A new gl’IMPse at Molecular Machines
After the successful introduction of our audio-series "gl’IMPses of research", we present the second episode in what is to be a collection of audio-portraits of IMP scientists, describing in their own words how they became fascinated by their subjects, the questions they are trying to answer, and what they plan to do in the future.
In this episode, we present structural biologist and IMP Fellow David Haselbach who set up his fist independent lab at the IMP in 2017. David talks about the many facets of his research at the interface of physics, biology, and computer science.
In just under 18 minutes, you will find out how he manages to watch macromolecular machines in action by exploiting the power of single particle cryo-EM and how his team uses deep learning approaches to develop new computational tools. You will learn about the medical relevance of protein degradation by the proteasome, virus-strategies to evade degradation, and new ways to drug undruggable proteins.
Listen to IMP Fellow David Haselbach as he talks about watching macromolecular machines in action, the power of cryo-electron microscopy and how his team uses deep learning approaches to develop new computational tools.