Publications | IMP Scientific Papers | Research Institute of Molecular Pathology (IMP)

The IMP publishes 60 to 90 scientific papers in international peer-review journals every year. This evidence for the productivity and high scientific standard of the IMP is listed here in full – a directory of all scientific publications by IMP scientists since the establishment of the institute, organised by years and research groups.

2019

Griss, J., Stanek, F., Hudecz, O., Dürnberger, G., Perez-Riverol, Y., Vizcaíno, JA., Mechtler, K. (2019) Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins. J Proteome Res.

Kamieniarz-Gdula, K., Gdula, MR., Panser, K., Nojima, T., Monks, J., Wiśniewski, JR., Riepsaame, J., Brockdorff, N., Pauli, A., Proudfoot, NJ. (2019) Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination. Mol Cell.

Lust, K., Tanaka, EM. (2019) A comparative perspective on brain regeneration in amphibians and teleost fish. Dev Neurobiol.

Malkemper, EP., Kagerbauer, D., Ushakova, L., Nimpf, S., Pichler, P., Treiber, CD., de Jonge, M., Shaw, J., Keays, DA. (2019) No evidence for a magnetite-based magnetoreceptor in the lagena of pigeons. Curr Biol. 29(1):R14-R15

Masselink, W., Reumann, D., Murawala, P., Pasierbek, P., Taniguchi, Y., Bonnay, F., Meixner, K., Knoblich, JA., Tanaka, EM. (2019) Broad applicability of a streamlined ethyl cinnamate-based clearing procedure. Development. 146(3)

Novikov, A., Fu, Y., Huang, W., Freeman, B., Patel, R., van Ginkel, C., Koepsell, H., Busslinger, M., Onishi, A., Nespoux, J., Vallon, V. (2019) SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1. Am J Physiol Renal Physiol. 316(1):F173-F185

Papanikos, F., Clément, JAJ., Testa, E., Ravindranathan, R., Grey, C., Dereli, I., Bondarieva, A., Valerio-Cabrera, S., Stanzione, M., Schleiffer, A., Jansa, P., Lustyk, D., Fei, JF., Adams, IR., Forejt, J., Barchi, M., de Massy, B., Toth, A. (2019) Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes. Mol Cell.

Stieger, CE., Doppler, P., Mechtler, K. (2019) Optimized fragmentation improves the identification of peptides cross-linked by MS-cleavable reagents. J Proteome Res.

Suskiewicz, MJ., Hajdusits, B., Beveridge, R., Heuck, A., Vu, LD., Kurzbauer, R., Hauer, K., Thoeny, V., Rumpel, K., Mechtler, K., Meinhart, A., Clausen, T. (2019) Structure of McsB, a protein kinase for regulated arginine phosphorylation. Nat Chem Biol. 15(5):510-518

Wimmer, RA., Leopoldi, A., Aichinger, M., Wick, N., Hantusch, B., Novatchkova, M., Taubenschmid, J., Hämmerle, M., Esk, C., Bagley, JA., Lindenhofer, D., Chen, G., Boehm, M., Agu, CA., Yang, F., Fu, B., Zuber, J., Knoblich, JA., Kerjaschki, D., Penninger, JM. (2019) Human blood vessel organoids as a model of diabetic vasculopathy. Nature. 565(7740):505-510

2018

Adams, FF., Hoffmann, T., Zuber, J., Heckl, D., Schambach, A., Schwarzer, A. (2018) Pooled Generation of Lentiviral Tetracycline-Regulated microRNA Embedded Short Hairpin RNA Libraries. Hum Gene Ther Methods. 29(1):16-29

Alberti, C., Manzenreither, RA., Sowemimo, I., Burkard, TR., Wang, J., Mahofsky, K., Ameres, SL., Cochella, L. (2018) Cell-type specific sequencing of microRNAs from complex animal tissues. Nat Methods. 15(4):283-289

Arnold, CD., Nemčko, F., Woodfin, AR., Wienerroither, S., Vlasova, A., Schleiffer, A., Pagani, M., Rath, M., Stark, A. (2018) A high-throughput method to identify trans-activation domains within transcription factor sequences. EMBO J.

Ayata, P., Badimon, A., Strasburger, HJ., Duff, MK., Montgomery, SE., Loh, YE., Ebert, A., Pimenova, AA., Ramirez, BR., Chan, AT., Sullivan, JM., Purushothaman, I., Scarpa, JR., Goate, AM., Busslinger, M., Shen, L., Losic, B., Schaefer, A. (2018) Epigenetic regulation of brain region-specific microglia clearance activity. Nat Neurosci. 21(8):1049-1060

Bellutti, F., Tigan, AS., Nebenfuehr, S., Dolezal, M., Zojer, M., Grausenburger, R., Hartenberger, S., Kollmann, S., Doma, E., Prchal-Murphy, M., Uras, IZ., Höllein, A., Neuberg, DS., Ebert, BL., Ringler, A., Mueller, AC., Loizou, JI., Hinds, PW., Vogl, C., Heller, G., Kubicek, S., Zuber, J., Malumbres, M., Farlik, M., Villunger, A., Kollmann, K., Sexl, V. (2018) CDK6 Antagonizes p53-Induced Responses during Tumorigenesis. Cancer Discov. 8(7):884-897

Benke, S., Agerer, B., Haas, L., Stöger, M., Lercher, A., Gabler, L., Kiss, I., Scinicariello, S., Berger, W., Bergthaler, A., Obenauf, AC., Versteeg, GA. (2018) Human tripartite motif protein 52 is required for cell context-dependent proliferation. Oncotarget. 9(17):13565-13581

Bönelt, P., Wöhner, M., Minnich, M., Tagoh, H., Fischer, M., Jaritz, M., Kavirayani, A., Garimella, M., Karlsson, MC., Busslinger, M. (2018) Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells. EMBO J.

Cai, Y., Hossain, MJ., Hériché, JK., Politi, AZ., Walther, N., Koch, B., Wachsmuth, M., Nijmeijer, B., Kueblbeck, M., Martinic-Kavur, M., Ladurner, R., Alexander, S., Peters, JM., Ellenberg, J. (2018) Experimental and computational framework for a dynamic protein atlas of human cell division. Nature. 561(7723):411-415

Catarino, RR., Stark, A. (2018) Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation. Genes Dev. 32(3-4):202-223

Corsini, NS., Peer, AM., Moeseneder, P., Roiuk, M., Burkard, TR., Theussl, HC., Moll, I., Knoblich, JA. (2018) Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation. Cell Stem Cell. 22(4):543-558.e12

Cronin, SJF., Seehus, C., Weidinger, A., Talbot, S., Reissig, S., Seifert, M., Pierson, Y., McNeill, E., Longhi, MS., Turnes, BL., Kreslavsky, T., Kogler, M., Hoffmann, D., Ticevic, M., da Luz Scheffer, D., Tortola, L., Cikes, D., Jais, A., Rangachari, M., Rao, S., Paolino, M., Novatchkova, M., Aichinger, M., Barrett, L., Latremoliere, A., Wirnsberger, G., Lametschwandtner, G., Busslinger, M., Zicha, S., Latini, A., Robson, SC., Waisman, A., Andrews, N., Costigan, M., Channon, KM., Weiss, G., Kozlov, AV., Tebbe, M., Johnsson, K., Woolf, CJ., Penninger, JM. (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature.

