Publications

2010
Csiszar, A., Vogelsang, E., Beug, H., Leptin, M. (2010). A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission. Mol Cell Biol. 30(8):2017-27 (abstract)
Friedbichler, K., Kerenyi, MA., Kovacic, B., Li, G., Hoelbl, A., Yahiaoui, S., Sexl, V., Müllner, EW., Fajmann, S., Cerny-Reiterer, S., Valent, P., Beug, H., Gouilleux, F., Bunting, KD., Moriggl, R. (2010). Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation. Blood. (abstract)
Hoelbl, A., Schuster, C., Kovacic, B., Zhu, B., Wickre, M., Hoelzl, MA., Fajmann, S., Grebien, F., Warsch, W., Stengl, G., Hennighausen, L., Poli, V., Beug, H., Moriggl, R., Sexl, V. (2010). Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia. EMBO Mol Med. 2(3):98-110 (abstract)
Maier, HJ., Schmidt-Strassburger, U., Huber, MA., Wiedemann, EM., Beug, H., Wirth, T. (2010). NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells. Cancer Lett. 295(2):214-28 (abstract)
Zulehner, G., Mikula, M., Schneller, D., van Zijl, F., Huber, H., Sieghart, W., Grasl-Kraupp, B., Waldhör, T., Peck-Radosavljevic, M., Beug, H., Mikulits, W. (2010). Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence. Am J Pathol. 176(1):472-81 (abstract)
2009
Beug, H. (2009). Breast cancer stem cells: eradication by differentiation therapy? Cell. 138(4):623-5 (abstract)
Ecker, A., Simma, O., Hoelbl, A., Kenner, L., Beug, H., Moriggl, R., Sexl, V. (2009). The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor. Front Biosci. 14:2944-58 (abstract)
Lahsnig, C., Mikula, M., Petz, M., Zulehner, G., Schneller, D., van Zijl, F., Huber, H., Csiszar, A., Beug, H., Mikulits, W. (2009). ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression. Oncogene. 28(5):638-50 (abstract)
van Zijl, F., Mair, M., Csiszar, A., Schneller, D., Zulehner, G., Huber, H., Eferl, R., Beug, H., Dolznig, H., Mikulits, W. (2009). Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge. Oncogene. 28(45):4022-33 (abstract)
2008
Gal, A., Sjöblom, T., Fedorova, L., Imreh, S., Beug, H., Moustakas, A. (2008). Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis. Oncogene. 27(9):1218-30 (abstract)
Grebien, F., Kerenyi, MA., Kovacic, B., Kolbe, T., Becker, V., Dolznig, H., Pfeffer, K., Klingmüller, U., Müller, M., Beug, H., Müllner, EW., Moriggl, R. (2008). Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2. Blood. 111(9):4511-22 (abstract)
Grech, G., Blázquez-Domingo, M., Kolbus, A., Bakker, WJ., Müllner, EW., Beug, H., von Lindern, M. (2008). Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation. Blood. 112(7):2750-60 (abstract)
Kerenyi, MA., Grebien, F., Gehart, H., Schifrer, M., Artaker, M., Kovacic, B., Beug, H., Moriggl, R., Müllner, EW. (2008). Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. Blood. 112(9):3878-88 (abstract)
Kornfeld, JW., Grebien, F., Kerenyi, MA., Friedbichler, K., Kovacic, B., Zankl, B., Hoelbl, A., Nivarti, H., Beug, H., Sexl, V., Muller, M., Kenner, L., Mullner, EW., Gouilleux, F., Moriggl, R. (2008). The different functions of Stat5 and chromatin alteration through Stat5 proteins. Front Biosci. 13:6237-54 (abstract)
Schähs, P., Weidinger, P., Probst, OC., Svoboda, B., Stadlmann, J., Beug, H., Waerner, T., Mach, L. (2008). Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis. Exp Cell Res. 314(16):3036-47 (abstract)
2007
Aigner, K., Dampier, B., Descovich, L., Mikula, M., Sultan, A., Schreiber, M., Mikulits, W., Brabletz, T., Strand, D., Obrist, P., Sommergruber, W., Schweifer, N., Wernitznig, A., Beug, H., Foisner, R., Eger, A. (2007). The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene. 26(49):6979-88 (abstract)
Aigner, K., Descovich, L., Mikula, M., Sultan, A., Dampier, B., Bonné, S., van Roy, F., Mikulits, W., Schreiber, M., Brabletz, T., Sommergruber, W., Schweifer, N., Wernitznig, A., Beug, H., Foisner, R., Eger, A. (2007). The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression. FEBS Lett. 581(8):1617-24 (abstract)
Bakker, WJ., van Dijk, TB., Parren-van Amelsvoort, M., Kolbus, A., Yamamoto, K., Steinlein, P., Verhaak, RG., Mak, TW., Beug, H., Löwenberg, B., von Lindern, M. (2007). Differential regulation of Foxo3a target genes in erythropoiesis. Mol Cell Biol. 27(10):3839-3854 (abstract)
Engblom, D., Kornfeld, JW., Schwake, L., Tronche, F., Reimann, A., Beug, H., Hennighausen, L., Moriggl, R., Schütz, G. (2007). Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression. Genes Dev. 21(10):1157-62 (abstract)
Fischer, AN., Fuchs, E., Mikula, M., Huber, H., Beug, H., Mikulits, W. (2007). PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression. Oncogene. 26(23):3395-405 (abstract)
Harir, N., Pecquet, C., Kerenyi, M., Sonneck, K., Kovacic, B., Nyga, R., Brevet, M., Dhennin, I., Gouilleux-Gruart, V., Beug, H., Valent, P., Lassoued, K., Moriggl, R., Gouilleux, F. (2007). Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias. Blood. 109(4):1678-86 (abstract)
Hui, L., Bakiri, L., Mairhorfer, A., Schweifer, N., Haslinger, C., Kenner, L., Komnenovic, V., Scheuch, H., Beug, H., Wagner, EF. (2007). p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway. Nat Genet. 39(6):741-9 (abstract)
Naetar, N., Hutter, S., Dorner, D., Dechat, T., Korbei, B., Gotzmann, J., Beug, H., Foisner, R. (2007). LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J Cell Sci. 120(Pt 5):737-47 (abstract)
Rath, O., Himmler, A., Baum, A., Sommergruber, W., Beug, H., Metz, T. (2007). c-Myc is required for transformation of FDC-P1 cells by EGFRvIII. FEBS Lett. 581(13):2549-56 (abstract)
2006
Dolznig, H., Grebien, F., Deiner, EM., Stangl, K., Kolbus, A., Habermann, B., Kerenyi, MA., Kieslinger, M., Moriggl, R., Beug, H., Müllner, EW. (2006). Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR. Oncogene. 25(20):2890-900 (abstract)
Gotzmann, J., Fischer, AN., Zojer, M., Mikula, M., Proell, V., Huber, H., Jechlinger, M., Waerner, T., Weith, A., Beug, H., Mikulits, W. (2006). A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes. Oncogene. 25(22):3170-85 (abstract)
Hernandez-Hernandez, A., Ray, P., Litos, G., Ciro, M., Ottolenghi, S., Beug, H., Boyes, J. (2006). Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1. EMBO J. 25(14):3264-74 (abstract)
Hoelbl, A., Kovacic, B., Kerenyi, MA., Simma, O., Warsch, W., Cui, Y., Beug, H., Hennighausen, L., Moriggl, R., Sexl, V. (2006). Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation. Blood. 107(12):4898-906 (abstract)
Janda, E., Nevolo, M., Lehmann, K., Downward, J., Beug, H., Grieco, M. (2006). Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene. 25(54):7117-30 (abstract)
Jechlinger, M., Sommer, A., Moriggl, R., Seither, P., Kraut, N., Capodiecci, P., Donovan, M., Cordon-Cardo, C., Beug, H., Grünert, S. (2006). Autocrine PDGFR signaling promotes mammary cancer metastasis. J Clin Invest. 116(6):1561-70 (abstract)
Kovacic, B., Stoiber, D., Moriggl, R., Weisz, E., Ott, RG., Kreibich, R., Levy, DE., Beug, H., Freissmuth, M., Sexl, V. (2006). STAT1 acts as a tumor promoter for leukemia development. Cancer Cell. 10(1):77-87 (abstract)
Rubiolo, C., Piazzolla, D., Meissl, K., Beug, H., Huber, JC., Kolbus, A., Baccarini, M. (2006). A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation. Blood. 108(1):152-9 (abstract)
