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Bing Ren to give Max Birnstiel Lecture

10 Oct 2019

The Research Institute of Molecular Pathology (IMP) cordially invites you to attend the talk

‘Decrypting the Noncoding Genome - Unmasking the role of transcriptional control in complex traits and human disease’

By Bing Ren
UC San Diego School of Medicine

Date: Wed., 16 October 2019, 11.00 a.m.
Venue: IMP Lecture Hall, Campus-Vienna-Biocenter 1, 1030 Vienna

Bing Ren and his lab focus on genomic and epigenomic analyses of human embryonic stem cell differentiation and mammalian development. They have contributed to the annotation of transcriptional regulatory sequences in the human and mouse genomes, to the characterisation of epigenomes of human cell types, and to our knowledge of the chromatin architecture in mammalian cells.

Bing Ren performed his PhD research in Tom Maniatis’s lab at Harvard University and his postdoctoral work in Rick Young’s group at the Whitehead Institute, where he was among the first to develop ChIP-chip for the genome-wide localisation of TF binding sites in yeast and to study the regulation of transcription in yeast. With his own group at UCSD, he was also one of the first to determine histone modifications in the human genome and use them for the prediction of enhancers. 

Bing Ren has been one of the leaders of the ENCODE pilot project, the ENCODE project and the ENCODE project in the mouse – all efforts to understand the non-coding parts of our genomes and how gene regulation is encoded in our genomic sequences. Studying the structure and folding of the human genome with high-resolution HiC, Bing’s group was among the first to observe and name topologically associating domains (TADs). In his talk, Bing Ren will link his work on genomic sequence, structure and function to the characterisation and interpretation of sequence variations as they occur within populations and can be associated with disease.

For his Max Birnstiel Lecture, Bing Ren was invited by Alexander Stark.

About the Max Birnstiel Lectures

The Max Birnstiel Lectures are a special series of seminars at the Research Institute of Molecular Pathology (IMP) in Vienna. They are named after the founding director of the institute, Max L. Birnstiel, who passed away in 2014. Each year, five to six scientists are invited to deliver one of these lectures. Previous lecturers are distinguished leaders in their respective fields, among them a number of Nobel Prize laureates. The Max Birnstiel Lectures attract considerable attention in the wider scientific community and invariably draw a large audience to the IMP.

Programme of the Max Birnstiel Lectures

Videos of past Max Birnstiel Lectures