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Welcome to the IMP

The Research Institute of Molecular Pathology (IMP) is a basic biomedical research institute sponsored largely by Boehringer Ingelheim, as well as research grants from national and international funding agencies. Sixteen independent research groups conduct curiosity-driven research spanning a broad range of topics, including computational and structural biology, cell and developmental biology, epigenetics, neurobiology, immunology, and disease mechanisms. Our common goal is to uncover fundamental molecular and cellular mechanisms that underlie complex biological phenomena.

Publication Highlights

McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. (abstract)
Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex. (abstract)
Structural basis for the regulated protease and chaperone function of DegP. (abstract)

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