Schranzhofer, M., Schifrer, M., Cabrera, JA., Kopp, S., Chiba, P., Beug, H., Müllner, EW. (2006). Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood. 107(10):4159-67 (abstract)
Waerner, T., Alacakaptan, M., Tamir, I., Oberauer, R., Gal, A., Brabletz, T., Schreiber, M., Jechlinger, M., Beug, H. (2006). ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells. Cancer Cell. 10(3):227-39 (abstract)
2005
Angelin-Duclos, C., Domenget, C., Kolbus, A., Beug, H., Jurdic, P., Samarut, J. (2005). Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse. Development. 132(5):925-34 (abstract)
Corvinus, FM., Orth, C., Moriggl, R., Tsareva, SA., Wagner, S., Pfitzner, EB., Baus, D., Kaufmann, R., Huber, LA., Zatloukal, K., Beug, H., Ohlschläger, P., Schütz, A., Halbhuber, KJ., Friedrich, K. (2005). Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth. Neoplasia. 7(6):545-55 (abstract)
Dolznig, H., Kolbus, A., Leberbauer, C., Schmidt, U., Deiner, EM., Müllner, EW., Beug, H. (2005). Expansion and differentiation of immature mouse and human hematopoietic progenitors. Methods Mol Med. 105:323-44 (abstract)
Drissen, R., von Lindern, M., Kolbus, A., Driegen, S., Steinlein, P., Beug, H., Grosveld, F., Philipsen, S. (2005). The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability. Mol Cell Biol. 25(12):5205-14 (abstract)
Eger, A., Aigner, K., Sonderegger, S., Dampier, B., Oehler, S., Schreiber, M., Berx, G., Cano, A., Beug, H., Foisner, R. (2005). DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells. Oncogene. 24(14):2375-85 (abstract)
Fischer, AN., Herrera, B., Mikula, M., Proell, V., Fuchs, E., Gotzmann, J., Schulte-Hermann, R., Beug, H., Mikulits, W. (2005). Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis. Carcinogenesis. 26(5):931-42 (abstract)
Grebien, F., Dolznig, H., Beug, H., Mullner, EW. (2005). Cell size control: new evidence for a general mechanism. Cell Cycle. 4(3):418-21 (abstract)
Huber, MA., Kraut, N., Beug, H. (2005). Molecular requirements for epithelial-mesenchymal transition during tumor progression. Curr Opin Cell Biol. 17(5):548-58 (abstract)
Leberbauer, C., Boulmé, F., Unfried, G., Huber, J., Beug, H., Müllner, EW. (2005). Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors. Blood. 105(1):85-94 (abstract)
Maschler, S., Wirl, G., Spring, H., Bredow, DV., Sordat, I., Beug, H., Reichmann, E. (2005). Tumor cell invasiveness correlates with changes in integrin expression and localization. Oncogene. 24(12):2032-41 (abstract)
Moriggl, R., Sexl, V., Kenner, L., Duntsch, C., Stangl, K., Gingras, S., Hoffmeyer, A., Bauer, A., Piekorz, R., Wang, D., Bunting, KD., Wagner, EF., Sonneck, K., Valent, P., Ihle, JN., Beug, H. (2005). Stat5 tetramer formation is associated with leukemogenesis. Cancer Cell. 7(1):87-99 (abstract)
Pilat, S., Carotta, S., Schiedlmeier, B., Kamino, K., Mairhofer, A., Will, E., Modlich, U., Steinlein, P., Ostertag, W., Baum, C., Beug, H., Klump, H. (2005). HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. Proc Natl Acad Sci U S A. 102(34):12101-6 (abstract)
2004
Bakker, WJ., Blázquez-Domingo, M., Kolbus, A., Besooyen, J., Steinlein, P., Beug, H., Coffer, PJ., Löwenberg, B., von Lindern, M., van Dijk, TB. (2004). FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J Cell Biol. 164(2):175-84 (abstract)
Carotta, S., Pilat, S., Mairhofer, A., Schmidt, U., Dolznig, H., Steinlein, P., Beug, H. (2004). Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells. Blood. 104(6):1873-80 (abstract)
Dolznig, H., Grebien, F., Sauer, T., Beug, H., Müllner, EW. (2004). Evidence for a size-sensing mechanism in animal cells. Nat Cell Biol. 6(9):899-905 (abstract)
Eger, A., Stockinger, A., Park, J., Langkopf, E., Mikula, M., Gotzmann, J., Mikulits, W., Beug, H., Foisner, R. (2004). beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition. Oncogene. 23(15):2672-2680 (abstract)
Gotzmann, J., Mikula, M., Eger, A., Schulte-Hermann, R., Foisner, R., Beug, H., Mikulits, W. (2004). Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. Mutat Res. 566(1):9-20 (abstract)
Huber, MA., Azoitei, N., Baumann, B., Grünert, S., Sommer, A., Pehamberger, H., Kraut, N., Beug, H., Wirth, T. (2004). NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression. J Clin Invest. 114(4):569-81 (abstract)
Huber, MA., Beug, H., Wirth, T. (2004). Epithelial-mesenchymal transition: NF-kappaB takes center stage. Cell Cycle. 3(12):1477-80 (abstract)
Joosten, M., Blázquez-Domingo, M., Lindeboom, F., Boulmé, F., Van Hoven-Beijen, A., Habermann, B., Löwenberg, B., Beug, H., Müllner, EW., Delwel, R., Von Lindern, M. (2004). Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling. J Biol Chem. 279(37):38169-76 (abstract)
Maschler, S., Grunert, S., Danielopol, A., Beug, H., Wirl, G. (2004). Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells. Oncogene. 23(20):3622-33 (abstract)
Mikula, M., Fuchs, E., Huber, H., Beug, H., Schulte-Hermann, R., Mikulits, W. (2004). Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation. Hepatology. 39(3):628-34 (abstract)
Schmidt, U., van den Akker, E., Parren-van Amelsvoort, M., Litos, G., de Bruijn, M., Gutiérrez, L., Hendriks, RW., Ellmeier, W., Löwenberg, B., Beug, H., von Lindern, M. (2004). Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med. 199(6):785-95 (abstract)
Tronche, F., Opherk, C., Moriggl, R., Kellendonk, C., Reimann, A., Schwake, L., Reichardt, HM., Stangl, K., Gau, D., Hoeflich, A., Beug, H., Schmid, W., Schütz, G. (2004). Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth. Genes Dev. 18(5):492-7 (abstract)
van den Akker, E., van Dijk, TB., Schmidt, U., Felida, L., Beug, H., Löwenberg, B., von Lindern, M. (2004). The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity. Biol Chem. 385(5):409-13 (abstract)
von Lindern, M., Schmidt, U., Beug, H. (2004). Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase. Cell Cycle. 3(7):876-9 (abstract)
2003
Dazy, S., Damiola, F., Parisey, N., Beug, H., Gandrillon, O. (2003). The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells. Oncogene. 22(58):9205-16 (abstract)
Grünert, S., Jechlinger, M., Beug, H. (2003). Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis. Nat Rev Mol Cell Biol. 4(8):657-65 (abstract)
Jechlinger, M., Grunert, S., Tamir, IH., Janda, E., Lüdemann, S., Waerner, T., Seither, P., Weith, A., Beug, H., Kraut, N. (2003). Expression profiling of epithelial plasticity in tumor progression. Oncogene. 22(46):7155-69 (abstract)
Kolbus, A., Blázquez-Domingo, M., Carotta, S., Bakker, W., Luedemann, S., von Lindern, M., Steinlein, P., Beug, H. (2003). Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling. Blood. 102(9):3136-46 (abstract)
Lebigot, I., Gardellin, P., Lefebvre, L., Beug, H., Ghysdael, J., Quang, CT. (2003). Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling. Blood. 102(13):4555-62 (abstract)
Mikula, M., Gotzmann, J., Fischer, AN., Wolschek, MF., Thallinger, C., Schulte-Hermann, R., Beug, H., Mikulits, W. (2003). The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis. Oncogene. 22(43):6725-38 (abstract)
2002
Dolznig, H., Habermann, B., Stangl, K., Deiner, EM., Moriggl, R., Beug, H., Müllner, EW. (2002). Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts. Curr Biol. 12(13):1076-85 (abstract)
González-Sancho, JM., Figueroa, A., López-Barahona, M., López, E., Beug, H., Muñoz, A. (2002). Inhibition of proliferation and expression of T1 and cyclin D1 genes by thyroid hormone in mammary epithelial cells. Mol Carcinog. 34(1):25-34 (abstract)
