David Haselbach
Cells are factories full of molecular machines, fuelled by the thermal energy of the surrounding medium. Randomly impacting solution molecules force the machines to vibrate and therefore move in all directions. Only through well-placed structural features, that prohibit some of the random movements can the molecules work productively. Our lab aims to identify and understand design principles of molecular machines. We use biophysical techniques – in particular cryo-electron microscopy – to watch them in action.