We are using genetic and molecular approaches to study how the fly (Drosophila melanogaster) learns and forms memories that shape its mating behaviour.
A Drosophila genome-wide transgenic RNAi library has been generated, allowing researchers to systematically study gene functions in specific tissues at specific developmental stages. The VDRC maintains and distributes this library to Drosophila researchers world-wide.
Dietzl, G., Chen, D., Schnorrer, F., Su, KC., Barinova, Y., Fellner, M., Gasser, B., Kinsey, K., Oppel, S., Scheiblauer, S., Couto, A., Marra, V., Keleman, K., Dickson, BJ. (2007). A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.
Nature. 448(7150):151-6
(abstract)
(fulltext)
Keleman, K., Krüttner, S., Alenius, M., Dickson, BJ. (2007). Function of the Drosophila CPEB protein Orb2 in long-term courtship memory.
Nat Neurosci. 10(12):1587-93
(abstract)