Gotzmann, J., Huber, H., Thallinger, C., Wolschek, M., Jansen, B., Schulte-Hermann, R., Beug, H., Mikulits, W. (2002). Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness. J Cell Sci. 115(Pt 6):1189-202 (abstract)
Janda, E., Lehmann, K., Killisch, I., Jechlinger, M., Herzig, M., Downward, J., Beug, H., Grünert, S. (2002). Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J Cell Biol. 156(2):299-313 (abstract)
Janda, E., Litos, G., Grünert, S., Downward, J., Beug, H. (2002). Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway. Oncogene. 21(33):5148-59 (abstract)
Jechlinger, M., Grünert, S., Beug, H. (2002). Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling. J Mammary Gland Biol Neoplasia. 7(4):415-32 (abstract)
Kolbus, A., Pilat, S., Husak, Z., Deiner, EM., Stengl, G., Beug, H., Baccarini, M. (2002). Raf-1 antagonizes erythroid differentiation by restraining caspase activation. J Exp Med. 196(10):1347-53 (abstract)
Lobmayr, L., Sauer, T., Killisch, I., Schranzhofer, M., Wilson, RB., Ponka, P., Beug, H., Müllner, EW. (2002). Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus. Blood. 100(1):289-98 (abstract)
Schulte, CE., von Lindern, M., Steinlein, P., Beug, H., Wiedemann, LM. (2002). MLL-ENL cooperates with SCF to transform primary avian multipotent cells. EMBO J. 21(16):4297-306 (abstract)
Stroissnigg, H., Repitz, M., Miloloza, A., Linhartova, I., Beug, H., Wiche, G., Propst, F. (2002). FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation. Exp Cell Res. 278(2):133-45 (abstract)
Vécsey-Semjén, B., Becker, KF., Sinski, A., Blennow, E., Vietor, I., Zatloukal, K., Beug, H., Wagner, E., Huber, LA. (2002). Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers. Oncogene. 21(30):4646-62 (abstract)
2001
Bauer, A., Gandrillon, O., Samarut, J., Beug, H. (2001). Nuclear receptors in hematopoietic development: cooperation with growth factor receptors in regulation of proliferation and differentiation. Hematopoiesis. A developmental approach (Zon, L., ed.). :368-390
Czvitkovich, S., Sauer, S., Peters, AH., Deiner, E., Wolf, A., Laible, G., Opravil, S., Beug, H., Jenuwein, T. (2001). Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice. Mech Dev. 107(1-2):141-53 (abstract)
Dolznig, H., Boulmé, F., Stangl, K., Deiner, EM., Mikulits, W., Beug, H., Müllner, EW. (2001). Establishment of normal, terminally differentiating mouse erythroid progenitors: molecular characterization by cDNA arrays. FASEB J. 15(8):1442-4 (abstract)
Hofmann, JF., Sykora, M., Redemann, N., Beug, H. (2001). G1-Cdk activity is required for both proliferation and viability of cytokine-dependent myeloid and erythroid cells. Oncogene. 20(31):4198-208 (abstract)
Mikula, M., Schreiber, M., Husak, Z., Kucerova, L., Rüth, J., Wieser, R., Zatloukal, K., Beug, H., Wagner, EF., Baccarini, M. (2001). Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene. EMBO J. 20(8):1952-62 (abstract)
Pradet-Balade, B., Boulmé, F., Beug, H., Müllner, EW., Garcia-Sanz, JA. (2001). Translation control: bridging the gap between genomics and proteomics? Trends Biochem Sci. 26(4):225-9 (abstract)
Reichardt, HM., Horsch, K., Gröne, HJ., Kolbus, A., Beug, H., Hynes, N., Schütz, G. (2001). Mammary gland development and lactation are controlled by different glucocorticoid receptor activities. Eur J Endocrinol. 145(4):519-27 (abstract)
Stockinger, A., Eger, A., Wolf, J., Beug, H., Foisner, R. (2001). E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity. J Cell Biol. 154(6):1185-96 (abstract)
von Lindern, M., Deiner, EM., Dolznig, H., Parren-Van Amelsvoort, M., Hayman, MJ., Mullner, EW., Beug, H. (2001). Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis. Oncogene. 20(28):3651-64 (abstract)
2000
Eger, A., Stockinger, A., Schaffhauser, B., Beug, H., Foisner, R. (2000). Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity. J Cell Biol. 148(1):173-88 (abstract)
Ghysdael, J., Tran Quang, C., Deiner, EM., Dolznig, H., Müllner, EW., Beug, H. (2000). Erythroid cell development and leukemic transformation: interplay between signal transduction, cell cycle control and oncogenes. Pathol Biol (Paris). 48(3):211-26 (abstract)
Kieslinger, M., Woldman, I., Moriggl, R., Hofmann, J., Marine, JC., Ihle, JN., Beug, H., Decker, T. (2000). Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation. Genes Dev. 14(2):232-44 (abstract)
Lehmann, K., Janda, E., Pierreux, CE., Rytömaa, M., Schulze, A., McMahon, M., Hill, CS., Beug, H., Downward, J. (2000). Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells. Genes Dev. 14(20):2610-22 (abstract)
Mikulits, W., Pradet-Balade, B., Habermann, B., Beug, H., Garcia-Sanz, JA., Müllner, EW. (2000). Isolation of translationally controlled mRNAs by differential screening. FASEB J. 14(11):1641-52 (abstract)
Mikulits, W., Schranzhofer, M., Deiner, EM., Beug, H., Müllner, EW. (2000). Regulation of ferritin mRNA translation in primary erythroblasts: exogenous c-Kit plus EpoR signaling mimics v-ErbA oncoprotein activity. Biochem Biophys Res Commun. 275(2):292-4 (abstract)
Petritsch, C., Beug, H., Balmain, A., Oft, M. (2000). TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest. Genes Dev. 14(24):3093-101 (abstract)
Urnov, FD., Yee, J., Sachs, L., Collingwood, TN., Bauer, A., Beug, H., Shi, YB., Wolffe, AP. (2000). Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway. EMBO J. 19(15):4074-90 (abstract)
von Lindern, M., Parren-van Amelsvoort, M., van Dijk, T., Deiner, E., van den Akker, E., van Emst-de Vries, S., Willems, P., Beug, H., Löwenberg, B. (2000). Protein kinase C alpha controls erythropoietin receptor signaling. J Biol Chem. 275(44):34719-27 (abstract)
1999
Bauer, A., Tronche, F., Wessely, O., Kellendonk, C., Reichardt, HM., Steinlein, P., Schütz, G., Beug, H. (1999). The glucocorticoid receptor is required for stress erythropoiesis. Genes Dev. 13(22):2996-3002 (abstract)
Gandrillon, O., Schmidt, U., Beug, H., Samarut, J. (1999). TGF-beta cooperates with TGF-alpha to induce the self-renewal of normal erythrocytic progenitors: evidence for an autocrine mechanism. EMBO J. 18(10):2764-81 (abstract)
Jansen, MW., von Lindern, M., Beug, H., Brandenburg, H., Wildschut, HI., Wladimiroff, JW., In 't Veld, PA. (1999). The use of in vitro expanded erythroid cells in a model system for the isolation of fetal cells from maternal blood. Prenat Diagn. 19(4):323-9 (abstract)
Lucas, T., Krugluger, W., Samorapoompichit, P., Gamperl, R., Beug, H., Förster, O., Boltz-Nitulescu, G. (1999). Self-renewal, maturation, and differentiation of the rat myelomonocytic hematopoietic stem cell. FASEB J. 13(2):263-72 (abstract)
Mikulits, W., Schranzhofer, M., Bauer, A., Dolznig, H., Lobmayr, L., Infante, AA., Beug, H., Müllner, EW. (1999). Impaired ferritin mRNA translation in primary erythroid progenitors: shift to iron-dependent regulation by the v-ErbA oncoprotein. Blood. 94(12):4321-32 (abstract)
Mikulits, W., Schranzhofer, M., Beug, H., Müllner, EW. (1999). Post-transcriptional control via iron-responsive elements: the impact of aberrations in hereditary disease. Mutat Res. 437(3):219-30 (abstract)
