlinger, M., Sommer, A., Moriggl, R., Seither, P., Kraut, N., Capodiecci, P., Donovan, M., Cordon-Cardo, C., Beug, H., Grünert, S. (2006) Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest. 116(6):1561-70

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Jones, DH., Nakashima, T., Sanchez, OH., Kozieradzki, I., Komarova, SV., Sarosi, I., Morony, S., Rubin, E., Sarao, R., Hojilla, CV., Komnenovic, V., Kong, YY., Schreiber, M., Dixon, SJ., Sims, SM., Khokha, R., Wada, T., Penninger, JM. (2006) Regulation of cancer cell migration and bone metastasis by RANKL. Nature. 440(7084):692-6

Kovacic, B., Stoiber, D., Moriggl, R., Weisz, E., Ott, RG., Kreibich, R., Levy, DE., Beug, H., Freissmuth, M., Sexl, V. (2006) STAT1 acts as a tumor promoter for leukemia development. Cancer Cell. 10(1):77-87

Kraft, C., Gmachl, M., Peters, JM. (2006) Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex. Methods. 38(1):39-51

Kubicek, S., Schotta, G., Lachner, M., Sengupta, R., Kohlmaier, A., Perez-Burgos, L., Linderson, Y., Martens, JH., O'Sullivan, RJ., Fodor, BD., Yonezawa, M., Peters, AH., Jenuwein, T. (2006) The role of histone modifications in epigenetic transitions during normal and perturbed development. Ernst Schering Res Found Workshop. (57):1-27

Kudo, NR., Wassmann, K., Anger, M., Schuh, M., Wirth, KG., Xu, H., Helmhart, W., Kudo, H., McKay, M., Maro, B., Ellenberg, J., de Boer, P., Nasmyth, K. (2006) Resolution of chiasmata in oocytes requires separase-mediated proteolysis. Cell. 126(1):135-46

Kueng, S., Hegemann, B., Peters, BH., Lipp, JJ., Schleiffer, A., Mechtler, K., Peters, JM. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell. 127(5):955-67

Kvitsiani, D., Dickson, BJ. (2006) Shared neural circuitry for female and male sexual behaviours in Drosophila. Curr Biol. 16(10):R355-6

Kyewski, B., Klein, L. (2006) A central role for central tolerance. Annu Rev Immunol. 24:571-606

Lénárt, P., Peters, JM. (2006) Checkpoint activation: don't get mad too much. Curr Biol. 16(11):R412-4

Leuschner, PJ., Ameres, SL., Kueng, S., Martinez, J. (2006) Cleavage of the siRNA passenger strand during RISC assembly in human cells. EMBO Rep. 7(3):314-20

McGarvey, KM., Fahrner, JA., Greene, E., Martens, J., Jenuwein, T., Baylin, SB. (2006) Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state. Cancer Res. 66(7):3541-9

Mitulovic, G., Mechtler, K. (2006) HPLC techniques for proteomics analysis--a short overview of latest developments. Brief Funct Genomic Proteomic. 5(4):249-60

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Mujezinovic, N., Raidl, G., Hutchins, JR., Peters, JM., Mechtler, K., Eisenhaber, F. (2006) Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise. Proteomics. 6(19):5117-31

Novatchkova, M., Schneider, G., Fritz, R., Eisenhaber, F., Schleiffer, A. (2006) DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity. Nucleic Acids Res. 34(Web Server issue):W214-8

Obernosterer, G., Leuschner, PJ., Alenius, M., Martinez, J. (2006) Post-transcriptional regulation of microRNA expression. RNA. 12(7):1161-7

Peters, JM. (2006) The anaphase promoting complex/cyclosome: a machine designed to destroy. Nat Rev Mol Cell Biol. 7(9):644-56

Petronczki, M., Matos, J., Mori, S., Gregan, J., Bogdanova, A., Schwickart, M., Mechtler, K., Shirahige, K., Zachariae, W., Nasmyth, K. (2006) Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1. Cell. 126(6):1049-64

Rangachari, M., Mauermann, N., Marty, RR., Dirnhofer, S., Kurrer, MO., Komnenovic, V., Penninger, JM., Eriksson, U. (2006) T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med. 203(8):2009-19

Resch, GP., Small, JV., Goldie, KN. (2006) Electron Microscopy of Extracted Cytoskeletons: Negative Staining, Cryoelectron Microscopy and Correlation with Light Microscopy. Cell Biology - A Laboratory Handbook (J. E. Celis, ed.).

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Schneider, G., Neuberger, G., Wildpaner, M., Tian, S., Berezovsky, I., Eisenhaber, F. (2006) Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases. BMC Bioinformatics. 7:164

Schoeftner, S., Sengupta, AK., Kubicek, S., Mechtler, K., Spahn, L., Koseki, H., Jenuwein, T., Wutz, A. (2006) Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing. EMBO J. 25(13):3110-22

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Schubert, D., Primavesi, L., Bishopp, A., Roberts, G., Doonan, J., Jenuwein, T., Goodrich, J. (2006) Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27. EMBO J. 25(19):4638-49

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Sobkow, L., Epperlein, HH., Herklotz, S., Straube, WL., Tanaka, EM. (2006) A germline GFP transgenic axolotl and its use to track cell fate: dual origin of the fin mesenchyme during development and the fate of blood cells during regeneration. Dev Biol. 290(2):386-97

Später, D., Hill, TP., Gruber, M., Hartmann, C. (2006) Role of canonical Wnt-signalling in joint formation. Eur Cell Mater. 12:71-80

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2005

Ameyar-Zazoua, M., Wisniewska, MB., Bakiri, L., Wagner, EF., Yaniv, M., Weitzman, JB. (2005) AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene. Oncogene. 24(14):2298-306

Angelin-Duclos, C., Domenget, C., Kolbus, A., Beug, H., Jurdic, P., Samarut, J. (2005) Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development. 132(5):925-34

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