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Clemens Plaschka

Messenger RNA (mRNA) maturation is a crucial step in gene expression, requiring the coordinated action of multiple cellular machines. These machines make dramatic changes to the mRNA, the mRNA-bound proteins, and ultimately prepare mature mRNA for export from nucleus to cytoplasm. We apply structural and functional methods to reveal the molecular basis of human mRNA biogenesis and the coordination between maturation events. Our goal is to understand how an mRNA is made.

Group Members

Miguel Angel AGUILAR
PhD Student
Vytaute BOREIKAITE
Postdoc
Rupert William FARAWAY
Postdoc
Laura FIN
Senior Research Assistant
Jean-Marc Raffaello Matteo FURLANO
Master Student
Max GRAF
PhD Student
Constanze Barbara GREMMELMAIER
PhD Student
Bjarne HASTEDT
PhD Student
Nusa KOS THALER
PhD Student
Michelangelo LASSANDRO
Postdoc
Alette Kristine Kristiansen NISSEN
Research Assistant
Alessandro PASSERA
PhD Student
Alexander William PHILLIPS
Senior Research Assistant
Clemens PLASCHKA
Senior Group Leader
Patricia Bianca ROTHE
PhD Student
Matthias Kopano VORLÄNDER
Postdoc

Lab Alumni

Former group members, listed by first arrival in the lab.

Postdocs

Ulrich Hohmann (2019–2026) – then group leader at IMB Mainz
Daria Riabov-Bassat (2022–2025) – then Project Leader in Lab Automation, IMBA

PhD students

Belén Pacheco-Fiallos (2018–2023) – then postdoc with S. Vos at MIT
Ulla Schellhaas (2019–2024) – then Scientific Staff at Illumina
Farja Ayala-Munoz (2019–2024) – then Core Scientist at VBCF
Julia Portell I de Montserrat (2020–2025) – then postdoc with M. Höpfler at CRG

Master students

Thomas Pühringer (2018–2020) – then PhD in the Costa group, Francis Crick Institute
Justus Kleifeld (2020–2022) – then PhD in the Urban group, IMBA
Supapat Visanpattanasin (2021–2022) – then PhD at Northwestern University
Felix Hartmann (2021–2022) – then PhD in the Joao group, Max Perutz Labs
Lalitha Velethi (2022) – then PhD in the Anderson group, Aarhus University
Leonie Opitz (2024–2025) – then PhD in the Querques group, Max Perutz Labs

Undergraduate students

Simon Lichtinger (2019)
Jasmin Kuhn (2019–2020)
Harry Orrin (2021)
Max Kümmecke (2022)