Oliferenko, S., Paiha, K., Harder, T., Gerke, V., Schwärzler, C., Schwarz, H., Beug, H., Günthert, U., Huber, LA. (1999). Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton. J Cell Biol. 146(4):843-54 (abstract)
Pereira, R., Quang, CT., Lesault, I., Dolznig, H., Beug, H., Ghysdael, J. (1999). FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts. Oncogene. 18(8):1597-608 (abstract)
von Lindern, M., Zauner, W., Mellitzer, G., Steinlein, P., Fritsch, G., Huber, K., Löwenberg, B., Beug, H. (1999). The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro. Blood. 94(2):550-9 (abstract)
Wessely, O., Bauer, A., Quang, CT., Deiner, EM., von Lindern, M., Mellitzer, G., Steinlein, P., Ghysdael, J., Beug, H. (1999). A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor. Biol Chem. 380(2):187-202 (abstract)
1998
Bauer, A., Mikulits, W., Lagger, G., Stengl, G., Brosch, G., Beug, H. (1998). The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors. EMBO J. 17(15):4291-303 (abstract)
Ciana, P., Braliou, GG., Demay, FG., von Lindern, M., Barettino, D., Beug, H., Stunnenberg, HG. (1998). Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo. EMBO J. 17(24):7382-94 (abstract)
Dahl, R., Kieslinger, M., Beug, H., Hayman, MJ. (1998). Transformation of hematopoietic cells by the Ski oncoprotein involves repression of retinoic acid receptor signaling. Proc Natl Acad Sci U S A. 95(19):11187-92 (abstract)
Fialka, I., Oft, M., Reichmann, E., Huber, LA., Beug, H. (1998). Three-dimensional organotypic growth of epithelial cells in reconstituted extracellular matrix. Cell Biology - A Laboratory Handbook (ed. Celis, JE.). 1:107-12
Oft, M., Heider, KH., Beug, H. (1998). TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis. Curr Biol. 8(23):1243-52 (abstract)
Reichardt, HM., Kaestner, KH., Tuckermann, J., Kretz, O., Wessely, O., Bock, R., Gass, P., Schmid, W., Herrlich, P., Angel, P., Schütz, G. (1998). DNA binding of the glucocorticoid receptor is not essential for survival. Cell. 93(4):531-41 (abstract)
von Lindern, M., Boer, L., Wessely, O., Parker, M., Beug, H. (1998). The transactivation domain AF-2 but not the DNA-binding domain of the estrogen receptor is required to inhibit differentiation of avian erythroid progenitors. Mol Endocrinol. 12(2):263-77 (abstract)
Wessely, O., Deiner, EM., Lim, KC., Mellitzer, G., Steinlein, P., Beug, H. (1998). Mammalian granulocyte-macrophage colony-stimulating factor receptor expressed in primary avian hematopoietic progenitors: lineage-specific regulation of proliferation and differentiation. J Cell Biol. 141(4):1041-51 (abstract)
1997
Bauer, A., Ulrich, E., Andersson, M., Beug, H., von Lindern, M. (1997). Mechanism of transformation by v-ErbA: substitution for steroid hormone receptor function in self renewal induction. Oncogene. 15(6):701-15 (abstract)
Fuchs, B., Wagner, T., Rössel, N., Antoine, M., Beug, H., Niessing, J. (1997). Structure and erythroid cell-restricted expression of a chicken cDNA encoding a novel zinc finger protein of the Cys + His class. Gene. 195(2):277-84 (abstract)
Mikulits, W., Dolznig, H., Edelmann, H., Sauer, T., Deiner, EM., Ballou, L., Beug, H., Müllner, EW. (1997). Dynamics of cell cycle regulators: artifact-free analysis by recultivation of cells synchronized by centrifugal elutriation. DNA Cell Biol. 16(7):849-59 (abstract)
Quang, CT., Wessely, O., Pironin, M., Beug, H., Ghysdael, J. (1997). Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation. EMBO J. 16(18):5639-53 (abstract)
Schroeder, C., Beug, H., Müller-Esterl, W. (1997). Cloning and functional characterization of the ornithokinin receptor. Recognition of the major kinin receptor antagonist, HOE140, as a full agonist. J Biol Chem. 272(19):12475-81 (abstract)
van't Hof, RJ., von Lindern, M., Nijweide, PJ., Beug, H. (1997). Stem cell factor stimulates chicken osteoclast activity in vitro. FASEB J. 11(4):287-93 (abstract)
Wessely, O., Deiner, EM., Beug, H., von Lindern, M. (1997). The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors. EMBO J. 16(2):267-80 (abstract)
Wessely, O., Mellitzer, G., von Lindern, M., Levitzki, A., Gazit, A., Ischenko, I., Hayman, MJ., Beug, H. (1997). Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 8(5):481-93 (abstract)
Woldman, I., Mellitzer, G., Kieslinger, M., Buchhart, D., Meinke, A., Beug, H., Decker, T. (1997). STAT5 involvement in the differentiation response of primary chicken myeloid progenitor cells to chicken myelomonocytic growth factor. J Immunol. 159(2):877-86 (abstract)
1996
Bartůnĕk, P., Pichlíková, L., Stengl, G., Boehmelt, G., Martin, FH., Beug, H., Dvorák, M., Zenke, M. (1996). Avian stem cell factor (SCF): production and characterization of the recombinant His-tagged SCF of chicken and its neutralizing antibody. Cytokine. 8(1):14-20 (abstract)
Beug, H., Bauer, A., Dolznig, H., von Lindern, M., Lobmayer, L., Mellitzer, G., Steinlein, P., Wessely, O., Mullner, E. (1996). Avian erythropoiesis and erythroleukemia: towards understanding the role of the biomolecules involved. Biochim Biophys Acta. 1288(3):M35-47 (abstract)
Beug, H., Metz, T., Müllner, EW., Hayman, MJ. (1996). Self renewal and differentiation in primary avian hematopoietic cells: an alternative to mammalian in vitro models? Curr Top Microbiol Immunol. 211:29-39 (abstract)
Briegel, K., Bartunek, P., Stengl, G., Lim, KC., Beug, H., Engel, JD., Zenke, M. (1996). Regulation and function of transcription factor GATA-1 during red blood cell differentiation. Development. 122(12):3839-50 (abstract)
Fialka, I., Schwarz, H., Reichmann, E., Oft, M., Busslinger, M., Beug, H. (1996). The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions. J Cell Biol. 132(6):1115-32 (abstract)
Huber, K., Wolf, H., Van Lindern, M., Worofka, B., Rosen, A., Hafner, E., Beug, H., Philipp, K., Bauer, K. (1996). Development of a rapid means of estimating the haemoglobin F content of candidate fetal cells isolated from maternal blood using HPLC. Prenat Diagn. 16(11):1011-9 (abstract)
Mellitzer, G., Wessely, O., Decker, T., Meinke, A., Hayman, MJ., Beug, H. (1996). Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation. Proc Natl Acad Sci U S A. 93(18):9600-5 (abstract)
Müllner, EW., Dolznig, H., Beug, H. (1996). Cell cycle regulation and erythroid differentiation. Curr Top Microbiol Immunol. 212:175-94 (abstract)
Oft, M., Peli, J., Rudaz, C., Schwarz, H., Beug, H., Reichmann, E. (1996). TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells. Genes Dev. 10(19):2462-77 (abstract)
1995
Beug, H., Dahl, R., Steinlein, P., Meyer, S., Deiner, EM., Hayman, MJ. (1995). In vitro growth of factor-dependent multipotential hematopoietic cells is induced by the nuclear oncoprotein v-Ski. Oncogene. 11(1):59-72 (abstract)
Beug, H., Schroeder, C., Wessely, O., Deiner, E., Meyer, S., Ischenko, ID., Hayman, MJ. (1995). Transformation of erythroid progenitors by viral and cellular tyrosine kinases. Cell Growth Differ. 6(8):999-1008 (abstract)
Beug, H., Steinlein, P., Bartunek, P., Hayman, MJ. (1995). Avian hematopoietic cell culture: in vitro model systems to study oncogenic transformation of hematopoietic cells. Methods Enzymol. 254:41-76 (abstract)
Dolznig, H., Bartunek, P., Nasmyth, K., Müllner, EW., Beug, H. (1995). Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control. Cell Growth Differ. 6(11):1341-52 (abstract)
