Thomas Marlovits (joint IMP-IMBA Group Leader)

Molecular Machines

Molecular machines are essential to maintain life at the cellular level.  We aim to understand the fundamental molecular design, assembly processes, and mechanistic details of such higher-order structures.  At our laboratory we are specifically interested in protein translocation machineries that are essential for microbial infection.

 

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Movie (Quick Time Player required)


Movie: Computer-generated model of the of the Infective Apparatus of Salmonella; 
Artwork: IMP-IMBA/ Kulcsar

Selected Publications

2006
Marlovits, TC., Kubori, T., Lara-Tejero, M., Thomas, D., Unger, VM., Galán, JE. (2006). Assembly of the inner rod determines needle length in the type III secretion injectisome. Nature. 441(7093):637-40 (abstract)
 
2004
Marlovits, TC., Kubori, T., Sukhan, A., Thomas, DR., Galán, JE., Unger, VM. (2004). Structural insights into the assembly of the type III secretion needle complex. Science. 306(5698):1040-2 (abstract)
 
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