Fluorescence tools operating on a single-molecule scale
Discoveries in biosciences are frequently stimulated by the invention of new scientific tools. We like to push fluorescence techniques beyond the classic spatial and temporal resolution limits. Such low-invasive approaches offer the fascinating prospect of observing biomolecules in their native environment and understanding how they act in concert.
K. Elsayad and K. G. Heinze (2010). Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks
Physical Review A. 81(5)
(fulltext)
2009
Elsayad, K., Heinze, KG. (2009). Defining a superlens operating regime for imaging fluorescent molecules.
PLoS One. 4(12):e7963
(abstract)
Heinze, KG., Costantino, S., De Koninck, P., Wiseman, PW. (2009). Beyond photobleaching, laser illumination unbinds fluorescent proteins.
J Phys Chem B. 113(15):5225-33
(abstract)
2008
Bachir, AI., Kolin, DL., Heinze, KG., Hebert, B., Wiseman, PW. (2008). A guide to accurate measurement of diffusion using fluorescence correlation techniques with blinking quantum dot nanoparticle labels.
J Chem Phys. 128(22):225105
(abstract)
2007
Kim, SA., Heinze, KG., Schwille, P. (2007). Fluorescence correlation spectroscopy in living cells.
Nat Methods. 4(11):963-73
(abstract)