López-Barahona, M., Fialka, I., González-Sancho, JM., Asunción, M., González, M., Iglesias, T., Bernal, J., Beug, H., Muñoz, A. (1995). Thyroid hormone regulates stromelysin expression, protease secretion and the morphogenetic potential of normal polarized mammary epithelial cells. EMBO J. 14(6):1145-55 (abstract)
Quang, CT., Pironin, M., von Lindern, M., Beug, H., Ghysdael, J. (1995). Spi-1 and mutant p53 regulate different aspects of the proliferation and differentiation control of primary erythroid progenitors. Oncogene. 11(7):1229-39 (abstract)
Steinlein, P., Wessely, O., Meyer, S., Deiner, EM., Hayman, MJ., Beug, H. (1995). Primary, self-renewing erythroid progenitors develop through activation of both tyrosine kinase and steroid hormone receptors. Curr Biol. 5(2):191-204 (abstract)
1994
Beug, H., Müllner, EW., Hayman, MJ. (1994). Insights into erythroid differentiation obtained from studies on avian erythroblastosis virus. Curr Opin Cell Biol. 6(6):816-24 (abstract)
Enrietto, PJ., Beug, H. (1994). Introduction: oncogenes and differentiation. Semin Cancer Biol. 5(2):91-4 (abstract)
Gruber, J., Sgonc, R., Hu, YH., Beug, H., Wick, G. (1994). Thymocyte apoptosis induced by elevated endogenous corticosterone levels. Eur J Immunol. 24(5):1115-21 (abstract)
Huber, LA., Beug, H., Simons, K., Reichmann, E. (1994). Two-dimensional gel mapping of small GTPases reveals transformation-specific changes during oncogenesis. Electrophoresis. 15(3-4):469-73 (abstract)
Steinlein, P., Deiner, E., Leutz, A., Beug, H. (1994). Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro. Growth Factors. 10(1):1-16 (abstract)
Vennström, B., Raynoscheck, C., Jansson, L., Doederlein, G., Lhotak, V., Johnsson, A., Beug, H. (1994). Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities. Oncogene. 9(5):1307-20 (abstract)
1993
Barettino, D., Bugge, TH., Bartunek, P., Vivanco Ruiz, MD., Sonntag-Buck, V., Beug, H., Zenke, M., Stunnenberg, HG. (1993). Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR. EMBO J. 12(4):1343-54 (abstract)
Boehmelt, G., Beug, H., Enrietto, PJ., Zenke, M. (1993). A hormone-inducible v-rel estrogen receptor fusion as a means to transform early hematopoietic progenitor cells and to study their differentiation pathway. Les Colloques de I' I.N.R.A.. 62:337-41
Briegel, K., Lim, KC., Plank, C., Beug, H., Engel, JD., Zenke, M. (1993). Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner. Genes Dev. 7(6):1097-109 (abstract)
Hayman, MJ., Meyer, S., Martin, F., Steinlein, P., Beug, H. (1993). Self-renewal and differentiation of normal avian erythroid progenitor cells: regulatory roles of the TGF alpha/c-ErbB and SCF/c-kit receptors. Cell. 74(1):157-69 (abstract)
Larsen, J., Meyer, S., Steinlein, P., Beug, H., Hayman, MJ. (1993). Transformation of chicken bone marrow cells by the v-ski oncogene. Oncogene. 8(12):3221-8 (abstract)
Lee, EB., Beug, H., Hayman, MJ. (1993). Mutational analysis of the role of the carboxy-terminal region of the v-erbB protein in erythroid cell transformation. Oncogene. 8(5):1317-27 (abstract)
Muñoz, A., Wrighton, C., Seliger, B., Bernal, J., Beug, H. (1993). Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12. J Cell Biol. 121(2):423-38 (abstract)
Schroeder, C., Gibson, L., Nordström, C., Beug, H. (1993). The estrogen receptor cooperates with the TGF alpha receptor (c-erbB) in regulation of chicken erythroid progenitor self-renewal. EMBO J. 12(3):951-60 (abstract)
Sokanathan, S., Moll, T., Siegmund, R., Dirick, L., Koch, C., Beug, H. (1993). Switching genes on at the START of the yeast cell cycle. The pharmacology of cell differentiation. Esteve Foundation Symposium Volume (ed. Rifkind, RA.). :107-21
1992
Beug, H., Doederlein, G., Zenke, M. (1992). Independent modulation of differentiation and proliferation in erythroid progenitors. Nuclear Processes and Oncogenes. :53-84
Boehmelt, G., Walker, A., Kabrun, N., Mellitzer, G., Beug, H., Zenke, M., Enrietto, PJ. (1992). Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression. EMBO J. 11(12):4641-52 (abstract)
Engel, JD., Beug, H., LaVail, JH., Zenke, MW., Mayo, K., Leonard, MW., Foley, KP., Yang, Z., Kornhauser, JM., Ko, LJ. (1992). cis and trans regulation of tissue-specific transcription. J Cell Sci Suppl. 16:21-31 (abstract)
Fuerstenberg, S., Leitner, I., Schroeder, C., Schwarz, H., Vennström, B., Beug, H. (1992). Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype. EMBO J. 11(9):3355-65 (abstract)
Ghysdael, J., Beug, H. (1992). The leukaemia oncogene v-erbA: a dominant negative version of ligand dependent transcription factors that regulates red cell differentiation? Cancer Surv. 14:169-80 (abstract)
Hayman, MJ., Beug, H. (1992). Avian erythroblastosis: a model system to study oncogene co-operation in leukemia. Cancer Surv. 15:53-68 (abstract)
Kennedy, M., Beug, H., Wagner, EF., Keller, G. (1992). Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene. Blood. 79(1):180-90 (abstract)
Killisch, I., Steinlein, P., Römisch, K., Hollinshead, R., Beug, H., Griffiths, G. (1992). Characterization of early and late endocytic compartments of the transferrin cycle. Transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome. J Cell Sci. 103 ( Pt 1):211-32 (abstract)
Larsen, J., Beug, H., Hayman, MJ. (1992). The v-ski oncogene cooperates with the v-sea oncogene in erythroid transformation by blocking erythroid differentiation. Oncogene. 7(10):1903-11 (abstract)
Reichmann, E., Schwarz, H., Deiner, EM., Leitner, I., Eilers, M., Berger, J., Busslinger, M., Beug, H. (1992). Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. Cell. 71(7):1103-16 (abstract)
Schroeder, C., Gibson, L., Beug, H. (1992). The v-erbA oncogene requires cooperation with tyrosine kinases to arrest erythroid differentiation induced by ligand-activated endogenous c-erbA and retinoic acid receptor. Oncogene. 7(2):203-16 (abstract)
Schroeder, C., Gibson, L., Zenke, M., Beug, H. (1992). Modulation of normal erythroid differentiation by the endogenous thyroid hormone and retinoic acid receptors: a possible target for v-erbA oncogene action. Oncogene. 7(2):217-27 (abstract)
Ulrich, E., Boehmelt, G., Bird, A., Beug, H. (1992). Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation. Genes Dev. 6(5):876-87 (abstract)
1991
Benn, A., Antoine, M., Beug, H., Niessing, J. (1991). Primary structure and expression of a chicken cDNA encoding a protein with zinc-finger motifs. Gene. 106(2):207-12 (abstract)
Beug, H., Vennström, B. (1991). Avian erythroleukemia: Possible mechanisms involved in v-erbA oncogene function. Nuclear Hormone Receptors (ed. Parker, MD.). :355-75
Disela, C., Glineur, C., Bugge, T., Sap, J., Stengl, G., Dodgson, J., Stunnenberg, H., Beug, H., Zenke, M. (1991). v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII. Genes Dev. 5(11):2033-47 (abstract)
Disela, C., Walter, C., Dodgson, J., Stunnenberg, H., Beug, H., Zenke, M. (1991). The v-erbA oncoprotein efficiently suppresses erythrocyte-specific CA II expression. Proceedings on carbonic anhydrases (ed. Botrè, F., Gros, G., Storey, BT.. :139-43
Morrison, LE., Boehmelt, G., Beug, H., Enrietto, PJ. (1991). Expression of v-rel in a replication competent virus: transformation and biochemical characterization. Oncogene. 6(9):1657-66 (abstract)