Doblmann, J., Dusberger, F., Imre, R., Hudecz, O., Stanek, F., Mechtler, K., Dürnberger, G. (2018) apQuant: Accurate Label-Free Quantification by Quality Filtering. J Proteome Res.

Dorfer, V., Maltsev, S., Winkler, S., Mechtler, K. (2018) CharmeRT: Boosting peptide identifications by chimeric spectra identification and retention time prediction. J Proteome Res.

Dorl, S., Winkler, S., Mechtler, K., Dorfer, V. (2018) PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search. J Proteome Res. 17(1):290-295

Ebner, P., Poetsch, I., Deszcz, L., Hoffmann, T., Zuber, J., Ikeda, F. (2018) The IAP family member BRUCE regulates autophagosome-lysosome fusion. Nat Commun. 9(1):599

Engels, S., Treiber, CD., Salzer, MC., Michalik, A., Ushakova, L., Keays, DA., Mouritsen, H., Heyers, D. (2018) Lidocaine is a nocebo treatment for trigeminally mediated magnetic orientation in birds. J R Soc Interface. 15(145)

Fei, JF., Lou, WP., Knapp, D., Murawala, P., Gerber, T., Taniguchi, Y., Nowoshilow, S., Khattak, S., Tanaka, EM. (2018) Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum). Nat Protoc. 13(12):2908-2943

Fitz, J., Neumann, T., Pavri, R. (2018) Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation. EMBO J. 37(8)

Fujimura, N., Kuzelova, A., Ebert, A., Strnad, H., Lachova, J., Machon, O., Busslinger, M., Kozmik, Z. (2018) Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation. Dev Biol. 433(1):47-60

Ganglberger, F., Kaczanowska, J., Penninger, JM., Hess, A., Bühler, K., Haubensak, W. (2018) Predicting functional neuroanatomical maps from fusing brain networks with genetic information. Neuroimage. 170:113-120

Gerber, T., Murawala, P., Knapp, D., Masselink, W., Schuez, M., Hermann, S., Gac-Santel, M., Nowoshilow, S., Kageyama, J., Khattak, S., Currie, JD., Camp, JG., Tanaka, EM., Treutlein, B. (2018) Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration. Science. 362(6413)

Gerlach, D., Tontsch-Grunt, U., Baum, A., Popow, J., Scharn, D., Hofmann, MH., Engelhardt, H., Kaya, O., Beck, J., Schweifer, N., Gerstberger, T., Zuber, J., Savarese, F., Kraut, N. (2018) The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML. Oncogene. 37(20):2687-2701

Griessner, J., Pasieka, M., Böhm, V., Grössl, F., Kaczanowska, J., Pliota, P., Kargl, D., Werner, B., Kaouane, N., Strobelt, S., Kreitz, S., Hess, A., Haubensak, W. (2018) Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect. Mol Psychiatry.

Groessl, F., Munsch, T., Meis, S., Griessner, J., Kaczanowska, J., Pliota, P., Kargl, D., Badurek, S., Kraitsy, K., Rassoulpour, A., Zuber, J., Lessmann, V., Haubensak, W. (2018) Dorsal tegmental dopamine neurons gate associative learning of fear. Nat Neurosci. 21(7):952-962

Gstrein, T., Edwards, A., Přistoupilová, A., Leca, I., Breuss, M., Pilat-Carotta, S., Hansen, AH., Tripathy, R., Traunbauer, AK., Hochstoeger, T., Rosoklija, G., Repic, M., Landler, L., Stránecký, V., Dürnberger, G., Keane, TM., Zuber, J., Adams, DJ., Flint, J., Honzik, T., Gut, M., Beltran, S., Mechtler, K., Sherr, E., Kmoch, S., Gut, I., Keays, DA. (2018) Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 21(2):207-217

Gstrein, T., Edwards, A., Přistoupilová, A., Leca, I., Breuss, M., Pilat-Carotta, S., Hansen, AH., Tripathy, R., Traunbauer, AK., Hochstoeger, T., Rosoklija, G., Repic, M., Landler, L., Stránecký, V., Dürnberger, G., Keane, TM., Zuber, J., Adams, DJ., Flint, J., Honzik, T., Gut, M., Beltran, S., Mechtler, K., Sherr, E., Kmoch, S., Gut, I., Keays, DA. (2018) Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci.

Haas, L., Wiesner, T., Obenauf, AC. (2018) A new era of proactive melanoma therapy: hit hard, hit early. Br J Dermatol. 178(4):817-820

Haberle, V., Stark, A. (2018) Eukaryotic core promoters and the functional basis of transcription initiation. Nat Rev Mol Cell Biol.

Haselbach, D., Komarov, I., Agafonov, DE., Hartmuth, K., Graf, B., Dybkov, O., Urlaub, H., Kastner, B., Lührmann, R., Stark, H. (2018) Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex. Cell. 172(3):454-464.e11

Hellerschmied, D., Roessler, M., Lehner, A., Gazda, L., Stejskal, K., Imre, R., Mechtler, K., Dammermann, A., Clausen, T. (2018) UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins. Nat Commun. 9(1):484

Herberg, S., Gert, KR., Schleiffer, A., Pauli, A. (2018) The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization. Science. 361(6406):1029-1033

Holt, C., Campbell, M., Keays, DA., Edelman, N., Kapusta, A., Maclary, E., T Domyan, E., Suh, A., Warren, WC., Yandell, M., Gilbert, MTP., Shapiro, MD. (2018) Improved Genome Assembly and Annotation for the Rock Pigeon (Columba livia). G3 (Bethesda). 8(5):1391-1398

Ivanov, MP., Ladurner, R., Poser, I., Beveridge, R., Rampler, E., Hudecz, O., Novatchkova, M., Hériché, JK., Wutz, G., van der Lelij, P., Kreidl, E., Hutchins, JR., Axelsson-Ekker, H., Ellenberg, J., Hyman, AA., Mechtler, K., Peters, JM. (2018) The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion. EMBO J. 37(15)

Kaplan, HS., Nichols, ALA., Zimmer, M. (2018) Sensorimotor integration in Caenorhabditis elegans: a reappraisal towards dynamic and distributed computations. Philos Trans R Soc Lond B Biol Sci. 373(1758)

Kaplan, HS., Zimmer, M. (2018) Sensorimotor Integration for Decision Making: How the Worm Steers. Neuron. 97(2):258-260

Kreslavsky, T., Wong, JB., Fischer, M., Skok, JA., Busslinger, M. (2018) Control of B-1a cell development by instructive BCR signaling. Curr Opin Immunol. 51:24-31

Landler, L., Keays, DA. (2018) Cryptochrome: The magnetosensor with a sinister side? PLoS Biol. 16(10):e3000018

Landler, L., Nimpf, S., Hochstoeger, T., Nordmann, GC., Papadaki-Anastasopoulou, A., Keays, DA. (2018) Comment on "Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans". Elife. 7

Malkemper, EP., Mason, MJ., Kagerbauer, D., Nimpf, S., Keays, DA. (2018) Ectopic otoconial formation in the lagena of the pigeon inner ear. Biol Open. 7(8)

