Peggy Stolt-Bergner (IMP Fellow)

Transfer of Signals and Substrates Across the Cell Membrane

All cells are surrounded by at least one impermeable lipid bilayer, and have evolved numerous types of proteins to allow them to interact with their environment by transducing signals and transporting substrates across this membrane. We are interested in understanding the molecular mechanisms these proteins use to accomplish their tasks.

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Selected Publications

2006
Beffert, U., Durudas, A., Weeber, EJ., Stolt, PC., Giehl, KM., Sweatt, JD., Hammer, RE., Herz, J. (2006). Functional dissection of Reelin signaling by site-directed disruption of Disabled-1 adaptor binding to apolipoprotein E receptor 2: distinct roles in development and synaptic plasticity. J Neurosci. 26(7):2041-52 (abstract)
 
Stolt, PC., Bock, HH. (2006). Modulation of lipoprotein receptor functions by intracellular adaptor proteins. Cell Signal. 18(10):1560-71 (abstract)
 
Surade, S., Klein, M., Stolt-Bergner, PC., Muenke, C., Roy, A., Michel, H. (2006). Comparative analysis and \"expression space\" coverage of the production of prokaryotic membrane proteins for structural genomics. Protein Sci. 15(9):2178-89 (abstract)
 
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