Vennström, B., Beug, H., Damm, K., Engel, D., Gehring, U., Graf, T., Munoz, A., Sap, J., Zenke, M. (1991). Biological effects of the v-erbA oncogene in transformation of avian erythroid cells. Molecular Mechanisms in Cellular Growth and Differentiation (eds. Bellve, AR., Vogel, JH.). :137-47
Zenke, M., Khazaie, K., Beug, H. (1991). V-myc-transformed macrophages expressing the normal human EGF receptor are induced to proliferate by EGF via a non-autocrine mechanism. Molecular Biology of Haematopiesis (eds. Sachs, I., Abraham, NG., Weidemann, C., Konwalinka, G.. :453-67
1990
Cotten, M., Längle-Rouault, F., Kirlappos, H., Wagner, E., Mechtler, K., Zenke, M., Beug, H., Birnstiel, ML. (1990). Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. Proc Natl Acad Sci U S A. 87(11):4033-7 (abstract)
Forrest, D., Muñoz, A., Raynoschek, C., Vennström, B., Beug, H. (1990). Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repression. Oncogene. 5(3):309-16 (abstract)
Fuerstenberg, S., Beug, H., Introna, M., Khazaie, K., Muñoz, A., Ness, S., Nordström, K., Sap, J., Stanley, I., Zenke, M. (1990). Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector. J Virol. 64(12):5891-902 (abstract)
Glineur, C., Zenke, M., Beug, H., Ghysdael, J. (1990). Phosphorylation of the v-erbA protein is required for its function as an oncogene. Genes Dev. 4(10):1663-76 (abstract)
Schroeder, C., Raynoschek, C., Fuhrmann, U., Damm, K., Vennström, B., Beug, H. (1990). The v-erb A oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors. Oncogene. 5(10):1445-53 (abstract)
Wagner, E., Zenke, M., Cotten, M., Beug, H., Birnstiel, ML. (1990). Transferrin-polycation conjugates as carriers for DNA uptake into cells. Proc Natl Acad Sci U S A. 87(9):3410-4 (abstract)
Yamamoto, M., Ko, LJ., Leonard, MW., Beug, H., Orkin, SH., Engel, JD. (1990). Activity and tissue-specific expression of the transcription factor NF-E1 multigene family. Genes Dev. 4(10):1650-62 (abstract)
Zenke, M., Muñoz, A., Sap, J., Vennström, B., Beug, H. (1990). v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA. Cell. 61(6):1035-49 (abstract)
Zenke, M., Steinlein, P., Wagner, E., Cotten, M., Beug, H., Birnstiel, ML. (1990). Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells. Proc Natl Acad Sci U S A. 87(10):3655-9 (abstract)
1989
Beug, H., Graf, T. (1989). Co-operation between viral oncogenes in avian erythroid and myeloid leukaemia. Eur J Clin Invest. 19(6):491-502 (abstract)
Fuhrmann, U., Vennström, B., Beug, H. (1989). The mutated, myeloid cell-specific growth factor receptor v-fms transforms avian erythroid but not myeloid cells. Genes Dev. 3(12B):2072-82 (abstract)
1988
Frykberg, L., Metz, T., Brady, G., Introna, M., Beug, H., Vennström, B., Graf, T. (1988). A point mutation in the DNA binding domain of the v-myb oncogene of E26 virus confers temperature sensitivity for transformation of myelomonocytic cells. Oncogene Res. 3(4):313-22 (abstract)
Graf, T., Kahn, P., Leutz, A., Beug, H., Vennström, B. (1988). Cooperativity of viral oncogenes in avian leukaemia. IARC Sci Publ. (92):165-70 (abstract)
Khazaie, K., Dull, TJ., Graf, T., Schlessinger, J., Ullrich, A., Beug, H., Vennström, B. (1988). Truncation of the human EGF receptor leads to differential transforming potentials in primary avian fibroblasts and erythroblasts. EMBO J. 7(10):3061-71 (abstract)
Knight, J., Beug, H., Marshall, J., Hayman, MJ. (1988). Abnormal glycosylation of the env-sea oncogene product inhibits its proteolytic cleavage and blocks its transforming ability. Oncogene. 2(4):317-26 (abstract)
Knight, J., Zenke, M., Disela, C., Kowenz, E., Vogt, P., Engel, JD., Hayman, MJ., Beug, H. (1988). Temperature-sensitive v-sea transformed erythroblasts: a model system to study gene expression during erythroid differentiation. Genes Dev. 2(2):247-58 (abstract)
Leutz, A., Beug, H., Walter, C., Graf, T. (1988). Hematopoietic growth factor glycosylation. Multiple forms of chicken myelomonocytic growth factor. J Biol Chem. 263(8):3905-11 (abstract)
Muñoz, A., Zenke, M., Gehring, U., Sap, J., Beug, H., Vennström, B. (1988). Characterization of the hormone-binding domain of the chicken c-erbA/thyroid hormone receptor protein. EMBO J. 7(1):155-9 (abstract)
1987
Beug, H., Blundell, PA., Graf, T. (1987). Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus. Genes Dev. 1(3):277-86 (abstract)
Damm, K., Beug, H., Graf, T., Vennström, B. (1987). A single point mutation in erbA restores the erythroid transforming potential of a mutant avian erythroblastosis virus (AEV) defective in both erbA and erbB oncogenes. EMBO J. 6(2):375-82 (abstract)
Jansson, M., Beug, H., Gray, C., Graf, T., Vennström, B. (1987). Defective v-erbB genes can be complemented by v-erbA in erythroblast and fibroblast transformation. Oncogene. 1(2):167-73 (abstract)
Kowenz, E., Leutz, A., Döderlein, G., Graf, T., Beug, H. (1987). ts-oncogene-transformed erythroleukemic cells: a novel test system for purifying and characterizing avian erythroid growth factors. Haematol Blood Transfus. 31:199-209 (abstract)
Ness, SA., Beug, H., Graf, T. (1987). v-myb dominance over v-myc in doubly transformed chick myelomonocytic cells. Cell. 51(1):41-50 (abstract)
Scotting, P., Vennstrom, B., Jansen, M., Graf, T., Beug, H., Hayman, MJ. (1987). Common site of mutation in the erbB gene of avian erythroblastosis virus mutants that are temperature sensitive for transformation. Oncogene Res. 1(3):265-78 (abstract)
1986
Beug, H., Hayman, MJ., Raines, MB., Kung, HJ., Vennström, B. (1986). Rous-associated virus 1-induced erythroleukemic cells exhibit a weakly transformed phenotype in vitro and release c-erbB-containing retroviruses unable to transform fibroblasts. J Virol. 57(3):1127-38 (abstract)
Bos, TJ., Beug, H., Graf, T., Hayman, M., Maki, Y., Uckert, W., Vogt, PK. (1986). Two new retroviral onc genes, sea and jun. Princess Takamatsu Symp. 17:23-30 (abstract)
Choi, OR., Trainor, C., Graf, T., Beug, H., Engel, JD. (1986). A single amino acid substitution in v-erbB confers a thermolabile phenotype to ts167 avian erythroblastosis virus-transformed erythroid cells. Mol Cell Biol. 6(5):1751-9 (abstract)
Hayman, MJ., Kitchener, G., Knight, J., McMahon, J., Watson, R., Beug, H. (1986). Analysis of the autophosphorylation activity of transformation defective mutants of avian erythroblastosis virus. Virology. 150(1):270-5 (abstract)
Kahn, P., Frykberg, L., Brady, C., Stanley, I., Beug, H., Vennström, B., Graf, T. (1986). v-erbA cooperates with sarcoma oncogenes in leukemic cell transformation. Cell. 45(3):349-56 (abstract)
Sap, J., Muñoz, A., Damm, K., Goldberg, Y., Ghysdael, J., Leutz, A., Beug, H., Vennström, B. (1986). The c-erb-A protein is a high-affinity receptor for thyroid hormone. Nature. 324(6098):635-40 (abstract)
Schmidt, JA., Marshall, J., Hayman, MJ., Beug, H. (1986). Primitive series embryonic chick erythrocytes express the transferrin receptor. Exp Cell Res. 164(1):71-8 (abstract)
Schmidt, JA., Marshall, J., Hayman, MJ., Doderlein, G., Beug, H. (1986). Monoclonal antibodies to novel erythroid differentiation antigens reveal specific effects of oncogenes on the leukaemic cell phenotype. Leuk Res. 10(3):257-72 (abstract)
Schmidt, JA., Marshall, J., Hayman, MJ., Ponka, P., Beug, H. (1986). Control of erythroid differentiation: possible role of the transferrin cycle. Cell. 46(1):41-51 (abstract)