Matsushima, W., Herzog, VA., Neumann, T., Gapp, K., Zuber, J., Ameres, SL., Miska, EA. (2018) SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting. Development. 145(13)

Medelnik, JP., Roensch, K., Okawa, S., Del Sol, A., Chara, O., Mchedlishvili, L., Tanaka, EM. (2018) Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells. Stem Cell Reports. 10(6):1751-1765

Milanovic, M., Fan, DNY., Belenki, D., Däbritz, JHM., Zhao, Z., Yu, Y., Dörr, JR., Dimitrova, L., Lenze, D., Monteiro Barbosa, IA., Mendoza-Parra, MA., Kanashova, T., Metzner, M., Pardon, K., Reimann, M., Trumpp, A., Dörken, B., Zuber, J., Gronemeyer, H., Hummel, M., Dittmar, G., Lee, S., Schmitt, CA. (2018) Senescence-associated reprogramming promotes cancer stemness. Nature. 553(7686):96-100

Mueller, N., Wicklein, D., Eisenwort, G., Jawhar, M., Berger, D., Stefanzl, G., Greiner, G., Boehm, A., Kornauth, C., Muellauer, L., Sehner, S., Hoermann, G., Sperr, WR., Staber, PB., Jaeger, U., Zuber, J., Arock, M., Schumacher, U., Reiter, A., Valent, P. (2018) CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis. Blood.

Muerdter, F., Boryń, ŁM., Woodfin, AR., Neumayr, C., Rath, M., Zabidi, MA., Pagani, M., Haberle, V., Kazmar, T., Catarino, RR., Schernhuber, K., Arnold, CD., Stark, A. (2018) Resolving systematic errors in widely used enhancer activity assays in human cells. Nat Methods. 15(2):141-149

Muhar, M., Ebert, A., Neumann, T., Umkehrer, C., Jude, J., Wieshofer, C., Rescheneder, P., Lipp, JJ., Herzog, VA., Reichholf, B., Cisneros, DA., Hoffmann, T., Schlapansky, MF., Bhat, P., von Haeseler, A., Köcher, T., Obenauf, AC., Popow, J., Ameres, SL., Zuber, J. (2018) SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 360(6390):800-805

Nowoshilow, S., Schloissnig, S., Fei, JF., Dahl, A., Pang, AWC., Pippel, M., Winkler, S., Hastie, AR., Young, G., Roscito, JG., Falcon, F., Knapp, D., Powell, S., Cruz, A., Cao, H., Habermann, B., Hiller, M., Tanaka, EM., Myers, EW. (2018) The axolotl genome and the evolution of key tissue formation regulators. Nature. 554(7690):50-55

Nowoshilow, S., Schloissnig, S., Fei, JF., Dahl, A., Pang, AWC., Pippel, M., Winkler, S., Hastie, AR., Young, G., Roscito, JG., Falcon, F., Knapp, D., Powell, S., Cruz, A., Cao, H., Habermann, B., Hiller, M., Tanaka, EM., Myers, EW. (2018) Author Correction: The axolotl genome and the evolution of key tissue formation regulators. Nature. 559(7712):E2

Oliveira, CR., Lemaitre, R., Murawala, P., Tazaki, A., Drechsel, DN., Tanaka, EM. (2018) Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration. Dev Biol. 433(2):262-275

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Nat Protoc. 13(3):478-494

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Reply to 'Defining distance restraints in HADDOCK'. Nat Protoc. 13(7):1503-1505

Orbán-Németh, Z., Beveridge, R., Hollenstein, DM., Rampler, E., Stranzl, T., Hudecz, O., Doblmann, J., Schlögelhofer, P., Mechtler, K. (2018) Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Nat Protoc.

Osman, K., Yang, J., Roitinger, E., Lambing, C., Heckmann, S., Howell, E., Cuacos, M., Imre, R., Dürnberger, G., Mechtler, K., Armstrong, S., Franklin, FCH. (2018) Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis. Plant J. 93(1):17-33

Peter, B., Bibi, S., Eisenwort, G., Wingelhofer, B., Berger, D., Stefanzl, G., Blatt, K., Herrmann, H., Hadzijusufovic, E., Hoermann, G., Hoffmann, T., Schwaab, J., Jawhar, M., Willmann, M., Sperr, WR., Zuber, J., Sotlar, K., Horny, HP., Moriggl, R., Reiter, A., Arock, M., Valent, P. (2018) Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells. Leukemia. 32(4):1016-1022

Plaschka, C., Lin, PC., Charenton, C., Nagai, K. (2018) Prespliceosome structure provides insights into spliceosome assembly and regulation. Nature. 559(7714):419-422

Pliota, P., Böhm, V., Grössl, F., Griessner, J., Valenti, O., Kraitsy, K., Kaczanowska, J., Pasieka, M., Lendl, T., Deussing, JM., Haubensak, W. (2018) Stress peptides sensitize fear circuitry to promote passive coping. Mol Psychiatry.

Rojo Romanos, T., Ng, L., Pocock, R. (2018) Behavioral Assays to Study Oxygen and Carbon Dioxide Sensing in Caenorhabditis elegans. Bio Protoc. 8(1)

Rouse, T., Aubry, G., Cho, Y., Zimmer, M., Lu, H. (2018) A programmable platform for sub-second multichemical dynamic stimulation and neuronal functional imaging in C. elegans. Lab Chip. 18(3):505-513

Sanyal, S., Molnarova, L., Richterova, J., Huraiova, B., Benko, Z., Polakova, S., Cipakova, I., Sevcovicova, A., Gaplovska-Kysela, K., Mechtler, K., Cipak, L., Gregan, J. (2018) Mutations that prevent methylation of cohesin render sensitivity to DNA damage. J Cell Sci.

Seehawer, M., Heinzmann, F., D'Artista, L., Harbig, J., Roux, PF., Hoenicke, L., Dang, H., Klotz, S., Robinson, L., Doré, G., Rozenblum, N., Kang, TW., Chawla, R., Buch, T., Vucur, M., Roth, M., Zuber, J., Luedde, T., Sipos, B., Longerich, T., Heikenwälder, M., Wang, XW., Bischof, O., Zender, L. (2018) Necroptosis microenvironment directs lineage commitment in liver cancer. Nature. 562(7725):69-75

Silva, MCC., Wutz, G., Tachibana, K., Peters, JM. (2018) Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy. Methods Cell Biol. 144:287-305

Skocek, O., Nöbauer, T., Weilguny, L., Martínez Traub, F., Xia, CN., Molodtsov, MI., Grama, A., Yamagata, M., Aharoni, D., Cox, DD., Golshani, P., Vaziri, A. (2018) High-speed volumetric imaging of neuronal activity in freely moving rodents. Nat Methods.

