Keays Group Publications

Pagnamenta, AT., Lise, S., Harrison, V., Stewart, H., Jayawant, S., Quaghebeur, G., Deng, AT., Murphy, VE., Akha, ES., Rimmer, A., Mathieson, I., Knight, SJ., Kini, U., Taylor, JC., Keays, DA. (2012). Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies. J Hum Genet. 57(1):70-2 (abstract)

Treiber, CD., Salzer, MC., Riegler, J., Edelman, N., Sugar, C., Breuss, M., Pichler, P., Cadiou, H., Saunders, M., Lythgoe, M., Shaw, J., Keays, DA. (2012). Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons. Nature. (abstract)

Edwards, A., Treiber, CD., Breuss, M., Pidsley, R., Huang, GJ., Cleak, J., Oliver, PL., Flint, J., Keays, DA. (2011). Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse. Neuroscience. 195:191-200 (abstract)

Stöger-Pollach, M., Treiber, CD., Resch, GP., Keays, DA., Ennen, I. (2011). EMCD real space maps of Magnetospirillum magnetotacticum. Micron. 42(5):456-60 (abstract)

Braun, A., Breuss, M., Salzer, MC., Flint, J., Cowan, NJ., Keays, DA. (2010). Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 86(5):819-22; author reply 822-3 (abstract)

Keays, DA., Cleak, J., Huang, GJ., Edwards, A., Braun, A., Treiber, CD., Pidsley, R., Flint, J. (2010). The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus. Dev Neurosci. 32(4):268-77 (abstract)

Tian, G., Jaglin, XH., Keays, DA., Francis, F., Chelly, J., Cowan, NJ. (2010). Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway. Hum Mol Genet. 19(18):3599-613 (abstract)

Jaglin, XH., Poirier, K., Saillour, Y., Buhler, E., Tian, G., Bahi-Buisson, N., Fallet-Bianco, C., Phan-Dinh-Tuy, F., Kong, XP., Bomont, P., Castelnau-Ptakhine, L., Odent, S., Loget, P., Kossorotoff, M., Snoeck, I., Plessis, G., Parent, P., Beldjord, C., Cardoso, C., Represa, A., Flint, J., Keays, DA., Cowan, NJ., Chelly, J. (2009). Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria. Nat Genet. 41(6):746-52 (abstract)

Groszer, M., Keays, DA., Deacon, RM., de Bono, JP., Prasad-Mulcare, S., Gaub, S., Baum, MG., French, CA., Nicod, J., Coventry, JA., Enard, W., Fray, M., Brown, SD., Nolan, PM., Pääbo, S., Channon, KM., Costa, RM., Eilers, J., Ehret, G., Rawlins, JN., Fisher, SE. (2008). Impaired synaptic plasticity and motor learning in mice with a point mutation implicated in human speech deficits. Curr Biol. 18(5):354-62 (abstract)

Tian, G., Kong, XP., Jaglin, XH., Chelly, J., Keays, D., Cowan, NJ. (2008). A pachygyria-causing alpha-tubulin mutation results in inefficient cycling with CCT and a deficient interaction with TBCB. Mol Biol Cell. 19(3):1152-61 (abstract)

Keays, DA. (2007). Neuronal migration: unraveling the molecular pathway with humans, mice, and a fungus. Mamm Genome. 18(6-7):425-30 (abstract)

Keays, DA., Clark, TG., Campbell, TG., Broxholme, J., Valdar, W. (2007). Estimating the number of coding mutations in genotypic and phenotypic driven N-ethyl-N-nitrosourea (ENU) screens: revisited. Mamm Genome. 18(2):123-4 (abstract)

Keays, DA., Tian, G., Poirier, K., Huang, GJ., Siebold, C., Cleak, J., Oliver, PL., Fray, M., Harvey, RJ., Molnár, Z., Piñon, MC., Dear, N., Valdar, W., Brown, SD., Davies, KE., Rawlins, JN., Cowan, NJ., Nolan, P., Chelly, J., Flint, J. (2007). Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans. Cell. 128(1):45-57 (abstract)

Oliver, PL., Keays, DA., Davies, KE. (2007). Behavioural characterisation of the robotic mouse mutant. Behav Brain Res. 181(2):239-47 (abstract)

Poirier, K., Keays, DA., Francis, F., Saillour, Y., Bahi, N., Manouvrier, S., Fallet-Bianco, C., Pasquier, L., Toutain, A., Tuy, FP., Bienvenu, T., Joriot, S., Odent, S., Ville, D., Desguerre, I., Goldenberg, A., Moutard, ML., Fryns, JP., van Esch, H., Harvey, RJ., Siebold, C., Flint, J., Beldjord, C., Chelly, J. (2007). Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Hum Mutat. 28(11):1055-64 (abstract)

Keays, DA., Clark, TG., Flint, J. (2006). Estimating the number of coding mutations in genotypic- and phenotypic-driven N-ethyl-N-nitrosourea (ENU) screens. Mamm Genome. 17(3):230-8 (abstract)

Livett, BG., Sandall, DW., Keays, D., Down, J., Gayler, KR., Satkunanathan, N., Khalil, Z. (2006). Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor. Toxicon. 48(7):810-29 (abstract)

Bogani, D., Warr, N., Elms, P., Davies, J., Tymowska-Lalanne, Z., Goldsworthy, M., Cox, RD., Keays, DA., Flint, J., Wilson, V., Nolan, P., Arkell, R. (2004). New semidominant mutations that affect mouse development. Genesis. 40(2):109-117 (abstract)

Jakubowski, JA., Keays, DA., Kelley, WP., Sandall, DW., Bingham, JP., Livett, BG., Gayler, KR., Sweedler, JV. (2004). Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry. J Mass Spectrom. 39(5):548-57 (abstract)

Quwailid, MM., Hugill, A., Dear, N., Vizor, L., Wells, S., Horner, E., Fuller, S., Weedon, J., McMath, H., Woodman, P., Edwards, D., Campbell, D., Rodger, S., Carey, J., Roberts, A., Glenister, P., Lalanne, Z., Parkinson, N., Coghill, EL., McKeone, R., Cox, S., Willan, J., Greenfield, A., Keays, D., Brady, S., Spurr, N., Gray, I., Hunter, J., Brown, SD., Cox, RD. (2004). A gene-driven ENU-based approach to generating an allelic series in any gene. Mamm Genome. 15(8):585-91 (abstract)

Yalcin, B., Fullerton, J., Miller, S., Keays, DA., Brady, S., Bhomra, A., Jefferson, A., Volpi, E., Copley, RR., Flint, J., Mott, R. (2004). Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proc Natl Acad Sci U S A. 101(26):9734-9 (abstract)

Keays, DA., Nolan, PM. (2003). N-ethyl-N-nitrosourea mouse mutants in the dissection of behavioural and psychiatric disorders. Eur J Pharmacol. 480(1-3):205-17 (abstract)

Sandall, DW., Satkunanathan, N., Keays, DA., Polidano, MA., Liping, X., Pham, V., Down, JG., Khalil, Z., Livett, BG., Gayler, KR. (2003). A novel alpha-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo. Biochemistry. 42(22):6904-11 (abstract)