von Weizsäcker, F., Beug, H., Graf, T. (1986). Temperature-sensitive mutants of MH2 avian leukemia virus that map in the v-mil and the v-myc oncogene respectively. EMBO J. 5(7):1521-7 (abstract)
1985
Adkins, B., Beug, H., Graf, T. (1985). Protein synthesis in differentiating normal and leukemic erythroid cells. J Cell Physiol. 123(2):269-76 (abstract)
Beug, H., Hayman, MJ., Graf, T., Benedict, SH., Wallbank, AM., Vogt, PK. (1985). S13, a rapidly oncogenic replication-defective avian retrovirus. Virology. 145(1):141-53 (abstract)
Beug, H., Kahn, P., Doederlein, G., Hayman, MJ., Graf, T. (1985). Characterization of hematopoietic cells transformed in vitro by AEV-H, a v-erbB-containing avian erythroblastosis virus. Haematol Blood Transfus. 29:290-7 (abstract)
Beug, H., Kahn, P., Vennström, B., Hayman, MJ., Graf, T. (1985). How do retroviral oncogenes induce transformation in avian erythroid cells? Proc R Soc Lond B Biol Sci. 226(1242):121-6 (abstract)
Hayman, MJ., Kitchener, G., Vogt, PK., Beug, H. (1985). The putative transforming protein of S13 avian erythroblastosis virus is a transmembrane glycoprotein with an associated protein kinase activity. Proc Natl Acad Sci U S A. 82(23):8237-41 (abstract)
Hayman, MJ., Schmidt, JA., Kitchener, G., Marshall, J., Beug, H. (1985). Characterization of the number of carbohydrate chains on the avian erythroblastosis virus erb B gene product and their role in transformation. Haematol Blood Transfus. 29:284-9 (abstract)
Lax, I., Kris, R., Sasson, I., Ullrich, A., Hayman, MJ., Beug, H., Schlessinger, J. (1985). Activation of c-erbB in avian leukosis virus-induced erythroblastosis leads to the expression of a truncated EGF receptor kinase. EMBO J. 4(12):3179-82 (abstract)
Moelling, K., Pfaff, E., Beug, H., Beimling, P., Bunte, T., Schaller, HE., Graf, T. (1985). DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants. Cell. 40(4):983-90 (abstract)
Schmidt, JA., Beug, H., Hayman, MJ. (1985). Effects of inhibitors of glycoprotein processing on the synthesis and biological activity of the erb B oncogene. EMBO J. 4(1):105-12 (abstract)
1984
Beug, H., Hayman, MJ. (1984). Temperature-sensitive mutants of avian erythroblastosis virus: surface expression of the erbB product correlates with transformation. Cell. 36(4):963-72 (abstract)
Beug, H., Leutz, A., Kahn, P., Graf, T. (1984). Ts mutants of E26 leukemia virus allow transformed myeloblasts, but not erythroblasts or fibroblasts, to differentiate at the nonpermissive temperature. Cell. 39(3 Pt 2):579-88 (abstract)
Hayman, MJ., Beug, H. (1984). Identification of a form of the avian erythroblastosis virus erb-B gene product at the cell surface. Nature. 309(5967):460-2 (abstract)
Kahn, P., Adkins, B., Beug, H., Graf, T. (1984). src- and fps-containing avian sarcoma viruses transform chicken erythroid cells. Proc Natl Acad Sci U S A. 81(22):7122-6 (abstract)
Leutz, A., Beug, H., Graf, T. (1984). Purification and characterization of cMGF, a novel chicken myelomonocytic growth factor. EMBO J. 3(13):3191-7 (abstract)
1983
Coll, J., Saule, S., Martin, P., Raes, MB., Lagrou, C., Graf, T., Beug, H., Simon, IE., Stehelin, D. (1983). The cellular oncogenes c-myc, c-myb and c-erb are transcribed in defined types of avian hematopoietic cells. Exp Cell Res. 149(1):151-62 (abstract)
Frykberg, L., Palmieri, S., Beug, H., Graf, T., Hayman, MJ., Vennström, B. (1983). Transforming capacities of avian erythroblastosis virus mutants deleted in the erbA or erbB oncogenes. Cell. 32(1):227-38 (abstract)
Graf, T., Beug, H. (1983). Role of the v-erbA and v-erbB oncogenes of avian erythroblastosis virus in erythroid cell transformation. Cell. 34(1):7-9 (abstract)
Hayman, MJ., Ramsay, GM., Savin, K., Kitchener, G., Graf, T., Beug, H. (1983). Identification and characterization of the avian erythroblastosis virus erbB gene product as a membrane glycoprotein. Cell. 32(2):579-88 (abstract)
Kornfeld, S., Beug, H., Doederlein, G., Graf, T. (1983). Detection of avian hematopoietic cell surface antigens with monoclonal antibodies to myeloid cells. Their distribution on normal and leukemic cells of various lineages. Exp Cell Res. 143(2):383-94 (abstract)
1982
Beug, H., Doederlein, G., Freudenstein, C., Graf, T. (1982). Erythroblast cell lines transformed by a temperature-sensitive mutant of avian erythroblastosis virus: a model system to study erythroid differentiation in vitro. J Cell Physiol Suppl. 1:195-207 (abstract)
Beug, H., Hayman, MJ., Graf, T. (1982). Myeloblasts transformed by the avian acute leukemia virus E26 are hormone-dependent for growth and for the expression of a putative myb-containing protein, p135 E26. EMBO J. 1(9):1069-73 (abstract)
Beug, H., Palmieri, S., Freudenstein, C., Zentgraf, H., Graf, T. (1982). Hormone-dependent terminal differentiation in vitro of chicken erythroleukemia cells transformed by ts mutants of avian erythroblastosis virus. Cell. 28(4):907-19 (abstract)
Freudenstein, C., Beug, H., Palmieri, S., Graf, T. (1982). Expression of embryonic haemoglobin in tsAEV-transformed embryonic erythroid cells during temperature-induced differentiation. Differentiation. 22(3):231-4 (abstract)
Hayman, MJ., Beug, H., Savin, KW. (1982). Changes in the expression of membrane antigens during the differentiation of chicken erythroblasts. J Cell Biochem. 18(3):351-62 (abstract)
Palmieri, S., Beug, H., Graf, T. (1982). Isolation and characterization of four new temperature-sensitive mutants of avian erythroblastosis virus (AEV). Virology. 123(2):296-311 (abstract)
Radke, K., Beug, H., Kornfeld, S., Graf, T. (1982). Transformation of both erythroid and myeloid cells by E26, an avian leukemia virus that contains the myb gene. Cell. 31(3 Pt 2):643-53 (abstract)
Renkawitz, R., Beug, H., Graf, T., Matthias, P., Grez, M., Schütz, G. (1982). Expression of a chicken lysozyme recombinant gene is regulated by progesterone and dexamethasone after microinjection into oviduct cells. Cell. 31(1):167-76 (abstract)
Weintraub, H., Beug, H., Groudine, M., Graf, T. (1982). Temperature-sensitive changes in the structure of globin chromatin in lines of red cell precursors transformed by ts-AEV. Cell. 28(4):931-40 (abstract)
1981
Beug, H., Graf, T., Hayman, MJ. (1981). Production and characterization of antisera specific for the erb-portion of p75, the presumptive transforming protein of avian erythroblastosis virus. Virology. 111(1):201-10 (abstract)
Beug, H., Müller, H., Grieser, S., Doederlein, G., Graf, T. (1981). Hematopoietic cells transformed in vitro by REVT avian reticuloendotheliosis virus express characteristics of very immature lymphoid cells. Virology. 115(2):295-309 (abstract)
Graf, T., Royer-Pokora, B., Korzeniewska, E., Grieser, S., Beug, H. (1981). Characterization of the hematopoietic target cells of defective avian leukemia viruses by velocity sedimentation and density gradient centrifugation analyses. Haematol Blood Transfus. 26:417-23 (abstract)
Graf, T., von Kirchbach, A., Beug, H. (1981). Characterization of the hematopoietic target cells of AEV, MC29 and AMV avian leukemia viruses. Exp Cell Res. 131(2):331-43 (abstract)
Hauser, H., Graf, T., Beug, H., Greiser-Wilke, I., Lindenmaier, W., Grez, M., Land, H., Giesecke, K., Schütz, G. (1981). Structure of the lysozyme gene and expression in the oviduct and macrophages. Haematol Blood Transfus. 26:175-8 (abstract)