Skocek, O., Nöbauer, T., Weilguny, L., Traub, FM., Xia, CN., Molodtsov, MI., Grama, A., Yamagata, M., Aharoni, D., Cox, DD., Golshani, P., Vaziri, A. (2018) Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents. Nat Methods. 15(6):469

Skora, S., Mende, F., Zimmer, M. (2018) Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans. Cell Rep. 22(4):953-966

Skucha, A., Ebner, J., Schmöllerl, J., Roth, M., Eder, T., César-Razquin, A., Stukalov, A., Vittori, S., Muhar, M., Lu, B., Aichinger, M., Jude, J., Müller, AC., Győrffy, B., Vakoc, CR., Valent, P., Bennett, KL., Zuber, J., Superti-Furga, G., Grebien, F. (2018) MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity. Nat Commun. 9(1):1983

Smakowska-Luzan, E., Mott, GA., Parys, K., Stegmann, M., Howton, TC., Layeghifard, M., Neuhold, J., Lehner, A., Kong, J., Grünwald, K., Weinberger, N., Satbhai, SB., Mayer, D., Busch, W., Madalinski, M., Stolt-Bergner, P., Provart, NJ., Mukhtar, MS., Zipfel, C., Desveaux, D., Guttman, DS., Belkhadir, Y. (2018) An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Nature. 553(7688):342-346

Stadlmann, J., Hoi, DM., Taubenschmid, J., Mechtler, K., Penninger, JM. (2018) Analysis of PNGase F-resistant N-glycopeptides using SugarQb for Proteome Discoverer 2.1 reveals cryptic substrate specificities. Proteomics. :e1700436

Stanyte, R., Nuebler, J., Blaukopf, C., Hoefler, R., Stocsits, R., Peters, JM., Gerlich, DW. (2018) Dynamics of sister chromatid resolution during cell cycle progression. J Cell Biol.

Szappanos, D., Tschismarov, R., Perlot, T., Westermayer, S., Fischer, K., Platanitis, E., Kallinger, F., Novatchkova, M., Lassnig, C., Müller, M., Sexl, V., Bennett, KL., Foong-Sobis, M., Penninger, JM., Decker, T. (2018) The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity. PLoS Pathog. 14(11):e1007397

Tanaka, EM. (2018) Regenerating tissues. Science. 360(6387):374-375

Tripathy, R., Leca, I., van Dijk, T., Weiss, J., van Bon, BW., Sergaki, MC., Gstrein, T., Breuss, M., Tian, G., Bahi-Buisson, N., Paciorkowski, AR., Pagnamenta, AT., Wenninger-Weinzierl, A., Martinez-Reza, MF., Landler, L., Lise, S., Taylor, JC., Terrone, G., Vitiello, G., Del Giudice, E., Brunetti-Pierri, N., D'Amico, A., Reymond, A., Voisin, N., Bernstein, JA., Farrelly, E., Kini, U., Leonard, TA., Valence, S., Burglen, L., Armstrong, L., Hiatt, SM., Cooper, GM., Aldinger, KA., Dobyns, WB., Mirzaa, G., Pierson, TM., Baas, F., Chelly, J., Cowan, NJ., Keays, DA. (2018) Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 100(6):1354-1368.e5

Watson, ER., Brown, NG., Peters, JM., Stark, H., Schulman, BA. (2018) Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. Trends Cell Biol.

Weisenburger, S., Vaziri, A. (2018) A Guide to Emerging Technologies for Large-Scale and Whole-Brain Optical Imaging of Neuronal Activity. Annu Rev Neurosci.

Weissmann, F., Peters, JM. (2018) Expressing Multi-subunit Complexes Using biGBac. Methods Mol Biol. 1764:329-343

Yang, T., Cui, H., Wen, M., Zuber, J., Kogan, SC., Wei, G. (2018) TCEA1 regulates the proliferative potential of mouse myeloid cells. Exp Cell Res.

2017

Aarts, M., Georgilis, A., Beniazza, M., Beolchi, P., Banito, A., Carroll, T., Kulisic, M., Kaemena, DF., Dharmalingam, G., Martin, N., Reik, W., Zuber, J., Kaji, K., Chandra, T., Gil, J. (2017) Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence. Genes Dev. 31(20):2085-2098

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Haberle, V., Stark, A. (2015) Coordinating the human looks. Cell. 163(1):24-6

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Kulinski, TM., Casari, MR., Guenzl, PM., Wenzel, D., Andergassen, D., Hladik, A., Datlinger, P., Farlik, M., Theussl, HC., Penninger, JM., Knapp, S., Bock, C., Barlow, DP., Hudson, QJ. (2015) Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern. Dev Biol. 402(2):291-305

Lambing, C., Osman, K., Nuntasoontorn, K., West, A., Higgins, JD., Copenhaver, GP., Yang, J., Armstrong, SJ., Mechtler, K., Roitinger, E., Franklin, FC. (2015) Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers. PLoS Genet. 11(7):e1005372

Loewenstein, Y., Yanover, U., Rumpel, S. (2015) Predicting the Dynamics of Network Connectivity in the Neocortex. J Neurosci. 35(36):12535-44

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2012

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Dal Santo, S., Stampfl, H., Krasensky, J., Kempa, S., Gibon, Y., Petutschnig, E., Rozhon, W., Heuck, A., Clausen, T., Jonak, C. (2012) Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis. Plant Cell. 24(8):3380-92

Demczuk, A., Gauthier, MG., Veras, I., Kosiyatrakul, S., Schildkraut, CL., Busslinger, M., Bechhoefer, J., Norio, P. (2012) Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment. PLoS Biol. 10(7):e1001360

Diogo, R., Tanaka, EM. (2012) Anatomy of the pectoral and forelimb muscles of wildtype and green fluorescent protein-transgenic axolotls and comparison with other tetrapods including humans: a basis for regenerative, evolutionary and developmental studies. J Anat. 221(6):622-35

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Hnisz, D., Bardet, AF., Nobile, CJ., Petryshyn, A., Glaser, W., Schöck, U., Stark, A., Kuchler, K. (2012) A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis. PLoS Genet. 8(12):e1003118

Hoyler, T., Klose, CS., Souabni, A., Turqueti-Neves, A., Pfeifer, D., Rawlins, EL., Voehringer, D., Busslinger, M., Diefenbach, A. (2012) The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells. Immunity. 37(4):634-48

Jafari, S., Alkhori, L., Schleiffer, A., Brochtrup, A., Hummel, T., Alenius, M. (2012) Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression. PLoS Biol. 10(3):e1001280

Keleman, K., Vrontou, E., Krüttner, S., Yu, JY., Kurtovic-Kozaric, A., Dickson, BJ. (2012) Dopamine neurons modulate pheromone responses in Drosophila courtship learning. Nature. 489(7414):145-9

Knapp, D., Tanaka, EM. (2012) Regeneration and reprogramming. Curr Opin Genet Dev. 22(5):485-93

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Krüttner, S., Stepien, B., Noordermeer, JN., Mommaas, MA., Mechtler, K., Dickson, BJ., Keleman, K. (2012) Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain. Neuron. 76(2):383-95

Kvon, EZ., Stampfel, G., Yáñez-Cuna, JO., Dickson, BJ., Stark, A. (2012) HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature. Genes Dev. 26(9):908-13

Lai, JS., Lo, SJ., Dickson, BJ., Chiang, AS. (2012) Auditory circuit in the Drosophila brain. Proc Natl Acad Sci U S A. 109(7):2607-12

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Malet, H., Canellas, F., Sawa, J., Yan, J., Thalassinos, K., Ehrmann, M., Clausen, T., Saibil, HR. (2012) Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nat Struct Mol Biol. 19(2):152-7

