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Meinrad Busslinger

Acquired immunity to foreign pathogens depends on the differentiation of B and T lymphocytes from hematopoietic stem cells, which is controlled by a multitude of transcription factors. We are interested in understanding the process by which transcription factors regulate the commitment of early hematopoietic progenitors to the B cell lineage and control their subsequent differentiation to mature B cells and plasma cells. We investigate the underlying transcriptional control mechanisms by using mouse transgenic, cell biological, and genome-wide molecular approaches.

Group Members

Anna Sales FEDL
PhD Student
Theresa PINTER
PhD Student
Hiromi TAGOH
Research Associate