Matthews, TJ., Broughton, EM., Weinhold, KJ., Bolognesi, DP., Graf, T., Beug, H. (1981). Clonal isolate of the simian sarcoma virus codes for a Gag-related 65,000-dalton protein. Virology. 114(1):124-31 (abstract)
Savin, KW., Beug, H. (1981). Cell-surface glycoprotein synthesis during differentiation of chicken erythroblasts transformed by temperature-sensitive avian erythroblastosis virus. Cell Differ. 10(3):163-71 (abstract)
1980
Beug, H., Graf, T. (1980). Transformation parameters of chicken embryo fibroblasts infected with the ts34 mutant of avian erythroblastosis virus. Virology. 100(2):348-56 (abstract)
Beug, H., Kitchener, G., Doederlein, G., Graf, T., Hayman, MJ. (1980). Mutant of avian erythroblastosis virus defective for erythroblast transformation: deletion in the erb portion of p75 suggests function of the protein in leukemogenesis. Proc Natl Acad Sci U S A. 77(11):6683-6 (abstract)
Graf, T., Beug, H., Hayman, MJ. (1980). Target cell specificity of defective avian leukemia viruses: hematopoietic target cells for a given virus type can be infected but not transformed by strains of a different type. Proc Natl Acad Sci U S A. 77(1):389-93 (abstract)
Graf, T., Beug, H., Roussel, M., Saule, S., Stehelin, D., Hayman, MJ. (1980). Avian leukaemia viruses and haematopoietic cell differentiation. Br J Cancer. 41(4):659-61 (abstract)
Graf, T., Beug, H., von Kirchbach, A., Hayman, MJ. (1980). Three new types of viral oncogenes in defective avian leukemia viruses. II. Biological, genetic, and immunochemical evidence. Cold Spring Harb Symp Quant Biol. 44 Pt 2,:1225-34 (abstract)
Hayman, MJ., Ramsay, G., Kitchener, G., Graf, T., Beug, H., Roussel, M., Saule, S., Stehelin, D. (1980). Cell transformation by avian defective leukaemia viruses. Proc R Soc Lond B Biol Sci. 210(1180):397-409 (abstract)
1979
Beug, H., von Kirchbach, A., Döderlein, G., Conscience, JF., Graf, T. (1979). Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation. Cell. 18(2):375-90 (abstract)
Graf, T., Oker-Blom, N., Todorov, TG., Beug, H. (1979). Transforming capacities and defectiveness of avian leukemia viruses OK10 and E 26. Virology. 99(2):431-6 (abstract)
Graf, T., von Kirchbach, A., Beug, H. (1979). Mechanism of leukemogenesis and of target cell specificity by defective avian leukemia viruses: a hypothesis. Haematol Blood Transfus. 23:429-38 (abstract)
Roussel, M., Saule, S., Lagrou, C., Rommens, C., Beug, H., Graf, T., Stehelin, D. (1979). Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation. Nature. 281(5731):452-5 (abstract)
Royer-Pokora, B., Grieser, S., Beug, H., Graf, T. (1979). Mutant avian erythroblastosis virus with restricted target cell specificity. Nature. 282(5740):750-2 (abstract)
1978
Beug, H., Claviez, M., Jockusch, BM., Graf, T. (1978). Differential expression of Rous Sarcoma virus-specific transformation parameters in enucleated cells. Cell. 14(4):843-56 (abstract)
Deinhardt, F., Bergholz, C., Hunsmann, G., Schneider, J., Thiel, HJ., Beug, H., Schäfer, W. (1978). Studies of simian sarcoma and simian sarcoma-associated virus. I. Analysis of viral structural proteins, and preparation and characterization of antiserum specific for viral envelope components. Z Naturforsch C. 33(11-12):969-80 (abstract)
Gerisch, G., Müller, K., Beug, H. (1978). Dictyostelium, a microbial model for biochemical studies on cell recognition. Biochem Soc Trans. 6(3):481-6 (abstract)
Graf, T., Ade, N., Beug, H. (1978). Temperature-sensitive mutant of avian erythroblastosis virus suggests a block of differentiation as mechanism of leukaemogenesis. Nature. 275(5680):496-501 (abstract)
Graf, T., Beug, H. (1978). Avian leukemia viruses: interaction with their target cells in vivo and in vitro. Biochim Biophys Acta. 516(3):269-99 (abstract)
Royer-Pokora, B., Beug, H., Claviez, M., Winkhardt, HJ., Friis, RR., Graf, T. (1978). Transformation parameters in chicken fibroblasts transformed by AEV and MC29 avian leukemia viruses. Cell. 13(4):751-60 (abstract)
Thiel, HJ., Beug, H., Graf, T., Schwarz, H., Schäfer, W., Bergholz, C., Deinhardt, F. (1978). Studies of simian sarcoma and simian sarcoma-associated virus. II. Isolation of the major viral glycoprotein, properties of this component and its specific antiserum. Virology. 90(2):360-5 (abstract)
1977
Beug, H., Graf, T. (1977). Isolation of clonal strains of chicken embryo fibroblasts. Exp Cell Res. 107(2):417-28 (abstract)
Graf, T., Fink, D., Beug, H., Royer-Pokora, B. (1977). Oncornavirus-induced sarcoma formation obscured by rapid development of lethal leukemia. Cancer Res. 37(1):59-63 (abstract)
Graf, T., Royer-Pokora, B., Meyer-Glauner, W., Beug, H. (1977). Tumor specificity of acute avian leukemia viruses reflected by their transformation target cell specificity in vitro. Med Microbiol Immunol. 164(1-3):139-53 (abstract)
1976
Beug, H., Peters, JH., Graf, T. (1976). Expression of virus specific morphological cell transformation induced in enucleated cells. Z Naturforsch C. 31(11-12):766-8 (abstract)
Graf, T., Beug, H. (1976). A novel type of cellular variant with altered expression of virus-induced cell transformation. Virology. 72(1):283-6 (abstract)
Graf, T., Royer-Pokora, B., Beug, H. (1976). Target cells for transformation with avian leukosis viruses. Hamatol Bluttransfus. 19:169-76 (abstract)
Graf, T., Royer-Pokora, B., Schubert, GE., Beug, H. (1976). Evidence for the multiple oncogenic potential of cloned leukemia virus: in vitro and in vitro studies with avian erythroblastosis virus. Virology. 71(2):423-33 (abstract)
1973
Beug, H., Katz, FE., Gerisch, G. (1973). Dynamics of antigenic membrane sites relating to cell aggregation in Dictyostelium discoideum. J Cell Biol. 56(3):647-58 (abstract)
Beug, H., Katz, FE., Stein, A., Gerisch, G. (1973). Quantitation of membrane sites in aggregating Dictyostelium cells by use of tritiated univalent antibody. Proc Natl Acad Sci U S A. 70(11):3150-4 (abstract)
Riedel, V., Gerisch, G., Müller, E., Beug, H. (1973). Defective cyclic adenosine-3', 5'-phosphate-phosphodiesterase regulation in morphogenetic mutants of Dictyostelium discoideum. J Mol Biol. 74(4):573-85 (abstract)
1972
Beug, H., Gerisch, G. (1972). A micromethod for routine measurement of cell agglutination and dissociation. J Immunol Methods. 2(1):49-57 (abstract)
Gerisch, G., Malchow, D., Riedel, V., Beug, H. (1972). Cell communication by chemical signals and the regulation of cyclic AMP in the development of a microorganism, Dictyostelium discoideum. Hoppe Seylers Z Physiol Chem. 353(5):684-5 (abstract)
1971
Beug, H., Gerisch, G., Müller, E. (1971). Cell dissociation: univalent antibodies as a possible alternative to proteolytic enzymes. Science. 173(998):742-3 (abstract)
1970
Beug, H., Gerisch, G., Kempff, S., Riedel, V., Cremer, G. (1970). Specific inhibition of cell contact formation in Dictyostelium by univalent antibodies. Exp Cell Res. 63(1):147-58 (abstract)
1969
Beug, H., Gerisch, G. (1969). [Monovalent fragments of antibodies for the analysis of cell membrane functions] Naturwissenschaften. 56(7):374 (abstract)
1966
Gerisch, G., Normann, I., Beug, H. (1966). [Rhythm of cell orientation and velocity of movement in the chemotactic reaction system of Dictyostelium discoideum] Naturwissenschaften. 53(23):618 (abstract)

Home |

Seminars |

PhD Program |

Sitemap