Mattarollo, SR., West, AC., Steegh, K., Duret, H., Paget, C., Martin, B., Matthews, GM., Shortt, J., Chesi, M., Bergsagel, PL., Bots, M., Zuber, J., Lowe, SW., Johnstone, RW., Smyth, MJ. (2012) NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma. Blood. 120(15):3019-29

McHedlishvili, L., Mazurov, V., Grassme, KS., Goehler, K., Robl, B., Tazaki, A., Roensch, K., Duemmler, A., Tanaka, EM. (2012) Reconstitution of the central and peripheral nervous system during salamander tail regeneration. Proc Natl Acad Sci U S A. 109(34):E2258-66

McHedlishvili, L., Mazurov, V., Tanaka, EM. (2012) Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres. Methods Mol Biol. 916:197-202

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Novatchkova, M., Tomanov, K., Hofmann, K., Stuible, HP., Bachmair, A. (2012) Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison. New Phytol. 195(1):23-31

Pagnamenta, AT., Lise, S., Harrison, V., Stewart, H., Jayawant, S., Quaghebeur, G., Deng, AT., Murphy, VE., Sadighi Akha, E., Rimmer, A., Mathieson, I., Knight, SJ., Kini, U., Taylor, JC., Keays, DA. (2012) Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies. J Hum Genet. 57(1):70-2

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Peter, M., Scheuch, H., Burkard, TR., Tinter, J., Wernle, T., Rumpel, S. (2012) Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds. Genes Brain Behav. 11(3):314-24

Peters, JM. (2012) The many functions of cohesin--different rings to rule them all? EMBO J. 31(9):2061-3

Peters, JM., Nishiyama, T. (2012) Sister chromatid cohesion. Cold Spring Harb Perspect Biol. 4(11)

Pichler, P., Mazanek, M., Dusberger, F., Weilnböck, L., Huber, CG., Stingl, C., Luider, TM., Straube, WL., Köcher, T., Mechtler, K. (2012) SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments. J Proteome Res. 11(11):5540-7

Plath, K., Srivastava, D., Alvarez-Buylla, A., Tanaka, EM., Kriegstein, AR. (2012) Stem cells in the land of the rising sun: ISSCR 2012. Cell Stem Cell. 11(5):607-14

Popow, J., Schleiffer, A., Martinez, J. (2012) Diversity and roles of (t)RNA ligases. Cell Mol Life Sci. 69(16):2657-70

Protze, S., Khattak, S., Poulet, C., Lindemann, D., Tanaka, EM., Ravens, U. (2012) A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells. J Mol Cell Cardiol. 53(3):323-32

Revilla-I-Domingo, R., Bilic, I., Vilagos, B., Tagoh, H., Ebert, A., Tamir, IM., Smeenk, L., Trupke, J., Sommer, A., Jaritz, M., Busslinger, M. (2012) The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis. EMBO J. 31(14):3130-46

Schleiffer, A., Maier, M., Litos, G., Lampert, F., Hornung, P., Mechtler, K., Westermann, S. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol. 14(6):604-13

Tanaka, EM. (2012) Regenerative biology: Skin, heal thyself. Nature. 489(7417):508-10

Tapia, N., Reinhardt, P., Duemmler, A., Wu, G., Araúzo-Bravo, MJ., Esch, D., Greber, B., Cojocaru, V., Rascon, CA., Tazaki, A., Kump, K., Voss, R., Tanaka, EM., Schöler, HR. (2012) Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nat Commun. 3:1279

Tennstaedt, A., Pöpsel, S., Truebestein, L., Hauske, P., Brockmann, A., Schmidt, N., Irle, I., Sacca, B., Niemeyer, CM., Brandt, R., Ksiezak-Reding, H., Tirniceriu, AL., Egensperger, R., Baldi, A., Dehmelt, L., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2012) Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates. J Biol Chem. 287(25):20931-41

Toda, H., Zhao, X., Dickson, BJ. (2012) The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior. Cell Rep. 1(6):599-607

Treiber, CD., Salzer, MC., Riegler, J., Edelman, N., Sugar, C., Breuss, M., Pichler, P., Cadiou, H., Saunders, M., Lythgoe, M., Shaw, J., Keays, DA. (2012) Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons. Nature. 484(7394):367-70

Uzunova, K., Dye, BT., Schutz, H., Ladurner, R., Petzold, G., Toyoda, Y., Jarvis, MA., Brown, NG., Poser, I., Novatchkova, M., Mechtler, K., Hyman, AA., Stark, H., Schulman, BA., Peters, JM. (2012) APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex. Nat Struct Mol Biol. 19(11):1116-23

Valent, P., Bonnet, D., De Maria, R., Lapidot, T., Copland, M., Melo, JV., Chomienne, C., Ishikawa, F., Schuringa, JJ., Stassi, G., Huntly, B., Herrmann, H., Soulier, J., Roesch, A., Schuurhuis, GJ., Wöhrer, S., Arock, M., Zuber, J., Cerny-Reiterer, S., Johnsen, HE., Andreeff, M., Eaves, C. (2012) Cancer stem cell definitions and terminology: the devil is in the details. Nat Rev Cancer. 12(11):767-75

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Vaziri, A., Emiliani, V. (2012) Reshaping the optical dimension in optogenetics. Curr Opin Neurobiol. 22(1):128-37

Vilagos, B., Hoffmann, M., Souabni, A., Sun, Q., Werner, B., Medvedovic, J., Bilic, I., Minnich, M., Axelsson, E., Jaritz, M., Busslinger, M. (2012) Essential role of EBF1 in the generation and function of distinct mature B cell types. J Exp Med. 209(4):775-92

Vinzenz, M., Nemethova, M., Schur, F., Mueller, J., Narita, A., Urban, E., Winkler, C., Schmeiser, C., Koestler, SA., Rottner, K., Resch, GP., Maeda, Y., Small, JV. (2012) Actin branching in the initiation and maintenance of lamellipodia. J Cell Sci. 125(Pt 11):2775-85

Whelan, G., Kreidl, E., Peters, JM., Eichele, G. (2012) The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions. Nucleus. 3(4):330-4

Whelan, G., Kreidl, E., Wutz, G., Egner, A., Peters, JM., Eichele, G. (2012) Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J. 31(1):71-82

Wray, J., Hartmann, C. (2012) WNTing embryonic stem cells. Trends Cell Biol. 22(3):159-68

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, AR., Simon, J., Zhang, J., Luo, W., Hicks, J., Zender, L., Wang, XW., Powers, S., Wigler, M., Lowe, SW. (2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proc Natl Acad Sci U S A. 109(21):8212-7

Yáñez-Cuna, JO., Dinh, HQ., Kvon, EZ., Shlyueva, D., Stark, A. (2012) Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding. Genome Res. 22(10):2018-30

Zimniak, T., Fitz, V., Zhou, H., Lampert, F., Opravil, S., Mechtler, K., Stolt-Bergner, P., Westermann, S. (2012) Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation. Curr Biol. 22(9):787-93

2011

Agrelo R. (2011) X Inactivation and Progenitor Cancer Cells Cancers. 3(2):2169-2175

