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Ref2218: Research Assistant, in vivo models of metastatic cancer

The ERC-funded Obenauf Group at the Research Institute of Molecular Pathology (IMP), in collaboration with Boehringer Ingelheim in Vienna, Austria, is recruiting a highly motivated Research Assistant interested in cancer therapies and disease biology. The successful candidate will establish new in vivo models to rapidly evaluate novel therapeutic concepts and disease dependencies. He/she will be an integral member of a dynamic and ambitious group of scientists to support cutting-edge basic and biomedical research.

The Obenauf lab is a multidisciplinary group interested in the molecular mechanisms underlying tumour progression and immune evasion. Clinical puzzles inspire our work, and we develop and employ a wide array of molecular biology, biochemistry, and in vivo approaches with the vision and mission of guiding rational combination therapies.

Your profile

  • Training in molecular biology (e.g., Master and/or PhD).
  • Strong expertise in mouse work and tissue culture is required.
  • Experience with FACS (to characterize the immune compartment) and molecular cloning/functional genetics skills are a plus. Experience in cancer modelling and metastasis generation in mice is a plus.
  • Collaborative mindset and motivation to work in an international, interdisciplinary environment.
  • Team player with strong communication skills and a proactive “getting things done” mentality.
  • Excellent written and oral communication skills in English (German language skills are not required).

Your tasks

  • Develop new models: Generate new experimentally tractable cancer models to investigate complex disease phenotypes and test new therapeutic concepts in ways that would not be feasible in patients.
  • Evaluate new drug targets: Asses the effects of (novel) compounds and therapy combinations on tumour growth, metastasis in distinct organs (e.g., brain), the tumour microenvironment, and anti-cancer immune responses.
  • Become an integral member of our team: Contribute to cutting-edge cancer research by leading the development of new models and collaborating with our team members. Get involved in additional projects, provide support, and contribute to the team spirit.

The successful candidate will be part of a stimulating research environment at the Vienna BioCenter, a life-science hub in the vibrant city of Vienna, Austria, which is frequently ranked the world’s best city to live in. We provide an unparalleled training opportunity with world-class support at the group-, institute-, and campus-level and closely collaborate with an international network of scientists, clinicians, and industry. The annual gross salary starts from 32,200 Euro, - or higher - for a full-time position (40 hrs/week), depending on qualification and experience and includes a comprehensive benefits package. The employment will be limited to two years with possible extension

Application

Applications, including a letter of motivation describing your particular interest in this position and past research experiences, a CV, and the names and contact details of referees, should be submitted online. The application deadline is January 20th, 2023, but applications are accepted until the position is filled.

Additional information

Group webpage: www.obenauflab.com, IMP: http://www.imp.ac.at.

Selected publications: Leiendecker et al., Cancer Discovery, 2022, Haas et al. Nature Cancer, 2021, Umkehrer et al., Nature Biotechnology, 2020; Leiendecker et al., EMBO Molecular Medicine, 2020; Obenauf et al., Nature, 2015; Obenauf and Massagué, Nature, 2016, and more to come soon!