Alexander, J., Lim, D., Joughin, BA., Hegemann, B., Hutchins, JR., Ehrenberger, T., Ivins, F., Sessa, F., Hudecz, O., Nigg, EA., Fry, AM., Musacchio, A., Stukenberg, PT., Mechtler, K., Peters, JM., Smerdon, SJ., Yaffe, MB. (2011) Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling. Sci Signal. 4(179):ra42

Bakiri, L., Reschke, MO., Gefroh, HA., Idarraga, MH., Polzer, K., Zenz, R., Schett, G., Wagner, EF. (2011) Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis. Oncogene. 30(13):1506-17

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Böhmdorfer, G., Schleiffer, A., Brunmeir, R., Ferscha, S., Nizhynska, V., Kozák, J., Angelis, KJ., Kreil, DP., Schweizer, D. (2011) GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis. Plant J. 67(3):420-33

Breitwieser, FP., Müller, A., Dayon, L., Köcher, T., Hainard, A., Pichler, P., Schmidt-Erfurth, U., Superti-Furga, G., Sanchez, JC., Mechtler, K., Bennett, KL., Colinge, J. (2011) General statistical modeling of data from protein relative expression isobaric tags. J Proteome Res. 10(6):2758-66

Buschhorn, BA., Petzold, G., Galova, M., Dube, P., Kraft, C., Herzog, F., Stark, H., Peters, JM. (2011) Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1. Nat Struct Mol Biol. 18(1):6-13

Campbell, LJ., Suárez-Castillo, EC., Ortiz-Zuazaga, H., Knapp, D., Tanaka, EM., Crews, CM. (2011) Gene expression profile of the regeneration epithelium during axolotl limb regeneration. Dev Dyn. 240(7):1826-40

Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) HTRA proteases: regulated proteolysis in protein quality control. Nat Rev Mol Cell Biol. 12(3):152-62

Cretney, E., Xin, A., Shi, W., Minnich, M., Masson, F., Miasari, M., Belz, GT., Smyth, GK., Busslinger, M., Nutt, SL., Kallies, A. (2011) The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells. Nat Immunol. 12(4):304-11

Ebert, A., McManus, S., Tagoh, H., Medvedovic, J., Salvagiotto, G., Novatchkova, M., Tamir, I., Sommer, A., Jaritz, M., Busslinger, M. (2011) The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells. Immunity. 34(2):175-87

Edwards, A., Treiber, CD., Breuss, M., Pidsley, R., Huang, GJ., Cleak, J., Oliver, PL., Flint, J., Keays, DA. (2011) Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse. Neuroscience. 195:191-200

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Elsayad, K., Suplata, M., Heinze, KG. (2011) Using MATLAB to Achieve Nanoscale Optical Sectioning in the Vicinity of Metamaterial Substrates by Simulating Emitter-Substrate Interactions Engineering Education and Research Using MATLAB.

Fellmann, C., Zuber, J., McJunkin, K., Chang, K., Malone, CD., Dickins, RA., Xu, Q., Hengartner, MO., Elledge, SJ., Hannon, GJ., Lowe, SW. (2011) Functional identification of optimized RNAi triggers using a massively parallel sensor assay. Mol Cell. 41(6):733-46

Fischer, H., Szabo, S., Scherz, J., Jaeger, K., Rossiter, H., Buchberger, M., Ghannadan, M., Hermann, M., Theussl, HC., Tobin, DJ., Wagner, EF., Tschachler, E., Eckhart, L. (2011) Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails. J Invest Dermatol. 131(6):1208-15

Ganim, Z., Tokmakoff, A., Vaziri, A. (2011) Vibrational excitons in ionophores: experimental probes for quantum coherence-assisted ion transport and selectivity in ion channels New J. Phys.. 13

Gimferrer, I., Hu, T., Simmons, A., Wang, C., Souabni, A., Busslinger, M., Bender, TP., Hernandez-Hoyos, G., Alberola-Ila, J. (2011) Regulation of GATA-3 expression during CD4 lineage differentiation. J Immunol. 186(7):3892-8

Grebien, F., Hantschel, O., Wojcik, J., Kaupe, I., Kovacic, B., Wyrzucki, AM., Gish, GD., Cerny-Reiterer, S., Koide, A., Beug, H., Pawson, T., Valent, P., Koide, S., Superti-Furga, G. (2011) Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis. Cell. 147(2):306-19

Grosstessner-Hain, K., Hegemann, B., Novatchkova, M., Rameseder, J., Joughin, BA., Hudecz, O., Roitinger, E., Pichler, P., Kraut, N., Yaffe, MB., Peters, JM., Mechtler, K. (2011) Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome. Mol Cell Proteomics. 10(11):M111.008540

Guo, C., Yoon, HS., Franklin, A., Jain, S., Ebert, A., Cheng, HL., Hansen, E., Despo, O., Bossen, C., Vettermann, C., Bates, JG., Richards, N., Myers, D., Patel, H., Gallagher, M., Schlissel, MS., Murre, C., Busslinger, M., Giallourakis, CC., Alt, FW. (2011) CTCF-binding elements mediate control of V(D)J recombination. Nature. 477(7365):424-30

Häärä, O., Fujimori, S., Schmidt-Ullrich, R., Hartmann, C., Thesleff, I., Mikkola, ML. (2011) Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. Development. 138(13):2681-91

Hadjieconomou, D., Rotkopf, S., Alexandre, C., Bell, DM., Dickson, BJ., Salecker, I. (2011) Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. Nat Methods. 8(3):260-6

Handler, D., Olivieri, D., Novatchkova, M., Gruber, FS., Meixner, K., Mechtler, K., Stark, A., Sachidanandam, R., Brennecke, J. (2011) A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors. EMBO J. 30(19):3977-93

Hasanovic, A., Winkler, R., Resch, GP., Valenta, C. (2011) Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir. Eur J Pharm Biopharm. 79(1):76-81

He, Q., Bardet, AF., Patton, B., Purvis, J., Johnston, J., Paulson, A., Gogol, M., Stark, A., Zeitlinger, J. (2011) High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species. Nat Genet. 43(5):414-20

Hegemann, B., Hutchins, JR., Hudecz, O., Novatchkova, M., Rameseder, J., Sykora, MM., Liu, S., Mazanek, M., Lénárt, P., Hériché, JK., Poser, I., Kraut, N., Hyman, AA., Yaffe, MB., Mechtler, K., Peters, JM. (2011) Systematic phosphorylation analysis of human mitotic protein complexes. Sci Signal. 4(198):rs12

Heuck, A., Schleiffer, A., Clausen, T. (2011) Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins. J Mol Biol. 406(5):659-66

Hilgers, V., Perry, MW., Hendrix, D., Stark, A., Levine, M., Haley, B. (2011) Neural-specific elongation of 3' UTRs during Drosophila development. Proc Natl Acad Sci U S A. 108(38):15864-9

Holzmann, J., Fuchs, J., Pichler, P., Peters, JM., Mechtler, K. (2011) Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads. J Proteome Res. 10(2):780-9

Hornung, P., Maier, M., Alushin, GM., Lander, GC., Nogales, E., Westermann, S. (2011) Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex. J Mol Biol. 405(2):548-59

Huang, R., Jaritz, M., Guenzl, P., Vlatkovic, I., Sommer, A., Tamir, IM., Marks, H., Klampfl, T., Kralovics, R., Stunnenberg, HG., Barlow, DP., Pauler, FM. (2011) An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs. PLoS One. 6(11):e27288

Jászai, J., Fargeas, CA., Graupner, S., Tanaka, EM., Brand, M., Huttner, WB., Corbeil, D. (2011) Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species. PLoS One. 6(3):e17590

Khan, AG., Pickl-Herk, A., Gajdzik, L., Marlovits, TC., Fuchs, R., Blaas, D. (2011) Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin. Virology. 412(1):55-67

Kley, J., Schmidt, B., Boyanov, B., Stolt-Bergner, PC., Kirk, R., Ehrmann, M., Knopf, RR., Naveh, L., Adam, Z., Clausen, T. (2011) Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure. Nat Struct Mol Biol. 18(6):728-31

Köcher, T. (2011) Comment on 'Jobs for the boys'. EMBO Rep. 12(6):488

Köcher, T., Pichler, P., Mazanek, M., Swart, R., Mechtler, K. (2011) Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications. Anal Bioanal Chem. 400(8):2339-47

Köcher, T., Pichler, P., Swart, R., Mechtler, K. (2011) Quality control in LC-MS/MS. Proteomics. 11(6):1026-30

Köcher, T., Swart, R., Mechtler, K. (2011) Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides. Anal Chem. 83(7):2699-704

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Lampert, F., Westermann, S. (2011) A blueprint for kinetochores - new insights into the molecular mechanics of cell division. Nat Rev Mol Cell Biol. 12(7):407-12

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Loewenstein, Y., Kuras, A., Rumpel, S. (2011) Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo. J Neurosci. 31(26):9481-8

Lyashenko, N., Winter, M., Migliorini, D., Biechele, T., Moon, RT., Hartmann, C. (2011) Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation. Nat Cell Biol. 13(7):753-61

Malle, E., Zhou, H., Neuhold, J., Spitzenberger, B., Klepsch, F., Pollak, T., Bergner, O., Ecker, GF., Stolt-Bergner, PC. (2011) Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues. J Biol Chem. 286(26):23121-31

McManus, S., Ebert, A., Salvagiotto, G., Medvedovic, J., Sun, Q., Tamir, I., Jaritz, M., Tagoh, H., Busslinger, M. (2011) The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells. EMBO J. 30(12):2388-404

Mechtcheriakova, D., Sobanov, Y., Holtappels, G., Bajna, E., Svoboda, M., Jaritz, M., Bachert, C., Jensen-Jarolim, E. (2011) Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component. PLoS One. 6(10):e25611

Medvedovic, J., Ebert, A., Tagoh, H., Busslinger, M. (2011) Pax5: a master regulator of B cell development and leukemogenesis. Adv Immunol. 111:179-206

Merdanovic, M., Clausen, T., Kaiser, M., Huber, R., Ehrmann, M. (2011) Protein quality control in the bacterial periplasm. Annu Rev Microbiol. 65:149-68

Nacu, E., Tanaka, EM. (2011) Limb regeneration: a new development? Annu Rev Cell Dev Biol. 27:409-40

Neumüller, RA., Richter, C., Fischer, A., Novatchkova, M., Neumüller, KG., Knoblich, JA. (2011) Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Cell Stem Cell. 8(5):580-93

Ng, K., Daigle, N., Bancaud, A., Ohhata, T., Humphreys, P., Walker, R., Ellenberg, J., Wutz, A. (2011) A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells. Mol Biol Cell. 22(14):2634-45

Pappu, KS., Morey, M., Nern, A., Spitzweck, B., Dickson, BJ., Zipursky, SL. (2011) Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development. Proc Natl Acad Sci U S A. 108(18):7571-6

Pichler, P., Köcher, T., Holzmann, J., Möhring, T., Ammerer, G., Mechtler, K. (2011) Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell. Anal Chem. 83(4):1469-74

Popow, J., Englert, M., Weitzer, S., Schleiffer, A., Mierzwa, B., Mechtler, K., Trowitzsch, S., Will, CL., Lührmann, R., Söll, D., Martinez, J. (2011) HSPC117 is the essential subunit of a human tRNA splicing ligase complex. Science. 331(6018):760-4

Qin, H., Suzuki, K., Nakata, M., Chikuma, S., Izumi, N., Huong, le T., Maruya, M., Fagarasan, S., Busslinger, M., Honjo, T., Nagaoka, H. (2011) Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age. PLoS One. 6(12):e29141

Resch, GP., Brandstetter, M., Pickl-Herk, AM., Königsmaier, L., Wonesch, VI., Urban, E. (2011) Immersion freezing of biological specimens: rationale, principles, and instrumentation. Cold Spring Harb Protoc. 2011(7):778-82

Sampaio, JL., Gerl, MJ., Klose, C., Ejsing, CS., Beug, H., Simons, K., Shevchenko, A. (2011) Membrane lipidome of an epithelial cell line. Proc Natl Acad Sci U S A. 108(5):1903-7

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Schönbauer, C., Distler, J., Jährling, N., Radolf, M., Dodt, HU., Frasch, M., Schnorrer, F. (2011) Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects. Nature. 479(7373):406-9

Schraidt, O., Marlovits, TC. (2011) Three-dimensional model of Salmonella's needle complex at subnanometer resolution. Science. 331(6021):1192-5

Stöger-Pollach, M., Treiber, CD., Resch, GP., Keays, DA., Ennen, I. (2011) EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 42(5):456-60

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Tanaka, EM., Reddien, PW. (2011) The cellular basis for animal regeneration. Dev Cell. 21(1):172-85

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Truebestein, L., Tennstaedt, A., Mönig, T., Krojer, T., Canellas, F., Kaiser, M., Clausen, T., Ehrmann, M. (2011) Substrate-induced remodeling of the active site regulates human HTRA1 activity. Nat Struct Mol Biol. 18(3):386-8

von Philipsborn, AC., Liu, T., Yu, JY., Masser, C., Bidaye, SS., Dickson, BJ. (2011) Neuronal control of Drosophila courtship song. Neuron. 69(3):509-22

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2010

Agrelo, R., Wutz, A. (2010) ConteXt of change--X inactivation and disease. EMBO Mol Med. 2(1):6-15

Agrelo, R., Wutz, A. (2010) X inactivation and disease. Semin Cell Dev Biol. 21(2):194-200

Alpert, AJ., Petritis, K., Kangas, L., Smith, RD., Mechtler, K., Mitulović, G., Mohammed, S., Heck, AJ. (2010) Peptide orientation affects selectivity in ion-exchange chromatography. Anal Chem. 82(12):5253-9

Antos, CL., Tanaka, EM. (2010) Vertebrates that regenerate as models for guiding stem cels. Adv Exp Med Biol. 695:184-214

Baudrimont, A., Penkner, A., Woglar, A., Machacek, T., Wegrostek, C., Gloggnitzer, J., Fridkin, A., Klein, F., Gruenbaum, Y., Pasierbek, P., Jantsch, V. (2010) Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans. PLoS Genet. 6(11):e1001219

Baumann, CL., Aspalter, IM., Sharif, O., Pichlmair, A., Blüml, S., Grebien, F., Bruckner, M., Pasierbek, P., Aumayr, K., Planyavsky, M., Bennett, KL., Colinge, J., Knapp, S., Superti-Furga, G. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med. 207(12):2689-701

Berg, DA., Kirkham, M., Beljajeva, A., Knapp, D., Habermann, B., Ryge, J., Tanaka, EM., Simon, A. (2010) Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain. Development. 137(24):4127-34

Bouchard, M., de Caprona, D., Busslinger, M., Xu, P., Fritzsch, B. (2010) Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation. BMC Dev Biol. 10:89

Braglia, P., Heindl, K., Schleiffer, A., Martinez, J., Proudfoot, NJ. (2010) Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I. EMBO Rep. 11(10):758-64

Braun, A., Breuss, M., Salzer, MC., Flint, J., Cowan, NJ., Keays, DA. (2010) Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 86(5):819-22; author reply 822-3

Cachero, S., Ostrovsky, AD., Yu, JY., Dickson, BJ., Jefferis, GS. (2010) Sexual dimorphism in the fly brain. Curr Biol. 20(18):1589-601

Csiszar, A., Vogelsang, E., Beug, H., Leptin, M. (2010) A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol. 30(8):2017-27

Dickson, BJ., Zou, Y. (2010) Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol. 2(8):a002055

El-Kasaby, A., Just, H., Malle, E., Stolt-Bergner, PC., Sitte, HH., Freissmuth, M., Kudlacek, O. (2010) Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter. J Biol Chem. 285(50):39201-10

Elsayad, K., Heinze, KG. (2010) Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks Physical Review A. 81(5)

Elsayad, K., Heinze, KG. (2010) Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films Proc. SPIE. 7757:77573L

Elsayad, K., Urich, A., Unterrainer, K., Heinze, KG. (2010) Fast near-field imaging of spectrally broad sources using layered metallic structures Proc. SPIE. 7757:77573M

Eskeland, R., Leeb, M., Grimes, GR., Kress, C., Boyle, S., Sproul, D., Gilbert, N., Fan, Y., Skoultchi, AI., Wutz, A., Bickmore, WA. (2010) Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination. Mol Cell. 38(3):452-64

Feng, W., Yonezawa, M., Ye, J., Jenuwein, T., Grummt, I. (2010) PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation. Nat Struct Mol Biol. 17(4):445-50

Friedbichler, K., Kerenyi, MA., Kovacic, B., Li, G., Hoelbl, A., Yahiaoui, S., Sexl, V., Müllner, EW., Fajmann, S., Cerny-Reiterer, S., Valent, P., Beug, H., Gouilleux, F., Bunting, KD., Moriggl, R. (2010) Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood. 116(9):1548-58

Fuchs, A., Inthal, A., Herrmann, D., Cheng, S., Nakatomi, M., Peters, H., Neubüser, A. (2010) Regulation of Tbx22 during facial and palatal development. Dev Dyn. 239(11):2860-74

Fujimori, S., Novak, H., Weissenböck, M., Jussila, M., Gonçalves, A., Zeller, R., Galloway, J., Thesleff, I., Hartmann, C. (2010) Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4. Dev Biol. 348(1):97-106

Galkin, VE., Schmied, WH., Schraidt, O., Marlovits, TC., Egelman, EH. (2010) The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system. J Mol Biol. 396(5):1392-7

Gin, E., Tanaka, EM., Brusch, L. (2010) A model for cyst lumen expansion and size regulation via fluid secretion. J Theor Biol. 264(3):1077-88

Grausenburger, R., Bilic, I., Boucheron, N., Zupkovitz, G., El-Housseiny, L., Tschismarov, R., Zhang, Y., Rembold, M., Gaisberger, M., Hartl, A., Epstein, MM., Matthias, P., Seiser, C., Ellmeier, W. (2010) Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production. J Immunol. 185(6):3489-97

Haider, S., Wagner, M., Schmid, MC., Sixt, BS., Christian, JG., Häcker, G., Pichler, P., Mechtler, K., Müller, A., Baranyi, C., Toenshoff, ER., Montanaro, J., Horn, M. (2010) Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae. Mol Microbiol. 77(3):687-700

Hasenbein, S., Meltzer, M., Hauske, P., Kaiser, M., Huber, R., Clausen, T., Ehrmann, M. (2010) Conversion of a regulatory into a degradative protease. J Mol Biol. 397(4):957-66

Haubner, BJ., Neely, GG., Voelkl, JG., Damilano, F., Kuba, K., Imai, Y., Komnenovic, V., Mayr, A., Pachinger, O., Hirsch, E., Penninger, JM., Metzler, B. (2010) PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway. PLoS One. 5(2):e9350

Heinz, E., Pichler, P., Heinz, C., Op den Camp, HJ., Toenshoff, ER., Ammerer, G., Mechtler, K., Wagner, M., Horn, M. (2010) Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies. Proteomics. 10(24):4363-76

Herrmann, D., Ferrer-Vaquer, A., Lahsnig, C., Firnberg, N., Leibbrandt, A., Neubüser, A. (2010) Expression and regulation of ANTXR1 in the chick embryo. Dev Dyn. 239(2):680-7

Hnisz, D., Majer, O., Frohner, IE., Komnenovic, V., Kuchler, K. (2010) The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans. PLoS Pathog. 6(5):e1000889

Hoelbl, A., Schuster, C., Kovacic, B., Zhu, B., Wickre, M., Hoelzl, MA., Fajmann, S., Grebien, F., Warsch, W., Stengl, G., Hennighausen, L., Poli, V., Beug, H., Moriggl, R., Sexl, V. (2010) Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med. 2(3):98-110

Huang, J., Dorsey, J., Chuikov, S., Pérez-Burgos, L., Zhang, X., Jenuwein, T., Reinberg, D., Berger, SL. (2010) G9a and Glp methylate lysine 373 in the tumor suppressor p53. J Biol Chem. 285(13):9636-41

Huber, MA., Maier, HJ., Alacakaptan, M., Wiedemann, E., Braunger, J., Boehmelt, G., Madwed, JB., Young, ER., Marshall, DR., Pehamberger, H., Wirth, T., Kraut, N., Beug, H. (2010) BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression. Genes Cancer. 1(2):101-14

Hutchins, JR., Toyoda, Y., Hegemann, B., Poser, I., Hériché, JK., Sykora, MM., Augsburg, M., Hudecz, O., Buschhorn, BA., Bulkescher, J., Conrad, C., Comartin, D., Schleiffer, A., Sarov, M., Pozniakovsky, A., Slabicki, MM., Schloissnig, S., Steinmacher, I., Leuschner, M., Ssykor, A., Lawo, S., Pelletier, L., Stark, H., Nasmyth, K., Ellenberg, J., Durbin, R., Buchholz, F., Mechtler, K., Hyman, AA., Peters, JM. (2010) Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 328(5978):593-9

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Kraft, C., Gmachl, M., Peters, JM. (2006) Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex. Methods. 38(1):39-51

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Wagner, B., Natarajan, A., Grünaug, S., Kroismayr, R., Wagner, EF., Sibilia, M. (2006) Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes. EMBO J. 25(4):752-62

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2005

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Angelin-Duclos, C., Domenget, C., Kolbus, A., Beug, H., Jurdic, P., Samarut, J. (2005) Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse.